Page last updated: 2024-08-21

glycopyrrolate and Airflow Obstruction, Chronic

glycopyrrolate has been researched along with Airflow Obstruction, Chronic in 254 studies

Research

Studies (254)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's187 (73.62)24.3611
2020's67 (26.38)2.80

Authors

AuthorsStudies
Kato, C; Nakamura, N; Sasajima, T; Yoshisue, H1
Alessandri, M; Cresti, A; Lacerenza, LG; Lena, F; Montagnani, A; Perrella, A; Petrucci, E; Ricci, A; Rogliani, P; Scala, R; Scalese, M; Serafini, A; Sposato, B1
Niu, X; Sanjar, S; Sharma, S; Tashkin, DP1
Bougard, N; Louis, G; Louis, R; Pétré, B; Schleich, F1
Bonhomme, O; Corhay, JL; Heinen, V; Louis, R; Nguyen, D; Van Cauwenberge, H1
He, X; Liu, J; Wu, J1
Chan, MC; Chen, NH; Cheng, SL; Hsieh, MJ; Hsu, WH; Kuo, PH; Lin, MS; Liu, CL; Liu, SF; Tao, CW; Tsai, YH; Wei, YF; Wu, YK; Yang, TM1
Dorinsky, P; Jenkins, M; Krüll, M; Martinez, FJ; Patel, M; Rabe, KF; Singh, D1
Enomoto, N; Fujisawa, T; Furuhashi, K; Hozumi, H; Ikegami, K; Inoue, Y; Inui, N; Kamiya, C; Kamiya, Y; Karayama, M; Katsumata, M; Maekawa, M; Nakamura, Y; Setou, M; Suda, T; Suzuki, Y; Tanaka, Y; Watanabe, H1
Effendi, WI; Emoto, N; Hazama, D; Katsurada, N; Kobayashi, K; Nagano, T; Nishimura, Y; Ryanto, GRT; Suraya, R; Tachihara, M; Yamamoto, M1
Agarwal, J; Compton, C; Czira, A; Dong, X; Duarte, M; Haeussler, K; Halpin, DMG; Ismaila, AS; Malmenäs, M; Nassim, M; Shen, Y; Tongbram, V; Vogelmeier, CF; Živković-Gojović, M1
Arjomandi, M; Barjaktarevic, IZ; Brown, SA; Buhr, RG; Comellas, AP; Cooper, CB; Criner, GJ; Dransfield, MT; Drescher, F; Folz, RJ; Han, MK; Hansel, NN; Kalhan, R; Kaner, RJ; Kanner, RE; Krishnan, JA; Lazarus, SC; Maddipati, V; Martinez, FJ; Mathews, A; McEvoy, C; Meldrum, C; Nyunoya, T; Rogers, L; Sciurba, FC; Stringer, WW; Wang, D; Wendt, CH; White, E; Wise, RA; Wisniewski, SR; Woodruff, PG; Ye, W1
Guo, M; Li, Z; Yu, C1
Bouhaddi, M; Clairet, AL; Degano, B; Diallo, K; Elhage, S; Laurent, L; Puyraveau, M; Ritter, O; Soumagne, T1
Aceituno, S; Baloira, A; Calvo, A; Garin, N; Martínez, A; Prades, M; Torres, C; Touron, C; Trigueros, JA1
Brighton, N; de Nigris, E; Haughney, J; Holmgren, U; Treharne, C; Walker, A1
Aurivillius, M; Bafadhel, M; Darken, P; Dorinsky, P; Jenkins, M; Martinez, FJ; Patel, M; Rabe, KF; Singh, D1
Barjaktarevic, I; Hanania, NA; Mahler, DA; Make, B; Mintz, M; Skolnik, N; Yawn, B; Zeyzus-Johns, B1
Figueira-Gonçalves, JM; Golpe, R; Guanche-Dorta, S; Ramallo-Fariña, Y; Wangüemert-Pérez, AL1
Avorn, J; Feldman, WB; Gagne, JJ; Kesselheim, AS1
Dell'Aniello, S; Ernst, P; Li, J; Suissa, S1
Arslan, B; Çetin, GP; Yilmaz, İ1
Gong, Y; Li, L; Lv, Y; Sui, Z; Zheng, Q1
Banks, V; Castillo, C; Compton, C; Czira, A; Herth, FJF; Ismaila, AS; Quint, JK; Requena, G; Rothnie, KJ; Tritton, T; Wild, R; Wood, R; Yeap, J1
Bates, JHT; Cortellini, M; De Backer, W; Galkin, D; Georges, G; Guasconi, A; Lavon, BR; Panni, I; Skloot, GS1
Agatep, B; Edwards, D; Feigler, N; Lewing, B; Patel, S; Pollack, M; Portillo, E; Schinkel, J; Strange, C; Swisher, S; Tkacz, J; Touchette, DR1
Singh, D2
Calzetta, L; Cazzola, M; Facciolo, F; Matera, MG; Page, C; Rogliani, P1
Darken, P; DeAngelis, K; Dorinsky, P; Dunn, LJ; Gillen, M; Kerwin, EM1
Aurivillius, M; Ballal, S; Bourne, E; DeAngelis, K; Dorinsky, P; Ferguson, GT; Fukushima, Y; Hataji, O; Hayashi, N; Ichinose, M; Inoue, Y; Okada, H; Rabe, KF; Reisner, C; Takikawa, M1
Ascuntar, C; Aviles, S; Benavides-Cordoba, V; Mosquera, R; Orozco, L; Rivera, J1
Assam, PN; Chen, R; Huang, J; Maes, A; Martin, UJ; Mei, X; Qin, Z; Reisner, C; Siddiqui, S; Wang, HY; Zhao, L; Zhong, N1
Arora, S; Jenkins, M; Lipworth, BJ; Martin, UJ; Martinez, FJ; Rabe, KF; Reisner, C1
Alcazar, B; Barrecheguren, M; Kostikas, K; Mezzi, K; Miravitlles, M; Shen, S; Soler-Cataluña, JJ; Wedzicha, JA1
Speer, G; Tamási, L1
Assam, PN; Ballal, S; Bourne, E; Chen, R; DeAngelis, K; Dorinsky, P; He, H; Kang, J; Su, R; Wang, C; Yang, T; Zhao, L1
Assam, PN; Jenkins, M; Lipworth, BJ; Wang, L; Xu, JF; Zheng, J1
Banerji, D; Frent, SM; Gupta, P; Kostikas, K; Mackay, AJ; Olsson, P; Patalano, F; Pfister, P; Roche, N; Wedzicha, JA1
Attri, S; Ballal, S; Darken, P; de Nigris, E; Ferguson, GT; Holmgren, U; Siddiqui, MK; Singh, B1
Donohue, JF; Goodin, T; Ozol-Godfrey, A; Sanjar, S1
Danyliv, A; Gutzwiller, FS; Lakhotia, B; Mahon, R; Nikolaev, I; Thokala, P1
Goodin, T; Ohar, JA; Ozol-Godfrey, A; Sanjar, S1
Collier, DJ; Feldman, GJ; Ferguson, GT; Jenkins, M; Lipworth, BJ; Martinez, FJ; O'Brien, G; Rabe, KF; Reisner, C; Sethi, S1
Aurivillius, M; Ballal, S; Darken, P; Dorinsky, P; Ferguson, GT; Martinez, FJ; McLaren, J; Rabe, KF; Reisner, C; Singh, D; St Rose, E; Trivedi, R; Wang, C; Wedzicha, JA1
Beier, J; Friedrich, FW; Plate, T1
Caldwell-Tarr, A; Conto, RM; Dembek, C; Kerwin, EM; Paullin, M; Stephenson, JJ1
Bourdin, A; Cazorla, O; Charriot, J; Grillet, PE; Le Souder, C; Rohou, J1
Plunkett, C1
Banerji, D; Frent, SM; Gupta, P; Kostikas, K; Mackay, AJ; Patalano, F; Pfister, PJ; Vogelmeier, CF; Wedzicha, JA1
Carpaij, OA; Kerstjens, HAM; Niemeijer, A; Seigers, D; van Geffen, WH; Vonk, JM; Westbroek, LF1
Gon, Y; Hayashi, N; Hirata, H; Maes, A; Martin, UJ; Nishi, K; Reisner, C; Sato, K; Siddiqui, S1
Assam, PN; Dorinsky, P; Feng, C; Gillen, M; Huang, Y; Su, R1
Calverley, P1
Darken, P; Dorinsky, P; Martinez, FJ1
Fernández-Villar, A; López-Campos, JL; Ruano-Ravina, A1
Calzetta, L; Rogliani, P1
Beaudot, C; De La Cruz, L; Edwards, M; Feldman, G; Georges, G; Kerwin, E; Pearle, J1
Marth, K; Pohl, W; Renner, A1
Bourdin, A; De Nigris, E; Ferguson, GT; Holmgren, U; Jenkins, M; Molinari, N; Ouwens, M; Siddiqui, MK; Singh, B1
Cheng, SH; Hsu, YJ; Huang, YL; Lai, JH; Lin, CW; Liou, JT; Pan, HY; Tsai, CL; Wang, MT1
Bartels, C; Jain, M; Tillmann, HC; Vaidya, S; Yu, J1
Aritake, H; Gamo, S; Ichinose, M; Kazama, I; Murakami, K; Nara, M; Sugiura, H; Tamada, T1
Elzinga, CRS; Han, B; Maarsingh, H; Meurs, H; Oldenburger, A; Schmidt, M; Sopi, RB; Timens, W; Zuidhof, AB1
Aurivillius, M; De Backer, J; De Backer, W; Dorinsky, P; Jenkins, M; Trivedi, R; van den Berge, M; Van Holsbeke, C1
Gallo, O; Mangia, PP; Pradelli, L; Ritrovato, D1
Heo, YA1
Nigro, SC; Sobieraj, DM1
Abo, M; Hara, J; Kasahara, K; Kimura, H; Nishikawa, S; Ogawa, N; Ohkura, N; Sone, T; Tambo, Y; Tanaka, R; Watanabe, S1
Corhay, JL1
Blazhko, V; Cohuet, G; Corradi, M; Francisco, C; Montagna, I; Papi, A; Scuri, M; Singh, D; Vestbo, J; Vezzoli, S1
Ficker, JH; Rabe, KF; Welte, T1
Denenberg, M; Donohue, JF; Hanania, NA; Kerwin, EM; Maes, A; O'Donnell, DE; Orevillo, C; Quinn, D; Reisner, C; Siddiqui, S; Tashkin, DP1
Rabe, KF1
Banerji, D; Fogel, R; Fucile, S; Kostikas, K; Mezzi, K; Shen, S; Tsiligianni, I1
Ciciliani, AM; Langguth, P; Wachtel, H1
Aalamian-Mattheis, M; Castellani, W; Clemens, A; Gaga, M; Greulich, T; Kostikas, K; Lane, S; Marin, JM; Ninane, V; Nunez, X; Patalano, F; Vogelmeier, CF1
Darken, P; Fabbri, LM; Ferguson, GT; Martin, UJ; Martinez, FJ; Orevillo, C; Reisner, C1
Acerbi, D; Collarini, S; Mariotti, F; Muraro, A; Scuri, M; Singh, D; Vezzoli, S1
Ellingson, S; Self, TH1
Criner, GJ; Dhungana, S1
Arora, S; Delacruz, L; Fakih, F; Feldman, G; Gottschlich, G; Koser, A; Krainson, J; Maes, A; Martin, U; Orevillo, C; Pudi, K; Reisner, C; Siddiqui, S; St Rose, E1
Cazzola, M; Rogliani, P1
Ferguson, GT; Goodin, T; Kerwin, E; Tosiello, R; Wheeler, A1
Pong, CK1
Buhl, R; Criée, CP; Kardos, P; Lossi, NS; Vogelmeier, CF; Worth, H1
Ayers, T; Banerji, D; Ferguson, GT; Fogel, R; Goodin, T; Kerwin, E; Maitra, S; Sanjar, S; Sen, B; Yadao, A1
Doty, A; Flynn, B; Lechuga-Ballesteros, D; Mack, P; Schroeder, J; Sommerville, M; Taylor, M; Vang, K1
Corradi, M; Papi, A; Petruzzelli, S; Scuri, M; Singh, D; Spinola, M; Usmani, OS; Vestbo, J1
Banerji, D; Fogel, R; Patalano, F1
Physicians From Medical Centers In Poland, GO; Płusa, T1
Bauer, A; Ferguson, GT; Goodin, T; Kerwin, E; Pham, S; Wheeler, A1
Hida, N; Hizawa, N; Nakaizumi, T; Satoh, H; Terashima, H; Yamada, H1
Cristiano, A; Radovanovic, D; Rizzi, M; Santus, P; Valenti, V1
Donohue, JF; Goodin, T; Tosiello, R; Wheeler, A1
Deas, SD; Huprikar, N1
Bjermer, L; Costa-Scharplatz, M; Gutzwiller, FS; Keininger, DL; Lisspers, K; Mahon, R; Olsson, P; Roche, N; van Boven, JFM1
Calzetta, L; Cavalli, F; Cazzola, M; Matera, MG; Ora, J; Puxeddu, E; Rogliani, P1
Cohuet, G; Corradi, M; Fabbri, L; Guasconi, A; Montagna, I; Papi, A; Petruzzelli, S; Prunier, H; Roche, N; Scuri, M; Singh, D; Vestbo, J; Vezzoli, S1
Kerwin, EM; Kollar, C; Reisner, C; Spangenthal, S; St Rose, E1
Burke, C; Chow, WL; Guruprasad, B; Tee, A1
Ferguson, GT; Maes, A; Martin, UJ; Reisner, C; Rodriguez-Roisin, R; Siddiqui, S1
Aalamian-Mattheis, M; Clemens, A; Fogel, R; Kostikas, K; Nunez, X; Pagano, VA; Patalano, F1
Ferguson, GT; Kerwin, E1
Banerji, D; Chapman, KR; Fogel, R; Frent, SM; Goyal, P; Guerin, T; Hurst, JR; Kostikas, K; Larbig, M; Patalano, F; Pfister, P; Wedzicha, JA1
Altman, P; Bader, G; D'Urzo, A; Goyal, P; Shen, S1
Beeh, KM; Emirova, A; Nandeuil, MA; Prunier, H; Santoro, D1
Iwakura, M; Satake, M; Sato, S; Shioya, T; Takahashi, H; Terui, Y; Uemura, S1
Anzueto, AR; Banerji, D; Fogel, R; Kostikas, K; Larbig, M; Mezzi, K; Patalano, F; Shen, S; Wedzicha, JA1
Gross, NJ; Tashkin, DP1
Darken, P; Kerwin, EM; Pearle, J; Reisner, C; Rose, ES1
Banerji, D; Chapman, KR; Fogel, R; Frent, SM; Gutzwiller, FS; Kostikas, K; Larbig, M; Mackay, A; Patalano, F; Shen, S; Wedzicha, JA1
Ashmawi, S; Backer, A; Diaz, DV; Frith, PA; Gurgun, A; Hamann, AM; Hristoskova, S; Kostikas, K; Krishnamurthy, S; Olsson, P; Pilipovic, V1
Blasi, F; Mantero, M; Radovanovic, D; Santus, P1
Pleasants, RA1
Clukers, J; De Backer, J; De Backer, W; Hajian, B; Jenkins, M; Martin, UJ; Reisner, C; Siddiqui, S; Van Holsbeke, C; Verlinden, I; Vos, W1
Bafadhel, M1
Fakih, F; Feldman, G; Mack, P; Maes, A; Pudi, K; Reisner, C; Siddiqui, S; St Rose, E1
Donohue, JF; Ferguson, GT; Ganapathy, V; Kerwin, EM; Ozol-Godfrey, A; Rajagopalan, K1
Kuna, P; Kupczyk, M1
Kasak, V; Klimes, J; Skoupa, J; Valena, T1
Fogel, R; Fucile, S; Goyal, P; Jenkins, C; Kostikas, K; Mezzi, K; Shen, S; Singh, D; Tsiligianni, I; Wedzicha, JA1
Bentivenga, C; Berardi, E; Borghi, C; Bui, V; Cicero, AF; Cosentino, ER; Esposti, DD; Landolfo, M; Miceli, R; Spinardi, L1
Lad, R; Rhee, CK; Yoshisue, H1
Corradi, M; Fabbri, LM; Georges, G; Guasconi, A; Papi, A; Petruzzelli, S; Singh, D; Vezzoli, S1
Abels, C; Chabicovsky, M; Kilic, A; Masur, C; Soeberdt, M; Winkler, S1
Dorman, J; Kelly, K; Lacey, S; McGrath, K; Molony, D; O'Doherty, B; Schmid, S; Sullivan, S; Whelan, S1
Douglas, M1
Bourdin, A; Deslee, G; Feldman, GJ; Ferguson, GT; Fjällbrant, H; Jenkins, MA; Maltais, F; Martin, UJ; Siwek-Posłuszna, A1
Bowling, A; Goodin, T; Ozol-Godfrey, A; Price, B; Sanjar, S; Sharma, S; Tashkin, DP1
DeAngelis, K; Dorinsky, P; Ferguson, GT; Kerwin, EM; Mo, M1
Bartels, C; Kaiser, G; Looby, M; Sechaud, R1
Carter, NJ1
Wise, J1
Alagappan, VK; Banerji, D; Chapman, KR; Chen, H; Dahl, R; Kho, P; Mehta, R; Rudolf, M1
Schachter, EN1
D'Andrea, P; Molimard, M1
Ulrik, CS6
Thompson, H1
Greening, A; Huisman, E; Karabis, A; Lindner, L; Mocarski, M1
Baldwin, M; Buckley, F; Capkun-Niggli, G; Cope, S; Donohue, JF; Ellis, A; Jansen, JP; Jones, P; Kraemer, M1
Hiratsuka, M; Kozawa, M; Nakanishi, M; Yoshisue, H1
Alagappan, VK; Banerji, D; Chen, H; Dahl, R; Jadayel, D1
Alagappan, VK; Banerji, D; Chen, H; D'Urzo, A; Decramer, M; Gallagher, N; Kulich, K; Mahler, DA; White, T; Worth, H1
Beeh, KM1
Antoniu, S; Râjnoveanu, RM; Ulmeanu, R1
Tashkin, DP1
Alagappan, VK; Banerji, D; Bateman, ED; Chen, H; D'Andrea, P; Pallante, J; Vogelmeier, CF1
Chen, XP; Dong, XW; Jia, YL; Jin, F; Liu, YN; Shen, HJ; Shen, LL; Sun, Y; Wen, C; Xie, QM1
Han, MK1
Arrasate, C; Banerji, D; Chen, H; D'Andrea, P; Decramer, M; Ficker, JH; Niewoehner, DE; Sandström, T; Taylor, AF; Wedzicha, JA2
Yaqub, F1
Van Meerhaeghe, A; Vanhaeverbeek, M1
Bateman, ED; Beeh, KM; Beier, J; Chapman, KR; Chen, H; D'Andrea, P; D'Urzo, A; Henley, M; Nutbrown, R; Overend, T1
Peeters, S; Warnez, M1
Banerji, D; Beeh, KM; Beier, J; D'Andrea, P; Henley, M; Jadayel, D; Korn, S1
Plaza, V; Rodrigo, GJ1
Aumann, J; Chen, H; Goyal, P; Henley, M; McBryan, D; Vincken, W1
Frampton, JE1
Banerji, D; Bateman, ED; Mahler, DA; Patalano, F; Vogelmeier, CF; Wedzicha, JA1
Darken, P; Fernandez, C; Fischer, T; Fogarty, C; Golden, M; Orevillo, C; Reisner, C; Rennard, S; Rose, ES; Tardie, G1
Banerji, D; Buhl, R; Chen, H; D'Andrea, P; Dahl, R; Fogel, R; Schubert-Tennigkeit, A; Wedzicha, JA1
Calzetta, L; Cazzola, M; Facciolo, F; Matera, MG; Rogliani, P; Segreti, A1
Barnes, PJ; Jones, CR; Leaker, BR; Singh, D; Tutuncu, A1
Asukai, Y; Costa-Scharplatz, M; Dimova, M; Keininger, D; Mezzi, K; Price, D; Ställberg, B1
Cazzola, M; Matera, MG; Rogliani, P2
Maselli, R; Matera, MG; Pelaia, G1
Incorvaia, C; Riario-Sforza, E; Riario-Sforza, GG; Ridolo, E2
Buhl, R; Criée, CP; Kardos, P; Vogelmeier, C; Worth, H1
Bai, L; D'Andrea, P; Firth, R; Huang, Y; Humphries, M; Kho, P; Li, L; Sun, T; Wang, C; Wang, Q1
Babu, KS; Morjaria, JB; Prakash, A1
Buhl, R; Foerster, K; Gessner, C; Hiltl, S; Korn, S; Schuermann, W; Sieder, C1
Baroni, M; Incorvaia, C; Montagni, M; Riario-Sforza, GG; Ridolo, E1
Kozielski, J1
Jones, PW1
Bremner, P; Chang, CL; Day, P; Frenzel, C; Frith, PA; Kurstjens, N; Ratnavadivel, R; Thompson, PJ1
Calzetta, L; Cazzola, M; Lipsi, R; Matera, MG; Ora, J; Rogliani, P; Segreti, A1
Horita, N; Kaneko, T1
Banerji, D; Humphries, M; Patalano, F; Thach, C; Wang, C; Wang, L; Zhang, N; Zhong, N; Zhou, X1
Lipworth, B1
Ayers, T; Banerji, D; FowlerTaylor, A; Kerwin, E; Lloyd, M; Mahler, DA; Maitra, S; Patalano, F; Thach, C1
Nagy, LB1
Cazzola, M; Poletti, V; Rossi, A; Zanardi, E1
Hubert, M2
Altman, P; Chapman, KR; D'Andrea, P; D'Urzo, AD; Decramer, M; DiGiovanni, R; Goyal, P; Hu, H; Kerwin, EM1
Asukai, Y; Costa-Scharplatz, M; Goyal, P; Gruenberger, JB; Price, D; Ställberg, B1
Cockle, SM; Huisman, EL; Ismaila, AS; Karabis, A; Punekar, YS1
Lindberg, M1
Donohue, JF2
Centanni, S; Di Marco, F; Raccanelli, R; Radovanovic, D; Santus, P; Valenti, V1
Disse, B; Hallmann, C; Metzdorf, N1
Huisman, EL; Ismaila, AS; Karabis, A; Punekar, YS1
Buck, H; Down, G; O'Connor, G; Ravi, A; Reid, F; Singh, D1
Einecke, D3
Bartels, C; Bieth, B; Demin, I; Gautier, A; Graham, G; Sechaud, R; Tillmann, HC1
Anzueto, A; Halpin, DM; Metzdorf, N; Pieper, MP; Richard, F; Vogelmeier, C1
Bonnet-Gonod, F; Cohuet, G; Hoffmann, M; Muraro, A; Petruzzelli, S; Schröder-Babo, W; Siergiejko, Z; Singh, D1
Ayers, RT; Banerji, D; Chapman, KR; Fogel, R; Patalano, F; Roche, N; Thach, C; Vestbo, J; Vogelmeier, CF; Wedzicha, JA1
Banerjee, R; D'Andrea, P; Eckert, JH; Gifford, AH; Jessop, N; Mahler, DA; Mota, F; Satti, A1
Kuwahira, I1
Al-Majed, NS; Chiu, MH; Pollmann, D; Sandhu, RK; Stubbins, R1
Baier, M; Kirsten, A; Mailänder, C; Watz, H1
D'Andrea, P; Eckert, JH; Feldman, G; Henley, M; LaForce, C; Patalano, F; Spangenthal, S1
Fernández-Villar, A; Leiro-Fernández, V; Priegue Carrera, A1
Aalamian-Mattheis, M; Beeh, KM; Casamor, R; Castellani, W; Clemens, A; Gunstone, A; Kostikas, K; Marin, JM; Saralaya, D; Schaper, L1
Carrasco, J; Chehab, S; Gruenberger, JB; Keininger, DL; Molimard, M; Pitotti, C; Price, D; Reza Maleki-Yazdi, M; Sauvage, E1
Aliberti, S; Di Marco, F; Mantero, M; Radovanovic, D; Santus, P; Sferrazza Papa, GF; Valenti, V1
Banerji, D; Vogelmeier, CF; Wedzicha, JA1
Suissa, S1
Franssen, FM; Vanfleteren, LE; Wouters, EF1
Contoli, M; Morelli, P; Papi, A1
Darken, P; Dwivedi, S; Fabbri, LM; Ferguson, GT; Fischer, T; Golden, M; Kerwin, EM; Orevillo, C; Pearle, J; Reisner, C; Rodriguez-Roisin, R; Sethi, S; Spangenthal, S; St Rose, E1
Ito, YM; Kanda, R; Konno, S; Makita, H; Nakano, Y; Nishimura, M; Ogawa, E; Seto, R; Shimizu, K; Suzuki, M1
Darken, P; Denenberg, M; Donohue, JF; Fischer, T; Fogarty, C; Golden, M; Gotfried, M; Gottschlich, G; Martinez, FJ; Orevillo, C; Reisner, C; Rodriguez-Roisin, R; St Rose, E; Strom, S; Tashkin, DP1
Arora, S; Darken, P; Fabbri, LM; Feldman, GJ; Ferguson, GT; Fischer, T; Golden, M; Gottschlich, GM; Maes, A; Martinez, FJ; Orevillo, C; Rabe, KF; Reisner, C; Rennard, S; Rodriguez-Roisin, R; Sethi, S; Siddiqui, S; Siler, TM; Spangenthal, S1
Baier, M; Kirsten, AM; Mailänder, C; May, C; Watz, H1
Bader, G; Banerji, D; Fogel, R; Humphries, MJ; Mezzi, K; Patalano, F; Vogelmeier, C; Zhong, N1
Darken, P; Donohue, JF; Dwivedi, S; Fabbri, LM; Ferguson, GT; Fischer, T; Fogarty, C; Golden, M; Kerwin, EM; Martinez, FJ; Orevillo, C; Rabe, KF; Reisner, C; Spangenthal, S; St Rose, E; Strom, S1
Azzola, A; Brutsche, M; Clemens, A; Domenighetti, G; Fitting, JW; Frey, JG; Geiser, T; Kostikas, K; Salomon, J; Schmidt, U; Sigrist, T; Stolz, D; Turk, AJ; Wild, C1
Hwang, YI; Jung, JY; Jung, KS; Kim, S; Kim, TH; Lee, JH; Lee, SW; Park, HY; Park, JW; Rhee, CK1
Kadoya, K; Kaga, N; Liu, X; Nagahama, KY; Namba, Y; Orimo, A; Taka, H; Takahashi, K; Togo, S; Tulafu, M1
Cheung, D; Galdiz, JB; Güçlü, SZ; Henley, M; Mizutani, G; Overend, T; Spangenthal, S; Verkindre, C; Vogelmeier, C; Zeldin, RK1
Dolker, M; Flémale, A; Fukuchi, Y; Overend, T; Prasad, N; Takeda, A; Verkindre, C1
Buhl, R; Dolker, M; Jones, F; Laforce, C; Martin, C; Overend, T; van Noord, JA1
Di Scala, L; Drollmann, A; Fogarty, C; Hattersley, H1
Dolker, M; Fabbri, LM; Horton, R; Martin, C; Overend, T; Van de Maele, B1
Koshika, T; Niiya, R; Ogoda, M; Yamada, S1
Banerji, D; Vogelmeier, C1
Banerji, D; D'Urzo, A; Ferguson, GT; Hirata, K; Horton, R; Lu, Y; Martin, C; Overend, T; van Noord, JA1
Drollmann, A; Kaiser, G; Motte, Sde L; Renard, D; Sechaud, R; Zhang-Auberson, L1
Beeh, KM; Di Scala, L; Drollmann, A; Singh, D1
Alagappan, VK; Banerji, D; Gallagher, N; Hébert, J; Kerwin, E; Lu, Y; Martin, C; Overend, T1
Banerji, D; Buhl, R1
Alagappan, V; Arievich, H; Banerji, D; Gibbs, M; Looby, M; Overend, T; Renard, D1

Reviews

61 review(s) available for glycopyrrolate and Airflow Obstruction, Chronic

ArticleYear
Impact of baseline clinical features on outcomes of nebulized glycopyrrolate therapy in COPD.
    NPJ primary care respiratory medicine, 2021, 10-07, Volume: 31, Issue:1

    Topics: Administration, Inhalation; Bronchodilator Agents; Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2021
Economic Evaluation of Triple Therapy with Budesonide/Glycopyrrolate/Formoterol Fumarate for the Treatment of Moderate to Very Severe Chronic Obstructive Pulmonary Disease in China Using a Semi-Markov Model.
    Applied health economics and health policy, 2022, Volume: 20, Issue:5

    Topics: Administration, Inhalation; Bronchodilator Agents; Budesonide; Clinical Studies as Topic; Cost-Benefit Analysis; Drug Combinations; Formoterol Fumarate; Fumarates; Glycopyrrolate; Humans; Metered Dose Inhalers; Pulmonary Disease, Chronic Obstructive

2022
Comparative Efficacy of Umeclidinium/Vilanterol Versus Other Bronchodilators for the Treatment of Chronic Obstructive Pulmonary Disease: A Network Meta-Analysis.
    Advances in therapy, 2022, Volume: 39, Issue:11

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Benzyl Alcohols; Bronchodilator Agents; Chlorobenzenes; Drug Combinations; Dyspnea; Forced Expiratory Volume; Glycopyrrolate; Humans; Muscarinic Antagonists; Network Meta-Analysis; Pulmonary Disease, Chronic Obstructive; Quinuclidines; Salmeterol Xinafoate; Tiotropium Bromide; Treatment Outcome

2022
The Efficacy and Safety of Budesonide/Glycopyrronium/Formoterol in the Treatment of COPD in the Elderly.
    Contrast media & molecular imaging, 2022, Volume: 2022

    Topics: Aged; Bronchodilator Agents; Budesonide; Drug Combinations; Formoterol Fumarate; Glycopyrrolate; Humans; Pulmonary Disease, Chronic Obstructive

2022
Reducing the Risk of Mortality in Chronic Obstructive Pulmonary Disease With Pharmacotherapy: A Narrative Review.
    Mayo Clinic proceedings, 2023, Volume: 98, Issue:2

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Bronchodilator Agents; COVID-19; Drug Therapy, Combination; Formoterol Fumarate; Glycopyrrolate; Humans; Pulmonary Disease, Chronic Obstructive

2023
The Role of Long-Acting Antimuscarinic Agents in the Treatment of Asthma.
    Journal of aerosol medicine and pulmonary drug delivery, 2023, Volume: 36, Issue:4

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Asthma; Bronchodilator Agents; Cholinergic Antagonists; Glycopyrrolate; Humans; Inflammation; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Tiotropium Bromide

2023
LABA/LAMA versus LABA/ICS fixed-dose combinations in the prevention of COPD exacerbations: a modeling analysis of literature aggregate data.
    European journal of clinical pharmacology, 2023, Volume: 79, Issue:10

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Drug Combinations; Fluticasone; Formoterol Fumarate; Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2023
Efficacy of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Versus Other Inhaled Corticosteroid/Long-Acting Muscarinic Antagonist/Long-Acting β
    Advances in therapy, 2020, Volume: 37, Issue:6

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Aged; Bayes Theorem; Bronchodilator Agents; Budesonide; Drug Combinations; Dyspnea; Female; Forced Expiratory Volume; Formoterol Fumarate; Fumarates; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Agonists; Muscarinic Antagonists; Network Meta-Analysis; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests; Treatment Outcome

2020
Benefits of glycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI) in improving lung function and reducing exacerbations in patients with moderate-to-very severe COPD: a pooled analysis of the PINNACLE studies.
    Respiratory research, 2020, May-25, Volume: 21, Issue:1

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Clinical Trials, Phase III as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Formoterol Fumarate; Glycopyrrolate; Humans; Lung; Male; Metered Dose Inhalers; Middle Aged; Multicenter Studies as Topic; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Respiratory Function Tests; Severity of Illness Index

2020
Glycopyrrolate and formoterol fumarate for the treatment of COPD.
    Expert review of respiratory medicine, 2021, Volume: 15, Issue:1

    Topics: Administration, Inhalation; Bronchodilator Agents; Formoterol Fumarate; Glycopyrrolate; Humans; Pulmonary Disease, Chronic Obstructive

2021
Efficacy and Safety of Budesonide/Glycopyrronium/Formoterol Fumarate versus Other Triple Combinations in COPD: A Systematic Literature Review and Network Meta-analysis.
    Advances in therapy, 2021, Volume: 38, Issue:6

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Bayes Theorem; Bronchodilator Agents; Budesonide; Drug Combinations; Formoterol Fumarate; Fumarates; Glycopyrrolate; Humans; Muscarinic Antagonists; Network Meta-Analysis; Pulmonary Disease, Chronic Obstructive; Quality of Life

2021
Population Pharmacokinetic Analysis of Indacaterol/Glycopyrronium/Mometasone Furoate After Administration of Combination Therapies Using the Breezhaler
    European journal of drug metabolism and pharmacokinetics, 2021, Volume: 46, Issue:4

    Topics: Administration, Inhalation; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Child; Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Drug Combinations; Female; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Models, Biological; Mometasone Furoate; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Quinolones; Randomized Controlled Trials as Topic; Young Adult

2021
Budesonide/Glycopyrronium/Formoterol: A Review in COPD.
    Drugs, 2021, Volume: 81, Issue:12

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Budesonide; Drug Combinations; Formoterol Fumarate; Glucocorticoids; Glycopyrrolate; Humans; Metered Dose Inhalers; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2021
Budesonide/Glycopyrrolate/Formoterol Fumarate Co-suspension Metered Dose Inhaler: A Triple Therapy for the Treatment of Chronic Obstructive Pulmonary Disease.
    The Annals of pharmacotherapy, 2022, Volume: 56, Issue:5

    Topics: Bronchodilator Agents; Budesonide; Double-Blind Method; Drug Combinations; Formoterol Fumarate; Fumarates; Glycopyrrolate; Humans; Metered Dose Inhalers; Pulmonary Disease, Chronic Obstructive

2022
Role of dual bronchodilators in COPD: A review of the current evidence for indacaterol/glycopyrronium.
    Pulmonary pharmacology & therapeutics, 2017, Volume: 45

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Animals; Bronchodilator Agents; Drug Combinations; Glucocorticoids; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Severity of Illness Index

2017
New Treatment Option for Chronic Obstructive Pulmonary Disease: Two Long-Acting Bronchodilators in a Single Metered-Dose Inhaler.
    The American journal of medicine, 2017, Volume: 130, Issue:11

    Topics: Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Delayed-Action Preparations; Drug Combinations; Formoterol Fumarate; Glycopyrrolate; Humans; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2017
Spotlight on glycopyrronium/formoterol fumarate inhalation aerosol in the management of COPD: design, development, and place in therapy.
    International journal of chronic obstructive pulmonary disease, 2017, Volume: 12

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Disease Progression; Drug Combinations; Forced Expiratory Volume; Formoterol Fumarate; Glycopyrrolate; Humans; Lung; Metered Dose Inhalers; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Time Factors; Treatment Outcome

2017
Comparative effectiveness of indacaterol/glycopyrronium in the treatment of chronic obstructive pulmonary disease.
    Journal of comparative effectiveness research, 2017, Volume: 6, Issue:7

    Topics: Adrenal Cortex Hormones; Bronchodilator Agents; Comparative Effectiveness Research; Drug Combinations; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Observational Studies as Topic; Pulmonary Disease, Chronic Obstructive; Quinolones; Randomized Controlled Trials as Topic; Treatment Outcome

2017
Triple therapy in COPD: new evidence with the extrafine fixed combination of beclomethasone dipropionate, formoterol fumarate, and glycopyrronium bromide.
    International journal of chronic obstructive pulmonary disease, 2017, Volume: 12

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Beclomethasone; Bronchodilator Agents; Disease Progression; Drug Combinations; Evidence-Based Medicine; Exercise Tolerance; Forced Expiratory Volume; Formoterol Fumarate; Glucocorticoids; Glycopyrrolate; Humans; Lung; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Recovery of Function; Risk Factors; Time Factors; Treatment Outcome

2017
Indacaterol/glycopyrronium: a dual bronchodilator for COPD.
    Drug discovery today, 2018, Volume: 23, Issue:1

    Topics: Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Drug Approval; Drug Combinations; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Treatment Outcome

2018
Role of nebulized glycopyrrolate in the treatment of chronic obstructive pulmonary disease.
    Drug design, development and therapy, 2017, Volume: 11

    Topics: Administration, Inhalation; Animals; Glycopyrrolate; Humans; Molecular Structure; Pulmonary Disease, Chronic Obstructive

2017
Dual bronchodilator therapy for chronic obstructive pulmonary disease: evidence for the efficacy and Safety of fixed dose combination treatments in the setting of recent guideline updates.
    Current opinion in pulmonary medicine, 2018, Volume: 24, Issue:2

    Topics: Administration, Inhalation; Benzoxazines; Benzyl Alcohols; Bronchodilator Agents; Chlorobenzenes; Delayed-Action Preparations; Drug Combinations; Formoterol Fumarate; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Practice Guidelines as Topic; Pulmonary Disease, Chronic Obstructive; Quinolones; Quinuclidines; Tiotropium Bromide; Tropanes

2018
An overview of glycopyrrolate/eFlow® CS in COPD.
    Expert review of respiratory medicine, 2018, Volume: 12, Issue:6

    Topics: Clinical Trials as Topic; Glycopyrrolate; Humans; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive

2018
Improvement of physical activity in chronic obstructive pulmonary disease by pulmonary rehabilitation and pharmacological treatment.
    Respiratory investigation, 2018, Volume: 56, Issue:4

    Topics: Adrenergic beta-2 Receptor Agonists; Behavior; Counseling; Delayed-Action Preparations; Drug Therapy, Combination; Energy Metabolism; Exercise; Formoterol Fumarate; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quality of Life; Quinolones; Self Efficacy; Terbutaline; Treatment Outcome; Tropanes

2018
Inhaled glycopyrrolate for the treatment of chronic obstructive pulmonary disease.
    International journal of chronic obstructive pulmonary disease, 2018, Volume: 13

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Europe; Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quality of Life; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Treatment Outcome

2018
Management of severe COPD exacerbations: focus on beclomethasone dipropionate/formoterol/glycopyrronium bromide.
    International journal of chronic obstructive pulmonary disease, 2018, Volume: 13

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Beclomethasone; Bronchodilator Agents; Disease Progression; Drug Therapy, Combination; Formoterol Fumarate; Glucocorticoids; Glycopyrrolate; Humans; Pulmonary Disease, Chronic Obstructive; Quality of Life; Randomized Controlled Trials as Topic

2018
Glycopyrrolate/eFlow CS: The First Nebulized Long-Acting Muscarinic Antagonist Approved to Treat Chronic Obstructive Pulmonary Disease.
    The Annals of pharmacotherapy, 2019, Volume: 53, Issue:3

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Drug Delivery Systems; Female; Glycopyrrolate; Humans; Male; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2019
Beclomethasone dipropionate, formoterol fumarate and glycopyrronium bromide as a combination therapy for chronic obstructive pulmonary disease.
    Expert review of respiratory medicine, 2019, Volume: 13, Issue:1

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Beclomethasone; Bronchodilator Agents; Cholinergic Antagonists; Drug Therapy, Combination; Formoterol Fumarate; Glucocorticoids; Glycopyrrolate; Humans; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive

2019
Fixed-Dose Combinations of Long-Acting Bronchodilators for the Management of COPD: Global and Asian Perspectives.
    Advances in therapy, 2019, Volume: 36, Issue:3

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Asian People; Benzoxazines; Benzyl Alcohols; Bronchodilator Agents; Chlorobenzenes; Drug Combinations; Formoterol Fumarate; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Quinuclidines; Tiotropium Bromide; Treatment Outcome; Tropanes

2019
Pharmacology, toxicology and clinical safety of glycopyrrolate.
    Toxicology and applied pharmacology, 2019, 05-01, Volume: 370

    Topics: Administration, Inhalation; Administration, Oral; Administration, Topical; Animals; Carcinogenicity Tests; Cholinergic Antagonists; Female; Glycopyrrolate; Humans; Hyperhidrosis; Male; Molecular Structure; Mutagenicity Tests; Pulmonary Disease, Chronic Obstructive; Reproduction

2019
Inhaled glycopyrronium bromide: a review of its use in patients with moderate to severe chronic obstructive pulmonary disease.
    Drugs, 2013, Volume: 73, Issue:7

    Topics: Administration, Inhalation; Drug Interactions; Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2013
▾Glycopyrronium for COPD.
    Drug and therapeutics bulletin, 2013, Volume: 51, Issue:6

    Topics: Administration, Inhalation; Bronchodilator Agents; Delayed-Action Preparations; Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2013
Indacaterol/glycopyrronium bromide fixed-dose combination for the treatment of COPD.
    Drugs of today (Barcelona, Spain : 1998), 2013, Volume: 49, Issue:7

    Topics: Adrenergic beta-2 Receptor Agonists; Drug Combinations; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones

2013
Once-daily glycopyrronium via the Breezhaler® device for the treatment of COPD: pharmacological and clinical profile.
    Expert review of clinical pharmacology, 2013, Volume: 6, Issue:5

    Topics: Administration, Inhalation; Animals; Clinical Trials as Topic; Drug Administration Schedule; Dry Powder Inhalers; Glycopyrrolate; Humans; Molecular Structure; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2013
[Glycopyrronium bromide is a long-acting inhaled anticholinergic in the treatment of severe COPD].
    Ugeskrift for laeger, 2013, Aug-26, Volume: 175, Issue:35

    Topics: Administration, Inhalation; Bronchodilator Agents; Delayed-Action Preparations; Forced Expiratory Volume; Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2013
Comparative efficacy of aclidinium versus glycopyrronium and tiotropium, as maintenance treatment of moderate to severe COPD patients: a systematic review and network meta-analysis.
    International journal of chronic obstructive pulmonary disease, 2013, Volume: 8

    Topics: Bayes Theorem; Bronchodilator Agents; Forced Expiratory Volume; Glycopyrrolate; Humans; Lung; Muscarinic Antagonists; Odds Ratio; Pulmonary Disease, Chronic Obstructive; Recovery of Function; Scopolamine Derivatives; Severity of Illness Index; Tiotropium Bromide; Treatment Outcome; Tropanes

2013
Comparative efficacy of long-acting bronchodilators for COPD: a network meta-analysis.
    Respiratory research, 2013, Oct-07, Volume: 14

    Topics: Albuterol; Bayes Theorem; Bronchodilator Agents; Delayed-Action Preparations; Dose-Response Relationship, Drug; Ethanolamines; Formoterol Fumarate; Glycopyrrolate; Humans; Indans; Pulmonary Disease, Chronic Obstructive; Quinolones; Randomized Controlled Trials as Topic; Salmeterol Xinafoate; Scopolamine Derivatives; Severity of Illness Index; Tiotropium Bromide; Treatment Outcome

2013
[New therapeutic choice for COPD: glycopyrronium bromide, a long-acting muscarinic antagonist].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2013, Volume: 142, Issue:4

    Topics: Administration, Inhalation; Animals; Clinical Trials as Topic; Delayed-Action Preparations; Glycopyrrolate; Humans; Muscarinic Antagonists; Protein Binding; Pulmonary Disease, Chronic Obstructive; Receptors, Muscarinic

2013
Efficacy and safety of a fixed-dose combination of indacaterol and Glycopyrronium for the treatment of COPD: a systematic review.
    Chest, 2014, Volume: 146, Issue:2

    Topics: Dose-Response Relationship, Drug; Drug Therapy, Combination; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Practice Guidelines as Topic; Pulmonary Disease, Chronic Obstructive; Quinolones; Randomized Controlled Trials as Topic; Treatment Outcome

2014
QVA149 (indacaterol/glycopyrronium fixed-dose combination): a review of its use in patients with chronic obstructive pulmonary disease.
    Drugs, 2014, Volume: 74, Issue:4

    Topics: Administration, Inhalation; Bronchodilator Agents; Clinical Trials, Phase III as Topic; Drug Combinations; Glycopyrrolate; Humans; Indans; Pulmonary Disease, Chronic Obstructive; Quinolones; Respiratory Function Tests; Severity of Illness Index; Treatment Outcome

2014
Glycopyrronium for inhalation. COPD: another antimuscarinic with cardiac adverse effects that require monitoring.
    Prescrire international, 2014, Volume: 23, Issue:146

    Topics: Administration, Inhalation; Clinical Trials as Topic; Drug Interactions; Electrocardiography; Glycopyrrolate; Heart Diseases; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2014
Clinical benefit of fixed-dose dual bronchodilation with glycopyrronium and indacaterol once daily in patients with chronic obstructive pulmonary disease: a systematic review.
    International journal of chronic obstructive pulmonary disease, 2014, Volume: 9

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Drug Administration Schedule; Drug Combinations; Glycopyrrolate; Humans; Indans; Lung; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Randomized Controlled Trials as Topic; Recovery of Function; Time Factors; Treatment Outcome

2014
Recent advances in COPD disease management with fixed-dose long-acting combination therapies.
    Expert review of respiratory medicine, 2014, Volume: 8, Issue:3

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Albuterol; Benzyl Alcohols; Bronchodilator Agents; Chlorobenzenes; Disease Management; Disease Progression; Drug Combinations; Ethanolamines; Formoterol Fumarate; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Quinuclidines; Salmeterol Xinafoate; Scopolamine Derivatives; Tiotropium Bromide; Treatment Outcome

2014
[The combination of indacaterol and glycopyrronium has effects on symptoms, lung function, and rate of exacerbations in COPD patients].
    Ugeskrift for laeger, 2014, Sep-15, Volume: 176, Issue:38

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Disease Progression; Drug Combinations; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quality of Life; Quinolones

2014
Treatment of chronic obstructive pulmonary disease by dual bronchodilation with coformulation of indacaterol/glycopyrronium.
    Pharmacology, 2014, Volume: 94, Issue:5-6

    Topics: Acetylcholine; Bronchoconstriction; Bronchodilator Agents; Drug Combinations; Glycopyrrolate; Humans; Indans; Pulmonary Disease, Chronic Obstructive; Quinolones

2014
Glycopyrronium bromide for the treatment of chronic obstructive pulmonary disease.
    Expert review of respiratory medicine, 2015, Volume: 9, Issue:1

    Topics: Bronchodilator Agents; Drug Administration Schedule; Glycopyrrolate; Humans; Lung; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Recovery of Function; Severity of Illness Index; Treatment Outcome

2015
Profile of inhaled glycopyrronium bromide as monotherapy and in fixed-dose combination with indacaterol maleate for the treatment of COPD.
    International journal of chronic obstructive pulmonary disease, 2015, Volume: 10

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Animals; Bronchodilator Agents; Drug Combinations; Glycopyrrolate; Humans; Indans; Lung; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Severity of Illness Index; Treatment Outcome

2015
Combination therapy with indacaterol and glycopyrronium bromide in the management of COPD: an update on the evidence for efficacy and safety.
    Therapeutic advances in respiratory disease, 2015, Volume: 9, Issue:2

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Drug Combinations; Glycopyrrolate; Humans; Indans; Lung; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Treatment Outcome

2015
Long-acting muscarinic antagonists for the prevention of exacerbations of chronic obstructive pulmonary disease.
    Therapeutic advances in respiratory disease, 2015, Volume: 9, Issue:3

    Topics: Clinical Trials as Topic; Delayed-Action Preparations; Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Tiotropium Bromide; Tropanes

2015
QVA149 (indacaterol/glycopyrronium) for the treatment of chronic obstructive pulmonary disease.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:7

    Topics: Administration, Inhalation; Bronchodilator Agents; Clinical Trials, Phase III as Topic; Drug Combinations; Dyspnea; Glycopyrrolate; Humans; Indans; Pulmonary Disease, Chronic Obstructive; Quality of Life; Quinolones

2015
Role of combined indacaterol and glycopyrronium bromide (QVA149) for the treatment of COPD in Japan.
    International journal of chronic obstructive pulmonary disease, 2015, Volume: 10

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Drug Administration Schedule; Drug Combinations; Evidence-Based Medicine; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Japan; Lung; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Quinolones; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome

2015
[Are there cardiovascular adverse effects of inhaled anticholinergics?].
    Orvosi hetilap, 2015, Aug-02, Volume: 156, Issue:31

    Topics: Administration, Inhalation; Bronchodilator Agents; Cardiovascular Diseases; Cardiovascular System; Cholinergic Antagonists; Clinical Trials as Topic; Glycopyrrolate; Humans; Incidence; Ipratropium; Pulmonary Disease, Chronic Obstructive; Quinuclidines; Risk Factors; Scopolamine Derivatives; Tiotropium Bromide

2015
Clinical role of dual bronchodilation with an indacaterol-glycopyrronium combination in the management of COPD: its impact on patient-related outcomes and quality of life.
    International journal of chronic obstructive pulmonary disease, 2015, Volume: 10

    Topics: Adrenergic alpha-2 Receptor Agonists; Bronchodilator Agents; Drug Combinations; Glycopyrrolate; Humans; Indans; Lung; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quality of Life; Quinolones; Treatment Outcome

2015
Comparative efficacy of combination bronchodilator therapies in COPD: a network meta-analysis.
    International journal of chronic obstructive pulmonary disease, 2015, Volume: 10

    Topics: Bronchodilator Agents; Drug Combinations; Drug Therapy, Combination; Dyspnea; Forced Expiratory Volume; Formoterol Fumarate; Glycopyrrolate; Humans; Indans; Pulmonary Disease, Chronic Obstructive; Quinolones; Randomized Controlled Trials as Topic; Salmeterol Xinafoate; Tiotropium Bromide; Treatment Outcome

2015
Comparative efficacy of long-acting muscarinic antagonist monotherapies in COPD: a systematic review and network meta-analysis.
    International journal of chronic obstructive pulmonary disease, 2015, Volume: 10

    Topics: Aged; Bayes Theorem; Bronchodilator Agents; Drug Administration Schedule; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Lung; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinuclidines; Randomized Controlled Trials as Topic; Recovery of Function; Spirometry; Surveys and Questionnaires; Time Factors; Tiotropium Bromide; Treatment Outcome; Tropanes

2015
Once-daily glycopyrronium bromide (Seebri Breezhaler(®)) for the treatment of chronic obstructive pulmonary disease (COPD).
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:17

    Topics: Administration, Inhalation; Bronchodilator Agents; Dyspnea; Exercise Tolerance; Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2015
Effect of tiotropium on COPD exacerbations: A systematic review.
    Respiratory medicine, 2016, Volume: 114

    Topics: Administration, Inhalation; Bronchodilator Agents; Cholinergic Antagonists; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Randomized Controlled Trials as Topic; Tiotropium Bromide

2016
[LAMA/LABA fixed dose combination for treatment of COPD].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74, Issue:5

    Topics: Adrenergic beta-2 Receptor Agonists; Benzoxazines; Benzyl Alcohols; Bronchodilator Agents; Chlorobenzenes; Delayed-Action Preparations; Drug Combinations; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Quinuclidines; Respiratory Function Tests; Tiotropium Bromide; Treatment Outcome

2016
NVA237, a long-acting muscarinic antagonist, as an emerging therapy for chronic obstructive pulmonary disease.
    Therapeutic advances in respiratory disease, 2011, Volume: 5, Issue:3

    Topics: Bronchodilator Agents; Delayed-Action Preparations; Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Receptor, Muscarinic M3; Scopolamine Derivatives; Tiotropium Bromide

2011
Once-daily glycopyrronium bromide, a long-acting muscarinic antagonist, for chronic obstructive pulmonary disease: a systematic review of clinical benefit.
    International journal of chronic obstructive pulmonary disease, 2012, Volume: 7

    Topics: Administration, Inhalation; Bronchodilator Agents; Drug Administration Schedule; Exercise Tolerance; Forced Expiratory Volume; Glycopyrrolate; Humans; Lung; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Recovery of Function; Treatment Outcome

2012
Profile of glycopyrronium for once-daily treatment of moderate-to-severe COPD.
    International journal of chronic obstructive pulmonary disease, 2012, Volume: 7

    Topics: Administration, Inhalation; Bronchodilator Agents; Drug Administration Schedule; Exercise Tolerance; Glycopyrrolate; Humans; Lung; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Time Factors; Treatment Outcome

2012

Trials

100 trial(s) available for glycopyrrolate and Airflow Obstruction, Chronic

ArticleYear
Relationship between prior inhaled corticosteroid use and benefits ofbudesonide/glycopyrronium/formoterol fumarate dihydrate on exacerbations, symptoms, health-related quality of life, and lung function in patients with chronic obstructive pulmonary disea
    Respiratory medicine, 2022, Volume: 197

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Bronchodilator Agents; Budesonide; Double-Blind Method; Drug Combinations; Formoterol Fumarate; Glycopyrrolate; Humans; Lung; Metered Dose Inhalers; Pulmonary Disease, Chronic Obstructive; Quality of Life

2022
Bronchodilators in Tobacco-Exposed Persons with Symptoms and Preserved Lung Function.
    The New England journal of medicine, 2022, 09-29, Volume: 387, Issue:13

    Topics: Adrenergic beta-2 Receptor Agonists; Anti-Bacterial Agents; Bronchodilator Agents; Forced Expiratory Volume; Glucocorticoids; Glycopyrrolate; Humans; Lung; Nicotiana; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2022
Effects of long-acting bronchodilators on cardiac autonomic control in COPD.
    Respiratory medicine and research, 2022, Volume: 82

    Topics: Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Glycopyrrolate; Humans; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Tiotropium Bromide

2022
Benefits of Budesonide/Glycopyrronium/Formoterol Fumarate Dihydrate on COPD Exacerbations, Lung Function, Symptoms, and Quality of Life Across Blood Eosinophil Ranges: A Post-Hoc Analysis of Data from ETHOS.
    International journal of chronic obstructive pulmonary disease, 2022, Volume: 17

    Topics: Administration, Inhalation; Bronchodilator Agents; Budesonide; Double-Blind Method; Drug Combinations; Formoterol Fumarate; Glycopyrrolate; Humans; Lung; Pulmonary Disease, Chronic Obstructive; Quality of Life

2022
Pharmacokinetics of budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler formulated using co-suspension delivery technology after single and chronic dosing in patients with COPD.
    Pulmonary pharmacology & therapeutics, 2020, Volume: 60

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Budesonide; Double-Blind Method; Drug Combinations; Drug Delivery Systems; Female; Formoterol Fumarate; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Pulmonary Disease, Chronic Obstructive; Random Allocation

2020
Long-Term Safety and Efficacy of Budesonide/Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Japanese Patients with COPD.
    International journal of chronic obstructive pulmonary disease, 2019, Volume: 14

    Topics: Bronchodilator Agents; Budesonide; Double-Blind Method; Drug Combinations; Drug Monitoring; Drug Tolerance; Female; Formoterol Fumarate; Glycopyrrolate; Humans; Japan; Male; Metered Dose Inhalers; Middle Aged; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests; Severity of Illness Index; Time; Treatment Outcome

2019
Efficacy And Safety Of Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler (GFF MDI) Formulated Using Co-Suspension Delivery Technology In Chinese Patients With COPD.
    International journal of chronic obstructive pulmonary disease, 2020, Volume: 15

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; China; Double-Blind Method; Drug Combinations; Female; Forced Expiratory Volume; Formoterol Fumarate; Glycopyrrolate; Humans; Lung; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Recovery of Function; Severity of Illness Index; Time Factors; Treatment Outcome

2020
Efficacy and Safety of Budesonide/Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler in Chinese Patients with COPD: A Subgroup Analysis of KRONOS.
    Advances in therapy, 2020, Volume: 37, Issue:4

    Topics: Administration, Inhalation; Adult; Aged; Bronchodilator Agents; Budesonide; China; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Forced Expiratory Volume; Formoterol Fumarate; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quality of Life; Respiratory Function Tests

2020
Glycopyrrolate/formoterol fumarate metered dose inhaler for maintenance-naïve patients with chronic obstructive pulmonary disease: a post-hoc analysis of the randomized PINNACLE trials.
    Respiratory research, 2020, Mar-12, Volume: 21, Issue:1

    Topics: Administration, Inhalation; Aged; Bronchodilator Agents; Double-Blind Method; Drug Therapy, Combination; Female; Formoterol Fumarate; Glycopyrrolate; Humans; Internationality; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2020
Impact of baseline symptoms and health status on COPD exacerbations in the FLAME study.
    Respiratory research, 2020, Apr-22, Volume: 21, Issue:1

    Topics: Aged; Bronchodilator Agents; Disease Progression; Double-Blind Method; Drug Combinations; Female; Fluticasone-Salmeterol Drug Combination; Forced Expiratory Volume; Glycopyrrolate; Health Status; Humans; Indans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Surveys and Questionnaires

2020
Triple Inhaled Therapy at Two Glucocorticoid Doses in Moderate-to-Very-Severe COPD.
    The New England journal of medicine, 2020, 07-02, Volume: 383, Issue:1

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Budesonide; Double-Blind Method; Drug Combinations; Female; Forced Expiratory Volume; Formoterol Fumarate; Glucocorticoids; Glycopyrrolate; Humans; Intention to Treat Analysis; Kaplan-Meier Estimate; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2020
Effectiveness and Tolerability of LABA/LAMA Fixed-Dose Combinations Aclidinium/Formoterol, Glycopyrronium/Indacaterol and Umeclidinium/Vilanterol in the Treatment of COPD in Daily Practice - Results of the Non-Interventional DETECT Study.
    International journal of chronic obstructive pulmonary disease, 2020, Volume: 15

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Benzyl Alcohols; Bronchodilator Agents; Chlorobenzenes; Drug Combinations; Formoterol Fumarate; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Quality of Life; Quinolones; Quinuclidines; Treatment Outcome

2020
Early Clinically Important Improvement (ECII) and Exacerbation Outcomes in COPD Patients.
    International journal of chronic obstructive pulmonary disease, 2020, Volume: 15

    Topics: Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Double-Blind Method; Forced Expiratory Volume; Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2020
Long-acting dual bronchodilator therapy (indacaterol/glycopyrronium) versus nebulized short-acting dual bronchodilator (salbutamol/ipratropium) in chronic obstructive pulmonary disease: A double-blind, randomized, placebo-controlled trial.
    Respiratory medicine, 2020, Volume: 171

    Topics: Administration, Inhalation; Aged; Albuterol; Bronchodilator Agents; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glycopyrrolate; Humans; Indans; Ipratropium; Male; Metered Dose Inhalers; Middle Aged; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Quinolones; Treatment Outcome

2020
Efficacy and safety of glycopyrrolate/formoterol fumarate metered dose inhaler delivered using co-suspension delivery technology in Japanese patients with moderate-to-very severe chronic obstructive pulmonary disease.
    Respiratory investigation, 2021, Volume: 59, Issue:1

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Asian People; Delayed-Action Preparations; Double-Blind Method; Drug Delivery Systems; Female; Formoterol Fumarate; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Pulmonary Disease, Chronic Obstructive; Safety; Severity of Illness Index; Suspensions; Treatment Outcome

2021
Ethnic pharmacokinetic comparison of budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler (BGF MDI) between Asian and Western healthy subjects.
    Pulmonary pharmacology & therapeutics, 2020, Volume: 64

    Topics: Administration, Inhalation; Bronchodilator Agents; Budesonide; Double-Blind Method; Drug Combinations; Formoterol Fumarate; Fumarates; Glycopyrrolate; Healthy Volunteers; Humans; Metered Dose Inhalers; Pulmonary Disease, Chronic Obstructive

2020
Efficacy and Safety of Inhaled Glycopyrronium Bromide in COPD: A Randomized, Parallel Group, Dose-Ranging Study (GLIMMER).
    COPD, 2021, Volume: 18, Issue:2

    Topics: Administration, Inhalation; Adult; Bronchodilator Agents; Double-Blind Method; Forced Expiratory Volume; Formoterol Fumarate; Glycopyrrolate; Humans; Pulmonary Disease, Chronic Obstructive; Tiotropium Bromide; Treatment Outcome

2021
Functional respiratory imaging assessment of budesonide/glycopyrrolate/formoterol fumarate and glycopyrrolate/formoterol fumarate metered dose inhalers in patients with COPD: the value of inhaled corticosteroids.
    Respiratory research, 2021, Jul-01, Volume: 22, Issue:1

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Budesonide; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Formoterol Fumarate; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Pulmonary Disease, Chronic Obstructive; Tomography, X-Ray Computed

2021
[Study of the month : FLAME study in chronic obstructive pulmonary disease].
    Revue medicale de Liege, 2016, Volume: 71, Issue:9

    Topics: Administration, Inhalation; Aged; Bronchodilator Agents; Female; Fluticasone; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Salmeterol Xinafoate; Treatment Outcome

2016
Single inhaler extrafine triple therapy versus long-acting muscarinic antagonist therapy for chronic obstructive pulmonary disease (TRINITY): a double-blind, parallel group, randomised controlled trial.
    Lancet (London, England), 2017, May-13, Volume: 389, Issue:10082

    Topics: Administration, Inhalation; Adult; Aged; Beclomethasone; Bronchodilator Agents; Double-Blind Method; Female; Forced Expiratory Volume; Formoterol Fumarate; Glucocorticoids; Glycopyrrolate; Humans; Male; Middle Aged; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Tiotropium Bromide

2017
Long-term safety and efficacy of glycopyrrolate/formoterol metered dose inhaler using novel Co-Suspension™ Delivery Technology in patients with chronic obstructive pulmonary disease.
    Respiratory medicine, 2017, Volume: 126

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; Drug Therapy, Combination; Drug Tolerance; Dyspnea; Female; Forced Expiratory Volume; Formoterol Fumarate; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Smoking; Tiotropium Bromide; Treatment Outcome

2017
Response to Indacaterol/Glycopyrronium (IND/GLY) by Sex in Patients with COPD: A Pooled Analysis from the IGNITE Program.
    COPD, 2017, Volume: 14, Issue:4

    Topics: Aged; Bronchodilator Agents; Drug Combinations; Dyspnea; Female; Fluticasone-Salmeterol Drug Combination; Forced Expiratory Volume; Glucocorticoids; Glycopyrrolate; Health Status; Humans; Indans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Severity of Illness Index; Sex Factors; Tiotropium Bromide; Vital Capacity

2017
Efficacy and safety of direct switch to indacaterol/glycopyrronium in patients with moderate COPD: the CRYSTAL open-label randomised trial.
    Respiratory research, 2017, 07-18, Volume: 18, Issue:1

    Topics: Adrenergic beta-2 Receptor Agonists; Adult; Aged; Bronchodilator Agents; Disease Progression; Drug Combinations; Drug Substitution; Dyspnea; Europe; Female; Forced Expiratory Volume; Glycopyrrolate; Health Status; Humans; Indans; Lung; Male; Middle Aged; Muscarinic Antagonists; Patient Safety; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Quality of Life; Quinolones; Recovery of Function; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome

2017
Baseline Symptom Score Impact on Benefits of Glycopyrrolate/Formoterol Metered Dose Inhaler in COPD.
    Chest, 2017, Volume: 152, Issue:6

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Forced Expiratory Volume; Formoterol Fumarate; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Treatment Outcome

2017
Bronchodilator efficacy of extrafine glycopyrronium bromide: the Glyco 2 study.
    International journal of chronic obstructive pulmonary disease, 2017, Volume: 12

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Albuterol; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; England; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Ipratropium; Lung; Male; Middle Aged; Muscarinic Antagonists; Particle Size; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Time Factors; Tiotropium Bromide; Treatment Outcome

2017
24-h bronchodilation and inspiratory capacity improvements with glycopyrrolate/formoterol fumarate via co-suspension delivery technology in COPD.
    Respiratory research, 2017, 08-18, Volume: 18, Issue:1

    Topics: Aged; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Drug Delivery Systems; Drug Therapy, Combination; Female; Formoterol Fumarate; Glycopyrrolate; Humans; Inspiratory Capacity; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Time Factors

2017
Long-term safety of glycopyrrolate/eFlow
    Respiratory medicine, 2017, Volume: 132

    Topics: Administration, Inhalation; Aged; Bronchodilator Agents; Cough; Female; Forced Expiratory Volume; Gastrointestinal Diseases; Glycopyrrolate; Headache; Humans; Male; Middle Aged; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Respiratory Tract Infections; Severity of Illness Index; Tiotropium Bromide; Vital Capacity

2017
Dual Bronchodilation with Indacaterol Maleate/Glycopyrronium Bromide Compared with Umeclidinium Bromide/Vilanterol in Patients with Moderate-to-Severe COPD: Results from Two Randomized, Controlled, Cross-over Studies.
    Lung, 2017, Volume: 195, Issue:6

    Topics: Aged; Benzyl Alcohols; Bronchodilator Agents; Chlorobenzenes; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Quinuclidines; Severity of Illness Index

2017
Dose selection for glycopyrrolate/eFlow
    Respiratory research, 2017, 12-04, Volume: 18, Issue:1

    Topics: Aged; Bronchodilator Agents; Dose-Response Relationship, Drug; Female; Glycopyrrolate; Humans; Male; Middle Aged; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive

2017
Indacaterol/glycopyrronium is cost-effective compared to salmeterol/fluticasone in COPD: FLAME-based modelling in a Swedish population.
    Respiratory research, 2017, 12-11, Volume: 18, Issue:1

    Topics: Aged; Cost-Benefit Analysis; Double-Blind Method; Drug Combinations; Female; Fluticasone-Salmeterol Drug Combination; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Models, Economic; Population Surveillance; Pulmonary Disease, Chronic Obstructive; Quinolones; Sweden

2017
Effect of adding roflumilast or ciclesonide to glycopyrronium on lung volumes and exercise tolerance in patients with severe COPD: A pilot study.
    Pulmonary pharmacology & therapeutics, 2018, Volume: 49

    Topics: Administration, Inhalation; Administration, Oral; Aged; Albuterol; Aminopyridines; Benzamides; Cyclopropanes; Drug Therapy, Combination; Exercise Tolerance; Female; Glucocorticoids; Glycopyrrolate; Humans; Lung Volume Measurements; Male; Middle Aged; Muscarinic Antagonists; Phosphodiesterase 4 Inhibitors; Pilot Projects; Pregnenediones; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index

2018
Extrafine inhaled triple therapy versus dual bronchodilator therapy in chronic obstructive pulmonary disease (TRIBUTE): a double-blind, parallel group, randomised controlled trial.
    Lancet (London, England), 2018, 03-17, Volume: 391, Issue:10125

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Aged; Beclomethasone; Bronchodilator Agents; Double-Blind Method; Drug Therapy, Combination; Female; Formoterol Fumarate; Glucocorticoids; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones

2018
A phase IIb randomized, chronic-dosing, incomplete block, cross-over study of glycopyrronium, delivered via metered dose inhaler, compared with a placebo and an active control in patients with moderate-to-severe COPD.
    Respiratory research, 2018, 03-05, Volume: 19, Issue:1

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Delivery Systems; Female; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Placebo Effect; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index

2018
Pharmacokinetics of glycopyrronium/formoterol fumarate dihydrate delivered via metered dose inhaler using co-suspension delivery technology in patients with moderate-to-very severe COPD.
    International journal of chronic obstructive pulmonary disease, 2018, Volume: 13

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Australia; Biological Availability; Bronchodilator Agents; Double-Blind Method; Drug Combinations; Female; Formoterol Fumarate; Glycopyrrolate; Humans; Lung; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; New Zealand; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Treatment Outcome; United States

2018
Early Changes in eDiary COPD Symptoms Predict Clinically Relevant Treatment Response at 12 Weeks: Analysis from the CRYSTAL Study.
    COPD, 2018, Volume: 15, Issue:2

    Topics: Aged; Bronchodilator Agents; Drug Combinations; Dyspnea; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Patient Reported Outcome Measures; Prognosis; Pulmonary Disease, Chronic Obstructive; Quinolones; Surveys and Questionnaires; Time Factors; Treatment Outcome

2018
Long-Term Triple Therapy De-escalation to Indacaterol/Glycopyrronium in Patients with Chronic Obstructive Pulmonary Disease (SUNSET): A Randomized, Double-Blind, Triple-Dummy Clinical Trial.
    American journal of respiratory and critical care medicine, 2018, 08-01, Volume: 198, Issue:3

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Aged; Bronchodilator Agents; Double-Blind Method; Female; Fluticasone-Salmeterol Drug Combination; Glucocorticoids; Glycopyrrolate; Humans; Indans; Male; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Tiotropium Bromide; Treatment Outcome

2018
Dose-response of an extrafine dry powder inhaler formulation of glycopyrronium bromide: randomized, double-blind, placebo-controlled, dose-ranging study (GlycoNEXT).
    International journal of chronic obstructive pulmonary disease, 2018, Volume: 13

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Area Under Curve; Bronchodilator Agents; Cross-Over Studies; Czech Republic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Dry Powder Inhalers; Female; Forced Expiratory Volume; Germany; Glycopyrrolate; Humans; Hungary; Lactation; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Romania; Treatment Outcome

2018
Indacaterol/glycopyrronium versus salmeterol/fluticasone in the prevention of clinically important deterioration in COPD: results from the FLAME study.
    Respiratory research, 2018, 06-20, Volume: 19, Issue:1

    Topics: Aged; Bronchodilator Agents; Disease Progression; Double-Blind Method; Drug Combinations; Female; Fluticasone-Salmeterol Drug Combination; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones

2018
Efficacy and safety of four doses of glycopyrrolate/formoterol fumarate delivered via a metered dose inhaler compared with the monocomponents in patients with moderate-to-severe COPD.
    International journal of chronic obstructive pulmonary disease, 2018, Volume: 13

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Area Under Curve; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Forced Expiratory Volume; Formoterol Fumarate; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Nutrition Surveys; Pulmonary Disease, Chronic Obstructive; Reproducibility of Results; Severity of Illness Index

2018
Capturing Exacerbations of Chronic Obstructive Pulmonary Disease with EXACT. A Subanalysis of FLAME.
    American journal of respiratory and critical care medicine, 2019, 01-01, Volume: 199, Issue:1

    Topics: Bronchodilator Agents; Disease Progression; Drug Therapy, Combination; Female; Fluticasone; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Risk Factors; Salmeterol Xinafoate; Surveys and Questionnaires

2019
Efficacy and safety of the direct switch to indacaterol/glycopyrronium from salmeterol/fluticasone in non-frequently exacerbating COPD patients: The FLASH randomized controlled trial.
    Respirology (Carlton, Vic.), 2018, Volume: 23, Issue:12

    Topics: Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; Double-Blind Method; Drug Combinations; Drug Monitoring; Drug Substitution; Female; Fluticasone-Salmeterol Drug Combination; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Respiratory Function Tests; Treatment Outcome

2018
A randomized study using functional respiratory imaging to characterize bronchodilator effects of glycopyrrolate/formoterol fumarate delivered by a metered dose inhaler using co-suspension delivery technology in patients with COPD.
    International journal of chronic obstructive pulmonary disease, 2018, Volume: 13

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Belgium; Bronchodilator Agents; Double-Blind Method; Forced Expiratory Volume; Formoterol Fumarate; Germany; Glycopyrrolate; Humans; London; Male; Metered Dose Inhalers; Middle Aged; Pulmonary Disease, Chronic Obstructive; Respiration; Treatment Outcome

2018
An Open-Label Study Evaluating the Performance of the Dose Indicator in a Metered Dose Inhaler Delivering Glycopyrrolate and Formoterol Fumarate in Patients with Moderate-to-Very Severe Chronic Obstructive Pulmonary Disease.
    Journal of aerosol medicine and pulmonary drug delivery, 2019, Volume: 32, Issue:1

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Drug Combinations; Equipment Design; Female; Formoterol Fumarate; Glycopyrrolate; Humans; Lung; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Treatment Outcome; United States

2019
Satisfaction with the Use of eFlow Closed-System Nebulizer in Patients with Moderate-to-Very Severe Chronic Obstructive Pulmonary Disease: Findings from a Long-Term Safety Study.
    Journal of aerosol medicine and pulmonary drug delivery, 2019, Volume: 32, Issue:1

    Topics: Administration, Inhalation; Aged; Bronchodilator Agents; Equipment Design; Female; Glycopyrrolate; Humans; Lung; Male; Middle Aged; Muscarinic Antagonists; Nebulizers and Vaporizers; Patient Satisfaction; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Time Factors; Tiotropium Bromide; Treatment Outcome

2019
Treatment response to indacaterol/glycopyrronium versus salmeterol/fluticasone in exacerbating COPD patients by gender: a post-hoc analysis in the FLAME study.
    Respiratory research, 2019, Jan-08, Volume: 20, Issue:1

    Topics: Aged; Bronchodilator Agents; Disease Progression; Double-Blind Method; Drug Combinations; Female; Fluticasone-Salmeterol Drug Combination; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Sex Characteristics; Treatment Outcome

2019
Extrafine triple therapy in patients with symptomatic COPD and history of one moderate exacerbation.
    The European respiratory journal, 2019, Volume: 53, Issue:5

    Topics: Administration, Inhalation; Beclomethasone; Bronchodilator Agents; Drug Combinations; Forced Expiratory Volume; Formoterol Fumarate; Glycopyrrolate; Humans; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2019
A Randomized, Double-Blind, Double-Dummy Study of Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Relative to Umeclidinium/Vilanterol Dry Powder Inhaler in COPD.
    Advances in therapy, 2019, Volume: 36, Issue:9

    Topics: Administration, Inhalation; Aged; Benzyl Alcohols; Bronchodilator Agents; Chlorobenzenes; Double-Blind Method; Dry Powder Inhalers; Female; Forced Expiratory Volume; Formoterol Fumarate; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests; Treatment Outcome

2019
Bone and ocular safety of budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a 52-week randomized study.
    Respiratory research, 2019, Jul-29, Volume: 20, Issue:1

    Topics: Aged; Anti-Asthmatic Agents; Bone Density; Bronchodilator Agents; Budesonide, Formoterol Fumarate Drug Combination; Cataract; Double-Blind Method; Female; Glycopyrrolate; Humans; Intraocular Pressure; Lens, Crystalline; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2019
Safety and efficacy of dual bronchodilation with QVA149 in COPD patients: the ENLIGHTEN study.
    Respiratory medicine, 2013, Volume: 107, Issue:10

    Topics: Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; Double-Blind Method; Drug Combinations; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Male; Medication Adherence; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Spirometry; Treatment Outcome; Vital Capacity

2013
Efficacy and safety of QVA149 compared to the concurrent administration of its monocomponents indacaterol and glycopyrronium: the BEACON study.
    International journal of chronic obstructive pulmonary disease, 2013, Volume: 8

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Lung; Male; Middle Aged; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Quinolones; Severity of Illness Index; Time Factors; Treatment Outcome

2013
Dual bronchodilation with QVA149 reduces patient-reported dyspnoea in COPD: the BLAZE study.
    The European respiratory journal, 2014, Volume: 43, Issue:6

    Topics: Adult; Aged; Area Under Curve; Bronchodilator Agents; Cross-Over Studies; Drug Combinations; Dyspnea; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Powders; Pulmonary Disease, Chronic Obstructive; Quinolones; Scopolamine Derivatives; Spirometry; Tiotropium Bromide; Treatment Outcome

2014
Combined long-acting bronchodilator single therapy for COPD.
    Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:1

    Topics: Bronchodilator Agents; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Male; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Quinolones

2014
Efficacy and safety of once-daily QVA149 compared with twice-daily salmeterol-fluticasone in patients with chronic obstructive pulmonary disease (ILLUMINATE): a randomised, double-blind, parallel group study.
    The Lancet. Respiratory medicine, 2013, Volume: 1, Issue:1

    Topics: Administration, Inhalation; Albuterol; Androstadienes; Bronchodilator Agents; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Fluticasone-Salmeterol Drug Combination; Glucocorticoids; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Sympathomimetics; Treatment Outcome

2013
Analysis of chronic obstructive pulmonary disease exacerbations with the dual bronchodilator QVA149 compared with glycopyrronium and tiotropium (SPARK): a randomised, double-blind, parallel-group study.
    The Lancet. Respiratory medicine, 2013, Volume: 1, Issue:3

    Topics: Administration, Inhalation; Aged; Bronchodilator Agents; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Drug Monitoring; Female; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Respiratory Function Tests; Respiratory System; Scopolamine Derivatives; Severity of Illness Index; Tiotropium Bromide; Treatment Outcome

2013
A blinded evaluation of the efficacy and safety of glycopyrronium, a once-daily long-acting muscarinic antagonist, versus tiotropium, in patients with COPD: the GLOW5 study.
    BMC pulmonary medicine, 2014, Jan-17, Volume: 14

    Topics: Double-Blind Method; Drug Administration Schedule; Female; Glycopyrrolate; Humans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Scopolamine Derivatives; Tiotropium Bromide

2014
Effect of QVA149 on lung volumes and exercise tolerance in COPD patients: the BRIGHT study.
    Respiratory medicine, 2014, Volume: 108, Issue:4

    Topics: Adult; Aged; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Exercise Tolerance; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Lung Volume Measurements; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Scopolamine Derivatives; Spirometry; Tiotropium Bromide; Treatment Outcome; Vital Capacity

2014
Efficacy and safety of coadministration of once-daily indacaterol and glycopyrronium versus indacaterol alone in COPD patients: the GLOW6 study.
    International journal of chronic obstructive pulmonary disease, 2014, Volume: 9

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Aged; Area Under Curve; Bronchodilator Agents; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Europe; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Inspiratory Capacity; Lung; Male; Middle Aged; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Quinolones; Severity of Illness Index; Time Factors; Treatment Outcome; Vital Capacity

2014
Randomized study of the safety, pharmacokinetics, and bronchodilatory efficacy of a proprietary glycopyrronium metered-dose inhaler in study patients with chronic obstructive pulmonary disease.
    BMC pulmonary medicine, 2014, Jul-16, Volume: 14

    Topics: Adult; Aged; Area Under Curve; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Scopolamine Derivatives; Tiotropium Bromide; Xerostomia

2014
Pooled safety analysis of the fixed-dose combination of indacaterol and glycopyrronium (QVA149), its monocomponents, and tiotropium versus placebo in COPD patients.
    Respiratory medicine, 2014, Volume: 108, Issue:10

    Topics: Aged; Bronchodilator Agents; Drug Combinations; Drug Therapy, Combination; Female; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Risk Factors; Scopolamine Derivatives; Tiotropium Bromide; Treatment Outcome

2014
Translational Study Searching for Synergy between Glycopyrronium and Indacaterol.
    COPD, 2015, Volume: 12, Issue:2

    Topics: Administration, Inhalation; Aged; Aged, 80 and over; Bronchi; Bronchodilator Agents; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Single-Blind Method; Translational Research, Biomedical; Treatment Outcome

2015
Efficacy and safety of nebulized glycopyrrolate for administration using a high efficiency nebulizer in patients with chronic obstructive pulmonary disease.
    British journal of clinical pharmacology, 2015, Volume: 79, Issue:3

    Topics: Administration, Inhalation; Adult; Aged; Blood Pressure; Bronchodilator Agents; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Equipment Design; Female; Glycopyrrolate; Heart Rate; Humans; Male; Middle Aged; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests; Severity of Illness Index

2015
Cost-effectiveness of the LABA/LAMA dual bronchodilator indacaterol/glycopyrronium in a Swedish healthcare setting.
    Respiratory medicine, 2014, Volume: 108, Issue:12

    Topics: Aged; Albuterol; Androstadienes; Bronchodilator Agents; Cost-Benefit Analysis; Double-Blind Method; Drug Combinations; Drug Costs; Drug Therapy, Combination; Female; Fluticasone; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Monte Carlo Method; Pulmonary Disease, Chronic Obstructive; Quinolones; Salmeterol Xinafoate; Sweden

2014
The Prospective Non-Interventional DACCORD Study in the National COPD Registry in Germany: design and methods.
    BMC pulmonary medicine, 2015, Jan-12, Volume: 15

    Topics: Adrenergic beta-2 Receptor Agonists; Adult; Bronchodilator Agents; Female; Follow-Up Studies; Germany; Glycopyrrolate; Humans; Male; Outpatients; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Registries; Treatment Outcome

2015
Efficacy and safety of once-daily glycopyrronium in predominantly Chinese patients with moderate-to-severe chronic obstructive pulmonary disease: the GLOW7 study.
    International journal of chronic obstructive pulmonary disease, 2015, Volume: 10

    Topics: Adult; Aged; Asian People; Bronchodilator Agents; China; Double-Blind Method; Drug Administration Schedule; Dyspnea; Female; Forced Expiratory Volume; Glycopyrrolate; Health Status; Humans; India; Lung; Male; Middle Aged; Muscarinic Antagonists; Philippines; Pulmonary Disease, Chronic Obstructive; Recovery of Function; Republic of Korea; Severity of Illness Index; Spirometry; Surveys and Questionnaires; Time Factors; Treatment Outcome; Vital Capacity

2015
Glycopyrronium + indacaterol. A fixed-dose combination with no advantages in COPD.
    Prescrire international, 2014, Volume: 23, Issue:155

    Topics: Adrenergic beta-2 Receptor Agonists; Double-Blind Method; Drug Therapy, Combination; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones

2014
Efficacy and safety of once-daily QVA149 compared with the free combination of once-daily tiotropium plus twice-daily formoterol in patients with moderate-to-severe COPD (QUANTIFY): a randomised, non-inferiority study.
    Thorax, 2015, Volume: 70, Issue:4

    Topics: Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Ethanolamines; Female; Forced Expiratory Volume; Formoterol Fumarate; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quality of Life; Quinolones; Scopolamine Derivatives; Tiotropium Bromide; Treatment Outcome; Vital Capacity

2015
Glycopyrronium once-daily significantly improves lung function and health status when combined with salmeterol/fluticasone in patients with COPD: the GLISTEN study, a randomised controlled trial.
    Thorax, 2015, Volume: 70, Issue:6

    Topics: Administration, Inhalation; Aged; Albuterol; Androstadienes; Australia; Bronchodilator Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluticasone; Forced Expiratory Volume; Glycopyrrolate; Health Status; Humans; Male; Middle Aged; New Zealand; Pulmonary Disease, Chronic Obstructive; Risk Factors; Salmeterol Xinafoate; Scopolamine Derivatives; Severity of Illness Index; Surveys and Questionnaires; Tiotropium Bromide; Treatment Outcome

2015
Pharmacological assessment of the onset of action of aclidinium and glycopyrronium versus tiotropium in COPD patients and human isolated bronchi.
    European journal of pharmacology, 2015, Aug-15, Volume: 761

    Topics: Administration, Inhalation; Bronchi; Bronchoconstriction; Bronchodilator Agents; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; In Vitro Techniques; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Time Factors; Tiotropium Bromide; Treatment Outcome; Tropanes

2015
LANTERN: a randomized study of QVA149 versus salmeterol/fluticasone combination in patients with COPD.
    International journal of chronic obstructive pulmonary disease, 2015, Volume: 10

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Bronchodilator Agents; Double-Blind Method; Drug Combinations; Female; Fluticasone-Salmeterol Drug Combination; Forced Expiratory Volume; Glucocorticoids; Glycopyrrolate; Humans; Indans; Lung; Male; Middle Aged; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Quinolones; Recovery of Function; Severity of Illness Index; Spirometry; Surveys and Questionnaires; Time Factors; Treatment Outcome

2015
FLIGHT1 and FLIGHT2: Efficacy and Safety of QVA149 (Indacaterol/Glycopyrrolate) versus Its Monocomponents and Placebo in Patients with Chronic Obstructive Pulmonary Disease.
    American journal of respiratory and critical care medicine, 2015, Nov-01, Volume: 192, Issue:9

    Topics: Bronchodilator Agents; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome

2015
[LAMA/LABA or LABA/ICS?].
    MMW Fortschritte der Medizin, 2015, Aug-20, Volume: 157, Issue:14

    Topics: Administration, Inhalation; Drug Therapy, Combination; Fluticasone; Forced Expiratory Volume; Glycopyrrolate; Indans; Lung Volume Measurements; Pulmonary Disease, Chronic Obstructive; Quinolones; Salmeterol Xinafoate

2015
Faster reduction in hyperinflation and improvement in lung ventilation inhomogeneity promoted by aclidinium compared to glycopyrronium in severe stable COPD patients. A randomized crossover study.
    Pulmonary pharmacology & therapeutics, 2015, Volume: 35

    Topics: Aged; Aged, 80 and over; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Dyspnea; Endpoint Determination; Female; Glycopyrrolate; Humans; Lung; Male; Middle Aged; Plethysmography; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Residual Volume; Respiratory Function Tests; Tropanes

2015
Bronchodilator effects, pharmacokinetics and safety of PSX1002-GB, a novel glycopyrronium bromide formulation, in COPD patients; a randomised crossover study.
    Pulmonary pharmacology & therapeutics, 2016, Volume: 37

    Topics: Aged; Bronchodilator Agents; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Pulmonary Disease, Chronic Obstructive; Time Factors; Treatment Outcome

2016
[LAMA/LABA supports physical activity in COPD patients].
    MMW Fortschritte der Medizin, 2016, Feb-04, Volume: 158, Issue:2

    Topics: Drug Combinations; Glycopyrrolate; Humans; Indans; Motor Activity; Pulmonary Disease, Chronic Obstructive; Quinolones

2016
The bronchodilator effects of extrafine glycopyrronium added to combination treatment with beclometasone dipropionate plus formoterol in COPD: A randomised crossover study (the TRIDENT study).
    Respiratory medicine, 2016, Volume: 114

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Aged; Beclomethasone; Bronchodilator Agents; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Forced Expiratory Volume; Formoterol Fumarate; Glucocorticoids; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Predictive Value of Tests; Pulmonary Disease, Chronic Obstructive; Treatment Outcome; Vital Capacity

2016
Indacaterol-Glycopyrronium versus Salmeterol-Fluticasone for COPD.
    The New England journal of medicine, 2016, 06-09, Volume: 374, Issue:23

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Aged; Double-Blind Method; Drug Combinations; Female; Fluticasone-Salmeterol Drug Combination; Glucocorticoids; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones

2016
Long-term safety of glycopyrrolate: A randomized study in patients with moderate-to-severe COPD (GEM3).
    Respiratory medicine, 2016, Volume: 115

    Topics: Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; Double-Blind Method; Electrocardiography; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Severity of Illness Index; Treatment Outcome; United States; Vital Capacity; Vital Signs

2016
[Dual bronchodilators becomes the first choice combination].
    MMW Fortschritte der Medizin, 2016, Jun-09, Volume: 158, Issue:11

    Topics: Adrenergic beta-2 Receptor Agonists; Double-Blind Method; Drug Combinations; Fluticasone; Glycopyrrolate; Guideline Adherence; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Salmeterol Xinafoate

2016
Effects of indacaterol/glycopyrronium (QVA149) on lung hyperinflation and physical activity in patients with moderate to severe COPD: a randomised, placebo-controlled, crossover study (The MOVE Study).
    BMC pulmonary medicine, 2016, Jun-14, Volume: 16, Issue:1

    Topics: Aged; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Drug Combinations; Exercise; Female; Forced Expiratory Volume; Germany; Glycopyrrolate; Humans; Indans; Inspiratory Capacity; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones

2016
Efficacy and safety of twice-daily glycopyrrolate in patients with stable, symptomatic COPD with moderate-to-severe airflow limitation: the GEM1 study.
    International journal of chronic obstructive pulmonary disease, 2016, Volume: 11

    Topics: Administration, Inhalation; Aged; Bronchodilator Agents; Double-Blind Method; Drug Administration Schedule; Dyspnea; Female; Forced Expiratory Volume; Glycopyrrolate; Health Status; Humans; Lung; Male; Middle Aged; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Spirometry; Surveys and Questionnaires; Time Factors; Treatment Outcome; United States

2016
Efficacy of Double Bronchodilation (LABA+LAMA) in Patients with Chronic Obstructive Pulmonary Disease (COPD) and Lung Cancer.
    Archivos de bronconeumologia, 2016, Volume: 52, Issue:12

    Topics: Adenocarcinoma; Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; Carcinoma, Squamous Cell; Delayed-Action Preparations; Female; Glycopyrrolate; Humans; Indans; Lung Neoplasms; Male; Middle Aged; Muscarinic Antagonists; Pilot Projects; Pneumonectomy; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Quinolones

2016
Early bronchodilator action of glycopyrronium versus tiotropium in moderate-to-severe COPD patients: a cross-over blinded randomized study (Symptoms and Pulmonary function in the moRnING).
    International journal of chronic obstructive pulmonary disease, 2016, Volume: 11

    Topics: Administration, Inhalation; Aged; Bronchodilator Agents; Circadian Rhythm; Cross-Over Studies; Drug Administration Schedule; Europe; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Lung; Male; Middle Aged; Muscarinic Antagonists; Patient Reported Outcome Measures; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Quality of Life; Recovery of Function; Severity of Illness Index; Time Factors; Tiotropium Bromide; Treatment Outcome; Vital Capacity

2016
Dose-response to inhaled glycopyrrolate delivered with a novel Co-Suspension™ Delivery Technology metered dose inhaler (MDI) in patients with moderate-to-severe COPD.
    Respiratory research, 2016, 09-02, Volume: 17, Issue:1

    Topics: Administration, Inhalation; Aged; Bronchodilator Agents; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Equipment Design; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Lung; Male; Maximum Tolerated Dose; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Time Factors; Treatment Outcome; United States; Vital Capacity

2016
Computed tomography (CT)-assessed bronchodilation induced by inhaled indacaterol and glycopyrronium/indacaterol in COPD.
    Respiratory medicine, 2016, Volume: 119

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aged; Aged, 80 and over; Bronchi; Bronchodilator Agents; Drug Therapy, Combination; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Japan; Lung; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Respiratory Function Tests; Tomography, X-Ray Computed

2016
A multicenter, randomized, double-blind dose-ranging study of glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler compared to the monocomponents and open-label tiotropium dry powder inhaler in patients with moderate-to-severe CO
    Respiratory medicine, 2016, Volume: 120

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Cholinergic Antagonists; Cross-Over Studies; Double-Blind Method; Drug Combinations; Dry Powder Inhalers; Female; Forced Expiratory Volume; Formoterol Fumarate; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Tiotropium Bromide; Treatment Outcome

2016
Efficacy and Safety of Glycopyrrolate/Formoterol Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Patients With COPD.
    Chest, 2017, Volume: 151, Issue:2

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Budesonide; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Fluticasone; Forced Expiratory Volume; Formoterol Fumarate; Glucocorticoids; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Prednisone; Pulmonary Disease, Chronic Obstructive; Suspensions; Vital Capacity

2017
Fast onset of action of glycopyrronium compared with tiotropium in patients with moderate to severe COPD - A randomised, multicentre, crossover trial.
    Pulmonary pharmacology & therapeutics, 2017, Volume: 42

    Topics: Administration, Inhalation; Aged; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Germany; Glycopyrrolate; Humans; Inspiratory Capacity; Male; Middle Aged; Plethysmography, Whole Body; Pulmonary Disease, Chronic Obstructive; Residual Volume; Severity of Illness Index; Spirometry; Time Factors; Tiotropium Bromide

2017
A randomized, seven-day study to assess the efficacy and safety of a glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler using novel Co-Suspension™ Delivery Technology in patients with moderate-to-very severe chronic obstructive
    Respiratory research, 2017, 01-06, Volume: 18, Issue:1

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Australia; Double-Blind Method; Drug Combinations; Equipment Design; Equipment Failure Analysis; Female; Formoterol Fumarate; Glycopyrrolate; Humans; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; New Zealand; Placebo Effect; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Treatment Outcome; United States

2017
Indacaterol and glycopyrronium versus indacaterol on body plethysmography measurements in COPD-a randomised controlled study.
    Respiratory research, 2017, 01-11, Volume: 18, Issue:1

    Topics: Adrenergic beta-2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Cross-Over Studies; Diagnosis, Computer-Assisted; Double-Blind Method; Drug Combinations; Female; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Muscarinic Antagonists; Placebo Effect; Plethysmography, Whole Body; Pulmonary Disease, Chronic Obstructive; Quinolones; Reproducibility of Results; Respiratory Function Tests; Sensitivity and Specificity; Spirometry; Switzerland; Treatment Outcome

2017
Efficacy and safety of indacaterol/glycopyrronium fixed-dose combination in mild-to-moderate COPD patients symptomatic on tiotropium in Korea: study protocol for a randomized controlled trial.
    Trials, 2017, 02-22, Volume: 18, Issue:1

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Cholinergic Antagonists; Clinical Protocols; Drug Administration Schedule; Drug Combinations; Drug Substitution; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Lung; Male; Pulmonary Disease, Chronic Obstructive; Quinolones; Recovery of Function; Republic of Korea; Research Design; Severity of Illness Index; Spirometry; Time Factors; Tiotropium Bromide; Treatment Outcome; Vital Capacity

2017
Safety and tolerability of NVA237, a once-daily long-acting muscarinic antagonist, in COPD patients.
    Pulmonary pharmacology & therapeutics, 2010, Volume: 23, Issue:5

    Topics: Administration, Inhalation; Aged; Aged, 80 and over; Bronchodilator Agents; Double-Blind Method; Drug Administration Schedule; Female; Glycopyrrolate; Humans; Male; Middle Aged; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive

2010
Sustained 24-h efficacy of NVA237, a once-daily long-acting muscarinic antagonist, in COPD patients.
    Respiratory medicine, 2010, Volume: 104, Issue:10

    Topics: Aged; Aged, 80 and over; Bronchodilator Agents; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Scopolamine Derivatives; Time Factors; Tiotropium Bromide; Treatment Outcome

2010
QVA149 demonstrates superior bronchodilation compared with indacaterol or placebo in patients with chronic obstructive pulmonary disease.
    Thorax, 2010, Volume: 65, Issue:12

    Topics: Aged; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Combinations; Epidemiologic Methods; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Treatment Outcome; Vital Capacity

2010
Bronchodilatory effects of NVA237, a once daily long-acting muscarinic antagonist, in COPD patients.
    Respiratory medicine, 2011, Volume: 105, Issue:3

    Topics: Administration, Inhalation; Aged; Aged, 80 and over; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Spirometry; Treatment Outcome

2011
Cardiovascular safety of QVA149, a combination of Indacaterol and NVA237, in COPD patients.
    COPD, 2010, Volume: 7, Issue:6

    Topics: Administration, Inhalation; Aged; Atrial Fibrillation; Blood Pressure; Bronchodilator Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Electrocardiography, Ambulatory; Female; Glycopyrrolate; Heart Rate; Humans; Hyperkalemia; Indans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Tachycardia, Ventricular

2010
Efficacy and safety of once-daily NVA237 in patients with moderate-to-severe COPD: the GLOW1 trial.
    Respiratory research, 2011, Dec-07, Volume: 12

    Topics: Female; Glycopyrrolate; Humans; Male; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quality of Life; Single-Blind Method; Treatment Outcome

2011
Pharmacokinetics of multiple inhaled NVA237 doses in patients with chronic obstructive pulmonary disease (COPD).
    International journal of clinical pharmacology and therapeutics, 2012, Volume: 50, Issue:2

    Topics: Administration, Inhalation; Aged; Area Under Curve; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glycopyrrolate; Half-Life; Humans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Stereoisomerism

2012
Once-daily NVA237 improves exercise tolerance from the first dose in patients with COPD: the GLOW3 trial.
    International journal of chronic obstructive pulmonary disease, 2012, Volume: 7

    Topics: Adult; Aged; Aged, 80 and over; Cross-Over Studies; Drug Administration Schedule; Exercise Test; Exercise Tolerance; Female; Forced Expiratory Volume; Functional Residual Capacity; Glycopyrrolate; Humans; Lung; Lung Volume Measurements; Male; Middle Aged; Muscarinic Antagonists; Plethysmography; Pulmonary Disease, Chronic Obstructive; Recovery of Function; Residual Volume; Severity of Illness Index; Spirometry; Time Factors; Treatment Outcome

2012
Efficacy and safety of NVA237 versus placebo and tiotropium in patients with COPD: the GLOW2 study.
    The European respiratory journal, 2012, Volume: 40, Issue:5

    Topics: Bronchodilator Agents; Double-Blind Method; Female; Glycopyrrolate; Humans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Scopolamine Derivatives; Tiotropium Bromide

2012
A novel model-based approach for dose determination of glycopyrronium bromide in COPD.
    BMC pulmonary medicine, 2012, Dec-08, Volume: 12

    Topics: Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Male; Middle Aged; Models, Biological; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Time Factors; Treatment Outcome

2012

Other Studies

93 other study(ies) available for glycopyrrolate and Airflow Obstruction, Chronic

ArticleYear
Real-world Safety and Efficacy of Indacaterol/Glycopyrronium in Japanese Patients with Chronic Obstructive Pulmonary Disease: A 52-week Post-marketing Surveillance.
    Internal medicine (Tokyo, Japan), 2022, Mar-15, Volume: 61, Issue:6

    Topics: Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; Drug Combinations; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Japan; Muscarinic Antagonists; Product Surveillance, Postmarketing; Pulmonary Disease, Chronic Obstructive; Quinolones; Treatment Outcome

2022
Which LABA/LAMA should be chosen in COPD patients in real life?
    Pulmonary pharmacology & therapeutics, 2021, Volume: 71

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Drug Combinations; Female; Glycopyrrolate; Humans; Male; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Retrospective Studies; Treatment Outcome

2021
[Fixed combination of mometasone, indacaterol, glycopyrronium for the treatment of severe asthma : Enerzair® Breezhaler®].
    Revue medicale de Liege, 2021, Volume: 76, Issue:10

    Topics: Administration, Inhalation; Asthma; Glycopyrrolate; Humans; Indans; Mometasone Furoate; Pulmonary Disease, Chronic Obstructive; Quinolones

2021
[Fixed combination of budesonide, formoterol, glycopyrronium for the treatment of severe COPD : Trixeo Aerosphere®].
    Revue medicale de Liege, 2022, Volume: 77, Issue:4

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic Agonists; Bronchodilator Agents; Budesonide; Drug Combinations; Formoterol Fumarate; Glycopyrrolate; Humans; Metered Dose Inhalers; Pulmonary Disease, Chronic Obstructive; Quality of Life

2022
Comparing Clinical Outcomes of Tiotropium/Olodaterol, Umeclidinium/Vilanterol, and Indacaterol/Glycopyrronium Fixed-Dose Combination Therapy in Patients with Chronic Obstructive Pulmonary Disease in Taiwan: A Multicenter Cohort Study.
    International journal of chronic obstructive pulmonary disease, 2022, Volume: 17

    Topics: Adrenergic beta-2 Receptor Agonists; Benzoxazines; Benzyl Alcohols; Bronchodilator Agents; Chlorobenzenes; Drug Combinations; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Quinuclidines; Retrospective Studies; Taiwan; Tiotropium Bromide; Treatment Outcome

2022
Effects of long-acting muscarinic antagonists on promoting ciliary function in airway epithelium.
    BMC pulmonary medicine, 2022, May-08, Volume: 22, Issue:1

    Topics: Animals; Asthma; Epithelium; Glycopyrrolate; Humans; Mice; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Stroke; Tiotropium Bromide; Trachea

2022
Budesonide/glycopyrronium/formoterol fumarate triple therapy prevents pulmonary hypertension in a COPD mouse model via NFκB inactivation.
    Respiratory research, 2022, Jun-27, Volume: 23, Issue:1

    Topics: Animals; Bronchodilator Agents; Budesonide; Budesonide, Formoterol Fumarate Drug Combination; Emphysema; Endothelial Cells; Formoterol Fumarate; Fumarates; Glycopyrrolate; Hypertension, Pulmonary; Mice; NF-kappa B; Pancreatic Elastase; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema

2022
Cost-Effectiveness Analysis of Triple Therapy with Budesonide/ Glycopyrronium/ Formoterol Fumarate versus Dual Therapy in Patients with Chronic Obstructive Pulmonary Disease in Spain.
    International journal of chronic obstructive pulmonary disease, 2022, Volume: 17

    Topics: Bronchodilator Agents; Budesonide; Budesonide, Formoterol Fumarate Drug Combination; Cost-Benefit Analysis; Formoterol Fumarate; Fumarates; Glycopyrrolate; Humans; Pulmonary Disease, Chronic Obstructive; Spain

2022
Cost-Effectiveness of Triple Therapy with Budesonide/Glycopyrronium/Formoterol Fumarate Dihydrate versus Dual Therapies in Moderate-to-Very Severe Chronic Obstructive Pulmonary Disease: United Kingdom Analysis Using the ETHOS Study.
    International journal of chronic obstructive pulmonary disease, 2022, Volume: 17

    Topics: Budesonide; Cost-Benefit Analysis; Formoterol Fumarate; Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quality of Life; State Medicine

2022
Ultrasound assessment of diaphragmatic dynamics in patients with chronic obstructive pulmonary disease after treatment with indacaterol/glycopyrronium.
    Revista clinica espanola, 2023, Volume: 223, Issue:4

    Topics: Aged; Bronchodilator Agents; Diaphragm; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Lung; Male; Middle Aged; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2023
Chronic Obstructive Pulmonary Disease Exacerbations and Pneumonia Hospitalizations Among New Users of Combination Maintenance Inhalers.
    JAMA internal medicine, 2023, 07-01, Volume: 183, Issue:7

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; Cohort Studies; Drug Therapy, Combination; Female; Fluticasone; Formoterol Fumarate; Glycopyrrolate; Humans; Male; Muscarinic Antagonists; Nebulizers and Vaporizers; Pneumonia; Pulmonary Disease, Chronic Obstructive

2023
Real-world comparative effectiveness of three single-inhaler dual bronchodilators for the treatment of COPD.
    The European respiratory journal, 2023, Volume: 62, Issue:2

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Drug Combinations; Glycopyrrolate; Humans; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2023
Comparative Effectiveness of Umeclidinium/Vilanterol versus Indacaterol/Glycopyrronium on Moderate-to-Severe Exacerbations in Patients with Chronic Obstructive Pulmonary Disease in Clinical Practice in England.
    International journal of chronic obstructive pulmonary disease, 2023, Volume: 18

    Topics: England; Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Retrospective Studies

2023
The effect of inhaled extrafine beclometasone dipropionate/formoterol fumarate/glycopyrronium bromide on distal and central airway indices, assessed using Functional Respiratory Imaging in COPD (DARWiIN).
    Respiratory research, 2023, Oct-06, Volume: 24, Issue:1

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Beclomethasone; Bronchodilator Agents; Drug Combinations; Fluticasone-Salmeterol Drug Combination; Formoterol Fumarate; Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2023
Exacerbations and Real-World Outcomes After Single-Inhaler Triple Therapy of Budesonide/Glycopyrrolate/Formoterol Fumarate, Among Patients with COPD: Results from the EROS (US) Study.
    International journal of chronic obstructive pulmonary disease, 2023, Volume: 18

    Topics: Administration, Inhalation; Bronchodilator Agents; Budesonide; Double-Blind Method; Drug Combinations; Formoterol Fumarate; Glycopyrrolate; Humans; Metered Dose Inhalers; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Retrospective Studies

2023
One bronchodilator or two? Translating clinical trials into clinical practice.
    Respirology (Carlton, Vic.), 2020, Volume: 25, Issue:4

    Topics: Bronchodilator Agents; Glycopyrrolate; Humans; Indans; Pulmonary Disease, Chronic Obstructive; Quinolones; Tiotropium Bromide

2020
Beclomethasone dipropionate, formoterol fumarate and glycopyrronium bromide: Synergy of triple combination therapy on human airway smooth muscle ex vivo.
    British journal of pharmacology, 2020, Volume: 177, Issue:5

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Beclomethasone; Bronchodilator Agents; Drug Combinations; Drug Therapy, Combination; Formoterol Fumarate; Glycopyrrolate; Humans; Muscarinic Antagonists; Muscle, Smooth; Pulmonary Disease, Chronic Obstructive

2020
Dual use of bronchodilators versus monotherapy, and its impact on pulmonary rehabilitation in COPD patients.
    Pulmonary pharmacology & therapeutics, 2020, Volume: 61

    Topics: Adrenergic beta-2 Receptor Agonists; Aged; Aged, 80 and over; Bronchodilator Agents; Drug Therapy, Combination; Female; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Muscarinic Antagonists; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Quinolones; Tiotropium Bromide

2020
Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Improves Lung Function versus Monotherapies in GOLD Category A Patients with COPD: Pooled Data from the Phase III PINNACLE Studies.
    International journal of chronic obstructive pulmonary disease, 2020, Volume: 15

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; Clinical Trials, Phase III as Topic; Drug Combinations; Female; Forced Expiratory Volume; Formoterol Fumarate; Glycopyrrolate; Humans; Lung; Male; Metered Dose Inhalers; Middle Aged; Multicenter Studies as Topic; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Recovery of Function; Severity of Illness Index; Time Factors; Treatment Outcome

2020
COPD clinical control as a predictor of future exacerbations: concept validation in the SPARK study population.
    Thorax, 2020, Volume: 75, Issue:4

    Topics: Aged; Bronchodilator Agents; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Quinolones; Reproducibility of Results; Respiratory Function Tests; Risk Assessment; Severity of Illness Index; Tiotropium Bromide; Treatment Outcome

2020
[Assessment of patient-reported outcomes by questionnaires in patients with Moderate and severe chronic obstructive pulmonary disease treated with glycopyrroniUm in the reaL lifE setTing in Hungary (AMULET)].
    Orvosi hetilap, 2020, Volume: 161, Issue:8

    Topics: Glycopyrrolate; Humans; Hungary; Patient Reported Outcome Measures; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index

2020
The Effect of Baseline Rescue Medication Use on Efficacy and Safety of Nebulized Glycopyrrolate Treatment in Patients with COPD from the GOLDEN 3 and 4 Studies.
    International journal of chronic obstructive pulmonary disease, 2020, Volume: 15

    Topics: Administration, Inhalation; Bronchodilator Agents; Double-Blind Method; Forced Expiratory Volume; Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2020
Modelling the Cost-Effectiveness of Indacaterol/Glycopyrronium versus Salmeterol/Fluticasone Using a Novel Markov Exacerbation-Based Approach.
    International journal of chronic obstructive pulmonary disease, 2020, Volume: 15

    Topics: Bronchodilator Agents; Cost-Benefit Analysis; Drug Combinations; Fluticasone-Salmeterol Drug Combination; Glycopyrrolate; Humans; Indans; Markov Chains; Pulmonary Disease, Chronic Obstructive; Quinolones; Sweden; Treatment Outcome

2020
Effect of Gender on Lung Function and Patient-Reported Outcomes in Patients with COPD Receiving Nebulized Glycopyrrolate.
    International journal of chronic obstructive pulmonary disease, 2020, Volume: 15

    Topics: Administration, Inhalation; Bronchodilator Agents; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Lung; Male; Muscarinic Antagonists; Nebulizers and Vaporizers; Patient Reported Outcome Measures; Pulmonary Disease, Chronic Obstructive; Quality of Life; Treatment Outcome

2020
Observational Real-World Study to Assess Clinical Characteristics and Device Satisfaction in Patients with COPD Treated with Glycopyrrolate/eFlow
    International journal of chronic obstructive pulmonary disease, 2020, Volume: 15

    Topics: Administration, Inhalation; Aged; Cross-Sectional Studies; Female; Glycopyrrolate; Humans; Middle Aged; Muscarinic Antagonists; Patient Satisfaction; Personal Satisfaction; Pulmonary Disease, Chronic Obstructive

2020
Sialorrhoea treated with inhaled glycopyrronium.
    BMJ supportive & palliative care, 2021, Volume: 11, Issue:4

    Topics: Adult; Aged; Glycopyrrolate; Humans; Male; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Sialorrhea

2021
Reigniting the TORCH: Chronic Obstructive Pulmonary Disease Mortality and Inhaled Corticosteroids Revisited.
    American journal of respiratory and critical care medicine, 2021, 03-01, Volume: 203, Issue:5

    Topics: Adrenal Cortex Hormones; Budesonide; Double-Blind Method; Formoterol Fumarate; Glycopyrrolate; Humans; Pulmonary Disease, Chronic Obstructive

2021
Reply to López-Campos
    American journal of respiratory and critical care medicine, 2021, 04-01, Volume: 203, Issue:7

    Topics: Budesonide; Double-Blind Method; Formoterol Fumarate; Glycopyrrolate; Humans; Pulmonary Disease, Chronic Obstructive

2021
Triple-Therapy Trials for Chronic Obstructive Pulmonary Disease: Methodological Considerations in the Mortality Effect.
    American journal of respiratory and critical care medicine, 2021, 04-01, Volume: 203, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Budesonide; Drug Combinations; Female; Formoterol Fumarate; Glycopyrrolate; Humans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2021
Mortality in ETHOS: A Question of "Power".
    American journal of respiratory and critical care medicine, 2021, 04-01, Volume: 203, Issue:7

    Topics: Budesonide; Double-Blind Method; Formoterol Fumarate; Glycopyrrolate; Humans; Pulmonary Disease, Chronic Obstructive

2021
TRICOP - A Real-world effectiveness study with a single-inhaler extrafine triple therapy over 52 weeks in Austrian patients with COPD.
    Respiratory medicine, 2021, Volume: 182

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Austria; Beclomethasone; Disease Progression; Drug Therapy, Combination; Female; Formoterol Fumarate; Glycopyrrolate; Humans; Male; Middle Aged; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Time Factors; Treatment Outcome

2021
Comparative Effectiveness and Safety of Different Types of Inhaled Long-Acting β
    Chest, 2021, Volume: 160, Issue:4

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Aged; Beclomethasone; Benzyl Alcohols; Budesonide, Formoterol Fumarate Drug Combination; Chlorobenzenes; Cohort Studies; Comparative Effectiveness Research; Disease Progression; Drug Combinations; Female; Fluticasone-Salmeterol Drug Combination; Formoterol Fumarate; Glucocorticoids; Glycopyrrolate; Humans; Indans; Male; Muscarinic Antagonists; Pneumonia; Propensity Score; Proportional Hazards Models; Pulmonary Disease, Chronic Obstructive; Quinolones; Quinuclidines

2021
Effects of indacaterol on the LPS-evoked changes in fluid secretion rate and pH in swine tracheal membrane.
    Pflugers Archiv : European journal of physiology, 2021, Volume: 473, Issue:6

    Topics: Acetylcholine; Adrenergic beta-2 Receptor Agonists; Animals; Bicarbonates; Bronchodilator Agents; Cell Line, Tumor; Cells, Cultured; Cystic Fibrosis Transmembrane Conductance Regulator; Glycopyrrolate; Humans; Hydrogen-Ion Concentration; Indans; Lipopolysaccharides; Mucins; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Respiratory Mucosa; Swine; Trachea

2021
Effects of (a Combination of) the Beta
    Cells, 2021, 05-18, Volume: 10, Issue:5

    Topics: Adrenergic beta-2 Receptor Agonists; Animals; Bronchoconstriction; Bronchodilator Agents; Case-Control Studies; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Glycopyrrolate; Guinea Pigs; Humans; Indans; Lung; Male; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Receptor, Muscarinic M3; Receptors, Adrenergic, beta-2

2021
Cost-Utility Analysis of Fixed-Dose Combination of Indacaterol Acetate Glycopyrronium Bromide and Mometasone Furoate as a Maintenance Treatment in Adult Patients with Asthma Not Adequately Controlled with a Maintenance Combination of a Long-Acting Beta-Ag
    Clinical drug investigation, 2021, Volume: 41, Issue:9

    Topics: Acetates; Adrenal Cortex Hormones; Adult; Asthma; Bronchodilator Agents; Cost-Benefit Analysis; Drug Combinations; Glycopyrrolate; Humans; Indans; Mometasone Furoate; Pulmonary Disease, Chronic Obstructive; Quality of Life; Quinolones; Treatment Outcome

2021
Two cases of chronic obstructive pulmonary disease evaluated by dynamic-ventilatory digital radiography for pulmonary function and assessment of treatment efficacy.
    Respiratory investigation, 2021, Volume: 59, Issue:6

    Topics: Aged; Asthma; Bronchodilator Agents; Drug Combinations; Fluticasone; Formoterol Fumarate; Glycopyrrolate; Humans; Indans; Lung; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Radiographic Image Enhancement; Radiography, Thoracic; Spirometry; Tiotropium Bromide; Treatment Outcome

2021
GFF MDI for the improvement of lung function in COPD - A look at the PINNACLE-1 and PINNACLE-2 data and beyond.
    Expert review of clinical pharmacology, 2017, Volume: 10, Issue:7

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Delayed-Action Preparations; Drug Combinations; Drug Delivery Systems; Formoterol Fumarate; Glycopyrrolate; Humans; Metered Dose Inhalers; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2017
In vitro dose comparison of Respimat
    International journal of chronic obstructive pulmonary disease, 2017, Volume: 12

    Topics: Administration, Inhalation; Androstadienes; Benzyl Alcohols; Bronchodilator Agents; Chlorobenzenes; Computer Simulation; Drug Combinations; Dry Powder Inhalers; Equipment Design; Glycopyrrolate; Humans; Hydrodynamics; Lung; Metered Dose Inhalers; Models, Anatomic; Muscarinic Antagonists; Pharynx; Pulmonary Disease, Chronic Obstructive; Respiration; Severity of Illness Index; Tiotropium Bromide; Tropanes

2017
Glycopyrrolate (Seebri Neohaler) for Maintenance Therapy in Patients with COPD.
    American family physician, 2017, Sep-15, Volume: 96, Issue:6

    Topics: Administration, Inhalation; Glycopyrrolate; Humans; Maintenance Chemotherapy; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2017
GOLD 2017 treatment pathways in 'real life': An analysis of the DACCORD observational study.
    Respiratory medicine, 2017, Volume: 131

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Aged; Critical Pathways; Disease Management; Disease Progression; Drug Combinations; Drug Therapy, Combination; Female; Germany; Glycopyrrolate; Humans; Indans; Longitudinal Studies; Maintenance Chemotherapy; Male; Middle Aged; Muscarinic Antagonists; Practice Guidelines as Topic; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Quinolones

2017
Drug Delivery from an Innovative LAMA/LABA Co-suspension Delivery Technology Fixed-Dose Combination MDI: Evidence of Consistency, Robustness, and Reliability.
    AAPS PharmSciTech, 2018, Volume: 19, Issue:2

    Topics: Administration, Inhalation; Aerosols; Bronchodilator Agents; Double-Blind Method; Drug Delivery Systems; Formoterol Fumarate; Glycopyrrolate; Humans; Inventions; Metered Dose Inhalers; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Reproducibility of Results; Suspensions

2018
[Evaluation of effect of indacaterol (Onbrez) and/or glycopyrronium (Seebri) treatment on Quality of Life of COPD patients in medical practice in Poland - observational study (OSQO)].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2017, Oct-23, Volume: 43, Issue:256

    Topics: Aged; Drug Therapy, Combination; Female; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Poland; Pulmonary Disease, Chronic Obstructive; Quality of Life; Quinolones; Treatment Outcome

2017
In Vitro Characterization of the eFlow Closed System Nebulizer with Glycopyrrolate Inhalation Solution.
    Journal of aerosol medicine and pulmonary drug delivery, 2018, Volume: 31, Issue:3

    Topics: Administration, Inhalation; Aerosols; Glycopyrrolate; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Solutions

2018
Relationship between lung function and inhalation devices for LAMA/LABA therapy for chronic obstructive pulmonary disease.
    Chronic respiratory disease, 2018, Volume: 15, Issue:4

    Topics: Adrenergic beta-2 Receptor Agonists; Aged; Aged, 80 and over; Benzoxazines; Delayed-Action Preparations; Drug Combinations; Dry Powder Inhalers; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Male; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Tiotropium Bromide; Vital Capacity

2018
Single inhaler triple therapy for COPD.
    Drug and therapeutics bulletin, 2017, Volume: 55, Issue:12

    Topics: Beclomethasone; Drug Combinations; Formoterol Fumarate; Glycopyrrolate; Humans; Medication Adherence; Nebulizers and Vaporizers; Practice Guidelines as Topic; Pulmonary Disease, Chronic Obstructive

2017
Cost-effectiveness of indacaterol/glycopyrronium in comparison with salmeterol/fluticasone combination for patients with moderate-to-severe chronic obstructive pulmonary disease: a LANTERN population analysis from Singapore.
    Singapore medical journal, 2018, Volume: 59, Issue:7

    Topics: Aged; Bronchodilator Agents; Cohort Studies; Computer Simulation; Cost-Benefit Analysis; Drug Combinations; Drug Costs; Female; Fluticasone-Salmeterol Drug Combination; Forced Expiratory Volume; Glycopyrrolate; Hospitals; Humans; Indans; Male; Middle Aged; Probability; Pulmonary Disease, Chronic Obstructive; Quality-Adjusted Life Years; Quinolones; Singapore

2018
Nebulized glycopyrrolate (Lonhala Magnair) for COPD.
    The Medical letter on drugs and therapeutics, 2018, 04-23, Volume: 60, Issue:1543

    Topics: Administration, Inhalation; Bronchodilator Agents; Glycopyrrolate; Humans; Lung; Muscarinic Antagonists; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2018
Comparison of glycopyrronium versus tiotropium on the time to clinically important deteriorations in patients with COPD: a post-hoc analysis of randomized trials.
    NPJ primary care respiratory medicine, 2018, 05-24, Volume: 28, Issue:1

    Topics: Administration, Inhalation; Aged; Cholinergic Antagonists; Delayed-Action Preparations; Female; Follow-Up Studies; Glycopyrrolate; Humans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Severity of Illness Index; Tiotropium Bromide; Treatment Outcome; Vital Capacity

2018
Single inhaler triple therapy with extrafine beclomethasone, formoterol, and glycopyrronium for the treatment of chronic obstructive pulmonary disease.
    Expert opinion on pharmacotherapy, 2018, Volume: 19, Issue:11

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Beclomethasone; Drug Therapy, Combination; Formoterol Fumarate; Glycopyrrolate; Humans; Pulmonary Disease, Chronic Obstructive

2018
Symptomatic COPD: is it time for triple therapy?
    The Lancet. Respiratory medicine, 2018, Volume: 6, Issue:10

    Topics: Bronchodilator Agents; Budesonide; Double-Blind Method; Formoterol Fumarate; Glycopyrrolate; Humans; Pulmonary Disease, Chronic Obstructive

2018
Indacaterol/Glycopyrronium versus Salmeterol/Fluticasone in Patients with COPD-A Cost-Effectiveness Analysis in the Czech Republic.
    Value in health regional issues, 2018, Volume: 16

    Topics: Bronchodilator Agents; Cost-Benefit Analysis; Czech Republic; Female; Fluticasone-Salmeterol Drug Combination; Glycopyrrolate; Humans; Indans; Male; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quality-Adjusted Life Years; Quinolones

2018
Morbidity and mortality in a population of patients affected by heart failure and chronic obstructive pulmonary disease: an observational study.
    BMC cardiovascular disorders, 2019, 01-16, Volume: 19, Issue:1

    Topics: Adrenergic beta-2 Receptor Agonists; Aged; Aged, 80 and over; Bronchodilator Agents; Comorbidity; Drug Combinations; Female; Glycopyrrolate; Heart Failure; Heart Ventricles; Humans; Indans; Italy; Lung; Male; Middle Aged; Muscarinic Antagonists; Patient Readmission; Pulmonary Disease, Chronic Obstructive; Quinolones; Recovery of Function; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome

2019
Improvement in health status with once-daily indacaterol/glycopyrronium 110/50 μg in COPD patients: real-world evidence from an observational study in Ireland.
    Irish journal of medical science, 2019, Volume: 188, Issue:4

    Topics: Adrenergic beta-2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Drug Combinations; Female; Glycopyrrolate; Health Status; Humans; Indans; Ireland; Male; Middle Aged; Muscarinic Antagonists; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Quinolones; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome

2019
Glycopyrrolate (Lonhala Magnair) for Treatment of Chronic Obstructive Pulmonary Disease.
    American family physician, 2019, 05-15, Volume: 99, Issue:10

    Topics: Administration, Inhalation; Bronchodilator Agents; Forced Expiratory Volume; Glycopyrrolate; Humans; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2019
Effect of smoking status on lung function, patient-reported outcomes, and safety among patients with COPD treated with indacaterol/glycopyrrolate: Pooled analysis of the FLIGHT1 and FLIGHT2 studies.
    Respiratory medicine, 2019, Volume: 155

    Topics: Adult; Aged; Aged, 80 and over; Drug Therapy, Combination; Female; Glycopyrrolate; Humans; Indans; Lung; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Safety; Smoking; Treatment Outcome

2019
Determination of the pharmacokinetics of glycopyrronium in the lung using a population pharmacokinetic modelling approach.
    British journal of clinical pharmacology, 2013, Volume: 76, Issue:6

    Topics: Absorption; Administration, Inhalation; Biological Availability; Charcoal; Computer Simulation; Drug Administration Schedule; Glycopyrrolate; Healthy Volunteers; Humans; Injections, Intravenous; Lung; Models, Biological; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2013
Novartis found to be in breach of code over drug brochure.
    BMJ (Clinical research ed.), 2013, Jun-21, Volume: 346

    Topics: Advertising; Codes of Ethics; Disease Progression; Drug Industry; Drug Labeling; Female; Glycopyrrolate; Humans; Male; Pamphlets; Practice Guidelines as Topic; Pulmonary Disease, Chronic Obstructive

2013
Pipeline for COPD drugs flows with combination candidates.
    Nature medicine, 2013, Volume: 19, Issue:9

    Topics: Bronchodilator Agents; Drug Combinations; Glycopyrrolate; Humans; Indans; Pulmonary Disease, Chronic Obstructive; Quinolones

2013
"All I want for christmas is two": the advent of novel fixed-combination inhalers for COPD and outlook for 2014.
    Advances in therapy, 2013, Volume: 30, Issue:12

    Topics: Administration, Inhalation; Benzyl Alcohols; Bronchodilator Agents; Chlorobenzenes; Delayed-Action Preparations; Drug Administration Schedule; Drug Combinations; Forecasting; Glycopyrrolate; Humans; Nebulizers and Vaporizers; Patient Satisfaction; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2013
Future of fixed-dose longacting β2-agonist and antimuscarinic combination therapy in COPD.
    The Lancet. Respiratory medicine, 2013, Volume: 1, Issue:1

    Topics: Albuterol; Androstadienes; Bronchodilator Agents; Drug Combinations; Female; Fluticasone-Salmeterol Drug Combination; Glucocorticoids; Glycopyrrolate; Humans; Indans; Male; Pulmonary Disease, Chronic Obstructive; Quinolones; Sympathomimetics

2013
Inhalation of glycopyrronium inhibits cigarette smoke-induced acute lung inflammation in a murine model of COPD.
    International immunopharmacology, 2014, Volume: 18, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Glycopyrrolate; Lymphocytes; Macrophages; Matrix Metalloproteinase 9; Mice; Mice, Inbred ICR; Muscarinic Antagonists; Neutrophils; Nicotiana; Oxidative Stress; Pneumonia; Pulmonary Disease, Chronic Obstructive; Smoke; Tissue Inhibitor of Metalloproteinase-1

2014
COPD treatment: time to change our algorithm?
    The Lancet. Respiratory medicine, 2013, Volume: 1, Issue:3

    Topics: Drug Combinations; Female; Glycopyrrolate; Humans; Indans; Male; Pulmonary Disease, Chronic Obstructive; Quinolones; Respiratory System; Scopolamine Derivatives; Tiotropium Bromide

2013
2013 American Thoracic Society International Conference.
    The Lancet. Respiratory medicine, 2013, Volume: 1, Issue:5

    Topics: alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Analgesics, Non-Narcotic; Asthma; Benzamides; Clofazimine; Congresses as Topic; Cyclobutanes; Drug Combinations; Glycopyrrolate; Hospital Mortality; Humans; Indans; Intensive Care Units; Lung; Pulmonary Disease, Chronic Obstructive; Quinolones; Societies, Medical; Thoracic Diseases; Treatment Outcome; Tuberculosis, Multidrug-Resistant; United States

2013
QVA149 versus glycopyrronium for COPD.
    The Lancet. Respiratory medicine, 2013, Volume: 1, Issue:5

    Topics: Female; Glycopyrrolate; Humans; Indans; Male; Pulmonary Disease, Chronic Obstructive; Quinolones; Respiratory System; Scopolamine Derivatives

2013
QVA149 versus glycopyrronium for COPD - authors' reply.
    The Lancet. Respiratory medicine, 2013, Volume: 1, Issue:5

    Topics: Female; Glycopyrrolate; Humans; Indans; Male; Pulmonary Disease, Chronic Obstructive; Quinolones; Respiratory System; Scopolamine Derivatives

2013
[Glycopyrronium, by inhalation and oral administration (Seebri)].
    Journal de pharmacie de Belgique, 2013, Issue:4

    Topics: Administration, Inhalation; Administration, Oral; Bronchodilator Agents; Glycopyrrolate; Humans; Pulmonary Disease, Chronic Obstructive

2013
Indacaterol for the treatment of chronic obstructive pulmonary disease.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:1

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Drug Administration Schedule; Drug Combinations; Glycopyrrolate; Humans; Indans; Pulmonary Disease, Chronic Obstructive; Quality of Life; Quinolones; Scopolamine Derivatives; Tiotropium Bromide; Treatment Outcome

2015
Cardiovascular safety of two bronchodilators' fixed-dose combination: indacaterol and glycopyrronium.
    Pneumonologia i alergologia polska, 2015, Volume: 83, Issue:2

    Topics: Adjuvants, Anesthesia; Administration, Inhalation; Bronchodilator Agents; Cardiovascular System; Clinical Trials as Topic; Drug Combinations; Glycopyrrolate; Humans; Indans; Pulmonary Disease, Chronic Obstructive; Quinolones

2015
Triple inhaler therapy for COPD.
    Thorax, 2015, Volume: 70, Issue:10

    Topics: Albuterol; Androstadienes; Bronchodilator Agents; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Male; Pulmonary Disease, Chronic Obstructive; Scopolamine Derivatives

2015
Safety of inhaled glycopyrronium in patients with COPD: a comprehensive analysis of clinical studies and post-marketing data.
    International journal of chronic obstructive pulmonary disease, 2015, Volume: 10

    Topics: Administration, Inhalation; Aged; Aged, 80 and over; Bronchodilator Agents; Female; Glycopyrrolate; Humans; Lung; Male; Middle Aged; Muscarinic Antagonists; Nebulizers and Vaporizers; Patient Safety; Product Surveillance, Postmarketing; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome

2015
Cost-Effectiveness of Glycopyrronium Bromide Compared with Tiotropium in Patients with Chronic Obstructive Pulmonary Disease in Sweden.
    Applied health economics and health policy, 2015, Volume: 13, Issue:6

    Topics: Bronchodilator Agents; Cost-Benefit Analysis; Female; Forced Expiratory Volume; Glycopyrrolate; Humans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Sweden; Tiotropium Bromide

2015
[Too positive and uncritical dissemination of Glycopyrronium].
    Ugeskrift for laeger, 2013, Nov-04, Volume: 175, Issue:45

    Topics: Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2013
[Reply: Good with options].
    Ugeskrift for laeger, 2013, Nov-04, Volume: 175, Issue:45

    Topics: Glycopyrrolate; Humans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2013
Low Doses of Long-Acting β-Agonists/Long-Acting Muscarinic Agents with Large Effects. The FLIGHT Study.
    American journal of respiratory and critical care medicine, 2015, Nov-01, Volume: 192, Issue:9

    Topics: Female; Glycopyrrolate; Humans; Indans; Male; Pulmonary Disease, Chronic Obstructive; Quinolones

2015
Response to: impact of tiotropium on exacerbations versus glycopyrronium and QVA149.
    Expert review of respiratory medicine, 2015, Volume: 9, Issue:6

    Topics: Bronchodilator Agents; Glycopyrrolate; Humans; Lung; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2015
Impact of tiotropium on exacerbations versus glycopyrronium and QVA149.
    Expert review of respiratory medicine, 2015, Volume: 9, Issue:6

    Topics: Bronchodilator Agents; Glycopyrrolate; Humans; Lung; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2015
[Good bronchial dilatation helps keep patients physically active].
    MMW Fortschritte der Medizin, 2016, Mar-17, Volume: 158, Issue:5

    Topics: Bronchodilator Agents; Clinical Trials as Topic; Drug Combinations; Glycopyrrolate; Humans; Indans; Motor Activity; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Quinolones

2016
Seebri Neohaler and Utibron Neohaler for COPD.
    The Medical letter on drugs and therapeutics, 2016, Mar-28, Volume: 58, Issue:1491

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Drug Administration Schedule; Drug Combinations; Drug Interactions; Female; Glycopyrrolate; Humans; Indans; Lung; Male; Muscarinic Antagonists; Nebulizers and Vaporizers; Pregnancy; Pulmonary Disease, Chronic Obstructive; Quinolones; Risk Factors; Treatment Outcome

2016
Population pharmacokinetics of IND/GLY (indacaterol/glycopyrronium) in COPD patients.
    International journal of clinical pharmacology and therapeutics, 2016, Volume: 54, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Drug Combinations; Female; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Models, Biological; Pulmonary Disease, Chronic Obstructive; Quinolones

2016
[Narrowing indications for inhaled steroids in COPD].
    MMW Fortschritte der Medizin, 2016, May-12, Volume: 158, Issue:9

    Topics: Bronchodilator Agents; Clinical Trials as Topic; Disease Progression; Drug Combinations; Glycopyrrolate; Humans; Indans; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Quinolones

2016
[UBC internal medicine returns to the respiratory tract area].
    MMW Fortschritte der Medizin, 2016, May-12, Volume: 158, Issue:9

    Topics: Bronchodilator Agents; Drug Combinations; Glycopyrrolate; Humans; Indans; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Quinolones

2016
Another Choice for Prevention of COPD Exacerbations.
    The New England journal of medicine, 2016, Jun-09, Volume: 374, Issue:23

    Topics: Adrenergic beta-2 Receptor Agonists; Female; Fluticasone-Salmeterol Drug Combination; Glucocorticoids; Glycopyrrolate; Humans; Indans; Male; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones

2016
A case report of QT prolongation with glycopyrronium bromide in a patient with chronic tamoxifen use.
    BMC research notes, 2016, Jun-14, Volume: 9

    Topics: Administration, Inhalation; Aged; Electrocardiography; Female; Glycopyrrolate; Humans; Long QT Syndrome; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Selective Estrogen Receptor Modulators; Syncope; Tamoxifen

2016
Cost Effectiveness of the Long-Acting β2-Adrenergic Agonist (LABA)/Long-Acting Muscarinic Antagonist Dual Bronchodilator Indacaterol/Glycopyrronium Versus the LABA/Inhaled Corticosteroid Combination Salmeterol/Fluticasone in Patients with Chronic Obstruct
    Applied health economics and health policy, 2016, Volume: 14, Issue:5

    Topics: Administration, Inhalation; Aged; Bronchodilator Agents; Canada; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Fluticasone; France; Glycopyrrolate; Health Care Costs; Humans; Indans; Italy; Male; Portugal; Pulmonary Disease, Chronic Obstructive; Quinolones; Salmeterol Xinafoate

2016
Formoterol fumarate + glycopyrrolate for the treatment of chronic obstructive pulmonary disease.
    Expert review of respiratory medicine, 2016, Volume: 10, Issue:10

    Topics: Administration, Inhalation; Bronchodilator Agents; Drug Combinations; Formoterol Fumarate; Glycopyrrolate; Humans; Metered Dose Inhalers; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive

2016
Indacaterol-Glycopyrronium for COPD.
    The New England journal of medicine, 2016, 09-01, Volume: 375, Issue:9

    Topics: Bronchodilator Agents; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Treatment Outcome

2016
Indacaterol-Glycopyrronium for COPD.
    The New England journal of medicine, 2016, 09-01, Volume: 375, Issue:9

    Topics: Bronchodilator Agents; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Treatment Outcome

2016
Indacaterol-Glycopyrronium for COPD.
    The New England journal of medicine, 2016, 09-01, Volume: 375, Issue:9

    Topics: Bronchodilator Agents; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Treatment Outcome

2016
Indacaterol-Glycopyrronium for COPD.
    The New England journal of medicine, 2016, 09-01, Volume: 375, Issue:9

    Topics: Bronchodilator Agents; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Treatment Outcome

2016
Glycopyrrolate/formoterol (Bevespi Aerosphere) for COPD.
    The Medical letter on drugs and therapeutics, 2016, Oct-10, Volume: 58, Issue:1505

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Aerosols; Bronchodilator Agents; Drug Administration Schedule; Drug Combinations; Drug Interactions; Formoterol Fumarate; Glycopyrrolate; Humans; Lung; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Treatment Outcome

2016
Indacaterol/glycopyrronium in symptomatic patients with COPD (GOLD B and GOLD D) versus salmeterol/fluticasone: ILLUMINATE/LANTERN pooled analysis.
    International journal of chronic obstructive pulmonary disease, 2016, Volume: 11

    Topics: Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; Clinical Trials, Phase III as Topic; Female; Fluticasone-Salmeterol Drug Combination; Forced Expiratory Volume; Glycopyrrolate; Humans; Indans; Lung; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Randomized Controlled Trials as Topic; Recovery of Function; Severity of Illness Index; Spirometry; Surveys and Questionnaires; Time Factors; Treatment Outcome; Vital Capacity

2016
Combination of glycopyrronium and indacaterol inhibits carbachol-induced ERK5 signal in fibrotic processes.
    Respiratory research, 2017, 03-11, Volume: 18, Issue:1

    Topics: Adrenergic beta-2 Receptor Antagonists; Aged; Carbachol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glycopyrrolate; Humans; Indans; Male; Middle Aged; Mitogen-Activated Protein Kinase 7; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Pulmonary Fibrosis; Quinolones; Signal Transduction; Treatment Outcome

2017
Comparative characterization of lung muscarinic receptor binding after intratracheal administration of tiotropium, ipratropium, and glycopyrrolate.
    Journal of pharmacological sciences, 2011, Volume: 115, Issue:3

    Topics: Animals; Binding Sites; Bronchodilator Agents; Glycopyrrolate; Heart; Ipratropium; Lung; Male; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland; Tiotropium Bromide; Trachea; Urinary Bladder

2011