glycyrrhizic acid has been researched along with Innate Inflammatory Response in 88 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (2.27) | 18.2507 |
| 2000's | 5 (5.68) | 29.6817 |
| 2010's | 53 (60.23) | 24.3611 |
| 2020's | 28 (31.82) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Abed, Y; VanPatten, S | 1 |
| Guo, Q; Luo, R; Peng, X; Sun, Y; Wang, L; Wang, T; Wang, Y; Zou, M | 1 |
| Ishida, T; Jobu, K; Kawada, K; Kawazoe, T; Miyamura, M; Morisawa, S; Nishida, M; Nishimura, S; Tamura, N; Yoshioka, S | 1 |
| Athari, SS; Chen, L; Mehrabi Nasab, E | 1 |
| Irie, K; Iwaki, M; Kawase, A; Matsuda, N; Shimada, H; Takai, Y | 1 |
| Batu, W; Bi, W; Ren, C; Wang, J | 1 |
| Ahmed, KA; Amin, MM; El-Haddad, AE; El-Sadek, HM; El-Sayed, MK; Gendy, AM; Soubh, A | 1 |
| Ishida, T; Jobu, K; Kawada, K; Miyamura, M; Morisawa, S; Nishida, M; Tamura, N; Yoshioka, S | 1 |
| Cao, X; Hou, SZ; Li, Y; Zhang, M; Zhao, MC; Zhao, TQ | 1 |
| Andersson, U; Apostolopoulos, V; Gadanec, LK; Zulli, A | 1 |
| Bianchi, ME; Casalgrandi, M; De Leo, F; De Marchis, F; Gori, A; Mannella, V; Mezzapelle, R; Musco, G; Preti, A; Quilici, G; Tirone, M; Zucchelli, C | 1 |
| Dong, S; Huang, H; Liu, C; Sha, H; Wei, W; Yu, M | 1 |
| Deghidy, EA; El-Deeb, OS; El-Esawy, RO; Mohamed, DA; Shafik, NM | 1 |
| Jiang, Y; Liu, L; Steinle, JJ | 1 |
| Chattopadhyay, M; Sadanandan, J; Thakur, V | 1 |
| Bi, XY; Cao, ZY; Jiang, CL; Li, JM; Liu, LL; Liu, YZ; Ruan, YM; Su, WJ; Wang, B; Wang, W; Wang, YX; Wu, R; Yan, WJ; Zhang, T; Zhong, SY | 1 |
| Chen, L; Du, J; Hood, M; Hu, C; Kan, J; Zhang, L; Zhang, X | 1 |
| Chen, Q; Gong, Z; Jiao, F; Lv, J; Pei, M; Shi, C; Wang, L; Wang, Y; Zhang, H | 1 |
| Barone, A; Celia, C; Cilurzo, F; Cristiano, MC; Di Marzio, L; Iannotta, D; Locatelli, M; Paolino, D | 1 |
| Li, JH; Li, RD; Ma, ZY; Shen, CH; Tao, YF; Wang, ZX; Zhang, QB | 1 |
| Al-Gayyar, MM; El-Sherbiny, M; Elsherbini, AM; Elsherbiny, NM; Maysarah, NM | 1 |
| Chea, C; Furusho, H; Iwasaki, S; Miyauchi, M; Nishihara, T; Ohta, K; Shiba, F; Shimizu, R; Takata, T | 1 |
| El Fayoumi, HM; Emara, NA; Mahmoud, AAA; Mahmoud, MF | 1 |
| Cui, YL; Wang, GF; Wang, QS; Xu, D; Zhang, HY; Zhao, FQ | 1 |
| Richard, SA | 1 |
| Lan, T; Li, C; Li, L | 1 |
| Ahmad, A; Alam, P; Ansari, MM; Jayamurugan, G; Khan, R; Khan, TH; Kumar, A; Raza, SS | 1 |
| Bian, Y; Li, J; Luo, Y; Wang, B; Wang, R; Zhang, Q | 1 |
| Hiramoto, K; Kawanishi, S; Ma, N; Murata, M; Ohnishi, S; Wang, G; Yoshikawa, N | 1 |
| Huang, X; Jiang, G; Li, B; Liu, Y; Shan, H; Tan, Q; Tang, L; Wang, W; Xiao, Y; Xu, L; Zhao, Z; Zhou, H; Zhu, T | 1 |
| Cheng, X; Fan, M; Liu, S; Liu, Z; Lu, E; Pi, Z; Song, F; Zheng, Z | 1 |
| Acharya, K; Belén, LH; Beyatli, A; Cruz-Martins, N; Herrera-Bravo, J; Kamal, RM; Kaur, R; Kırkın, C; Kregiel, D; Kumar, M; Özçelik, B; Quispe, C; Razis, AFA; Sen, S; Shaheen, S; Sharifi-Rad, J; Sharopov, F; Suleria, HAR; Sunusi, U; Uprety, Y; Yeskaliyeva, B | 1 |
| Fan, C; Han, C; He, X; Jin, T; Li, C; Liu, S; Liu, X; Peng, S; Shan, L; Shan, Z; Teng, W; Wang, W; Wang, X; Xie, X; Zhang, H | 1 |
| Chu, L; Hao, HG; Wang, XR | 1 |
| Ieong, C; Ma, J; Sun, H; Wang, Q | 1 |
| Abo El-Magd, NF; El-Karef, A; El-Mesery, M; El-Shishtawy, MM | 1 |
| Chen, J; Li, W; Shi, M; Zhang, H; Zhang, R; Zhang, X | 1 |
| Deng, P; Feng, Y; Sun, X; Wang, Q; Wu, J; Yu, Q; Zeng, H; Zhang, H | 1 |
| Chen, J; Chen, X; Liang, C; Sun, W; Xu, C | 1 |
| Cao, L; Gonzalez, FJ; Hao, H; Krausz, KW; Li, G; Takahashi, S; Wang, G; Wang, H; Wang, Q; Yagai, T; Yan, T | 1 |
| Abrahams, VM; Guller, S; Han, CS; Heim, KR; Mulla, MJ; Potter, JA | 1 |
| Khan, AQ; Khan, R; Rehman, MU; Sultana, S; Tahir, M | 1 |
| Biguetti, CC; Campanelli, AP; Cavalla, F; Francisconi, CF; Garlet, GP; Rodrigues, DC; Silveira, EV; Tabanez, AP; Taga, R; Trombone, APF | 1 |
| Cesi, V; Colantoni, E; Cucchiara, S; Isoldi, S; Mancuso, AB; Negroni, A; Palone, F; Stronati, L; Vitali, R | 1 |
| Deye, S; Jiangdong, N; Jun, H; Junjie, W; Mingming, Y; Muliang, D; Wenzhao, L; Xianzhe, H | 1 |
| Gao, Q; Shi, HJ; Si, JW; Song, HB; Zou, Q | 1 |
| Cao, Z; Liu, Y; Ni, B | 1 |
| Efferth, T; Fu, Y; Luo, M; Wang, S; Wang, W; Zu, Y | 1 |
| Kuo, HC; Lee, KF; Tsai, JJ; Tsai, TH | 1 |
| Aloi, M; Cavone, L; Costanzo, M; Cucchiara, S; Dilillo, A; Negroni, A; Palone, F; Stronati, L; Vitali, R | 1 |
| Cai, L; Dong, H; Gong, G; Hu, L; Wu, W; Xiang, L; Yin, L; Yuan, L | 1 |
| Abu El-Asrar, AM; Geboes, K; Mohammad, G; Nawaz, MI; Siddiquei, MM | 1 |
| Corsini, E; Galbiati, V; Galli, CL; Marinovich, M; Papale, A | 1 |
| Fujii, I; Hayashi, H; Hirai, Y; Honda, H; Ikutani, M; Matsunaga, T; Muraguchi, A; Nagai, Y; Okamoto, N; Takatsu, K; Tsuneyama, K; Watanabe, Y | 1 |
| Cui, Z; Lin, Y; Shen, L; Tan, Q; Wang, S; Zheng, D | 1 |
| Guo, H; He, LX; Liu, Q; Sun, H; Tian, XX; Wu, CX | 1 |
| Hu, X; Huang, J; Tang, Y; Wang, Q; Wu, Q; Zhang, J | 1 |
| Cao, W; Chen, W; Dong, X; Gao, Y; Hua, W; Qi, J; Wang, J; Wu, H; Wu, T; Yang, Q; Zhao, X; Zhou, J | 1 |
| Guo, Q; Han, Y; Tan, G; Tang, Z; Xiong, H; Xu, W; Xu, Y; Zeng, F | 1 |
| Chen, Y; Li, PL; Li, X; Pitzer, AL; Wang, L; Zhang, Y | 1 |
| Chang, CZ; Kwan, AL; Wu, SC | 1 |
| Li, YX; Ma, L; Niu, Y; Niu, YT; Shi, GJ; Sun, T; Wang, HL; Wu, J; Yu, JQ; Zheng, J | 1 |
| Ha, JY; Jung, JC; Jung, YS; Kim, KM; Oh, S; Yu, JY | 1 |
| Chakraborti, AS; Ray, D; Sil, R | 1 |
| Chen, JX; Chen, XX; Li, YL; Ma, YJ; Ning, ZY; Qi, WB; Wang, GC; Zhou, HX | 1 |
| Jin, S; Liu, Z; Shen, H; Zhang, S; Zhao, H | 1 |
| Li, S; Liu, J; Sun, CL; Wang, J; Wang, JF; Zhang, BL | 1 |
| Duan, X; Liu, K; Liu, Z; Meng, Q; Sun, H; Sun, P; Sun, X; Wang, C; Yang, X | 1 |
| González-Reyes, S; Guevara-Guzmán, R; Jiménez-Osorio, AS; Pedraza-Chaverri, J; Santillán-Cigales, JJ | 1 |
| Asano, Y; Ichimura, Y; Miura, S; Nakamura, K; Saigusa, R; Sato, S; Takahashi, T; Taniguchi, T; Toyama, T; Trojanowska, M; Yamashita, T; Yoshizaki, A | 1 |
| Chen, QJ; Guan, XF; Guo, R; Li, DY; Peng, XD; Wang, JL; Yin, WJ; Zuo, XC | 1 |
| Huan, CC; Mao, X; Sheng, XX; Wang, HX; Wang, R; Wang, X | 1 |
| Crisafulli, C; Cuzzocrea, S; Dal Bosco, M; Di Paola, R; Genovese, T; Mazzon, E; Menegazzi, M; Suzuki, H; Zou, Z | 1 |
| Chen, JQ; Jiang, RA; Mao, LG; Qian, Y; Shi, JR; Tang, HF | 1 |
| Kao, TC; Shyu, MH; Yen, GC | 1 |
| Ha, H; Jung, D; Lee, HY; Lee, JA; Lee, JK; Lee, MY; Seo, CS; Shin, HK | 1 |
| Cinatl, J; Doerr, HW; Geiler, J; Leutz, A; Michaelis, M; Naczk, P; Sithisarn, P | 1 |
| Kao, TC; Lo, WH; Wang, CY; Yen, GC | 1 |
| Hou, SZ; Li, Y; Wang, X; Wang, ZY; Xu, Y; Zhu, XL | 1 |
| Cichoń, T; Jarosz, M; Kamysz, W; Kobusińska, M; Lesiak, M; Matuszczak, S; Mitrus, I; Sieroń, A; Smolarczyk, R; Szala, S | 1 |
| Akashi, T; Azuma, T; Inoue, J; Ishida, T; Kawauchi, S; Kondo, Y; Miki, I; Mizuno, S; Nishiumi, S; Tanahashi, T; Yamasaki, A; Yamazaki, A; Yoshida, M | 1 |
| Jin, JL; Li, H; Qian, L; Wang, SL; Xu, Y; Zhao, H; Zhu, XL | 1 |
| Fujiyama, S; Hirokawa, S; Masaki, T; Miyakawa, K; Ohkawa, S; Tamai, S; Tanaka, K; Tarao, K | 1 |
| Alhaique, F; Fresta, M; Lucania, G; Mardente, D; Paolino, D | 1 |
| Bianchi, ME; Guidotti, LG; Iannacone, M; Müller, S; Sitia, G | 1 |
| Girard, JP | 1 |
| Anderson, MB; Bochner, BS; Brandley, BK; Kim, MK | 1 |
| Schleimer, RP | 1 |
3 review(s) available for glycyrrhizic acid and Innate Inflammatory Response
| Article | Year |
|---|---|
High Mobility Group Box-1 (HMGb1): Current Wisdom and Advancement as a Potential Drug Target.
Topics: Alarmins; Biomarkers; HMGB1 Protein; Humans; Immunity, Innate; Inflammation; Molecular Targeted Therapy; Pathogen-Associated Molecular Pattern Molecules | 2018 |
Exploring the Pivotal Immunomodulatory and Anti-Inflammatory Potentials of Glycyrrhizic and Glycyrrhetinic Acids.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Drugs, Chinese Herbal; Glycyrrhetinic Acid; Glycyrrhiza; Glycyrrhizic Acid; Humans; Immunologic Factors; Inflammation; Interferons; Interleukins; Leishmania; Macrophages; MAP Kinase Signaling System; Nitric Oxide; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Th1 Cells; Toll-Like Receptors | 2021 |
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Glycyrrhiza; Glycyrrhizic Acid; Humans; Immunologic Deficiency Syndromes; Inflammation; Phytochemicals | 2021 |
2 trial(s) available for glycyrrhizic acid and Innate Inflammatory Response
| Article | Year |
|---|---|
Glycyrrhizic acid as an adjunctive treatment for depression through anti-inflammation: A randomized placebo-controlled clinical trial.
Topics: Anti-Inflammatory Agents; Antidepressive Agents; Depression; Double-Blind Method; Glycyrrhizic Acid; Humans; Inflammation; Treatment Outcome | 2020 |
Ethosomes for skin delivery of ammonium glycyrrhizinate: in vitro percutaneous permeation through human skin and in vivo anti-inflammatory activity on human volunteers.
Topics: Administration, Topical; Anti-Inflammatory Agents; Delayed-Action Preparations; Epidermis; Erythema; Ethanol; Glycyrrhizic Acid; Humans; In Vitro Techniques; Inflammation; Liposomes; Nicotinic Acids; Permeability; Phospholipids; Skin Absorption; Water | 2005 |
83 other study(ies) available for glycyrrhizic acid and Innate Inflammatory Response
| Article | Year |
|---|---|
Glycyrrhizic Acid against
Topics: Animals; Apoptosis; Chickens; Glycyrrhizic Acid; Inflammation; Mycoplasma gallisepticum; Poultry Diseases | 2022 |
Yokukansan suppresses neuroinflammation in the hippocampus of mice and decreases the duration of lipopolysaccharide- and diazepam-mediated loss of righting reflex induced by pentobarbital.
Topics: Animals; Delirium; Diazepam; Drugs, Chinese Herbal; Glycyrrhizic Acid; Hippocampus; Inflammation; Interleukin-6; Lipopolysaccharides; Mice; Neuroinflammatory Diseases; NF-kappa B; Pentobarbital; Reflex, Righting; Tumor Necrosis Factor-alpha | 2022 |
Effect of Loaded Glycyrrhizic Acid on PLGA Nano-particle on Treatment of Allergic Asthma.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Disease Models, Animal; Glycyrrhizic Acid; Humans; Hypersensitivity; Inflammation | 2022 |
Distinct roles of HMGB1 in the regulation of P‑glycoprotein expression in the liver and kidney of mice with lipopolysaccharide‑induced inflammation.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, Liquid; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Kidney; Lipopolysaccharides; Liver; Mice; Receptor for Advanced Glycation End Products; RNA, Messenger; Signal Transduction; Tandem Mass Spectrometry; Toll-Like Receptor 4 | 2022 |
Glycyrrhizin mitigates acute lung injury by inhibiting the NLRP3 inflammasome in vitro and in vivo.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Cytokines; Glycyrrhizic Acid; Inflammasomes; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein | 2023 |
Glycyrrhizin prevents 3-nitropropionic acid-induced neurotoxicity by downregulating HMGB1/TLR4/NF-κB p65 signaling, and attenuating oxidative stress, inflammation, and apoptosis in rats.
Topics: Animals; Apoptosis; Body Weight; Glycyrrhizic Acid; HMGB1 Protein; Huntington Disease; Inflammation; NF-kappa B; Oxidative Stress; Rats; Toll-Like Receptor 4 | 2023 |
Glycyrrhizae Radix suppresses lipopolysaccharide- and diazepam-induced nerve inflammation in the hippocampus, and contracts the duration of pentobarbital- induced loss of righting reflex in a mouse model.
Topics: Animals; Diazepam; Drugs, Chinese Herbal; Glycyrrhiza; Glycyrrhizic Acid; Hippocampus; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mice; Pentobarbital; Plant Extracts; Reflex, Righting | 2023 |
Glycyrrhizic Acid Protects Glomerular Podocytes Induced by High Glucose by Modulating SNARK/AMPK Signaling Pathway.
Topics: AMP-Activated Protein Kinases; Diabetic Nephropathies; Fibrosis; Glucose; Glycyrrhizic Acid; Humans; Inflammation; Podocytes; RNA, Small Interfering; Signal Transduction | 2023 |
Glycyrrhizic Acid Inhibits High-Mobility Group Box-1 and Homocysteine-Induced Vascular Dysfunction.
Topics: Acetylcholine; Animals; Atherosclerosis; Glycyrrhizic Acid; HMGB Proteins; Homocysteine; Hyperhomocysteinemia; Inflammation; Male; Rabbits | 2023 |
Diflunisal targets the HMGB1/CXCL12 heterocomplex and blocks immune cell recruitment.
Topics: 3T3 Cells; Animals; Chemokine CXCL12; Chemotaxis; Diflunisal; Disulfides; Glycyrrhizic Acid; HMGB1 Protein; Humans; Inflammation; Leukocytes; Macrophages; Magnetic Resonance Spectroscopy; Mice | 2019 |
High mobility group box-1 mediates hippocampal inflammation and contributes to cognitive deficits in high-fat high-fructose diet-induced obese rats.
Topics: Animals; Apoptosis; Cognition; Cognitive Dysfunction; Diet, High-Fat; Glycyrrhizic Acid; Hippocampus; HMGB Proteins; HMGB1 Protein; Inflammation; Interleukin-1beta; Interleukin-6; Male; Microglia; NF-kappa B; Obesity; Rats; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2019 |
Regenerative effects of glycyrrhizin and/or platelet rich plasma on type-II collagen induced arthritis: Targeting autophay machinery markers, inflammation and oxidative stress.
Topics: Animals; Arthritis, Experimental; Autophagy; Beclin-1; Biomarkers; Collagen Type II; Female; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Male; NF-E2-Related Factor 2; Oxidative Stress; Platelet-Rich Plasma; Rats; Rats, Wistar | 2019 |
Glycyrrhizin protects IGFBP-3 knockout mice from retinal damage.
Topics: Animals; Anti-Inflammatory Agents; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Insulin-Like Growth Factor Binding Protein 3; Interleukin-1beta; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Reactive Oxygen Species; Retina; Retinal Ganglion Cells; Sirtuin 1; Tumor Necrosis Factor-alpha | 2020 |
High-Mobility Group Box 1 Protein Signaling in Painful Diabetic Neuropathy.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glycyrrhizic Acid; HMGB1 Protein; Humans; Inflammation; Male; Mice; Microglia; Neurons; Pain; Peripheral Nervous System Diseases; Quality of Life; Rats; Receptor for Advanced Glycation End Products; Signal Transduction | 2020 |
A Novel Combination of Vitamin C, Curcumin and Glycyrrhizic Acid Potentially Regulates Immune and Inflammatory Response Associated with Coronavirus Infections: A Perspective from System Biology Analysis.
Topics: Anti-Inflammatory Agents; Ascorbic Acid; Coronavirus; Coronavirus Infections; Curcuma; Curcumin; Cytokines; Drug Combinations; Drug Delivery Systems; Gene Ontology; Glycyrrhiza; Glycyrrhizic Acid; Humans; Immunity, Innate; Inflammation; Interferons; Plant Extracts; Signal Transduction; Systems Biology; T-Lymphocytes; Vitamins | 2020 |
TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury.
Topics: Acute Kidney Injury; Animals; Cell Differentiation; Glycyrrhizic Acid; HMGB1 Protein; Humans; Inflammation; Lenalidomide; Liver Failure, Acute; Macrophages; Male; Mice, Inbred C57BL; Polymorphism, Single Nucleotide; Pyroptosis; Signal Transduction; THP-1 Cells; Tumor Necrosis Factor-alpha | 2020 |
Ammonium glycyrrhizate skin delivery from ultradeformable liposomes: A novel use as an anti-inflammatory agent in topical drug delivery.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Drug Delivery Systems; Erythema; Glycyrrhiza; Glycyrrhizic Acid; Healthy Volunteers; Humans; Inflammation; Liposomes; Nicotinic Acids; Particle Size; Skin; Surface Properties | 2020 |
Glycyrrhizin improves inflammation and apoptosis via suppressing HMGB1 and PI3K/mTOR pathway in lipopolysaccharide-induced acute liver injury.
Topics: Administration, Oral; Animals; Apoptosis; Cells, Cultured; Chemical and Drug Induced Liver Injury; Glycyrrhizic Acid; HMGB1 Protein; Humans; Inflammation; Injections, Intraperitoneal; Lipopolysaccharides; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; TOR Serine-Threonine Kinases | 2020 |
Glycyrrhizic acid ameliorates sodium nitrite-induced lung and salivary gland toxicity: Impact on oxidative stress, inflammation and fibrosis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Fibrosis; Glutathione; Glycyrrhizic Acid; Inflammation; Lung; Male; Malondialdehyde; Oxidative Stress; Rats, Sprague-Dawley; Salivary Glands; Sodium Nitrite | 2021 |
Anti-inflammatory effect of glycyrrhizin with Equisetum arvense extract.
Topics: Animals; Anti-Inflammatory Agents; Equisetum; Glycyrrhizic Acid; Inflammation; Lipopolysaccharides; NF-kappa B; Plant Extracts; Rats | 2021 |
The renoprotective effect of glycyrrhizic acid in insulin-resistant rats exposed to aluminum involves the inhibition of TLR4/NF-κB signaling pathway.
Topics: Aluminum Chloride; Animals; Disease Models, Animal; Fructose; Glycyrrhizic Acid; Inflammation; Insulin Resistance; Kidney Diseases; Male; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Signal Transduction; Toll-Like Receptor 4 | 2021 |
Glycyrrhizin mediated liver-targeted alginate nanogels delivers quercetin to relieve acute liver failure.
Topics: Alanine Transaminase; Alginates; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; China; Glycyrrhizic Acid; Inflammation; Liver; Liver Failure, Acute; Male; Mice; Nanogels; Nitric Oxide Synthase Type II; Oxidative Stress; Quercetin; Tumor Necrosis Factor-alpha | 2021 |
Co-treatment with disulfiram and glycyrrhizic acid suppresses the inflammatory response of chondrocytes.
Topics: Cell Proliferation; Cells, Cultured; Chondrocytes; Disulfiram; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Humans; Inflammation; Osteoarthritis; Phytotherapy; Pyroptosis | 2021 |
Aminocellulose-grafted-polycaprolactone coated gelatin nanoparticles alleviate inflammation in rheumatoid arthritis: A combinational therapeutic approach.
Topics: Animals; Arthritis, Rheumatoid; Biomarkers; Bone and Bones; Budesonide; Cartilage; Cellulose; Collagen; Cyclooxygenase 2; Drug Delivery Systems; Female; Fibroblasts; Gelatin; Glycyrrhizic Acid; Humans; Inflammation; Interleukin-1beta; Kinetics; Magnetic Resonance Spectroscopy; Nanoparticles; Nitric Oxide Synthase Type II; Polyesters; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2021 |
Protective effect of glycyrrhizin on osteoarthritis cartilage degeneration and inflammation response in a rat model.
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Glycyrrhizic Acid; Inflammation; Male; Osteoarthritis; Rats; Rats, Wistar | 2021 |
Glycyrrhizin Attenuates Carcinogenesis by Inhibiting the Inflammatory Response in a Murine Model of Colorectal Cancer.
Topics: Animals; Azoxymethane; Carcinogenesis; Colon; Colorectal Neoplasms; Disease Models, Animal; Female; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Interleukin-6; Mice; Mice, Inbred ICR; NF-kappa B; Signal Transduction; Tumor Necrosis Factor-alpha | 2021 |
Glycyrrhizic Acid Nanoparticles as Antiviral and Anti-inflammatory Agents for COVID-19 Treatment.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Antiviral Agents; Coronavirus Nucleocapsid Proteins; COVID-19 Drug Treatment; Cytokines; Female; Glycyrrhizic Acid; Humans; Inflammation; Liver; Lung; Mice; Mice, Inbred BALB C; Murine hepatitis virus; Nanoparticles; Phosphoproteins; RAW 264.7 Cells; SARS-CoV-2; THP-1 Cells; Viral Load; Virus Diseases; Virus Replication | 2021 |
A comprehensive strategy to clarify the pharmacodynamic constituents and mechanism of Wu-tou decoction based on the constituents migrating to blood and their in vivo process under pathological state.
Topics: Administration, Oral; Animals; Antirheumatic Agents; Arthritis, Experimental; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Disease Models, Animal; Drugs, Chinese Herbal; Glycyrrhizic Acid; Inflammation; Lipopolysaccharides; Male; Mass Spectrometry; Medicine, Chinese Traditional; Metabolic Networks and Pathways; Mice; Rats, Sprague-Dawley; RAW 264.7 Cells; Tissue Distribution; Tumor Necrosis Factor-alpha | 2021 |
Glycyrrhizin, a Direct HMGB1 Antagonist, Ameliorates Inflammatory Infiltration in a Model of Autoimmune Thyroiditis via Inhibition of TLR2-HMGB1 Signaling.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Male; Mice; Myeloid Differentiation Factor 88; Signal Transduction; Sodium Iodide; T-Lymphocytes, Regulatory; Thyroid Gland; Thyroiditis, Autoimmune; Toll-Like Receptor 2 | 2017 |
Glycyrrhizin inhibits LPS-induced inflammatory mediator production in endometrial epithelial cells.
Topics: Animals; Anti-Inflammatory Agents; Cell Culture Techniques; Cell Line; Cell Survival; Cyclooxygenase 2; Cytokines; Dinoprostone; Endometriosis; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Female; Glycyrrhiza; Glycyrrhizic Acid; Inflammation; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Plant Roots; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2017 |
Glycyrrhizin suppresses the expressions of HMGB1 and ameliorates inflammative effect after acute subarachnoid hemorrhage in rat model.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Blood-Brain Barrier; Blotting, Western; Brain; Glycyrrhizic Acid; HMGB1 Protein; In Situ Nick-End Labeling; Inflammation; Male; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage | 2018 |
Glycyrrhizin ameliorates high fat diet-induced obesity in rats by activating NrF2 pathway.
Topics: Adipocytes; Adipose Tissue; Animals; Diet, High-Fat; Glycyrrhizic Acid; Inflammation; Insulin; Insulin Resistance; Liver; Male; NF-E2-Related Factor 2; Obesity; Oxidative Stress; Rats; Rats, Wistar; Receptor, Insulin | 2018 |
High Mobility Group Box1 Inhibitor Glycyrrhizic Acid Attenuates Kidney Injury in Streptozotocin-Induced Diabetic Rats.
Topics: Animals; Diabetes Mellitus, Experimental; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Kidney; MAP Kinase Signaling System; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Rats; Receptor for Advanced Glycation End Products; Streptozocin; Toll-Like Receptor 4 | 2017 |
Glycyrrhizin ameliorates inflammatory pain by inhibiting microglial activation-mediated inflammatory response via blockage of the HMGB1-TLR4-NF-kB pathway.
Topics: Animals; Cells, Cultured; Glycyrrhizic Acid; HEK293 Cells; HMGB1 Protein; Hot Temperature; Humans; Hyperalgesia; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; NF-kappa B; Pain; Signal Transduction; Toll-Like Receptor 4 | 2018 |
Glycyrrhizic acid ameliorates myocardial ischemic injury by the regulation of inflammation and oxidative state.
Topics: Animals; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Inflammation; Injections, Intraperitoneal; Male; Myocardial Ischemia; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Glycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-Inflammation.
Topics: Animals; Anti-Inflammatory Agents; Bile Acids and Salts; Glycyrrhizic Acid; Hep G2 Cells; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Random Allocation; RAW 264.7 Cells | 2018 |
Excess glucose induce trophoblast inflammation and limit cell migration through HMGB1 activation of Toll-Like receptor 4.
Topics: Alarmins; Cell Line; Cell Movement; Female; Glycyrrhizic Acid; HMGB1 Protein; Humans; Hyperglycemia; Inflammation; Interleukin-1beta; Interleukin-8; Pre-Eclampsia; Pregnancy; Risk; Signal Transduction; Toll-Like Receptor 4; Trophoblasts; Vascular Endothelial Growth Factor Receptor-1 | 2018 |
Glycyrrhizic acid suppresses 1,2-dimethylhydrazine-induced colon tumorigenesis in Wistar rats: Alleviation of inflammatory, proliferation, angiogenic, and apoptotic markers.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Apoptosis; Biomarkers; Carcinogenesis; Cell Proliferation; Colonic Neoplasms; Glycyrrhizic Acid; Inflammation; Male; Neovascularization, Physiologic; Rats; Rats, Wistar | 2018 |
HGMB1 and RAGE as Essential Components of Ti Osseointegration Process in Mice.
Topics: Animals; Antigens, Neoplasm; Arthroplasty; Biocompatible Materials; Biomarkers; Bone Matrix; Cell Movement; Glycyrrhizic Acid; HMGB Proteins; Humans; Immunomodulation; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Osseointegration; Peptides; Titanium | 2019 |
Dipotassium Glycyrrhizate Improves Intestinal Mucosal Healing by Modulating Extracellular Matrix Remodeling Genes and Restoring Epithelial Barrier Functions.
Topics: Animals; Caco-2 Cells; Cell Line; Cell Line, Tumor; Colitis; Cytokines; Epithelial Cells; Extracellular Matrix; Female; Glycyrrhizic Acid; HMGB1 Protein; HT29 Cells; Humans; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Wound Healing | 2019 |
Dual regulatory roles of HMGB1 in inflammatory reaction of chondrocyte cells and mice.
Topics: Animals; Apoptosis; Autophagy; Cells, Cultured; Chondrocytes; Cytosol; Disease Models, Animal; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Iodoacetic Acid; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Osteoarthritis; Time Factors; Transfection | 2019 |
Combination of oxymatrine and diammonium glycyrrhizinate significantly mitigates mice allergic contact dermatitis induced by dinitrofluorobenzene.
Topics: Alkaloids; Animals; Creatinine; Dermatitis, Allergic Contact; Dinitrofluorobenzene; Drug Therapy, Combination; Ear; Glycyrrhizic Acid; Immunoglobulin E; Inflammation; Interferon-gamma; Interleukin-4; Male; Mice, Inbred BALB C; Mice, Inbred ICR; Potassium; Quinolizines; Skin; Sodium; Urea | 2019 |
Glycyrrhizin protects spinal cord and reduces inflammation in spinal cord ischemia-reperfusion injury.
Topics: Animals; Glycyrrhizic Acid; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; NF-kappa B; Reperfusion Injury; Spinal Cord Ischemia; Tumor Necrosis Factor-alpha | 2013 |
Glycyrrhizic acid nanoparticles inhibit LPS-induced inflammatory mediators in 264.7 mouse macrophages compared with unprocessed glycyrrhizic acid.
Topics: Animals; Cell Survival; Drug Carriers; Glycyrrhizic Acid; Inflammation; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Nanoparticles; Nitric Oxide; Surface Properties; Tumor Necrosis Factor-alpha | 2013 |
Glycyrrhizin represses total parenteral nutrition-associated acute liver injury in rats by suppressing endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Bilirubin; Caspase 3; Cytokines; Endoplasmic Reticulum Stress; Glycyrrhizic Acid; Immunohistochemistry; Inflammation; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Liver; Liver Diseases; Male; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Parenteral Nutrition, Total; Phosphorylation; Rats, Sprague-Dawley; Reactive Nitrogen Species; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Transcription Factor CHOP; Triglycerides; Tyrosine | 2013 |
Dipotassium Glycyrrhizate Inhibits HMGB1-Dependent Inflammation and Ameliorates Colitis in Mice.
Topics: Animals; Cell Line; Cell Line, Tumor; Colitis; Cytokines; Female; Glycyrrhizic Acid; HMGB1 Protein; Humans; Inflammation; Inflammation Mediators; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction | 2013 |
Protective effect of glycyrrhizin, a direct HMGB1 inhibitor, on focal cerebral ischemia/reperfusion-induced inflammation, oxidative stress, and apoptosis in rats.
Topics: Animals; Antioxidants; Apoptosis; Brain Ischemia; Cerebral Infarction; Glycyrrhizic Acid; HMGB1 Protein; Infarction, Middle Cerebral Artery; Inflammation; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Rats, Sprague-Dawley; Reperfusion Injury | 2014 |
The proinflammatory cytokine high-mobility group box-1 mediates retinal neuropathy induced by diabetes.
Topics: Animals; Cytokines; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glutamate-Ammonia Ligase; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Lactoylglutathione Lyase; Male; Rats; Rats, Sprague-Dawley; Retina; Synaptophysin; Tyrosine 3-Monooxygenase | 2014 |
Role of ROS and HMGB1 in contact allergen-induced IL-18 production in human keratinocytes.
Topics: Acyclic Monoterpenes; Allergens; Caspase 1; Cell Line; Cell Survival; Cytokines; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Epidermis; Glycyrrhizic Acid; HMGB1 Protein; Humans; Inflammation; Interleukin-18; Keratinocytes; Monoterpenes; Onium Compounds; Phenylenediamines; Reactive Oxygen Species; Toll-Like Receptor 4 | 2014 |
Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome activation and diet-induced adipose tissue inflammation.
Topics: Adipose Tissue, White; Animals; Anti-Inflammatory Agents; Carrier Proteins; Cell Line, Tumor; Chalcones; Diet, High-Fat; DNA-Binding Proteins; Glyburide; Glycyrrhiza uralensis; Glycyrrhizic Acid; Humans; Hypercholesterolemia; Inflammasomes; Inflammation; Insulin Resistance; Interleukin-1beta; Islet Amyloid Polypeptide; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Obesity; Specific Pathogen-Free Organisms | 2014 |
Anti-inflammative effect of glycyrrhizin on rat thermal injury via inhibition of high-mobility group box 1 protein.
Topics: Actins; Animals; Anti-Inflammatory Agents; Blotting, Western; Burns; Disease Models, Animal; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Injections, Intraperitoneal; Interleukin-1beta; Kidney; Liver; Lung; Male; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2015 |
Inhibition effect of glycyrrhizin in lipopolysaccharide-induced high-mobility group box 1 releasing and expression from RAW264.7 cells.
Topics: Animals; Anti-Inflammatory Agents; Cell Nucleus; Cytoplasm; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Interleukin-6; Lipopolysaccharides; Mice; Microscopy, Fluorescence; p38 Mitogen-Activated Protein Kinases; RAW 264.7 Cells; Sepsis; Signal Transduction; Tumor Necrosis Factor-alpha | 2015 |
[Therapeutic effects of glycyrrhizic acid on asthma airway inflammation in mice and its mechanism].
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Eosinophils; Female; Glycyrrhizic Acid; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-4; Mice; Mice, Inbred BALB C; Ovalbumin | 2014 |
PGE2 receptor agonist misoprostol protects brain against intracerebral hemorrhage in mice.
Topics: Animals; Cerebral Hemorrhage; Disease Models, Animal; Fibroblast Growth Factor 1; Gene Expression; Glycyrrhizic Acid; Inflammation; Interleukin-1beta; Male; Matrix Metalloproteinase 2; Mice, Inbred C57BL; Misoprostol; Neuroprotective Agents; Receptors, Prostaglandin E; src-Family Kinases | 2015 |
Glycyrrhizin ameliorates imiquimod-induced psoriasis-like skin lesions in BALB/c mice and inhibits TNF-α-induced ICAM-1 expression via NF-κB/MAPK in HaCaT cells.
Topics: Aminoquinolines; Animals; Cell Adhesion; Cell Line; Cell Survival; Female; Glycyrrhizic Acid; Humans; Imiquimod; Inflammation; Intercellular Adhesion Molecule-1; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Phosphorylation; Psoriasis; Signal Transduction; Skin Diseases; Tumor Necrosis Factor-alpha; Up-Regulation | 2015 |
Coronary endothelial dysfunction induced by nucleotide oligomerization domain-like receptor protein with pyrin domain containing 3 inflammasome activation during hypercholesterolemia: beyond inflammation.
Topics: Acetylcholine; Animals; Bradykinin; Carrier Proteins; Caspase 1; Cholesterol; Coronary Vessels; Cytoskeletal Proteins; Disease Models, Animal; Endothelial Cells; Glycyrrhizic Acid; HMGB1 Protein; Hypercholesterolemia; Inflammasomes; Inflammation; Male; Mice, Inbred C57BL; Nitric Oxide; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleotides; Poloxamer; Pyrin; Pyroptosis; Reactive Oxygen Species; Receptors, Cell Surface; Serpins; Superoxides; Vasodilation; Viral Proteins | 2015 |
Glycyrrhizin Attenuates Proinflammatory Cytokines through a Peroxisome Proliferator-Activated Receptor-γ-Dependent Mechanism and Experimental Vasospasm in a Rat Model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Basilar Artery; Cytokines; Drugs, Chinese Herbal; Endothelium, Vascular; Gene Expression Regulation; Glycyrrhizic Acid; Inflammation; Infusion Pumps; Male; Phytotherapy; PPAR delta; PPAR gamma; Premedication; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Single-Blind Method; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2015 |
Observing Anti-inflammatory and Anti-nociceptive Activities of Glycyrrhizin Through Regulating COX-2 and Pro-inflammatory Cytokines Expressions in Mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Formaldehyde; Glycyrrhizic Acid; Indomethacin; Inflammation; Inflammation Mediators; Male; Mice, Inbred ICR; Motor Activity; Nitric Oxide Synthase Type II; Nociceptive Pain; Pain Threshold; Psychomotor Performance; Time Factors; Xylenes | 2015 |
Anti-Inflammatory activities of licorice extract and its active compounds, glycyrrhizic acid, liquiritin and liquiritigenin, in BV2 cells and mice liver.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line; Disease Models, Animal; Flavanones; Glucosides; Glycyrrhiza; Glycyrrhizic Acid; Inflammation; Inflammation Mediators; Liver; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Oxidative Stress; Plant Extracts; Tumor Necrosis Factor-alpha | 2015 |
Glycyrrhizin ameliorates metabolic syndrome-induced liver damage in experimental rat model.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Apoptosis; Aspartate Aminotransferases; Blood Glucose; DNA Damage; Fructose; Glutathione; Glycation End Products, Advanced; Glycyrrhizic Acid; Inflammation; Insulin; Liver; Liver Diseases; Male; Metabolic Syndrome; Mitochondria; NF-kappa B; Oxidative Stress; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reactive Oxygen Species; Triglycerides | 2015 |
[Antiviral effects of the combination of glycyrrhizin and ribavirin against influenza A H1N1 virus infection in vivo].
Topics: Animals; Antiviral Agents; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Glycyrrhizic Acid; Inflammation; Influenza A Virus, H1N1 Subtype; Interleukin-1beta; Interleukin-6; Lung; Mice; Orthomyxoviridae Infections; Pneumonia, Viral; Ribavirin; Tumor Necrosis Factor-alpha | 2015 |
Glycyrrhizic acid pretreatment prevents sepsis-induced acute kidney injury via suppressing inflammation, apoptosis and oxidative stress.
Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Line; Glycyrrhizic Acid; Inflammation; Inflammation Mediators; Kidney; Lipopolysaccharides; Male; NF-kappa B; Oxidative Stress; Rats; Sepsis; Signal Transduction | 2016 |
High mobility group box1 protein is involved in acute inflammation induced by Clostridium difficile toxin A.
Topics: Animals; Anti-Inflammatory Agents; Bacterial Toxins; Cell Line; Disease Models, Animal; Enterocolitis, Pseudomembranous; Enterotoxins; Female; Glycyrrhizic Acid; HMGB1 Protein; Humans; Inflammation; Inflammation Mediators; Mice; RAW 264.7 Cells; Toll-Like Receptor 4 | 2016 |
Protective effects of glycyrrhizic acid from edible botanical glycyrrhiza glabra against non-alcoholic steatohepatitis in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Diet; Fatty Acids; Glycyrrhiza; Glycyrrhizic Acid; Inflammation; Lipid Metabolism; Lipogenesis; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Triglycerides | 2016 |
Glycyrrhizin ameliorates oxidative stress and inflammation in hippocampus and olfactory bulb in lithium/pilocarpine-induced status epilepticus in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Fluorometry; Glycyrrhizic Acid; Hippocampus; Inflammation; Lithium Compounds; Male; Olfactory Bulb; Oxidative Stress; Pilocarpine; Rats, Wistar; Status Epilepticus; Stereoisomerism | 2016 |
Glycyrrhizin Ameliorates Fibrosis, Vasculopathy, and Inflammation in Animal Models of Systemic Sclerosis.
Topics: Animals; Bleomycin; Disease Models, Animal; Fibroblasts; Fibrosis; Glycyrrhizic Acid; Humans; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Scleroderma, Systemic; Skin; Th2 Cells; Transforming Growth Factor beta; Vascular Diseases | 2017 |
Contrast Media-Induced Renal Inflammation Is Mediated Through HMGB1 and Its Receptors in Human Tubular Cells.
Topics: Active Transport, Cell Nucleus; Cell Line; Cell Nucleus; Chemokine CCL2; Contrast Media; Diatrizoate Meglumine; Epithelial Cells; Gene Expression Regulation; Glycyrrhizic Acid; HMGB1 Protein; Humans; Inflammation; Interleukin-6; Kidney Tubules; Necrosis; Receptors, CXCR4; Signal Transduction; Toll-Like Receptor 2; Transcription Factor RelA | 2017 |
Glycyrrhizin inhibits porcine epidemic diarrhea virus infection and attenuates the proinflammatory responses by inhibition of high mobility group box-1 protein.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Chlorocebus aethiops; Cytokines; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Porcine epidemic diarrhea virus; Swine; Toll-Like Receptor 4; Vero Cells; Virus Internalization; Virus Replication | 2017 |
Glycyrrhizin reduces secondary inflammatory process after spinal cord compression injury in mice.
Topics: Animals; Anti-Inflammatory Agents; bcl-2-Associated X Protein; Glycyrrhizic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation; Male; Mice; Mice, Inbred Strains; Motor Activity; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-bcl-2; Spinal Cord Injuries; Tyrosine | 2009 |
Monoammonium glycyrrhizinate inhibited the inflammation of LPS-induced acute lung injury in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Cyclic AMP; Glycyrrhizic Acid; Inflammation; Interleukin-10; Lipopolysaccharides; Lung Diseases; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Neutrophils; Oxidation-Reduction; Peroxidase; Phosphoric Diester Hydrolases; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2010 |
Glycyrrhizic acid and 18beta-glycyrrhetinic acid inhibit inflammation via PI3K/Akt/GSK3beta signaling and glucocorticoid receptor activation.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Down-Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Glycyrrhetinic Acid; Glycyrrhizic Acid; Inflammation; Mice; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptors, Glucocorticoid; Signal Transduction | 2010 |
Simultaneous determination of liquiritin, hesperidin, and glycyrrhizin by HPLC-photodiode array detection and the anti-inflammatory effect of Pyungwi-san.
Topics: Animals; Anti-Inflammatory Agents; Calibration; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Dinoprostone; Drug Evaluation, Preclinical; Flavanones; Glucosides; Glycyrrhizic Acid; Hesperidin; Inflammation; Male; Medicine, Korean Traditional; Mice; Mice, Inbred BALB C; Plant Extracts; Rats | 2011 |
Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression.
Topics: Active Transport, Cell Nucleus; Antioxidants; Caspases; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cytokines; Enzyme Activation; G1 Phase; Gene Expression Regulation; Glycyrrhizic Acid; Humans; Inflammation; Influenza A Virus, H5N1 Subtype; Influenza, Human; Monocytes; Multiprotein Complexes; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Ribonucleoproteins; Virus Replication | 2011 |
Glycyrrhizic acid and 18β-glycyrrhetinic acid modulate lipopolysaccharide-induced inflammatory response by suppression of NF-κB through PI3K p110δ and p110γ inhibitions.
Topics: Animals; Cell Line; Class Ia Phosphatidylinositol 3-Kinase; Class Ib Phosphatidylinositol 3-Kinase; Down-Regulation; Glycyrrhetinic Acid; Glycyrrhiza; Glycyrrhizic Acid; Inflammation; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Plant Extracts; Signal Transduction | 2011 |
Ameliorative effects of diammonium glycyrrhizinate on inflammation in focal cerebral ischemic-reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents; Brain Ischemia; Glycyrrhizic Acid; Infarction, Middle Cerebral Artery; Inflammation; Male; Mice; Random Allocation; Reperfusion Injury; Treatment Outcome | 2012 |
The role of Glycyrrhizin, an inhibitor of HMGB1 protein, in anticancer therapy.
Topics: Animals; Antineoplastic Agents; Cattle; Cell Proliferation; Endothelial Cells; Glycyrrhizic Acid; HMGB1 Protein; Humans; Inflammation; Melanoma, Experimental; Mice; Necrosis; NIH 3T3 Cells; Peptides; Rats; Saponins | 2012 |
Linoleoyl ethanolamide reduces lipopolysaccharide-induced inflammation in macrophages and ameliorates 2,4-dinitrofluorobenzene-induced contact dermatitis in mice.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cytokines; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Female; Glycyrrhizic Acid; Inflammation; Inflammation Mediators; Linoleic Acids; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; NF-kappa B; Polyunsaturated Alkamides; Signal Transduction | 2013 |
Diammonium glycyrrhizinate attenuates Aβ(1-42) -induced neuroinflammation and regulates MAPK and NF-κB pathways in vitro and in vivo.
Topics: Amyloid beta-Peptides; Animals; Cell Line, Tumor; Glycyrrhizic Acid; Humans; Inflammation; Inflammation Mediators; Male; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; NF-kappa B; Peptide Fragments | 2013 |
Ursodiol use is possibly associated with lower incidence of hepatocellular carcinoma in hepatitis C virus-associated liver cirrhosis.
Topics: Alanine Transaminase; Analysis of Variance; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cholagogues and Choleretics; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Glycyrrhizic Acid; Hepacivirus; Hepatitis C; Humans; Incidence; Inflammation; Liver Cirrhosis; Liver Neoplasms; Logistic Models; Male; Middle Aged; Risk Factors; Treatment Outcome; Ursodeoxycholic Acid | 2005 |
Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice.
Topics: Active Transport, Cell Nucleus; Animals; Chemotaxis; Cytoplasm; Glycyrrhizic Acid; Hepatitis B virus; HMGB1 Protein; Inflammation; Liver Diseases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Necrosis; Neutrophils; RNA, Messenger; T-Lymphocytes, Cytotoxic | 2007 |
A direct inhibitor of HMGB1 cytokine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Glycyrrhizic Acid; HMGB1 Protein; Humans; Inflammation; Inflammation Mediators; Interleukin-33; Interleukins | 2007 |
Antagonism of selectin-dependent adhesion of human eosinophils and neutrophils by glycomimetics and oligosaccharide compounds.
Topics: Antibodies, Monoclonal; Carbohydrate Sequence; Cell Adhesion; Eosinophils; Glycyrrhizic Acid; Humans; Inflammation; Molecular Sequence Data; Molecular Structure; Neutrophils; Oligosaccharides; Selectins; Sialyl Lewis X Antigen | 1998 |
Potential regulation of inflammation in the lung by local metabolism of hydrocortisone.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Carbenoxolone; Cells, Cultured; Cortisone; Endothelium, Vascular; Epithelium; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Inflammation; Kinetics; Lung; Pleura; Trachea | 1991 |