glycolic acid has been researched along with Kidney Diseases in 4 studies
glycolic acid: RN given refers to parent cpd
glycolic acid : A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ethylene glycol poisoning causes metabolic acidosis and renal failure and may cause death." | 9.09 | Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group. ( Brent, J; Burkhart, KK; Donovan, JW; Kulig, K; McMartin, K; Phillips, S; Wells, M, 1999) |
| "Ethylene glycol poisoning causes metabolic acidosis and renal failure and may cause death." | 5.09 | Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group. ( Brent, J; Burkhart, KK; Donovan, JW; Kulig, K; McMartin, K; Phillips, S; Wells, M, 1999) |
| "Ethylene glycol poisoning is a medical emergency that presents challenges for clinicians and clinical laboratories." | 1.39 | The 'gap' in the 'plasma osmolar gap'. ( Arora, A, 2013) |
| " The development and evaluation of the PBPK model was based upon previously published pharmacokinetic studies coupled with measured blood and tissue partition coefficients and rates of in vitro metabolism of glyoxylic acid to oxalic acid, glycine and other metabolites using primary hepatocytes isolated from male Wistar rats and humans." | 1.37 | Extension of a PBPK model for ethylene glycol and glycolic acid to include the competitive formation and clearance of metabolites associated with kidney toxicity in rats and humans. ( Bartels, MJ; Corley, RA; Creim, J; Hansen, SC; McMartin, KE; Saghir, SA; Snellings, WM, 2011) |
| "Ethylene glycol was mixed in the diet at concentrations to deliver constant target dosage levels of 0, 50, 150, 500, or 1000 mg/kg/day for 16 weeks to groups of 10 male Wistar and 10 male F-344 rats based on weekly group mean body weights and feed consumption." | 1.32 | Subchronic toxicity of ethylene glycol in Wistar and F-344 rats related to metabolism and clearance of metabolites. ( Corley, RA; Cruzan, G; Deyo, JA; Gingell, R; Hard, GC; McMartin, KE; Mertens, JJ; Snellings, WM, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arora, A | 1 |
| Corley, RA | 2 |
| Saghir, SA | 1 |
| Bartels, MJ | 1 |
| Hansen, SC | 1 |
| Creim, J | 1 |
| McMartin, KE | 2 |
| Snellings, WM | 2 |
| Cruzan, G | 1 |
| Hard, GC | 1 |
| Mertens, JJ | 1 |
| Gingell, R | 1 |
| Deyo, JA | 1 |
| Brent, J | 1 |
| McMartin, K | 1 |
| Phillips, S | 1 |
| Burkhart, KK | 1 |
| Donovan, JW | 1 |
| Wells, M | 1 |
| Kulig, K | 1 |
1 trial available for glycolic acid and Kidney Diseases
| Article | Year |
|---|---|
Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group.
Topics: Adult; Aged; Antidotes; Ethylene Glycol; Female; Fomepizole; Glycolates; Humans; Keratolytic Agents; | 1999 |
3 other studies available for glycolic acid and Kidney Diseases
| Article | Year |
|---|---|
The 'gap' in the 'plasma osmolar gap'.
Topics: Acidosis; Adult; Alcohol Dehydrogenase; Alcohols; Biomarkers; Ethylene Glycol; Glycolates; Humans; K | 2013 |
Extension of a PBPK model for ethylene glycol and glycolic acid to include the competitive formation and clearance of metabolites associated with kidney toxicity in rats and humans.
Topics: Animals; Calcium Oxalate; Dose-Response Relationship, Drug; Drug Administration Routes; Ethylene Gly | 2011 |
Subchronic toxicity of ethylene glycol in Wistar and F-344 rats related to metabolism and clearance of metabolites.
Topics: Animals; Biotransformation; Body Weight; Diet; Drinking; Ethylene Glycol; Glycolates; Kidney; Kidney | 2004 |