Page last updated: 2024-08-21

glycyrrhizic acid and Cancer of Liver

glycyrrhizic acid has been researched along with Cancer of Liver in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.03)18.7374
1990's2 (6.06)18.2507
2000's11 (33.33)29.6817
2010's12 (36.36)24.3611
2020's7 (21.21)2.80

Authors

AuthorsStudies
Chen, YS; Chung, JG; Hsu, FT; Kuo, CY; Pan, PJ; Tsai, JJ; Wang, WS1
Hao, M; Li, Y; Lu, S; Ma, W; Wang, P; Zhang, B; Zhang, D1
Huang, JF; Huang, ZJ; Li, YF; Liu, HG; Wei, MJ; Wu, JP; Xu, ZJ; Yan, YY; Zhang, XM1
Chen, T; Chen, Y; Han, T; Li, Q; Li, Y; Liu, Y; Zhao, M1
Cai, Y; Chen, J; Huang, Y; Leung, GP; Li, J; Seto, SW; Wu, Y; Xu, Z; Zhang, J1
Cao, M; Gao, Y; Piao, Y; Qiu, N; Shen, Y; Zhan, M; Zhou, Z1
Peng, C; Sun, Z; Tan, Z; Yi, W1
Bryson, S; Castino, G; Del Río Hernández, A; Julian, L; McGarry, L; Mullin, M; Munro, J; Naylor, G; Olson, MF; Rath, N; Rice, A; Stevenson, D; Wickman, GR1
Deng, Y; Feng, Z; Huang, Y; Lian, B; Wang, L; Wu, M; Wu, W; Zhao, X; Zhong, C; Zu, C1
Ding, R; Dou, K; He, G; Li, X; Ma, B; Peng, W; Qu, S; Tao, K; Yang, H; Yang, Z; Yue, S; Zhang, H; Zhang, X; Zhang, Z1
Badria, FA; El-Senduny, FF; Youssef, MM; Zidane, MM1
Deng, Y; Ge, Y; Meng, L; Yu, X; Zhang, Y; Zhao, X; Zu, Y1
Akuta, N; Arase, Y; Fukushima, T; Hosaka, T; Ikeda, K; Kawamura, Y; Kobayashi, M; Kumada, H; Saitoh, S; Sezaki, H; Suzuki, F; Suzuki, Y1
Matsumura, H; Matsuoka, S; Moriyama, M; Nakamura, H; Nirei, K1
Rino, Y; Yamamoto, N; Yukawa, N1
Arteta, B; Benedicto, A; Hernandez-Unzueta, I; Márquez, J; Mena, J; Olaso, E; Sanz, E1
Koike, K1
Ji, LN; Mao, ZW; Zhao, MX1
Shi, L; Tang, C; Yin, C1
Bleiberg, H; Gerard, B1
Fujiyama, S; Hirokawa, S; Masaki, T; Miyakawa, K; Ohkawa, S; Tamai, S; Tanaka, K; Tarao, K1
Akuta, N; Arase, Y; Hosaka, T; Ikeda, K; Kobayashi, M; Kumada, H; Saitoh, S; Sezaki, H; Someya, T; Suzuki, F; Suzuki, Y1
Hansen, BE; Ikeda, K; Schalm, SW; Suzuki, H; Veldt, BJ; Verhey, E1
Hachimine, D; Nakahashi, Y; Okazaki, K; Seki, T; Wakamatsu, T1
Li, Q; Murakamio, T; Okita, K; Takahashi, M1
Arase, Y; Chayama, K; Ikeda, K; Kobayashi, M; Koida, I; Kumada, H; Murashima, N; Saitoh, S; Suzuki, Y; Tsubota, A1
Kasahara, A1
Iino, S; Miyakawa, Y1
Kojima, S; Moriwaki, H; Okuno, M1
Kumada, H1
Hino, O; Kajino, K; Okamoto, T1
Chao, DC; Ho, TY; Hsiang, CY; Lai, IL1
Arima, T; Nagashima, H; Wada, T1

Reviews

5 review(s) available for glycyrrhizic acid and Cancer of Liver

ArticleYear
Meta-analysis of the efficacy of glycyrrhizin for postoperative liver preservation in patients with liver cancer.
    Journal of cancer research and therapeutics, 2022, Volume: 18, Issue:2

    Topics: Drugs, Chinese Herbal; Glycyrrhizic Acid; Humans; Liver Function Tests; Liver Neoplasms

2022
Does herbal medicine reduce the risk of hepatocellular carcinoma?
    World journal of gastroenterology, 2015, Oct-07, Volume: 21, Issue:37

    Topics: Animals; Anti-Inflammatory Agents; Benzimidazoles; Carcinoma, Hepatocellular; Clinical Trials as Topic; Cysteine; Drug Combinations; Drugs, Chinese Herbal; Fatty Liver; Fluorenes; Glycine; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hepacivirus; Hepatitis C, Chronic; Humans; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Phytotherapy; Plant Preparations; Sofosbuvir; Tablets

2015
Treatment of hepatocarcinoma.
    Current oncology reports, 2004, Volume: 6, Issue:3

    Topics: Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carcinoma, Hepatocellular; Catheter Ablation; Cryotherapy; Drug Therapy, Combination; Ethanol; Glycyrrhizic Acid; Hepatitis B; Humans; Interferon-alpha; Liver Neoplasms; Liver Transplantation; Risk Factors; Survival Rate

2004
Treatment strategies for chronic hepatitis C virus infection.
    Journal of gastroenterology, 2000, Volume: 35, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Carcinoma, Hepatocellular; Drugs, Chinese Herbal; Glycyrrhizic Acid; Hepatitis C, Chronic; Humans; Interferons; Iron Overload; Liver Neoplasms; Ribavirin; Treatment Outcome; Ursodeoxycholic Acid

2000
Chemoprevention of hepatocellular carcinoma: concept, progress and perspectives.
    Journal of gastroenterology and hepatology, 2001, Volume: 16, Issue:12

    Topics: alpha-Fetoproteins; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carcinoma, Hepatocellular; Clonal Deletion; Glycyrrhizic Acid; Humans; Interferon-alpha; Liver Neoplasms; Prognosis; Tretinoin

2001

Trials

1 trial(s) available for glycyrrhizic acid and Cancer of Liver

ArticleYear
Incidence of hepatocellular carcinoma reduced by phlebotomy treatment in patients with chronic hepatitis C.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:2

    Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Carcinoma, Hepatocellular; Female; Glycyrrhizic Acid; Hepatitis C, Chronic; Humans; Incidence; Interferon-alpha; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Phlebotomy; Platelet Count; Ursodeoxycholic Acid

2015

Other Studies

27 other study(ies) available for glycyrrhizic acid and Cancer of Liver

ArticleYear
DNA damage and NF-κB inactivation implicate glycyrrhizic acid-induced G
    Journal of food biochemistry, 2022, Volume: 46, Issue:7

    Topics: Carcinoma, Hepatocellular; DNA Damage; Glycyrrhizic Acid; Humans; Liver Neoplasms; NF-kappa B

2022
Effects of microwave ablation on serum Golgi protein 73 in patients with primary liver cancer.
    World journal of gastroenterology, 2022, Aug-07, Volume: 28, Issue:29

    Topics: Alanine Transaminase; alpha-Fetoproteins; Aspartate Aminotransferases; Bilirubin; Biomarkers; Carcinoma, Hepatocellular; Glutathione; Glycyrrhizic Acid; Humans; Liver Neoplasms; Membrane Proteins; Microwaves; Retrospective Studies; Serum Albumin

2022
Identification of the Mechanism of Matrine Combined with Glycyrrhizin for Hepatocellular Carcinoma Treatment through Network Pharmacology and Bioinformatics Analysis.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Alkaloids; Carcinoma, Hepatocellular; Computational Biology; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glycyrrhizic Acid; Humans; Liver Neoplasms; Matrines; Network Pharmacology; Quinolizines

2022
Glycyrrhizic Acid-Lipid Framework Nanovehicle Loading Triptolide for Combined Immunochemotherapy.
    ACS applied materials & interfaces, 2023, Sep-06, Volume: 15, Issue:35

    Topics: Carcinoma, Hepatocellular; Glycyrrhizic Acid; Humans; Lipids; Liposomes; Liver Neoplasms

2023
Glycyrrhizin Acid and Glycyrrhetinic Acid Modified Polyethyleneimine for Targeted DNA Delivery to Hepatocellular Carcinoma.
    International journal of molecular sciences, 2019, Oct-12, Volume: 20, Issue:20

    Topics: Animals; Carcinoma, Hepatocellular; Endocytosis; Female; Gene Transfer Techniques; Genes, Reporter; Genetic Therapy; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Nanoparticles; Polyethyleneimine

2019
HK2 is associated with the Warburg effect and proliferation in liver cancer: Targets for effective therapy with glycyrrhizin.
    Molecular medicine reports, 2021, Volume: 23, Issue:5

    Topics: Apoptosis; Cell Proliferation; Glycolysis; Glycyrrhizic Acid; Hep G2 Cells; Hexokinase; Humans; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Signal Transduction; Warburg Effect, Oncologic

2021
Defective apoptotic cell contractility provokes sterile inflammation, leading to liver damage and tumour suppression.
    eLife, 2021, 04-19, Volume: 10

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Caspases; Cell Shape; Chemical and Drug Induced Liver Injury; Diethylnitrosamine; Disease Models, Animal; Enzyme Activation; Glycyrrhizic Acid; HEK293 Cells; HMGB1 Protein; Humans; Liver; Liver Neoplasms; Male; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Transgenic; Mutation; Myosin Light Chains; Neutrophil Infiltration; Phosphorylation; rho-Associated Kinases; Sulfonamides; Toll-Like Receptor 4

2021
Resveratrol-loaded glycyrrhizic acid-conjugated human serum albumin nanoparticles wrapping resveratrol nanoparticles: Preparation, characterization, and targeting effect on liver tumors.
    Journal of biomaterials applications, 2017, Volume: 32, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Delayed-Action Preparations; Drug Delivery Systems; Glycyrrhizic Acid; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; Mice; Nanoparticles; Resveratrol; Serum Albumin, Human; Stilbenes

2017
The mTOR inhibition in concurrence with ERK1/2 activation is involved in excessive autophagy induced by glycyrrhizin in hepatocellular carcinoma.
    Cancer medicine, 2017, Volume: 6, Issue:8

    Topics: Animals; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Glycyrrhizic Acid; Humans; Liver Neoplasms; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays

2017
An Approach to Treatment of Liver Cancer by Novel Glycyrrhizin Derivative.
    Anti-cancer agents in medicinal chemistry, 2019, Volume: 19, Issue:15

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Survival; Drug Screening Assays, Antitumor; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hep G2 Cells; Humans; Liver Neoplasms; Molecular Structure; Structure-Activity Relationship; Triterpenes

2019
Preparation of 10-hydroxycamptothecin-loaded glycyrrhizic acid-conjugated bovine serum albumin nanoparticles for hepatocellular carcinoma-targeted drug delivery.
    International journal of nanomedicine, 2013, Volume: 8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Cattle; Cell Line, Tumor; Drug Carriers; Glycyrrhizic Acid; Hemolysis; Humans; Liver Neoplasms; Nanoparticles; Particle Size; Rabbits; Serum Albumin, Bovine

2013
Prevention of disease progression with anti-inflammatory therapy in patients with HCV-related cirrhosis: a Markov model.
    Oncology, 2014, Volume: 86, Issue:5-6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antiviral Agents; Carcinoma, Hepatocellular; Disease Progression; Female; Glycyrrhizic Acid; Hepatitis C, Chronic; Humans; Interferons; Liver Cirrhosis; Liver Neoplasms; Male; Markov Chains; Middle Aged; Young Adult

2014
Ocoxin® oral solution slows down tumor growth in an experimental model of colorectal cancer metastasis to the liver in Balb/c mice.
    Oncology reports, 2016, Volume: 35, Issue:3

    Topics: Animals; Apoptosis; Ascorbic Acid; Caspase 3; Cell Proliferation; Colorectal Neoplasms; Folic Acid; Gene Expression Regulation, Neoplastic; Glycyrrhizic Acid; Humans; Ki-67 Antigen; Liver Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Pantothenic Acid; Plant Extracts; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Zinc; Zinc Sulfate

2016
Expression of junB is markedly stimulated by glycyrrhizin in a human hepatoma cell line.
    Oncology reports, 2011, Volume: 25, Issue:3

    Topics: Anti-Inflammatory Agents; Carcinoma, Hepatocellular; Drug Evaluation, Preclinical; Gene Expression Regulation, Neoplastic; Glycyrrhizic Acid; Hep G2 Cells; Humans; Liver Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Up-Regulation

2011
β-Cyclodextrin/glycyrrhizic acid functionalised quantum dots selectively enter hepatic cells and induce apoptosis.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2012, Feb-06, Volume: 18, Issue:6

    Topics: Apoptosis; beta-Cyclodextrins; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; G1 Phase; Glycyrrhizic Acid; HeLa Cells; Hep G2 Cells; Humans; Liver Neoplasms; Mitochondria; Quantum Dots; Reactive Oxygen Species; Resting Phase, Cell Cycle

2012
Glycyrrhizin-modified O-carboxymethyl chitosan nanoparticles as drug vehicles targeting hepatocellular carcinoma.
    Biomaterials, 2012, Volume: 33, Issue:30

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Delivery Systems; Endocytosis; Female; Glycyrrhizic Acid; Humans; Liver; Liver Neoplasms; Mice; Nanoparticles; Paclitaxel; Particle Size; Rhodamines; Spectroscopy, Fourier Transform Infrared; Static Electricity; Subcellular Fractions; Tissue Distribution; Treatment Outcome; Tumor Burden

2012
Ursodiol use is possibly associated with lower incidence of hepatocellular carcinoma in hepatitis C virus-associated liver cirrhosis.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:1

    Topics: Alanine Transaminase; Analysis of Variance; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cholagogues and Choleretics; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Glycyrrhizic Acid; Hepacivirus; Hepatitis C; Humans; Incidence; Inflammation; Liver Cirrhosis; Liver Neoplasms; Logistic Models; Male; Middle Aged; Risk Factors; Treatment Outcome; Ursodeoxycholic Acid

2005
A long-term glycyrrhizin injection therapy reduces hepatocellular carcinogenesis rate in patients with interferon-resistant active chronic hepatitis C: a cohort study of 1249 patients.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Case-Control Studies; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Female; Glycyrrhizic Acid; Hepatitis C, Chronic; Humans; Incidence; Injections, Intravenous; Interferon alpha-2; Interferon-alpha; Liver Function Tests; Liver Neoplasms; Long-Term Care; Male; Middle Aged; Multivariate Analysis; Probability; Prognosis; Recombinant Proteins; Retrospective Studies; Risk Assessment; Severity of Illness Index; Treatment Outcome

2006
Long-term clinical outcome and effect of glycyrrhizin in 1093 chronic hepatitis C patients with non-response or relapse to interferon.
    Scandinavian journal of gastroenterology, 2006, Volume: 41, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antiviral Agents; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Glycyrrhizic Acid; Hepatitis C, Chronic; Humans; Incidence; Injections, Intravenous; Interferons; Japan; Liver Neoplasms; Male; Middle Aged; Recurrence; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome

2006
The combination of glycyrrhizin and lamivudine can reverse the cisplatin resistance in hepatocellular carcinoma cells through inhibition of multidrug resistance-associated proteins.
    International journal of oncology, 2007, Volume: 31, Issue:6

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Line, Tumor; Cisplatin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glycyrrhizic Acid; Humans; Lamivudine; Liver Neoplasms; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Reverse Transcriptase Polymerase Chain Reaction

2007
Anti-growth effects with components of Sho-saiko-to (TJ-9) on cultured human hepatoma cells.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1993, Volume: 2, Issue:2

    Topics: alpha-Fetoproteins; Antineoplastic Agents; Astringents; Carcinoma, Hepatocellular; Cell Cycle; Cell Death; Cell Division; DNA, Neoplasm; Drugs, Chinese Herbal; Flavanones; Flavonoids; Ginsenosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Liver Neoplasms; Oleanolic Acid; Panax; Plants, Medicinal; Sapogenins; Saponins; Tumor Cells, Cultured

1993
The long term efficacy of glycyrrhizin in chronic hepatitis C patients.
    Cancer, 1997, Apr-15, Volume: 79, Issue:8

    Topics: Adult; Antineoplastic Agents; Antiviral Agents; Carcinoma, Hepatocellular; Cause of Death; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hepatitis C; Hepatitis, Chronic; Humans; Japan; Liver Neoplasms; Long-Term Care; Male; Middle Aged; Regression Analysis; Retrospective Studies

1997
Toward prevention of hepatocellular carcinoma developing in chronic hepatitis C.
    Journal of gastroenterology and hepatology, 2001, Volume: 16, Issue:7

    Topics: Carcinoma, Hepatocellular; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hepatitis C, Chronic; Humans; Hyperaldosteronism; Liver Neoplasms

2001
Long-term treatment of chronic hepatitis C with glycyrrhizin [stronger neo-minophagen C (SNMC)] for preventing liver cirrhosis and hepatocellular carcinoma.
    Oncology, 2002, Volume: 62 Suppl 1

    Topics: Alanine Transaminase; Antiviral Agents; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Chronic Disease; Glycyrrhizic Acid; Hepatitis C; Humans; Liver Cirrhosis; Liver Neoplasms; Survival Analysis

2002
Hepatoprotective drugs for the treatment of virus-induced chronic hepatitis: from hypercarcinogenic state to hypocarcinogenic state.
    Japanese journal of pharmacology, 2001, Volume: 87, Issue:3

    Topics: Alanine Transaminase; Carcinoma, Hepatocellular; Coumarins; Glycyrrhizic Acid; Hepatitis C, Chronic; Humans; Interferons; Liver; Liver Neoplasms; Protective Agents

2001
Differential regulation of activator protein 1 activity by glycyrrhizin.
    Life sciences, 2002, Feb-22, Volume: 70, Issue:14

    Topics: Animals; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cell Survival; Chlorocebus aethiops; Dose-Response Relationship, Drug; Gene Expression Regulation; Glycyrrhizic Acid; Humans; Liver Neoplasms; Promoter Regions, Genetic; Response Elements; TATA Box; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection; Tumor Cells, Cultured; Vero Cells

2002
Natural killer activity in patients with chronic hepatitis treated with OK432, interferon, adenine arabinoside and glycyrrhizin.
    Gastroenterologia Japonica, 1987, Volume: 22, Issue:3

    Topics: Adult; Carcinoma, Hepatocellular; Chronic Disease; Cytotoxicity, Immunologic; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hepatitis B; Humans; Interferon Type I; Killer Cells, Natural; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Picibanil; Radioimmunoassay; Skin Tests; Vidarabine

1987