Page last updated: 2024-08-21

glycyrrhizic acid and Cirrhosis, Liver

glycyrrhizic acid has been researched along with Cirrhosis, Liver in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.69)18.7374
1990's3 (11.54)18.2507
2000's9 (34.62)29.6817
2010's6 (23.08)24.3611
2020's6 (23.08)2.80

Authors

AuthorsStudies
Bi, H; Chen, N; Chu, S; Cui, L; Gao, G; He, W; Li, X; Liu, F; Tian, Y; Wang, H; Wang, Z1
Dai, Z; Deng, K; Yang, D; Yang, P; Zhou, Y1
Cai, D; Li, L; Li, S; Lin, Y; Liu, J; Wang, H; Zhao, X1
Cheng, X; Dai, J; Fan, H; Gao, L; Guo, M; Peng, H; Wang, Z; Yuan, N1
Deng, YG; Li, GF; Liu, SJ; Lyu, XL; Zhang, SC; Zhao, BX; Zhu, YL1
Jiang, J; Li, Y; Liu, P; Ma, Y; Meng, C; Shi, R; Wang, T; Wang, Y; Wu, J; Yuan, W; Zeng, J; Zhang, H; Zhong, J; Zhu, L1
Mehtiyev, SN; Mehtiyeva, OA1
Hu, G; Li, X; Lin, Y; Men, X; Meng, X; Zhang, H; Zhen, Y1
Akuta, N; Arase, Y; Fukushima, T; Hosaka, T; Ikeda, K; Kawamura, Y; Kobayashi, M; Kumada, H; Saitoh, S; Sezaki, H; Suzuki, F; Suzuki, Y1
Higashiyama, R; Hong, YY; Inagaki, Y; Inoue, H; Kushida, M; Moro, T; Nakao, S; Okazaki, I; Shimoyama, Y; Sugioka, Y1
Kong, XP; Liu, XY; Wan, HJ; Wang, HC; Wei, SL; Ye, HJ; Yi, XR; Yuan, YC1
Chen, WH; Lu, LG; Qu, Y; Xu, MY; Zong, L1
Chen, Z; Huang, L; Li, Y; Qi, L; Wen, Z1
Jiang, W; Li, J; Li, L; Tu, CT; Wang, FP; Wang, JY1
Wang, LL; Yin, WH; Zhang, YF1
Fujiyama, S; Hirokawa, S; Masaki, T; Miyakawa, K; Ohkawa, S; Tamai, S; Tanaka, K; Tarao, K1
Cai, WM; Dooley, S; Jia, JD; Mertens, PR; Wang, BE; Weng, HL; Wu, WF; Xian, JZ1
Han, DW; Li, CM; Ma, XH; Yin, L; Zhao, MQ; Zhao, YC1
Aikawa, T; Iga, T; Kotaki, H; Osuga, T; Santa, T; Sawada, Y; Tanaka, N; Uchino, K; Yamamura, Y1
Kiriyama, S; Kumada, T; Nakano, S; Osada, T; Samori, T; Shimada, S; Sugiyama, K; Takahashi, M; Takeda, I; Toyoda, H1
Hop, WC; Schalm, SW; van Rossum, TG; Vulto, AG1
Harada, H; Kamitsukasa, H; Kojima, H; Murai, S; Tokita, H; Yagura, M1
Akagi, S; Hamamoto, S; Kinoshita, Y; Kohge, N; Mishiro, T; Moritani, M; Sato, S; Uchida, Y; Watanabe, M1
Kumada, H1
Sata, M; Ueno, T1
Arima, T; Nagashima, H; Wada, T1

Reviews

2 review(s) available for glycyrrhizic acid and Cirrhosis, Liver

ArticleYear
[[New Paradigm Challenges of Steatosis Treatment in the Practice Therapist].]
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2016, Issue:5

    Topics: Adult; Drug Combinations; Fatty Liver; Glycyrrhizic Acid; Humans; Liver Cirrhosis; Liver Function Tests; Male; Phosphatidylcholines; Practice Patterns, Physicians'; Treatment Outcome; Ultrasonography; Ursodeoxycholic Acid

2016
[Forefront of therapy for hepatic fibrosis].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2002, Volume: 99, Issue:4

    Topics: Animals; Drugs, Chinese Herbal; Genetic Therapy; Glycyrrhizic Acid; Humans; Interferon-alpha; Interferon-beta; Lamivudine; Liver Cirrhosis; Liver Cirrhosis, Experimental; Mice; Rats

2002

Trials

5 trial(s) available for glycyrrhizic acid and Cirrhosis, Liver

ArticleYear
Pharmacokinetics-based comprehensive strategy to identify multiple effective components in Huangqi decoction against liver fibrosis.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 84

    Topics: Adolescent; Adult; Animals; Chalcone; Chromatography, Liquid; Drugs, Chinese Herbal; Flavanones; Glucosides; Glycyrrhizic Acid; Humans; Liver Cirrhosis; Male; Mass Spectrometry; Mice, Inbred C57BL; Middle Aged; Saponins; Triterpenes; Young Adult

2021
[Clinical observation on the anti-liver fibrosis treatment by diammonion glycyrrhizinate injection combined with salvia].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2002, Volume: 22, Issue:7

    Topics: Adolescent; Adult; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Glycyrrhizic Acid; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Male; Middle Aged; Phytotherapy; Salvia miltiorrhiza

2002
Effect of interferon-gamma on hepatic fibrosis in chronic hepatitis B virus infection: a randomized controlled study.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:8

    Topics: Actins; Adult; Anti-Infective Agents; Biopsy, Needle; Collagen Type III; Collagen Type IV; Drug Therapy, Combination; Female; Glycyrrhizic Acid; Hepatitis B, Chronic; Humans; Hyaluronic Acid; Injections, Intramuscular; Interferon-gamma; Laminin; Liver; Liver Cirrhosis; Male; Muscle, Smooth; Potassium Magnesium Aspartate; Prospective Studies; Severity of Illness Index; Smad2 Protein

2005
The relationship between pharmacokinetic behaviour of glycyrrhizin and hepatic function in patients with acute hepatitis and liver cirrhosis.
    Biopharmaceutics & drug disposition, 1995, Volume: 16, Issue:1

    Topics: Adult; Aged; Alanine Transaminase; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Half-Life; Hepatitis; Humans; Injections, Intravenous; Liver; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged

1995
Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection.
    Clinical therapeutics, 1999, Volume: 21, Issue:12

    Topics: Adult; Aged; Antiviral Agents; Area Under Curve; Chromatography, High Pressure Liquid; Female; Glycyrrhizic Acid; Half-Life; Hepatitis C, Chronic; Humans; Injections, Intravenous; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Regression Analysis

1999

Other Studies

19 other study(ies) available for glycyrrhizic acid and Cirrhosis, Liver

ArticleYear
Up-regulation of Nrf2/P62/Keap1 involves in the anti-fibrotic effect of combination of monoammonium glycyrrhizinate and cysteine hydrochloride induced by CCl
    European journal of pharmacology, 2021, Dec-15, Volume: 913

    Topics: Animals; Antifibrotic Agents; Carbon Tetrachloride; Cysteine; Disease Models, Animal; Gene Knockdown Techniques; Gene Knockout Techniques; Glycyrrhizic Acid; Hep G2 Cells; Hepatocytes; Humans; Kelch-Like ECH-Associated Protein 1; Liver Cirrhosis; Male; NF-E2-Related Factor 2; Oxidative Stress; Rats; Sequestosome-1 Protein; Signal Transduction; Up-Regulation

2021
LPS-induced macrophage exosomes promote the activation of hepatic stellate cells and the intervention study of total astragalus saponins combined with glycyrrhizic acid.
    Anatomical record (Hoboken, N.J. : 2007), 2023, Volume: 306, Issue:12

    Topics: Exosomes; Glycyrrhizic Acid; Hepatic Stellate Cells; Humans; Lipopolysaccharides; Liver Cirrhosis; Macrophages; Saponins

2023
Diammonium glycyrrhizinate ameliorates portal hypertension by regulating portal macrophage oxidation and superoxide dismutase 3.
    European journal of pharmacology, 2022, Aug-15, Volume: 929

    Topics: Animals; Glycyrrhizic Acid; Hypertension, Portal; Liver Cirrhosis; Macrophages; Nitric Oxide; Portal Pressure; Rats; Superoxide Dismutase

2022
Glycyrrhizic acid alleviates liver fibrosis in vitro and in vivo via activating CUGBP1-mediated IFN-γ/STAT1/Smad7 pathway.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 112

    Topics: Animals; CELF1 Protein; Glycyrrhizic Acid; Hepatic Stellate Cells; Humans; Interferon-gamma; Liver; Liver Cirrhosis; Mice; Molecular Docking Simulation; Signal Transduction; Smad7 Protein; STAT1 Transcription Factor; Transforming Growth Factor beta1

2023
[Preparation of evodiamine-glycyrrhizic acid micelles with glycyrrhizic acid as carrier and their anti-hepatic fibrosis activity].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2020, Volume: 45, Issue:13

    Topics: Animals; Drug Carriers; Glycyrrhizic Acid; Liver Cirrhosis; Micelles; Particle Size; Quinazolines; Rats; Solubility

2020
Therapeutic Effect of Glycyrrhizin Arginine Salt on Rat Cholestatic Cirrhosis and its Mechanism.
    The American journal of Chinese medicine, 2018, Volume: 46, Issue:5

    Topics: Animals; Arginine; Aspartate Aminotransferases; Bilirubin; Cholestasis; Dinoprost; Drugs, Chinese Herbal; Glycyrrhizic Acid; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1

2018
Prevention of disease progression with anti-inflammatory therapy in patients with HCV-related cirrhosis: a Markov model.
    Oncology, 2014, Volume: 86, Issue:5-6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antiviral Agents; Carcinoma, Hepatocellular; Disease Progression; Female; Glycyrrhizic Acid; Hepatitis C, Chronic; Humans; Interferons; Liver Cirrhosis; Liver Neoplasms; Male; Markov Chains; Middle Aged; Young Adult

2014
Glycyrrhizin and its metabolite inhibit Smad3-mediated type I collagen gene transcription and suppress experimental murine liver fibrosis.
    Life sciences, 2008, Oct-10, Volume: 83, Issue:15-16

    Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Carbon Tetrachloride Poisoning; Carcinoma, Hepatocellular; Cells, Cultured; Collagen Type I; Fluorescent Antibody Technique; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycyrrhizic Acid; Humans; Indicators and Reagents; Liver Cirrhosis; Luciferases; Mice; Mitogen-Activated Protein Kinases; Mutant Chimeric Proteins; Promoter Regions, Genetic; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad3 Protein; Transcription, Genetic

2008
[Therapeutic effects of compound glycyrrhizin liposome on fibrosis of the rats with nonalcoholic steatohepatitis].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2009, Volume: 17, Issue:11

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Dietary Fats; Disease Models, Animal; Drugs, Chinese Herbal; Fatty Liver; Glycyrrhizic Acid; Injections; Liposomes; Liver; Liver Cirrhosis; Male; Phenanthrolines; Random Allocation; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Treatment Outcome

2009
18α-Glycyrrhizin induces apoptosis and suppresses activation of rat hepatic stellate cells.
    Medical science monitor : international medical journal of experimental and clinical research, 2012, Volume: 18, Issue:1

    Topics: Actins; Animals; Apoptosis; Carbon Tetrachloride; Cell Proliferation; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Hepatic Stellate Cells; Immunohistochemistry; In Situ Nick-End Labeling; Liver Cirrhosis; NF-kappa B; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction

2012
[Optimization of a compound prescription for treating liver fibrosis].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2012, Volume: 32, Issue:1

    Topics: Alkaloids; Animals; Drug Therapy, Combination; Female; Glycyrrhizic Acid; Liver Cirrhosis; Male; Matrines; Phytotherapy; Quinolizines; Rats; Rats, Sprague-Dawley; Thioacetamide

2012
Glycyrrhizin regulates CD4+T cell response during liver fibrogenesis via JNK, ERK and PI3K/AKT pathway.
    International immunopharmacology, 2012, Volume: 14, Issue:4

    Topics: Animals; CD4-Positive T-Lymphocytes; Cell Proliferation; Concanavalin A; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation; Glycyrrhizic Acid; Interferon-gamma; Interleukin-10; Liver Cirrhosis; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Phosphatidylinositol 3-Kinases

2012
Ursodiol use is possibly associated with lower incidence of hepatocellular carcinoma in hepatitis C virus-associated liver cirrhosis.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:1

    Topics: Alanine Transaminase; Analysis of Variance; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cholagogues and Choleretics; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Glycyrrhizic Acid; Hepacivirus; Hepatitis C; Humans; Incidence; Inflammation; Liver Cirrhosis; Liver Neoplasms; Logistic Models; Male; Middle Aged; Risk Factors; Treatment Outcome; Ursodeoxycholic Acid

2005
[Preventive and therapeutic actions of glycyrrhizin, glycyrrhetic acid and crude saikosides on experimental liver cirrhosis in rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1983, Volume: 18, Issue:5

    Topics: Animals; Collagen; Fatty Liver; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hepatitis; Liver Cirrhosis; Male; Oleanolic Acid; Rats; Sapogenins; Saponins

1983
[The pharmacokinetics of the glycyrrhizin and glycyrrhetic acid after intravenous administration of glycyrrhizin for the patients with chronic liver disease caused by type C hepatitis virus].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1995, Volume: 92, Issue:12

    Topics: Aged; Antiviral Agents; Chronic Disease; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hepatitis C; Humans; Infusions, Intravenous; Liver Cirrhosis; Male; Middle Aged

1995
Changes of liver fibrosis in chronic hepatitis C patients with no response to interferon-alpha therapy: including quantitative assessment by a morphometric method.
    Journal of gastroenterology, 2000, Volume: 35, Issue:2

    Topics: Alanine Transaminase; Antiviral Agents; Biomarkers; Biopsy; Disease Progression; Drugs, Chinese Herbal; Female; Glycyrrhizic Acid; Hepatitis C; Hepatitis C, Chronic; Humans; Injections, Intramuscular; Interferon-alpha; Liver Cirrhosis; Male; Middle Aged; Peptide Fragments; Procollagen; Retrospective Studies; RNA, Viral; Ursodeoxycholic Acid

2000
Report of a case showing a recovery from liver cirrhosis to chronic hepatitis, type C, after glycyrrhizin injection for 2 years and a sustained response by the following interferon therapy.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:6

    Topics: Adult; Drug Therapy, Combination; Female; Glycyrrhizic Acid; Hepatitis C, Chronic; Humans; Injections; Interferon-beta; Laparoscopy; Liver; Liver Cirrhosis

2001
Long-term treatment of chronic hepatitis C with glycyrrhizin [stronger neo-minophagen C (SNMC)] for preventing liver cirrhosis and hepatocellular carcinoma.
    Oncology, 2002, Volume: 62 Suppl 1

    Topics: Alanine Transaminase; Antiviral Agents; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chronic Disease; Glycyrrhizic Acid; Hepatitis C; Humans; Liver Cirrhosis; Liver Neoplasms; Survival Analysis

2002
Natural killer activity in patients with chronic hepatitis treated with OK432, interferon, adenine arabinoside and glycyrrhizin.
    Gastroenterologia Japonica, 1987, Volume: 22, Issue:3

    Topics: Adult; Carcinoma, Hepatocellular; Chronic Disease; Cytotoxicity, Immunologic; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hepatitis B; Humans; Interferon Type I; Killer Cells, Natural; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Picibanil; Radioimmunoassay; Skin Tests; Vidarabine

1987