glycolic acid has been researched along with Skin Aging in 54 studies
glycolic acid: RN given refers to parent cpd
glycolic acid : A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
Skin Aging: The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The gel containing retinoic acid and glycolic acid showed significant improvements of the clinical signs of severe skin aging with a concomitant improvement of epidermal and dermal structures evaluated via RCM." | 8.02 | Clinical efficacy and reflectance confocal microscopy monitoring in moderate-severe skin aging treated with a polyvinyl gel containing retinoic and glycolic acid: An assessor-blinded 1-month study proof-of-concept trial. ( Bianchi, L; Campione, E; Cosio, T; Dika, E; Lanna, C; Mazzilli, S, 2021) |
| " Both medium-depth chemical peels including 15% TCA in combination with 70% GA and 35% TCA alone proved to be useful for the removal of epidermal or superficial lesions and to improve the texture of photodamaged facial skin (grade II-III Glogau photoaged skin)." | 2.94 | Comparative study of 15% trichloroacetic acid peel combined with 70% glycolic acid and 35% trichloroacetic acid peel for the treatment of photodamaged facial skin in aging women. ( Kubiak, M; Mucha, P; Rotsztejn, H, 2020) |
| "A major cause of skin aging is a chronic microinflammation created by environmental conditions and ultraviolet exposures." | 2.72 | Use of nonthermal blue (405- to 420-nm) and near-infrared light (850- to 900-nm) dual-wavelength system in combination with glycolic acid peels and topical vitamin C for skin photorejuvenation. ( Fournier, N; Fritz, K; Mordon, S, 2006) |
| "Hydroquinone 4% cream with 2% glycolic acid is safe and effective in improving photodamage on the neck and upper chest when used alone or in combination with salicylic acid peels." | 2.69 | Efficacy of hydroquinone cream (USP 4%) used alone or in combination with salicylic acid peels in improving photodamage on the neck and upper chest. ( Gladstone, HB; Jeffers, M; Moy, RL; Nguyen, SL; Ottomeyer, T; Williams, R; Wortzman, M, 2000) |
| "Glycolic acid has been one of the more commonly used alpha hydroxy acids for the treatment of photodamaged skin." | 2.68 | Short contact 70% glycolic acid peels as a treatment for photodamaged skin. A pilot study. ( Andree, C; Dobry, M; Grove, G; Hollenbach, KA; Hunt, S; Piacquadio, D, 1996) |
| "L-Lactic acid cream was significantly superior to the vehicle in reducing the overall severity of photodamage (P < ." | 2.68 | Topical 8% glycolic acid and 8% L-lactic acid creams for the treatment of photodamaged skin. A double-blind vehicle-controlled clinical trial. ( Bartolone, J; Drake, LA; Gillies, R; Kollias, N; Smith, S; Stern, R; Stiller, MJ, 1996) |
| "Glycolic acid is a member of the AHA family, which occurs naturally in foods and has been used for centuries as a cutaneous rejuvenation treatment." | 2.39 | The use of glycolic acid as a peeling agent. ( Murad, H; Premo, PS; Shamban, AT, 1995) |
| "Glycolic acid treatment is believed to reverse the photoaging process by increasing collagen synthesis in the skin." | 1.30 | Increased in vivo collagen synthesis and in vitro cell proliferative effect of glycolic acid. ( Kim, DH; Kim, SJ; Maibach, HI; Park, JH; Won, YH, 1998) |
| "Glycolic acid is an alpha hydroxyacid that is useful as a chemical peeling agent." | 1.29 | Glycolic acid peels for the treatment of wrinkles and photoaging. ( Moy, LS; Moy, RL; Murad, H, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 23 (42.59) | 18.2507 |
| 2000's | 15 (27.78) | 29.6817 |
| 2010's | 12 (22.22) | 24.3611 |
| 2020's | 4 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Chernoff, G | 1 |
| Kubiak, M | 2 |
| Mucha, P | 2 |
| Rotsztejn, H | 2 |
| Campione, E | 1 |
| Cosio, T | 1 |
| Lanna, C | 1 |
| Mazzilli, S | 1 |
| Dika, E | 1 |
| Bianchi, L | 1 |
| Bhattacharyya, TK | 2 |
| Bueller, H | 1 |
| Hsia, Y | 1 |
| Thomas, JR | 2 |
| Rouvrais, C | 1 |
| Baspeyras, M | 1 |
| Mengeaud, V | 1 |
| Rossi, AB | 1 |
| Maidhof, R | 1 |
| Liebel, F | 1 |
| Hwang, C | 1 |
| Ruvolo, E | 1 |
| Lyga, J | 1 |
| Tang, SC | 1 |
| Tang, LC | 1 |
| Liu, CH | 1 |
| Liao, PY | 1 |
| Lai, JC | 1 |
| Yang, JH | 1 |
| Santos-Caetano, JP | 1 |
| Vila, R | 1 |
| Gfeller, CF | 1 |
| Cargill, M | 1 |
| Mahalingam, H | 1 |
| Dębowska, R | 1 |
| Mekas, M | 1 |
| Chwalek, J | 1 |
| MacGregor, J | 1 |
| Chapas, A | 1 |
| Wakade, DV | 1 |
| Nayak, CS | 1 |
| Bhatt, KD | 1 |
| Barros, BS | 1 |
| Zaenglein, AL | 1 |
| Khunger, N | 1 |
| Oresajo, C | 1 |
| Yatskayer, M | 1 |
| Hansenne, I | 1 |
| Abdel-Daim, M | 2 |
| Funasaka, Y | 3 |
| Kamo, T | 2 |
| Ooe, M | 2 |
| Matsunaka, H | 2 |
| Yanagita, E | 2 |
| Itoh, T | 2 |
| Nishigori, C | 2 |
| Kassim, AT | 1 |
| Hussain, M | 1 |
| Goldberg, DJ | 1 |
| Dixon, TK | 1 |
| Fuchs, KO | 1 |
| Solis, O | 1 |
| Tapawan, R | 1 |
| Paranjpe, J | 1 |
| Rubino, C | 1 |
| Farace, F | 1 |
| Dessy, LA | 1 |
| Sanna, MP | 1 |
| Mazzarello, V | 1 |
| Yamamoto, Y | 1 |
| Uede, K | 1 |
| Yonei, N | 1 |
| Kishioka, A | 1 |
| Ohtani, T | 1 |
| Furukawa, F | 1 |
| Fournier, N | 1 |
| Fritz, K | 1 |
| Mordon, S | 1 |
| Rendon, MI | 1 |
| Effron, C | 1 |
| Edison, BL | 1 |
| Bertin, C | 1 |
| Zunino, H | 1 |
| Lanctin, M | 1 |
| Stamatas, GN | 1 |
| Camel, E | 1 |
| Robert, C | 1 |
| Issachar, N | 1 |
| Murad, H | 2 |
| Shamban, AT | 1 |
| Premo, PS | 1 |
| Matarasso, SL | 1 |
| Glogau, RG | 1 |
| Markey, AC | 1 |
| Moy, LS | 2 |
| Moy, RL | 3 |
| Clark, CP | 2 |
| Piacquadio, D | 2 |
| Dobry, M | 1 |
| Hunt, S | 1 |
| Andree, C | 1 |
| Grove, G | 1 |
| Hollenbach, KA | 1 |
| Newman, N | 1 |
| Newman, A | 1 |
| Babapour, R | 1 |
| Harris, AG | 1 |
| Brody, H | 1 |
| Coleman, WP | 1 |
| Perricone, NV | 1 |
| Elson, ML | 1 |
| Harris, D | 1 |
| Ditre, CM | 2 |
| Griffin, TD | 1 |
| Murphy, GF | 1 |
| Sueki, H | 1 |
| Telegan, B | 1 |
| Johnson, WC | 1 |
| Yu, RJ | 2 |
| Van Scott, EJ | 1 |
| Stiller, MJ | 1 |
| Bartolone, J | 1 |
| Stern, R | 1 |
| Smith, S | 1 |
| Kollias, N | 2 |
| Gillies, R | 1 |
| Drake, LA | 1 |
| Piérard, GE | 1 |
| Henry, F | 1 |
| Piérard-Franchimont, C | 1 |
| Tse, Y | 1 |
| Ostad, A | 1 |
| Lee, HS | 1 |
| Levine, VJ | 1 |
| Koenig, K | 1 |
| Kamino, H | 1 |
| Ashinoff, R | 1 |
| Hanke, CW | 1 |
| Bullock, SS | 1 |
| Ellis, DA | 1 |
| Tan, AK | 1 |
| Ellis, CS | 1 |
| Apfelberg, DB | 1 |
| Vidt, DG | 1 |
| Bergfeld, WF | 1 |
| Bergfeld, W | 1 |
| Tung, R | 1 |
| Vidimos, A | 1 |
| Vellanki, L | 1 |
| Remzi, B | 1 |
| Stanton-Hicks, U | 1 |
| Bernstein, EF | 3 |
| Underhill, CB | 1 |
| Lakkakorpi, J | 1 |
| Uitto, J | 1 |
| Scott, EV | 1 |
| Kligman, AM | 1 |
| Thibault, PK | 1 |
| Wlodarczyk, J | 1 |
| Wenck, A | 1 |
| Kim, SJ | 1 |
| Park, JH | 1 |
| Kim, DH | 1 |
| Won, YH | 1 |
| Maibach, HI | 1 |
| Moon, SE | 1 |
| Park, SB | 1 |
| Ahn, HT | 1 |
| Youn, JI | 1 |
| Gladstone, HB | 1 |
| Nguyen, SL | 1 |
| Williams, R | 1 |
| Ottomeyer, T | 1 |
| Wortzman, M | 1 |
| Jeffers, M | 1 |
| Butler, PE | 1 |
| Gonzalez, S | 1 |
| Randolph, MA | 1 |
| Kim, J | 1 |
| Yaremchuk, MJ | 1 |
| Fischer, TW | 1 |
| Elsner, P | 1 |
| Lee, J | 1 |
| Brown, DB | 1 |
| Yu, R | 1 |
| Van Scott, E | 1 |
| Sato, H | 1 |
| Usuki, A | 1 |
| Ohashi, A | 1 |
| Kotoya, H | 1 |
| Miyamoto, K | 1 |
| Hillebrand, GG | 1 |
| Ichihashi, M | 1 |
| Isoda, M | 1 |
| Ueda, S | 1 |
| Imayama, S | 1 |
| Tsukahara, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Efficacy of Combined Peels in Treatment of Melasma Using Modified Jessner's Solution With 20%Trichloroacetic Acid Versus 70%Glycolic Acid With 20% Trichloroacetic Acid : A Split-face Study[NCT03153852] | Phase 4 | 30 participants (Anticipated) | Interventional | 2018-03-15 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for glycolic acid and Skin Aging
| Article | Year |
|---|---|
The Use of Cosmeceuticals in Acne: Help or Hoax?
Topics: Acne Vulgaris; Complementary Therapies; Contraindications; Cosmeceuticals; Deception; Glycolates; Hu | 2017 |
Effects of topicals on the aging skin process.
Topics: Administration, Topical; Ascorbic Acid; Glycolates; Humans; Peptides; Retinoids; Skin Absorption; Sk | 2013 |
The use of fillers and botulinum toxin type A in combination with superficial glycolic acid (alpha-hydroxy acid) peels: optimizing injection therapy with the skin-smoothing properties of peels.
Topics: Botulinum Toxins, Type A; Chemexfoliation; Combined Modality Therapy; Dermabrasion; Glycolates; Huma | 2007 |
The use of glycolic acid as a peeling agent.
Topics: Chemexfoliation; Dermatologic Surgical Procedures; Drug Combinations; Face; Glycolates; Humans; Pati | 1995 |
Alpha hydroxy acids in skin care.
Topics: Acne Vulgaris; Chemexfoliation; Female; Glycolates; Humans; Hydroxy Acids; Male; Melanosis; Skin Agi | 1996 |
Tretinoin and glycolic acid treatment regimens.
Topics: Chemexfoliation; Clinical Protocols; Dermatologic Surgical Procedures; Glycolates; Humans; Keratolyt | 1995 |
Superficial micropeels: glycolic acid and alpha-hydroxy acid with kojic acid.
Topics: Chemexfoliation; Clinical Protocols; Dermatologic Surgical Procedures; Glycolates; Humans; Hydroxy A | 1995 |
Cosmetic use of alpha-hydroxy acids.
Topics: Beauty Culture; Chemistry, Pharmaceutical; Drug Prescriptions; Glycolates; Humans; Lactic Acid; Nonp | 1997 |
Topical treatments for photoaged skin. Separating the reality from the hype.
Topics: Administration, Topical; Antioxidants; Dermatologic Agents; Glycolates; Humans; Retinoids; Skin Agin | 1997 |
The antioxidative potential of melatonin in the skin.
Topics: Animals; Antioxidants; Ascorbic Acid; Chromans; Dose-Response Relationship, Drug; Dose-Response Rela | 2001 |
Chemical peels.
Topics: Administration, Cutaneous; Chemexfoliation; Esthetics; Female; Follow-Up Studies; Glycolates; Humans | 2002 |
19 trials available for glycolic acid and Skin Aging
| Article | Year |
|---|---|
Comparative study of 15% trichloroacetic acid peel combined with 70% glycolic acid and 35% trichloroacetic acid peel for the treatment of photodamaged facial skin in aging women.
Topics: Administration, Cutaneous; Adult; Caustics; Chemexfoliation; Dose-Response Relationship, Drug; Face; | 2020 |
Antiaging efficacy of a retinaldehyde-based cream compared with glycolic acid peel sessions: A randomized controlled study.
Topics: Adult; Chemexfoliation; Female; Glycolates; Humans; Keratolytic Agents; Middle Aged; Retinaldehyde; | 2018 |
Cosmetic use of three topical moisturizers following glycolic acid facial peels.
Topics: Administration, Cutaneous; Adult; Chemexfoliation; Epidermis; Face; Female; Glycolates; Humans; Male | 2020 |
An Evaluation of Efficacy and Tolerability of Novel Enzyme Exfoliation Versus Glycolic Acid in Photodamage Treatment.
Topics: Administration, Cutaneous; Adult; Aged; Animals; Citric Acid; Dermatologic Agents; Double-Blind Meth | 2015 |
Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin.
Topics: Administration, Cutaneous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemexfoliation; Drug The | 2008 |
Open-label evaluation of the skin-brightening efficacy of a skin-brightening system using decapeptide-12.
Topics: Administration, Cutaneous; Antioxidants; Drug Therapy, Combination; Female; Glycolates; Humans; Hype | 2012 |
The effects of an estrogen and glycolic acid cream on the facial skin of postmenopausal women: a randomized histologic study.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Body Weights and Measures; Dermatologic Age | 2003 |
A prospective study of anti-aging topical therapies using a quantitative method of assessment.
Topics: Adult; Double-Blind Method; Female; Glycolates; Humans; Keratolytic Agents; Microscopy, Electron, Sc | 2005 |
Effects of alpha-hydroxy acids on the human skin of Japanese subjects: the rationale for chemical peeling.
Topics: Acetic Acid; Administration, Cutaneous; Adult; Chemexfoliation; Citric Acid; Drug Administration Sch | 2006 |
Use of nonthermal blue (405- to 420-nm) and near-infrared light (850- to 900-nm) dual-wavelength system in combination with glycolic acid peels and topical vitamin C for skin photorejuvenation.
Topics: Administration, Topical; Adult; Aged; Ascorbic Acid; Female; Glycolates; Humans; Keratolytic Agents; | 2006 |
Combined retinol-lactose-glycolic acid effects on photoaged skin: a double-blind placebo-controlled study.
Topics: Administration, Cutaneous; Adult; Biopsy; Double-Blind Method; Female; Galvanic Skin Response; Glyco | 2008 |
Short contact 70% glycolic acid peels as a treatment for photodamaged skin. A pilot study.
Topics: Adult; Aged; Chemexfoliation; Drug Evaluation; Female; Glycolates; Humans; Male; Middle Aged; Pilot | 1996 |
Clinical improvement of photoaged skin with 50% glycolic acid. A double-blind vehicle-controlled study.
Topics: Adult; Aged; Biopsy; Chemexfoliation; Double-Blind Method; Female; Glycolates; Humans; Male; Microsc | 1996 |
Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study.
Topics: Aged; Aged, 80 and over; Biopsy; Citrates; Citric Acid; Collagen; Elastic Tissue; Epidermis; Female; | 1996 |
Topical 8% glycolic acid and 8% L-lactic acid creams for the treatment of photodamaged skin. A double-blind vehicle-controlled clinical trial.
Topics: Administration, Topical; Adult; Aged; Dosage Forms; Double-Blind Method; Female; Glycolates; Humans; | 1996 |
Comparative effect of short-term topical tretinoin and glycolic acid on mechanical properties of photodamaged facial skin in HRT-treated menopausal women.
Topics: Administration, Topical; Double-Blind Method; Estrogen Replacement Therapy; Estrogens, Conjugated (U | 1996 |
A double-blind randomized clinical trial on the effectiveness of a daily glycolic acid 5% formulation in the treatment of photoaging.
Topics: Administration, Topical; Double-Blind Method; Drug Administration Schedule; Face; Female; Glycolates | 1998 |
Efficacy of hydroquinone cream (USP 4%) used alone or in combination with salicylic acid peels in improving photodamage on the neck and upper chest.
Topics: Chemexfoliation; Female; Glycolates; Humans; Hydroquinones; Hyperpigmentation; Keratolytic Agents; M | 2000 |
The efficacy of glycolic acid for treating wrinkles: analysis using newly developed facial imaging systems equipped with fluorescent illumination.
Topics: Adult; Age Factors; Aged; Face; Glycolates; Humans; Image Processing, Computer-Assisted; Keratolytic | 2001 |
24 other studies available for glycolic acid and Skin Aging
| Article | Year |
|---|---|
Combining topical dermal infused exosomes with injected calcium hydroxylapatite for enhanced tissue biostimulation.
Topics: Administration, Topical; Botulinum Toxins; Combined Modality Therapy; Cosmetic Techniques; Cosmetics | 2023 |
Clinical efficacy and reflectance confocal microscopy monitoring in moderate-severe skin aging treated with a polyvinyl gel containing retinoic and glycolic acid: An assessor-blinded 1-month study proof-of-concept trial.
Topics: Female; Glycolates; Humans; Microscopy, Confocal; Polyvinyls; Prospective Studies; Skin Aging; Treat | 2021 |
Dermal Histology in Mouse Skin Exposed to Cosmeceuticals.
Topics: Animals; Ascorbic Acid; Cosmeceuticals; Estrogens; Female; Glycine max; Glycolates; Mice; Mice, Hair | 2017 |
UV fluorescence excitation spectroscopy as a noninvasive predictor of epidermal proliferation and clinical performance of cosmetic formulations.
Topics: Administration, Cutaneous; Aged; Cell Proliferation; Cosmetics; Epidermis; Female; Fluorescence; Gly | 2019 |
Glycolic acid attenuates UVB-induced aquaporin-3, matrix metalloproteinase-9 expression, and collagen degradation in keratinocytes and mouse skin.
Topics: Administration, Topical; Animals; Aquaporin 3; Collagen; Gene Expression Regulation; Glycolates; Ker | 2019 |
Evaluation of 70% glycolic peels versus 15% trichloroacetic peels for the treatment of photodamaged facial skin in aging women.
Topics: Adult; Chemexfoliation; Cosmetic Techniques; Elasticity; Erythema; Face; Female; Glycolates; Humans; | 2014 |
A Study Comparing the Efficacy of Monopolar Radiofrequency and Glycolic Acid Peels in Facial Rejuvenation of Aging Skin Using Histopathology and Ultrabiomicroscopic Sonography (UBM) - An Evidence Based Study.
Topics: Adult; Chemexfoliation; Electric Stimulation Therapy; Face; Female; Glycolates; Humans; Keratolytic | 2016 |
Standard guidelines of care for chemical peels.
Topics: Acne Vulgaris; Chemexfoliation; Glycolates; Humans; Skin; Skin Aging; Skin Diseases | 2008 |
Preventive effect of chemical peeling on ultraviolet induced skin tumor formation.
Topics: Animals; Chemexfoliation; Cyclooxygenase 2; Dinoprostone; Female; Genes, p53; Glycolates; Mice; Mice | 2010 |
Effect of chemical peeling on photocarcinogenesis.
Topics: Animals; Chemexfoliation; Dinoprostone; Female; Glycolates; Keratolytic Agents; Mice; Mice, Hairless | 2010 |
Wood's lamp for superficial chemical peels.
Topics: Chemexfoliation; Drug Combinations; Ethanol; Female; Fluorescein; Fluoresceins; Glycolates; Humans; | 1994 |
Glycolic acid peels for the treatment of wrinkles and photoaging.
Topics: Chemexfoliation; Face; Female; Glycolates; Humans; Male; Skin Aging | 1993 |
Round table discussion of alpha hydroxy acids.
Topics: Chemexfoliation; Glycolates; Humans; Hydroxy Acids; Research; Skin; Skin Aging; Skin Diseases; Solut | 1996 |
A clinical and histologic evaluation of two medium-depth peels. Glycolic acid versus Jessner's trichloroacetic acid.
Topics: Chemexfoliation; Glycolates; Humans; Keratosis; Male; Prospective Studies; Skin; Skin Aging; Trichlo | 1996 |
Ultrapulse carbon dioxide laser with CPG scanner for full-face resurfacing for rhytids, photoaging, and acne scars.
Topics: Acne Vulgaris; Acyclovir; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antiviral Agents | 1997 |
Improving the cosmetic appearance of photoaged skin with glycolic acid.
Topics: Adult; Chemexfoliation; Female; Glycolates; Humans; Middle Aged; Skin; Skin Aging | 1997 |
Citric acid increases viable epidermal thickness and glycosaminoglycan content of sun-damaged skin.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Atrophy; Biopsy; Chond | 1997 |
Topical drugs for aging skin.
Topics: Administration, Topical; Antioxidants; Ascorbic Acid; Controlled Clinical Trials as Topic; Double-Bl | 1997 |
Increased in vivo collagen synthesis and in vitro cell proliferative effect of glycolic acid.
Topics: Animals; Blotting, Northern; Cell Division; Cells, Cultured; Collagen; Dermatologic Agents; Fibrobla | 1998 |
The effect of glycolic acid on photoaged albino hairless mouse skin.
Topics: Animals; Collagen; Female; Glycolates; Light; Mice; Mice, Hairless; Skin; Skin Aging | 1999 |
Office-based skin care and superficial peels: the scientific rationale.
Topics: Ascorbic Acid; Chemexfoliation; Dermatologic Agents; Drug Combinations; Ethanol; Glycolates; Humans; | 1999 |
Quantitative and qualitative effects of chemical peeling on photo-aged skin: an experimental study.
Topics: Animals; Chemexfoliation; Collagen; Glycolates; Glycosaminoglycans; Mice; Mice, Hairless; Phenol; Sk | 2001 |
Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin.
Topics: Aged; Blotting, Northern; Collagen; Female; Gene Expression; Glycolates; Humans; Hyaluronic Acid; Im | 2001 |
New formulation of chemical peeling agent: histological evaluation in sun-damaged skin model in hairless mice.
Topics: Animals; Elastin; Female; Glycolates; Inflammation; Keratolytic Agents; Mice; Mice, Hairless; Models | 2001 |