Page last updated: 2024-08-21

glycyrrhizic acid and Liver Dysfunction

glycyrrhizic acid has been researched along with Liver Dysfunction in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's10 (34.48)18.2507
2000's13 (44.83)29.6817
2010's5 (17.24)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fang, M; Fei, X; Gong, F; Hua, S; Ma, M; Zhang, Y1
Li, X; Liu, R; Sun, R1
Kuo, HC; Lee, KF; Tsai, JJ; Tsai, TH1
Gao, YJ; Han, JC; Yu, J1
Chakraborti, AS; Ray, D; Sil, R1
Cai, X; Cao, AP; Chen, CW; Chen, HZ; Chen, Y; Chen, YG; Fu, QC; Li, J; Lu, LG; Mao, YM; Sui, YH; Sun, Y; Wu, SM; Zeng, MD; Zhao, W1
Kageyama, K; Moriyama, T; Sakihara, S; Suda, T; Takayasu, S1
Levy, C; Lindor, KD; Seeff, LD1
Chawla, YK; Dhiman, RK1
Chen, WR; Cheng, X; Jin, HH; Liu, D; Ren, JB; Zheng, GP1
Bianchi, ME; Guidotti, LG; Iannacone, M; Müller, S; Sitia, G1
Schuppan, D; Stickel, F1
Cao, ZX; Zhao, XF; Zhao, ZF1
Abe, K; Ikeda, T; Inoue, H; Matsushita, T; Sato, T; Wake, K; Yoshida, T1
Muriel, P; Rivera-Espinoza, Y1
Gupta, MM; Khanuja, SP; Kumar, JK; Luqman, S; Negi, AS; Shanker, K1
Meng, F; Qiao, H; Sun, X; Tang, B1
Abe, K; Ikeda, T; Inoue, H; Sato, T; Wake, K1
Cadafalch, J; Estivill, X; Nolla, J; Puig, ML; Santesmasses, A1
Hayashi, K; Hayashi, R; Maruyama, K; Yanagisawa, N1
Chiba, S; Numazaki, K; Umetsu, M1
Kimura, T; Kurosaki, Y; Nakayama, T; Okamoto, M; Wang, Z1
Basnet, P; Hase, K; Kadota, S; Namba, T; Takahashi, T1
Basnet, P; Hase, K; Kadota, S; Matsushige, K; Namba, T1
Benner, K; Flora, K; Stolpman, D1
Cheng, TY; Lin, G; Nnane, IP1
Egashira, T; Kohno, M; Nagai, T; Yamanaka, Y1
Hayashi, Y; Ishiguro, I; Kuroda, K; Nagamura, Y; Nishida, K; Saito, S; Sasaki, Y1
Awazu, S; Ichikawa, T; Ishida, S; Sakiya, Y; Taira, Z1

Reviews

6 review(s) available for glycyrrhizic acid and Liver Dysfunction

ArticleYear
Natural products in licorice for the therapy of liver diseases: Progress and future opportunities.
    Pharmacological research, 2019, Volume: 144

    Topics: Animals; Anti-Inflammatory Agents; Biological Products; Glycyrrhiza; Glycyrrhizic Acid; Humans; Liver Diseases; Oxidative Stress

2019
Use of herbal supplements for chronic liver disease.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2004, Volume: 2, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Chronic Disease; Drug Combinations; Drugs, Chinese Herbal; Glycyrrhizic Acid; Humans; Liver Diseases; Phytotherapy; Plant Extracts; Plants, Medicinal; Silymarin

2004
Herbal medicines for liver diseases.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Drug Combinations; Glycyrrhizic Acid; Humans; Liver Diseases; Phyllanthus; Phytotherapy; Plant Extracts; Plant Preparations; Silymarin

2005
Herbal medicine in the treatment of liver diseases.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2007, Volume: 39, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Glycyrrhizic Acid; Humans; Liver Diseases; Magnoliopsida; Medicine, Chinese Traditional; Medicine, Kampo; Phytotherapy; Pyrrolizidine Alkaloids; Silymarin

2007
Beneficial drugs for liver diseases.
    Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Colchicine; Curcumin; Disease Models, Animal; Drug Combinations; Glycyrrhizic Acid; Humans; Interferons; Liver Diseases; Nitric Oxide; Plant Extracts; Resveratrol; S-Adenosylmethionine; Silymarin; Stilbenes; Thalidomide

2008
Recent advances in plant hepatoprotectives: a chemical and biological profile of some important leads.
    Medicinal research reviews, 2008, Volume: 28, Issue:5

    Topics: Animals; Cinnamates; Curcumin; Cytokines; Diterpenes; Glucosides; Glycyrrhizic Acid; Humans; Lignans; Liver; Liver Diseases; Phytotherapy; Plant Extracts; Plants; Protective Agents; Silymarin; Tetrahydronaphthalenes

2008

Trials

3 trial(s) available for glycyrrhizic acid and Liver Dysfunction

ArticleYear
[Magnesium isoglycyrrhizinate in the treatment of chronic liver diseases: a randomized, double-blind, multi-doses, active drug controlled, multi-center study].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2009, Volume: 17, Issue:11

    Topics: Alanine Transaminase; Anti-Inflammatory Agents; Aspartate Aminotransferases; Chronic Disease; Double-Blind Method; Fatty Liver; Female; Glycyrrhizic Acid; Humans; Injections, Intravenous; Liver; Liver Diseases; Liver Diseases, Alcoholic; Male; Saponins; Triterpenes

2009
[The use of diammonium glycyrrhizinate in the treatment of hepatic dysfunction in burn patients].
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2005, Volume: 21, Issue:5

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Burns; Female; Glycyrrhizic Acid; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Middle Aged

2005
Effect of compound glycyrrhizin injection on liver function and cellular immunity of children with infectious mononucleosis complicated liver impairment.
    Chinese journal of integrative medicine, 2006, Volume: 12, Issue:4

    Topics: Child; Child, Preschool; Female; Glycyrrhizic Acid; Humans; Immunity, Cellular; Infant; Infectious Mononucleosis; Injections; Liver; Liver Diseases; Male; T-Lymphocyte Subsets

2006

Other Studies

20 other study(ies) available for glycyrrhizic acid and Liver Dysfunction

ArticleYear
Glycyrrhizin attenuates hepatic ischemia-reperfusion injury by suppressing HMGB1-dependent GSDMD-mediated kupffer cells pyroptosis.
    International immunopharmacology, 2019, Volume: 68

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis Regulatory Proteins; Glycyrrhizic Acid; HMGB1 Protein; Interleukin-1beta; Intracellular Signaling Peptides and Proteins; Kupffer Cells; Liver; Liver Diseases; Male; Mice, Inbred C57BL; Peroxidase; Phosphate-Binding Proteins; Pyroptosis; Reperfusion Injury

2019
Glycyrrhizin represses total parenteral nutrition-associated acute liver injury in rats by suppressing endoplasmic reticulum stress.
    International journal of molecular sciences, 2013, Jun-14, Volume: 14, Issue:6

    Topics: Animals; Apoptosis; Bilirubin; Caspase 3; Cytokines; Endoplasmic Reticulum Stress; Glycyrrhizic Acid; Immunohistochemistry; Inflammation; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Liver; Liver Diseases; Male; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Parenteral Nutrition, Total; Phosphorylation; Rats, Sprague-Dawley; Reactive Nitrogen Species; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Transcription Factor CHOP; Triglycerides; Tyrosine

2013
Lipidomics investigation of reversal effect of glycyrrhizin (GL) towards lithocholic acid (LCA)-induced alteration of phospholipid profiles.
    Pharmaceutical biology, 2014, Volume: 52, Issue:12

    Topics: Alanine Transaminase; Animals; Glycyrrhizic Acid; Injections, Intraperitoneal; Lipid Metabolism; Lipids; Lithocholic Acid; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Phospholipids

2014
Glycyrrhizin ameliorates metabolic syndrome-induced liver damage in experimental rat model.
    Molecular and cellular biochemistry, 2015, Volume: 409, Issue:1-2

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Apoptosis; Aspartate Aminotransferases; Blood Glucose; DNA Damage; Fructose; Glutathione; Glycation End Products, Advanced; Glycyrrhizic Acid; Inflammation; Insulin; Liver; Liver Diseases; Male; Metabolic Syndrome; Mitochondria; NF-kappa B; Oxidative Stress; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reactive Oxygen Species; Triglycerides

2015
A case of pseudoaldosteronism, accompanied with hypocalcemia and exaggerated ACTH response.
    Endocrine journal, 2004, Volume: 51, Issue:1

    Topics: Adrenocorticotropic Hormone; Aged; Blood Pressure; Calcium; Corticotropin-Releasing Hormone; Female; Glycyrrhizic Acid; Humans; Hyperaldosteronism; Hypocalcemia; Liver Diseases; Potassium

2004
Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice.
    Journal of leukocyte biology, 2007, Volume: 81, Issue:1

    Topics: Active Transport, Cell Nucleus; Animals; Chemotaxis; Cytoplasm; Glycyrrhizic Acid; Hepatitis B virus; HMGB1 Protein; Inflammation; Liver Diseases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Necrosis; Neutrophils; RNA, Messenger; T-Lymphocytes, Cytotoxic

2007
Inhibitory effect of glycyrrhizin on lipopolysaccharide and d-galactosamine-induced mouse liver injury.
    European journal of pharmacology, 2007, Dec-08, Volume: 576, Issue:1-3

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cytokines; Galactosamine; Glycyrrhizic Acid; Lipopolysaccharides; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Protective Agents

2007
Glycyrrhizin attenuates endotoxin- induced acute liver injury after partial hepatectomy in rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2007, Volume: 40, Issue:12

    Topics: Acute Disease; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Apoptosis; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glycyrrhizic Acid; Hepatectomy; Immunohistochemistry; L-Lactate Dehydrogenase; Lipopolysaccharides; Liver Diseases; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Severity of Illness Index; Tumor Necrosis Factor-alpha

2007
Glycyrrhizin prevents of lipopolysaccharide/D-galactosamine-induced liver injury through down-regulation of matrix metalloproteinase-9 in mice.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:1

    Topics: Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Down-Regulation; Galactosamine; Glycyrrhizic Acid; Immunohistochemistry; Injections, Intraperitoneal; Injections, Intravenous; Lipopolysaccharides; Liver; Liver Diseases; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation

2008
[Mixed hypermineralocorticoidism: hepatopathy and glycyrrhizinic acid].
    Medicina clinica, 1983, Sep-17, Volume: 81, Issue:7

    Topics: Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Hyperaldosteronism; Liver Diseases

1983
Histopathologic and MRI findings in hypokalemic myopathy induced by glycyrrhizin.
    Acta neurologica Scandinavica, 1995, Volume: 92, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Hypokalemia; Liver Diseases; Magnetic Resonance Imaging; Male; Microscopy, Electron; Middle Aged; Muscle Weakness; Muscle, Skeletal; Phagocytosis; Potassium Chloride; Sarcolemma

1995
Effect of glycyrrhizin in children with liver dysfunction associated with cytomegalovirus infection.
    The Tohoku journal of experimental medicine, 1994, Volume: 172, Issue:2

    Topics: Antibodies, Viral; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Immunoglobulin G; Immunoglobulin M; Infant; Infusions, Intravenous; Liver Diseases

1994
Pharmacokinetics of glycyrrhizin in rats with D-galactosamine-induced hepatic disease.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:6

    Topics: Administration, Oral; Animals; Antiviral Agents; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Galactosamine; Gastric Emptying; Glycyrrhetinic Acid; Glycyrrhizic Acid; Injections, Intravenous; Intestinal Absorption; Liver Diseases; Male; Rats; Rats, Wistar

1996
Protective effect of celosian, an acidic polysaccharide, on chemically and immunologically induced liver injuries.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:4

    Topics: Animals; Bilirubin; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Enzymes; Galactosamine; Glycyrrhetinic Acid; Glycyrrhizic Acid; Lipid Peroxidation; Lipid Peroxides; Lipopolysaccharides; Liver; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Necrosis; Plant Extracts; Polysaccharides; Rats; Rats, Sprague-Dawley; Seeds; Tumor Necrosis Factor-alpha

1996
Potent antihepatotoxic activity of dicaffeoyl quinic acids from propolis.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:4

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cells, Cultured; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glycyrrhetinic Acid; Glycyrrhizic Acid; L-Lactate Dehydrogenase; Liver; Liver Diseases; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Propolis; Quinic Acid; Rats

1996
A cautionary note regarding glycyrrhiza (licorice root)
    The American journal of gastroenterology, 1999, Volume: 94, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Contraindications; Glycyrrhizic Acid; Humans; Hypertension, Portal; Liver Diseases

1999
The effects of pretreatment with glycyrrhizin and glycyrrhetinic acid on the retrorsine-induced hepatotoxicity in rats.
    Toxicon : official journal of the International Society on Toxinology, 1999, Volume: 37, Issue:9

    Topics: Administration, Topical; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Glutathione; Glycyrrhetinic Acid; Glycyrrhizic Acid; Liver; Liver Diseases; Male; Pyrrolizidine Alkaloids; Rats; Rats, Sprague-Dawley; Time Factors

1999
The protective effect of glycyrrhizin against injury of the liver caused by ischemia-reperfusion.
    Archives of environmental contamination and toxicology, 1991, Volume: 20, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Electron Spin Resonance Spectroscopy; Glutathione; Glycyrrhetinic Acid; Glycyrrhizic Acid; Ischemia; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Liver Diseases; Male; Rats; Rats, Inbred Strains; Reperfusion Injury; Superoxide Dismutase; Vitamin E

1991
Preparation of glycyrrhetic acid glycosides having various beta(1----2)-linked disaccharides and their cytoprotective effects on carbon tetrachloride-induced hepatic injury.
    Chemical & pharmaceutical bulletin, 1991, Volume: 39, Issue:9

    Topics: Animals; Carbohydrate Sequence; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disaccharides; Glycosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Liver Diseases; Molecular Sequence Data; Rats; Rats, Inbred Strains; Saponins

1991
Prediction of glycyrrhizin disposition in rat and man with liver failure by a physiologically based pharmacokinetic model.
    Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:2

    Topics: Animals; Antiviral Agents; Blood Proteins; Carbon Tetrachloride Poisoning; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hepatitis; Humans; Injections, Intravenous; Liver Diseases; Male; Models, Biological; Protein Binding; Rats; Rats, Inbred Strains; Tissue Distribution

1990