Page last updated: 2024-08-18

glyoxal and Diabetes Mellitus

glyoxal has been researched along with Diabetes Mellitus in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (19.05)29.6817
2010's13 (61.90)24.3611
2020's4 (19.05)2.80

Authors

AuthorsStudies
Bellenfant, S; Berthod, F; Cadau, S; De Serres-Bérard, T; Lemarchand, M; Thouin, K1
Broers, NJH; Canaud, B; Christiaans, MHL; Cornelis, T; Gauly, A; Hermans, MMH; Konings, CJAM; Kooman, JP; Martens, RJH; Schalkwijk, CG; Scheijen, JLJM; Stifft, F; van der Sande, FM; Wirtz, JJJM1
Banerjee, S2
Akhter, A; Kausar, MA; Saeed, M; Siddiqui, AJ; Singh, R1
Feng, Y; Liu, Q; Liu, X; Lou, K; Ma, S; Meng, X; Song, X; Wang, C; Wang, W; Wang, X; Xu, H1
Campillo, N; Fernández-García, AJ; Hernández-Córdoba, M; Motas, M; Pastor-Belda, M; Pérez-Cárceles, MD; Viñas, P1
Arcanjo, NMO; Estévez, M; Luna, C; Madruga, MS1
Dhananjayan, K; Harman, DG; Irrgang, F; Moran, C; Münch, G; Raju, R; Srikanth, V1
Brown, KL; Chetyrkin, S; Hudson, B; Voziyan, P1
Ahmad, K; Ahmad, S; Akhter, F; Khan, MS; Saeed, M; Shahab, U; Srivastava, AK; Tabrez, S1
Rabbani, N; Thornalley, PJ1
Butler, ES; Eubank, TD; Kotha, SR; Kuppusamy, ML; Kuppusamy, P; Marsh, CB; Parinandi, NL; Roy, S; Sherwani, SI; Sliman, SM; Stern, DM1
Hofmann, B; Nass, N; Presek, P; Silber, RE; Simm, A; Vogel, K1
Abina, EA; Konovalova, GG; Kumskova, EM; Lankin, VZ; Tikhaze, AK; Viigimaa, M; Vlasik, TN; Yanushevskaya, EV; Zemtsovskaya, G1
Shiriaeva, IuK; Titov, VN1
Higashi, T; Min, JZ; Toyo'oka, T; Yamamoto, M; Yu, HF1
Arain, R; Kandhro, AJ; Khuhawar, MY; Memon, SQ; Mirza, MA1
Chellan, P; Duve, Y; Glomb, MA; Jiang, CL; Madhun, Z; Nagaraj, RH; Sady, C1
Bierhaus, A; Häring, HU; Lehmann, R; Nawroth, PP; Schleicher, ED1
Chock, PB; Kang, SO; Lee, C; Yim, HS; Yim, MB1

Reviews

5 review(s) available for glyoxal and Diabetes Mellitus

ArticleYear
The Role of Glyoxalase in Glycation and Carbonyl Stress Induced Metabolic Disorders.
    Current protein & peptide science, 2020, Volume: 21, Issue:9

    Topics: Aging; Deoxyglucose; Diabetes Mellitus; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Isoenzymes; Lactoylglutathione Lyase; Metabolic Diseases; Neurodegenerative Diseases; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Reactive Oxygen Species; Schiff Bases; Signal Transduction

2020
Site-specific AGE modifications in the extracellular matrix: a role for glyoxal in protein damage in diabetes.
    Clinical chemistry and laboratory medicine, 2014, Jan-01, Volume: 52, Issue:1

    Topics: Aldehydes; Diabetes Mellitus; Extracellular Matrix; Extracellular Matrix Proteins; Glycation End Products, Advanced; Glyoxal; Humans; Ketones

2014
Dicarbonyl stress in cell and tissue dysfunction contributing to ageing and disease.
    Biochemical and biophysical research communications, 2015, Mar-06, Volume: 458, Issue:2

    Topics: Aging; Aldehydes; Cardiovascular Diseases; Deoxyglucose; Diabetes Mellitus; Glyoxal; Humans; Inflammation; Kidney Diseases; Models, Biological; Oxidative Stress; Pyruvaldehyde; Stress, Physiological

2015
Chemistry and pathobiology of advanced glycation end products.
    Contributions to nephrology, 2001, Issue:131

    Topics: Aging; Deoxyglucose; Diabetes Mellitus; Diabetic Nephropathies; Gene Expression Regulation; Glucose; Glycation End Products, Advanced; Glycoproteins; Glycosylation; Glyoxal; Humans; Kidney Glomerulus; Lipid Peroxidation; NF-kappa B; Oxidative Stress; Pyruvaldehyde; Reactive Oxygen Species

2001
Protein glycation: creation of catalytic sites for free radical generation.
    Annals of the New York Academy of Sciences, 2001, Volume: 928

    Topics: Aging; Alanine; Amino Acids; Animals; Arteriosclerosis; Catalytic Domain; Cations; Cattle; Cytochrome c Group; Diabetes Mellitus; Electrons; Free Radicals; Glycation End Products, Advanced; Glycosylation; Glyoxal; Maillard Reaction; Oxidation-Reduction; Oxidative Stress; Proteins; Pyruvaldehyde; Schiff Bases; Serum Albumin, Bovine

2001

Trials

1 trial(s) available for glyoxal and Diabetes Mellitus

ArticleYear
Relations of advanced glycation endproducts and dicarbonyls with endothelial dysfunction and low-grade inflammation in individuals with end-stage renal disease in the transition to renal replacement therapy: A cross-sectional observational study.
    PloS one, 2019, Volume: 14, Issue:8

    Topics: Adult; Aged; Biomarkers; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus; Endothelium, Vascular; Female; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Ornithine; Renal Dialysis

2019

Other Studies

15 other study(ies) available for glyoxal and Diabetes Mellitus

ArticleYear
In vitro glycation of a tissue-engineered wound healing model to mimic diabetic ulcers.
    Biotechnology and bioengineering, 2023, Volume: 120, Issue:6

    Topics: Animals; Diabetes Mellitus; Diabetic Foot; Endothelial Cells; Glycation End Products, Advanced; Glyoxal; Humans; Maillard Reaction; Wound Healing

2023
Effect of Glyoxal Modification on a Critical Arginine Residue (Arg-31α) of Hemoglobin: Physiological Implications of Advanced Glycated end Product an
    Protein and peptide letters, 2020, Volume: 27, Issue:8

    Topics: Circular Dichroism; Diabetes Mellitus; Glycation End Products, Advanced; Glyoxal; Hemoglobins; Humans; Protein Processing, Post-Translational

2020
Fluorophore-Promoted Facile Deprotonation and Exocyclic Five-Membered Ring Cyclization for Selective and Dynamic Tracking of Labile Glyoxals.
    Analytical chemistry, 2020, 10-20, Volume: 92, Issue:20

    Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Cyclization; Diabetes Mellitus; Diabetes Mellitus, Experimental; Endoplasmic Reticulum; Fluorescent Dyes; Formaldehyde; Glyoxal; HeLa Cells; Humans; Mass Spectrometry; Mice; Microscopy, Fluorescence

2020
Glyoxal and methylglyoxal as urinary markers of diabetes. Determination using a dispersive liquid-liquid microextraction procedure combined with gas chromatography-mass spectrometry.
    Journal of chromatography. A, 2017, Aug-04, Volume: 1509

    Topics: Adult; Diabetes Mellitus; Female; Gas Chromatography-Mass Spectrometry; Glyoxal; Humans; Limit of Detection; Liquid Phase Microextraction; Male; Middle Aged; Pyruvaldehyde

2017
Glyoxal-induced modification enhances stability of hemoglobin and lowers iron-mediated oxidation reactions of the heme protein: An in vitro study.
    International journal of biological macromolecules, 2018, Volume: 107, Issue:Pt A

    Topics: Diabetes Mellitus; Ferric Compounds; Glycation End Products, Advanced; Glyoxal; Heme; Hemoglobins; Humans; Hydrogen Peroxide; Hydrophobic and Hydrophilic Interactions; Iron; Oxidation-Reduction; Protein Stability; Protein Structure, Secondary

2018
Antioxidant and pro-oxidant actions of resveratrol on human serum albumin in the presence of toxic diabetes metabolites: Glyoxal and methyl-glyoxal.
    Biochimica et biophysica acta. General subjects, 2018, Volume: 1862, Issue:9

    Topics: Antioxidants; Diabetes Mellitus; Glyoxal; Humans; Oxidants; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Reactive Oxygen Species; Resveratrol; Serum Albumin, Human; Stilbenes

2018
Determination of glyoxal and methylglyoxal in serum by UHPLC coupled with fluorescence detection.
    Analytical biochemistry, 2019, 05-15, Volume: 573

    Topics: Aged; Aged, 80 and over; Animals; Calibration; Chromatography, High Pressure Liquid; Diabetes Mellitus; Female; Fluorescent Dyes; Glyoxal; Humans; Hydrogen-Ion Concentration; Limit of Detection; Male; Mass Spectrometry; Middle Aged; Pteridines; Pyruvaldehyde; Reproducibility of Results

2019
Immunogenicity of DNA-advanced glycation end product fashioned through glyoxal and arginine in the presence of Fe³⁺: its potential role in prompt recognition of diabetes mellitus auto-antibodies.
    Chemico-biological interactions, 2014, Aug-05, Volume: 219

    Topics: Animals; Antigen-Antibody Complex; Arginine; Circular Dichroism; Comet Assay; Diabetes Mellitus; Diabetic Nephropathies; DNA; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Glyoxal; Humans; Leukocytes, Mononuclear; Microscopy, Fluorescence; Rabbits; Spectrophotometry, Ultraviolet

2014
Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine protection.
    Molecular and cellular biochemistry, 2010, Volume: 333, Issue:1-2

    Topics: Animals; Cattle; Cell Proliferation; Cells, Cultured; Cytoskeleton; Diabetes Mellitus; Endothelial Cells; Endothelium, Vascular; Glycation End Products, Advanced; Glyoxal; Guanidines; Neovascularization, Physiologic; Nitric Oxide Synthase; Protective Agents

2010
Glycation of PDGF results in decreased biological activity.
    The international journal of biochemistry & cell biology, 2010, Volume: 42, Issue:5

    Topics: Animals; Becaplermin; Blood Platelets; Cell Line; Cell Proliferation; Diabetes Mellitus; Extracellular Signal-Regulated MAP Kinases; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Hyperglycemia; Male; Mice; Mitogens; Phosphorylation; Pilot Projects; Platelet Activation; Platelet-Derived Growth Factor; Protein Multimerization; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Pyruvaldehyde; Recombinant Proteins; Signal Transduction; Wound Healing

2010
Interrelation between malonyl dialdehyde-dependent modification and cholesterol content in low-density lipoproteins.
    Bulletin of experimental biology and medicine, 2010, Volume: 149, Issue:2

    Topics: Adult; Atherosclerosis; Biomarkers; Blood Glucose; Cholesterol; Cholesterol, LDL; Diabetes Mellitus; Estonia; Glyoxal; Humans; Immunochemistry; Lipoproteins, LDL; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Pyruvaldehyde; Spectrophotometry

2010
[The glucose, glycotoxins and glycation products: the involvement into pathogenesis of microangiopathies, arteriolosclerosis and atherosclerosis].
    Klinicheskaia laboratornaia diagnostika, 2011, Issue:11

    Topics: Arteriolosclerosis; Atherosclerosis; Diabetes Mellitus; Diabetic Angiopathies; Glucose; Glutamic Acid; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Metabolic Networks and Pathways; Oxidation-Reduction; Proteolysis; Pyruvaldehyde; Vascular Diseases

2011
Rapid and sensitive determination of the intermediates of advanced glycation end products in the human nail by ultra-performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry.
    Analytical biochemistry, 2012, May-15, Volume: 424, Issue:2

    Topics: Adult; Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus; Female; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Humans; Limit of Detection; Male; Middle Aged; Nails; Phenylenediamines; Pyruvaldehyde; Reproducibility of Results; Signal-To-Noise Ratio; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2012
Determination of glyoxal and methylglyoxal in the serum of diabetic patients by MEKC using stilbenediamine as derivatizing reagent.
    Electrophoresis, 2007, Volume: 28, Issue:21

    Topics: Calibration; Chromatography, Micellar Electrokinetic Capillary; Diabetes Mellitus; Glyoxal; Humans; Pyruvaldehyde; Reproducibility of Results; Sensitivity and Specificity; Sodium Dodecyl Sulfate; Stilbenes

2007
Maillard reactions by alpha-oxoaldehydes: detection of glyoxal-modified proteins.
    Biochimica et biophysica acta, 2000, Sep-29, Volume: 1481, Issue:2

    Topics: Aged; Aging; Antibodies; Cataract; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lens, Crystalline; Lysine; Maillard Reaction; Proteins; Serum Albumin; Serum Albumin, Bovine; Serum Albumin, Human

2000