glycyrrhizic acid has been researched along with Alloxan Diabetes in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 13 (54.17) | 24.3611 |
| 2020's | 7 (29.17) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Du, L; Feng, Y; Leng, Y; Shen, J; Yang, H; Zhang, X; Zhou, Z | 1 |
| Chen, ML; Leng, Y; Shen, JH; Shen, Y; Tang, J; Xu, TF; Ye, YL; Yin, HZ; Zhou, Z; Zou, HJ | 1 |
| Li, W; Zhang, D; Zhao, Y | 1 |
| Chen, F; Song, J | 1 |
| Du, J; Hu, R; Li, X; Li, Y; Liu, S | 1 |
| Chattopadhyay, M; Sadanandan, J; Thakur, V | 1 |
| Li, T; Zhang, W; Zhang, XJ; Zhu, ZY | 1 |
| Guo, F; Hou, S; Li, Y; Niu, X; Wu, Z; Yao, N; Zhang, T | 1 |
| Hou, Y; Li, Q; Wu, X; Xin, M | 1 |
| Dahiya, S; Dhingra, D; Dilbaghi, N; Kim, KH; Kumar, S; Rani, R | 1 |
| Cheng, JT; Cheng, KC; Li, Y; Niu, CS; Niu, HS; Wang, LY | 1 |
| Chen, J; Li, W; Shi, M; Zhang, H; Zhang, R; Zhang, X | 1 |
| Akutagawa, K; Fujita, T; Kajiya, M; Kuramitsu, S; Kurihara, H; Matsuda, S; Mizuno, N; Ouhara, K; Shiba, H; Takemura, T; Tari, M | 1 |
| Dahiya, S; Dhingra, D; Dilbaghi, N; Kaushik, A; Kim, KH; Kumar, S; Rani, R | 1 |
| Hsieh, CH; Liu, WH; Wang, ZH; Yin, MC | 1 |
| Abu El-Asrar, AM; Geboes, K; Mohammad, G; Nawaz, MI; Siddiquei, MM | 1 |
| Abu El-Asrar, AM; Mohammad, G; Nawaz, MI; Siddiquei, MM | 1 |
| Abu El-Asrar, AM; Alam, K; Mohammad, G; Mousa, A; Nawaz, MI; Siddiquei, MM | 1 |
| Chen, JZ; Dai, Q; Li, R; Wei, ZH; Wu, H; Xie, J; Xu, B; Zhang, XL | 1 |
| Abu El-Asrar, AM; Alam, K; Jomar, D; Mohammad, G; Siddiquei, MM | 1 |
| Kalaiarasi, P; Pugalendi, KV | 1 |
| Chakraborti, AS; Roy, M; Sen, S | 1 |
| Abu El-Asrar, AM; Al-Shabrawey, M; Mohammad, G; Othman, A; Siddiquei, MM | 1 |
| Ao, Y; Chen, J; Peng, RX; Yue, J | 1 |
24 other study(ies) available for glycyrrhizic acid and Alloxan Diabetes
| Article | Year |
|---|---|
4-(Phenylsulfonamidomethyl)benzamides as potent and selective inhibitors of the 11beta-hydroxysteroid dehydrogenase type 1 with efficacy in diabetic ob/ob mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Benzamides; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Discovery; Humans; Hydrolysis; Inhibitory Concentration 50; Mice; Mice, Obese; Models, Chemical; Structure-Activity Relationship; Sulfonamides | 2009 |
Discovery of novel dual functional agent as PPARgamma agonist and 11beta-HSD1 inhibitor for the treatment of diabetes.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Body Weight; Diabetes Mellitus, Experimental; Fats; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Mice; Models, Molecular; Obesity; Phenylpropionates; PPAR gamma; Rats; Rats, Wistar | 2009 |
Gycyrrhizic acid alleviates atherosclerotic lesions in rats with diabetes mellitus.
Topics: Animals; Atherosclerosis; Diabetes Mellitus, Experimental; Glycyrrhizic Acid; HMGB1 Protein; Humans; Macrophage Activation; Male; Rats; Rats, Sprague-Dawley; Streptozocin | 2021 |
Cardioprotective Action of Glycyrrhizin on Diabetic Rats with Myocardial Remodeling.
Topics: Animals; Diabetes Mellitus, Experimental; Fibrosis; Glycyrrhizic Acid; Heart; Myocardium; Rats | 2021 |
Glycyrrhizin ameliorates vascular endothelial cell senescence by inhibiting HMGB1 in HFD/STZ-induced diabetic rats and human umbilical vein endothelial cells.
Topics: Animals; Cellular Senescence; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Endothelial Cells; Glucose; Glycyrrhizic Acid; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Rats; Rats, Sprague-Dawley; Streptozocin; Vascular System Injuries | 2022 |
High-Mobility Group Box 1 Protein Signaling in Painful Diabetic Neuropathy.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glycyrrhizic Acid; HMGB1 Protein; Humans; Inflammation; Male; Mice; Microglia; Neurons; Pain; Peripheral Nervous System Diseases; Quality of Life; Rats; Receptor for Advanced Glycation End Products; Signal Transduction | 2020 |
Hypoglycemic effect of glycyrrhizic acid, a natural non-carbohydrate sweetener, on streptozotocin-induced diabetic mice.
Topics: alpha-Glucosidases; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drinking; Eating; Glycoside Hydrolase Inhibitors; Glycyrrhizic Acid; Lipoproteins, HDL; Lipoproteins, LDL; Male; Mice; Sodium Cholate; Spectroscopy, Fourier Transform Infrared; Sweetening Agents; Triglycerides | 2020 |
Ability of Post-treatment Glycyrrhizic Acid to Mitigate Cerebral Ischemia/Reperfusion Injury in Diabetic Mice.
Topics: Animals; Cerebrovascular Disorders; Diabetes Complications; Diabetes Mellitus, Experimental; Gene Expression Regulation; Glycyrrhizic Acid; Male; Mice; Reperfusion Injury | 2020 |
Glycyrrhizin micelle as a genistein nanocarrier: Synergistically promoting corneal epithelial wound healing through blockage of the HMGB1 signaling pathway in diabetic mice.
Topics: Administration, Ophthalmic; Animals; Blotting, Western; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Carriers; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Genistein; Glycyrrhizic Acid; HMGB1 Protein; Male; Mice; Mice, Inbred C57BL; Micelles; Nanoparticles; Ophthalmic Solutions; Protein Kinase Inhibitors; Rabbits; Re-Epithelialization; Signal Transduction; Wound Healing | 2021 |
Evaluation of anti-diabetic activity of glycyrrhizin-loaded nanoparticles in nicotinamide-streptozotocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Delivery Systems; Drug Liberation; Female; Glycyrrhizic Acid; Hypoglycemic Agents; Nanoparticles; Niacinamide; Rats, Wistar; Streptozocin | 2017 |
Glycyrrhizic acid increases glucagon like peptide-1 secretion via TGR5 activation in type 1-like diabetic rats.
Topics: Animals; Blood Glucose; CHO Cells; Cricetinae; Cricetulus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucagon-Like Peptide 1; Glycyrrhizic Acid; Intestinal Mucosa; Male; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled | 2017 |
High Mobility Group Box1 Inhibitor Glycyrrhizic Acid Attenuates Kidney Injury in Streptozotocin-Induced Diabetic Rats.
Topics: Animals; Diabetes Mellitus, Experimental; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Kidney; MAP Kinase Signaling System; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Rats; Receptor for Advanced Glycation End Products; Streptozocin; Toll-Like Receptor 4 | 2017 |
Glycyrrhizic acid suppresses inflammation and reduces the increased glucose levels induced by the combination of Porphyromonas gulae and ligature placement in diabetic model mice.
Topics: Animals; Anti-Inflammatory Agents; Bacteroidaceae Infections; Blood Glucose; Cells, Cultured; Cytokines; Diabetes Mellitus, Experimental; Fibroblasts; Gingiva; Glycyrrhizic Acid; HMGB1 Protein; Hypoglycemic Agents; Male; Mice; Periodontitis; Porphyromonas | 2019 |
Antidiabetic activity enhancement in streptozotocin + nicotinamide-induced diabetic rats through combinational polymeric nanoformulation.
Topics: Animals; Benzoquinones; Blood Glucose; Body Weight; Calorimetry, Differential Scanning; Diabetes Mellitus, Experimental; Drug Compounding; Female; Glycated Hemoglobin; Glycyrrhizic Acid; Hypoglycemic Agents; Lipids; Nanoparticles; Niacinamide; Polymers; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Streptozocin | 2019 |
Glycyrrhizic acid attenuated glycative stress in kidney of diabetic mice through enhancing glyoxalase pathway.
Topics: Aldehyde Reductase; Animals; Chemokine CCL2; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fructose; Glutathione; Glycyrrhizic Acid; Intercellular Adhesion Molecule-1; Kidney; L-Iditol 2-Dehydrogenase; Lactoylglutathione Lyase; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Sorbitol; Thiolester Hydrolases | 2014 |
The proinflammatory cytokine high-mobility group box-1 mediates retinal neuropathy induced by diabetes.
Topics: Animals; Cytokines; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glutamate-Ammonia Ligase; Glycyrrhizic Acid; HMGB1 Protein; Inflammation; Lactoylglutathione Lyase; Male; Rats; Rats, Sprague-Dawley; Retina; Synaptophysin; Tyrosine 3-Monooxygenase | 2014 |
High-Mobility Group Box-1 Modulates the Expression of Inflammatory and Angiogenic Signaling Pathways in Diabetic Retina.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Chemokine CXCL12; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelium, Vascular; Glycyrrhizic Acid; HMGB1 Protein; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoprecipitation; Intravitreal Injections; Male; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, CXCR4; Retinal Vessels; RNA, Messenger; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2015 |
Mutual enhancement between high-mobility group box-1 and NADPH oxidase-derived reactive oxygen species mediates diabetes-induced upregulation of retinal apoptotic markers.
Topics: Acetophenones; Animals; Apoptosis; Biomarkers; Caspase 3; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glycyrrhizic Acid; HMGB1 Protein; Humans; Interleukin-1beta; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Carbonylation; Protein Transport; Rats, Sprague-Dawley; Reactive Oxygen Species; Retina; Up-Regulation; Vitreous Body | 2015 |
Diabetes-Induced Oxidative Stress in Endothelial Progenitor Cells May Be Sustained by a Positive Feedback Loop Involving High Mobility Group Box-1.
Topics: Acetylcysteine; Animals; Blood Glucose; Body Weight; Bone Marrow Cells; Cells, Cultured; Diabetes Mellitus, Experimental; Endothelial Progenitor Cells; Feedback, Physiological; Glycation End Products, Advanced; Glycyrrhizic Acid; HMGB1 Protein; Male; Mice, Inbred C57BL; Models, Biological; Monocytes; Oxidative Stress; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Up-Regulation | 2016 |
High-Mobility Group Box-1 Protein Mediates the Regulation of Signal Transducer and Activator of Transcription-3 in the Diabetic Retina and in Human Retinal Müller Cells.
Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Ependymoglial Cells; Glycyrrhizic Acid; HMGB1 Protein; Humans; Rats; Rats, Sprague-Dawley; Retina; Signal Transduction; STAT3 Transcription Factor | 2017 |
Antihyperglycemic effect of 18 beta-glycyrrhetinic acid, aglycone of glycyrrhizin, on streptozotocin-diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hypolipidemic Agents; Male; Rats; Rats, Wistar; Streptozocin; Time Factors | 2009 |
Ameliorative effects of glycyrrhizin on streptozotocin-induced diabetes in rats.
Topics: Animals; Blood Glucose; Catalase; Cholesterol; Diabetes Mellitus, Experimental; Free Radicals; Fructosamine; Glucose Intolerance; Glyburide; Glycated Hemoglobin; Glycyrrhizic Acid; Hemoglobins; Hyperglycemia; Hyperlipidemias; Insulin; Islets of Langerhans; Kidney; Male; Malondialdehyde; Oxidative Stress; Pancreas; Rats; Rats, Wistar; Superoxide Dismutase | 2011 |
High-mobility group box-1 protein activates inflammatory signaling pathway components and disrupts retinal vascular-barrier in the diabetic retina.
Topics: Animals; Anti-Inflammatory Agents; Blood-Retinal Barrier; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electric Impedance; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Glycyrrhizic Acid; HMGB1 Protein; Immunohistochemistry; Immunoprecipitation; Intercellular Adhesion Molecule-1; Intravitreal Injections; Male; MAP Kinase Signaling System; NF-kappa B; Occludin; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Signal Transduction; Toll-Like Receptor 2 | 2013 |
Effects of 18alpha-glycyrrhizin on the pharmacodynamics and pharmacokinetics of glibenclamide in alloxan-induced diabetic rats.
Topics: Animals; Cytochrome P-450 CYP3A; Diabetes Mellitus, Experimental; Drug Interactions; Glyburide; Glycyrrhizic Acid; Half-Life; Hypoglycemic Agents; Immunohistochemistry; Insulin; Insulin Resistance; Liver Glycogen; Male; Rats; Rats, Wistar | 2008 |