glycolic acid has been researched along with Melanosis in 38 studies
glycolic acid: RN given refers to parent cpd
glycolic acid : A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
Melanosis: Disorders of increased melanin pigmentation that develop without preceding inflammatory disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study and compare the therapeutic efficacy and side effects of a 35% glycolic acid (GA) full face peel alone or in combination with a 10% or 20% trichloroacetic acid (TCA) spot peel for facial melasma." | 2.90 | Comparative Efficacy of a 35% Glycolic Acid Peel Alone or in Combination With a 10% and 20% Trichloroacetic Acid Spot Peel for Melasma: A Randomized Control Trial. ( Bhalla, M; Garg, S; Kaur, J; Kumar, A; Thami, GP, 2019) |
| "Melasma is acquired symmetric hypermelanosis characterized by light-to-deep brown pigmentation over cheeks, forehead, upper lip, and nose." | 2.82 | Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasma. ( Bansal, S; Garg, V; Gupta, C; Sarkar, R; Sethi, S, 2016) |
| " The incidence of adverse effect was maximum with GA peel followed by lactic peel and vitamin C." | 2.82 | Clinical efficacy and safety of 20% glycolic peel, 15% lactic peel, and topical 20% vitamin C in constitutional type of periorbital melanosis: a comparative study. ( Dayal, S; Jain, VK; Khetri, S; Sahu, P, 2016) |
| "Melasma is a cutaneous disorder that primarily affects females of Hispanic and Asian descent." | 2.78 | Open-label evaluation of a novel skin brightening system containing 0.01% decapeptide-12 in combination with 20% buffered glycolic acid for the treatment of mild to moderate facial melasma. ( Arroyave, G; Carvajal, AC; Echeverry, HF; Flórez, AM; Ramírez, SP; Salazar, JC, 2013) |
| "Glycolic acid 70% peel was applied on the right side, whereas nanosome vitamin C was applied by iontophoresis on the other side." | 2.77 | A single-blinded comparative study between the use of glycolic acid 70% peel and the use of topical nanosome vitamin C iontophoresis in the treatment of melasma. ( Sobhi, AM; Sobhi, RM, 2012) |
| "Melasma is a common pigmentary disorder that poses therapeutic challenges." | 2.76 | A randomized, observer-blinded, comparison of combined 1064-nm Q-switched neodymium-doped yttrium-aluminium-garnet laser plus 30% glycolic acid peel vs. laser monotherapy to treat melasma. ( Hong, CK; Kim, DH; Kim, HK; Li, K; Park, KY; Seo, SJ, 2011) |
| "Melasma is an irregular brownish pigmentation observed on the faces of young to middle-aged women, especially of Asian races, which may contribute to various emotional disturbances." | 2.76 | Comparison between 1% tretinoin peeling versus 70% glycolic acid peeling in the treatment of female patients with melasma. ( Faghihi, G; Shahingohar, A; Siadat, AH, 2011) |
| " Therefore, the present study suggests that combined treatment with serial glycolic acid peels, azelaic acid cream and adapalene gel should be considered as an effective and safe therapy in recalcitrant melasma." | 2.73 | Efficacy and safety of serial glycolic acid peels and a topical regimen in the treatment of recalcitrant melasma. ( Arca, E; Erbil, H; Kurumlu, Z; Sezer, E; Taştan, B, 2007) |
| "Glycolic acid has been added to hydroquinone formulations in the past to enhance their depigmentation effects, but may cause irritation, leading to postinflammatory hyperpigmentation." | 2.71 | Safety and efficacy of 4% hydroquinone combined with 10% glycolic acid, antioxidants, and sunscreen in the treatment of melasma. ( Guevara, IL; Pandya, AG, 2003) |
| "Melasma is difficult to clear." | 2.69 | Treatment of melasma using kojic acid in a gel containing hydroquinone and glycolic acid. ( Lim, JT, 1999) |
| "Melasma is a common disorder of facial hyperpigmentation among Asian women." | 2.68 | Glycolic acid peels in the treatment of melasma among Asian women. ( Lim, JT; Tham, SN, 1997) |
| "Melasma is an acquired challenging pigmentary skin problem, which commonly affects the face." | 1.62 | Modified Jessner's Solution Combined With Trichloroacetic Acid 20% Versus Glycolic Acid 70% Combined With Trichloroacetic Acid 20% in the Treatment of Melasma. ( Abdel Motaleb, AA; Abdel-Majid, EM; Helmy, ER, 2021) |
| "Melasma is a disfiguring dermatologic condition and its treatment is still considered a challenge." | 1.62 | Microdermabrasion assisted delivery of glycolic acid 70% peel for the treatment of melasma in dark-skinned patients. ( Abdel-Motaleb, AA; Bakr, RM, 2021) |
| "Melasma is a pigmentary disorder often recalcitrant to treatment." | 1.37 | Treatment of melasma with a depigmentation cream determined with colorimetry. ( Aydin, F; Bek, Y; Canturk, T; Ozcan, M; Ozden, MG; Sabancilar, E; Senturk, N; Turanli, AY, 2011) |
| "Melasma is an acquired hypermelanosis that is often recalcitrant to treatment with hypopigmenting agents." | 1.31 | Efficacy of glycolic acid peels in the treatment of melasma. ( Gonzales, RM; Guevara, IL; Hurley, ME; Pandya, AG, 2002) |
| "Melasma is a common disorder of facial hyperpigmentation." | 1.31 | Safety and efficacy of glycolic acid facial peel in Indian women with melasma. ( Handa, S; Javaheri, SM; Kaur, I; Kumar, B, 2001) |
| "The kojic acid preparation was more irritating." | 1.29 | The combination of glycolic acid and hydroquinone or kojic acid for the treatment of melasma and related conditions. ( Fulton, JE; Garcia, A, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (15.79) | 18.2507 |
| 2000's | 11 (28.95) | 29.6817 |
| 2010's | 16 (42.11) | 24.3611 |
| 2020's | 5 (13.16) | 2.80 |
| Authors | Studies |
|---|---|
| Zeeshan, M | 1 |
| Arfeen, N | 1 |
| Sonthalia, S | 1 |
| Singh, A | 1 |
| Roy, PK | 1 |
| Garg, S | 1 |
| Thami, GP | 1 |
| Bhalla, M | 2 |
| Kaur, J | 1 |
| Kumar, A | 1 |
| Sahu, P | 4 |
| Dayal, S | 5 |
| Abdel-Majid, EM | 1 |
| Helmy, ER | 1 |
| Abdel Motaleb, AA | 1 |
| Abdel-Motaleb, AA | 1 |
| Bakr, RM | 1 |
| Bhardwaj, N | 1 |
| Ramírez, SP | 1 |
| Carvajal, AC | 1 |
| Salazar, JC | 1 |
| Arroyave, G | 1 |
| Flórez, AM | 1 |
| Echeverry, HF | 1 |
| Chaudhary, S | 1 |
| Vachiramon, V | 1 |
| Sahawatwong, S | 1 |
| Sirithanabadeekul, P | 1 |
| Ibrahim, ZA | 1 |
| Gheida, SF | 1 |
| El Maghraby, GM | 1 |
| Farag, ZE | 1 |
| Sarkar, R | 4 |
| Garg, V | 1 |
| Bansal, S | 1 |
| Sethi, S | 1 |
| Gupta, C | 1 |
| Jain, VK | 1 |
| Khetri, S | 1 |
| Dua, R | 1 |
| Rendon, M | 1 |
| Cardona, LM | 1 |
| Bussear, EW | 1 |
| Benitez, AL | 1 |
| Colón, LE | 1 |
| Johnson, LA | 1 |
| Ilknur, T | 1 |
| Biçak, MU | 1 |
| Demirtaşoğlu, M | 1 |
| Ozkan, S | 1 |
| Guevara, IL | 3 |
| Werlinger, KD | 1 |
| Pandya, AG | 4 |
| Godse, KV | 1 |
| Sakhia, J | 1 |
| Sabancilar, E | 1 |
| Aydin, F | 1 |
| Bek, Y | 1 |
| Ozden, MG | 1 |
| Ozcan, M | 1 |
| Senturk, N | 1 |
| Canturk, T | 1 |
| Turanli, AY | 1 |
| Sheth, VM | 1 |
| Park, KY | 1 |
| Kim, DH | 1 |
| Kim, HK | 1 |
| Li, K | 1 |
| Seo, SJ | 1 |
| Hong, CK | 1 |
| Faghihi, G | 1 |
| Shahingohar, A | 1 |
| Siadat, AH | 1 |
| Sobhi, RM | 1 |
| Sobhi, AM | 1 |
| Kaur, C | 1 |
| Kanwar, AJ | 1 |
| Hurley, ME | 1 |
| Gonzales, RM | 1 |
| Coleman, WP | 1 |
| Brody, HJ | 2 |
| Sehgal, VN | 1 |
| Luthra, A | 1 |
| Aggarwal, AK | 1 |
| Khunger, N | 1 |
| Jain, RK | 1 |
| Kligman, DE | 1 |
| Erbil, H | 1 |
| Sezer, E | 1 |
| Taştan, B | 1 |
| Arca, E | 1 |
| Kurumlu, Z | 1 |
| Garg, VK | 1 |
| Agarwal, R | 1 |
| Clark, CP | 1 |
| Garcia, A | 1 |
| Fulton, JE | 1 |
| Lawrence, N | 1 |
| Cox, SE | 1 |
| Lim, JT | 2 |
| Tham, SN | 1 |
| Cotellessa, C | 1 |
| Peris, K | 1 |
| Onorati, MT | 1 |
| Fargnoli, MC | 1 |
| Chimenti, S | 1 |
| Javaheri, SM | 1 |
| Handa, S | 1 |
| Kaur, I | 1 |
| Kumar, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Combined Trichlotoaceticacid and Microneedle Versus Trichlroacetic Acid Alone in the Treatment of Melasma[NCT03472235] | 40 participants (Anticipated) | Interventional | 2018-04-05 | Not yet recruiting | |||
| Different Dermatological Approaches in Treatment of Melasma: A Split Face Randomized Clinical Trial[NCT03923062] | Phase 4 | 40 participants (Anticipated) | Interventional | 2020-02-01 | Not yet recruiting | ||
| THE METFORMIN AND TRICHLOROACETIC ACID IN TREATMENT OF MELASMA[NCT03475524] | Phase 4 | 60 participants (Anticipated) | Interventional | 2019-04-01 | Recruiting | ||
| Comparing the Efficacy and Safety of Combined Glycolic Acid and Salicylic Acid Peel Versus Glycolic Acid Peel Alone in the Treatment of Melasma: A Split Face Study[NCT02812719] | Early Phase 1 | 0 participants (Actual) | Interventional | 2018-07-31 | Withdrawn (stopped due to Study did not receive funding and will not be implemented.) | ||
| The Efficacy of Combined Peels in Treatment of Melasma Using Modified Jessner's Solution With 20%Trichloroacetic Acid Versus 70%Glycolic Acid With 20% Trichloroacetic Acid : A Split-face Study[NCT03153852] | Phase 4 | 30 participants (Anticipated) | Interventional | 2018-03-15 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for glycolic acid and Melanosis
| Article | Year |
|---|---|
Melasma: a comprehensive update: part II.
Topics: Administration, Topical; Asian People; Chemexfoliation; Dicarboxylic Acids; Drug Therapy, Combinatio | 2011 |
Melasma: a comprehensive update: part II.
Topics: Administration, Topical; Asian People; Chemexfoliation; Dicarboxylic Acids; Drug Therapy, Combinatio | 2011 |
Melasma: a comprehensive update: part II.
Topics: Administration, Topical; Asian People; Chemexfoliation; Dicarboxylic Acids; Drug Therapy, Combinatio | 2011 |
Melasma: a comprehensive update: part II.
Topics: Administration, Topical; Asian People; Chemexfoliation; Dicarboxylic Acids; Drug Therapy, Combinatio | 2011 |
Melasma: a comprehensive update: part II.
Topics: Administration, Topical; Asian People; Chemexfoliation; Dicarboxylic Acids; Drug Therapy, Combinatio | 2011 |
Melasma: a comprehensive update: part II.
Topics: Administration, Topical; Asian People; Chemexfoliation; Dicarboxylic Acids; Drug Therapy, Combinatio | 2011 |
Melasma: a comprehensive update: part II.
Topics: Administration, Topical; Asian People; Chemexfoliation; Dicarboxylic Acids; Drug Therapy, Combinatio | 2011 |
Melasma: a comprehensive update: part II.
Topics: Administration, Topical; Asian People; Chemexfoliation; Dicarboxylic Acids; Drug Therapy, Combinatio | 2011 |
Melasma: a comprehensive update: part II.
Topics: Administration, Topical; Asian People; Chemexfoliation; Dicarboxylic Acids; Drug Therapy, Combinatio | 2011 |
Alpha hydroxy acids in skin care.
Topics: Acne Vulgaris; Chemexfoliation; Female; Glycolates; Humans; Hydroxy Acids; Male; Melanosis; Skin Agi | 1996 |
21 trials available for glycolic acid and Melanosis
| Article | Year |
|---|---|
Comparative Efficacy of a 35% Glycolic Acid Peel Alone or in Combination With a 10% and 20% Trichloroacetic Acid Spot Peel for Melasma: A Randomized Control Trial.
Topics: Adult; Chemexfoliation; Combined Modality Therapy; Face; Female; Glycolates; Humans; Keratolytic Age | 2019 |
Open-label evaluation of a novel skin brightening system containing 0.01% decapeptide-12 in combination with 20% buffered glycolic acid for the treatment of mild to moderate facial melasma.
Topics: Administration, Cutaneous; Adult; Antioxidants; Dermatologic Agents; Drug Therapy, Combination; Face | 2013 |
Efficacy of combination of glycolic acid peeling with topical regimen in treatment of melasma.
Topics: Adult; Anti-Inflammatory Agents; Antioxidants; Chemexfoliation; Female; Glycolates; Humans; Hydrocor | 2013 |
Treatment of melasma in men with low-fluence Q-switched neodymium-doped yttrium-aluminum-garnet laser versus combined laser and glycolic acid peeling.
Topics: Administration, Cutaneous; Adult; Aged; Combined Modality Therapy; Follow-Up Studies; Glycolates; Hu | 2015 |
Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasma.
Topics: Adult; Antioxidants; Chemexfoliation; Drug Combinations; Female; Follow-Up Studies; Glycolates; Huma | 2016 |
Clinical efficacy and safety of 20% glycolic peel, 15% lactic peel, and topical 20% vitamin C in constitutional type of periorbital melanosis: a comparative study.
Topics: Administration, Cutaneous; Adult; Antioxidants; Ascorbic Acid; Chemexfoliation; Eye; Facial Dermatos | 2016 |
Combination of glycolic acid peel and topical 20% azelaic acid cream in melasma patients: efficacy and improvement in quality of life.
Topics: Administration, Cutaneous; Adult; Chemexfoliation; Combined Modality Therapy; Dermatologic Agents; D | 2017 |
Successful treatment of moderate to severe melasma with triple-combination cream and glycolic acid peels: a pilot study.
Topics: Administration, Cutaneous; Adult; Chemexfoliation; Dermatologic Agents; Drug Combinations; Drug Ther | 2008 |
Glycolic acid peels versus amino fruit acid peels in the treatment of melasma.
Topics: Administration, Cutaneous; Adult; Amino Acids; Chemexfoliation; Follow-Up Studies; Fruit; Glycolates | 2010 |
A randomized, observer-blinded, comparison of combined 1064-nm Q-switched neodymium-doped yttrium-aluminium-garnet laser plus 30% glycolic acid peel vs. laser monotherapy to treat melasma.
Topics: Adult; Combined Modality Therapy; Female; Glycolates; Humans; Keratolytic Agents; Korea; Lasers, Sol | 2011 |
Comparison between 1% tretinoin peeling versus 70% glycolic acid peeling in the treatment of female patients with melasma.
Topics: Adult; Double-Blind Method; Facial Dermatoses; Female; Glycolates; Humans; Keratolytic Agents; Melan | 2011 |
A single-blinded comparative study between the use of glycolic acid 70% peel and the use of topical nanosome vitamin C iontophoresis in the treatment of melasma.
Topics: Adult; Antioxidants; Ascorbic Acid; Chemexfoliation; Female; Glycolates; Humans; Iontophoresis; Kera | 2012 |
The combination of glycolic acid peels with a topical regimen in the treatment of melasma in dark-skinned patients: a comparative study.
Topics: Administration, Topical; Adult; Chemexfoliation; Drug Combinations; Female; Glycolates; Humans; Hydr | 2002 |
Safety and efficacy of 4% hydroquinone combined with 10% glycolic acid, antioxidants, and sunscreen in the treatment of melasma.
Topics: Administration, Cutaneous; Adult; Ascorbic Acid; Drug Therapy, Combination; Female; Glycolates; Huma | 2003 |
Evaluation of graded strength glycolic acid (GA) facial peel: an Indian experience.
Topics: Adolescent; Adult; Chemexfoliation; Cohort Studies; Dose-Response Relationship, Drug; Esthetics; Eva | 2003 |
Efficacy and safety of serial glycolic acid peels and a topical regimen in the treatment of recalcitrant melasma.
Topics: Adapalene; Administration, Topical; Adult; Chemexfoliation; Dermatologic Agents; Dicarboxylic Acids; | 2007 |
Comparative evaluation of beneficiary effects of priming agents (2% hydroquinone and 0.025% retinoic acid) in the treatment of melasma with glycolic acid peels.
Topics: Adolescent; Adult; Chemexfoliation; Female; Glycolates; Humans; Hydroquinones; Male; Melanosis; Midd | 2008 |
Treatment of melasma with Jessner's solution versus glycolic acid: a comparison of clinical efficacy and evaluation of the predictive ability of Wood's light examination.
Topics: Chemexfoliation; Colorimetry; Drug Combinations; Ethanol; Facial Dermatoses; Female; Glycolates; Hum | 1997 |
Glycolic acid peels in the treatment of melasma among Asian women.
Topics: Administration, Topical; Adult; Asian People; Chemexfoliation; China; Drug Combinations; Female; Gly | 1997 |
Treatment of melasma using kojic acid in a gel containing hydroquinone and glycolic acid.
Topics: Adult; Aspergillus oryzae; Double-Blind Method; Drug Combinations; Facial Dermatoses; Female; Gels; | 1999 |
The use of chemical peelings in the treatment of different cutaneous hyperpigmentations.
Topics: Adult; Caustics; Chemexfoliation; Facial Dermatoses; Female; Glycolates; Humans; Keratolytic Agents; | 1999 |
15 other studies available for glycolic acid and Melanosis
| Article | Year |
|---|---|
Treatment of acanthosis nigricans with sequential salicylic acid-mandelic acid combination peel and maintenance with glycolic acid-urea combination cream: A retrospective pilot study.
Topics: Acanthosis Nigricans; Chemexfoliation; Glycolates; Humans; Keratolytic Agents; Mandelic Acids; Melan | 2022 |
Most worthwhile superficial chemical peel for melasma of skin of color: Authors' experience of glycolic, trichloroacetic acid, and lactic peel.
Topics: Chemexfoliation; Glycolates; Humans; Keratolytic Agents; Melanosis; Quality of Life; Skin Pigmentati | 2021 |
Modified Jessner's Solution Combined With Trichloroacetic Acid 20% Versus Glycolic Acid 70% Combined With Trichloroacetic Acid 20% in the Treatment of Melasma.
Topics: Adult; Chemexfoliation; Drug Combinations; Drug Therapy, Combination; Ethanol; Female; Glycolates; H | 2021 |
Microdermabrasion assisted delivery of glycolic acid 70% peel for the treatment of melasma in dark-skinned patients.
Topics: Chemexfoliation; Female; Glycolates; Humans; Melanosis; Treatment Outcome | 2021 |
Topical 5% tranexamic acid with 30% glycolic acid peel: An useful combination for accelerating the improvement in melasma.
Topics: Chemexfoliation; Glycolates; Humans; Melanosis; Quality of Life; Tranexamic Acid; Treatment Outcome | 2021 |
Evaluation of the efficacy and safety of combinations of hydroquinone, glycolic acid, and hyaluronic acid in the treatment of melasma.
Topics: Dermatologic Agents; Dermoscopy; Female; Glycolates; Humans; Hyaluronic Acid; Hydroquinones; Melanos | 2015 |
Tolerability and efficacy of a novel formulation in the treatment of melasma.
Topics: Adult; Dermatologic Agents; Drug Therapy, Combination; Female; Glycolates; Humans; Hyaluronic Acid; | 2010 |
Triple combination and glycolic acid peels in melasma in Indian patients.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Antioxidants; Chemexfoliation; Drug Combin | 2011 |
Treatment of melasma with a depigmentation cream determined with colorimetry.
Topics: Adult; Colorimetry; Drug Combinations; Female; Glycolates; Humans; Male; Melanosis; Middle Aged; Phy | 2011 |
Efficacy of glycolic acid peels in the treatment of melasma.
Topics: Adolescent; Adult; Aged; Chemexfoliation; Esthetics; Facial Dermatoses; Female; Follow-Up Studies; G | 2002 |
Efficacy of low-strength glycolic acid application in the treatment of melasma.
Topics: Dose-Response Relationship, Drug; Glycolates; Humans; Keratolytic Agents; Melanosis | 2003 |
Tretinoin peels versus glycolic acid peels in the treatment of Melasma in dark-skinned patients.
Topics: Administration, Topical; Adult; Asian People; Chemexfoliation; Face; Female; Glycolates; Humans; Ind | 2004 |
Tretinoin peels versus glycolic acid peels.
Topics: Clinical Trials as Topic; Confounding Factors, Epidemiologic; Drug Administration Schedule; Glycolat | 2004 |
The combination of glycolic acid and hydroquinone or kojic acid for the treatment of melasma and related conditions.
Topics: Adult; Aged; Aged, 80 and over; Drug Evaluation; Drug Therapy, Combination; Female; Glycolates; Huma | 1996 |
Safety and efficacy of glycolic acid facial peel in Indian women with melasma.
Topics: Adult; Chemexfoliation; Face; Female; Glycolates; Humans; India; Keratolytic Agents; Melanosis; Midd | 2001 |