glycolic acid has been researched along with Pregnancy in 8 studies
glycolic acid: RN given refers to parent cpd
glycolic acid : A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study sought to determine the relative roles of glycolic acid (GA), a toxicologically important metabolite of ethylene glycol (EG), and metabolic acidosis in causing developmental toxicity in Sprague-Dawley rats." | 7.70 | Ethylene glycol developmental toxicity: unraveling the roles of glycolic acid and metabolic acidosis. ( Carney, EW; Dittenber, DA; Dryzga, MD; Freshour, NL, 1999) |
| "This study sought to determine the relative roles of glycolic acid (GA), a toxicologically important metabolite of ethylene glycol (EG), and metabolic acidosis in causing developmental toxicity in Sprague-Dawley rats." | 3.70 | Ethylene glycol developmental toxicity: unraveling the roles of glycolic acid and metabolic acidosis. ( Carney, EW; Dittenber, DA; Dryzga, MD; Freshour, NL, 1999) |
| " Pharmacokinetic parameters including Cmax, Tmax, AUC, and betat((1/2)) were determined for EG and GA." | 1.31 | Dose-dependent nonlinear pharmacokinetics of ethylene glycol metabolites in pregnant (GD 10) and nonpregnant Sprague-Dawley rats following oral administration of ethylene glycol. ( Bartels, MJ; Carney, EW; Pottenger, LH, 2001) |
| " Clear evidence of maternal toxicity was demonstrated at 600 mg/kg; adverse clinical observations were statistically significantly increased (wheezing/lung noise, abnormal gait/staggering, lethargy)." | 1.30 | Developmental toxicity study of glycolic acid in rats. ( Hurtt, ME; Kennedy, GL; Munley, SM, 1999) |
| "The kojic acid preparation was more irritating." | 1.29 | The combination of glycolic acid and hydroquinone or kojic acid for the treatment of melasma and related conditions. ( Fulton, JE; Garcia, A, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ellis-Hutchings, RG | 1 |
| Moore, NP | 1 |
| Marshall, VA | 1 |
| Rasoulpour, RJ | 1 |
| Carney, EW | 4 |
| Tornesi, B | 1 |
| Liberacki, AB | 1 |
| Markham, DA | 1 |
| Weitz, KK | 1 |
| Luders, TM | 1 |
| Studniski, KG | 1 |
| Blessing, JC | 1 |
| Gies, RA | 1 |
| Corley, RA | 1 |
| Kunisaki, SM | 1 |
| Jennings, RW | 1 |
| Fauza, DO | 1 |
| Garcia, A | 1 |
| Fulton, JE | 1 |
| Freshour, NL | 1 |
| Dittenber, DA | 1 |
| Dryzga, MD | 1 |
| Munley, SM | 1 |
| Kennedy, GL | 1 |
| Hurtt, ME | 1 |
| Pottenger, LH | 1 |
| Bartels, MJ | 1 |
| Klug, S | 1 |
| Merker, HJ | 1 |
| Jäckh, R | 1 |
8 other studies available for glycolic acid and Pregnancy
| Article | Year |
|---|---|
Disposition of glycolic acid into rat and rabbit embryos in vitro.
Topics: Animals; Binding, Competitive; Embryo Culture Techniques; Embryo, Mammalian; Female; Glycolates; Hyd | 2014 |
The impact of dose rate on ethylene glycol developmental toxicity and pharmacokinetics in pregnant CD rats.
Topics: Abnormalities, Multiple; Administration, Oral; Animals; Dose-Response Relationship, Drug; Drug Admin | 2011 |
Fetal cartilage engineering from amniotic mesenchymal progenitor cells.
Topics: Amniotic Fluid; Animals; Cartilage; Cell Separation; Chondrocytes; Collagen Type II; DNA; Elastin; F | 2006 |
The combination of glycolic acid and hydroquinone or kojic acid for the treatment of melasma and related conditions.
Topics: Adult; Aged; Aged, 80 and over; Drug Evaluation; Drug Therapy, Combination; Female; Glycolates; Huma | 1996 |
Ethylene glycol developmental toxicity: unraveling the roles of glycolic acid and metabolic acidosis.
Topics: Acidosis; Animals; Body Weight; Bone and Bones; Ethylene Glycol; Female; Fetus; Glycolates; Keratoly | 1999 |
Developmental toxicity study of glycolic acid in rats.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Body Weight; Bone and Bones; Dose-Respon | 1999 |
Dose-dependent nonlinear pharmacokinetics of ethylene glycol metabolites in pregnant (GD 10) and nonpregnant Sprague-Dawley rats following oral administration of ethylene glycol.
Topics: Administration, Oral; Animals; Area Under Curve; Carbon Isotopes; Dose-Response Relationship, Drug; | 2001 |
Effects of ethylene glycol and metabolites on in vitro development of rat embryos during organogenesis.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animal Testing Alternatives; Animals; Dose-Response Relat | 2001 |