Page last updated: 2024-10-18

glycolic acid and Acidosis

glycolic acid has been researched along with Acidosis in 8 studies

glycolic acid: RN given refers to parent cpd
glycolic acid : A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.

Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.

Research Excerpts

ExcerptRelevanceReference
" A suggested mechanism for this toxicity is that the EG metabolite, glycolic acid (GA), causes acidosis which may affect the embryonic heart rate (HR)."7.88Editor's Highlight: Ethylene Glycol Teratogenicity: A Role for Embryonic Acidosis? ( Moore, NP; Ritchie, HE; Webster, WS, 2018)
"This study sought to determine the relative roles of glycolic acid (GA), a toxicologically important metabolite of ethylene glycol (EG), and metabolic acidosis in causing developmental toxicity in Sprague-Dawley rats."7.70Ethylene glycol developmental toxicity: unraveling the roles of glycolic acid and metabolic acidosis. ( Carney, EW; Dittenber, DA; Dryzga, MD; Freshour, NL, 1999)
" A suggested mechanism for this toxicity is that the EG metabolite, glycolic acid (GA), causes acidosis which may affect the embryonic heart rate (HR)."3.88Editor's Highlight: Ethylene Glycol Teratogenicity: A Role for Embryonic Acidosis? ( Moore, NP; Ritchie, HE; Webster, WS, 2018)
"This study sought to determine the relative roles of glycolic acid (GA), a toxicologically important metabolite of ethylene glycol (EG), and metabolic acidosis in causing developmental toxicity in Sprague-Dawley rats."3.70Ethylene glycol developmental toxicity: unraveling the roles of glycolic acid and metabolic acidosis. ( Carney, EW; Dittenber, DA; Dryzga, MD; Freshour, NL, 1999)
"Ethylene glycol intoxication produces a severe metabolic acidosis with an increased anion gap."3.67Organic acids in ethylene glycol intoxication. ( Clay, K; Gabow, PA; Lepoff, R; Sullivan, JB, 1986)
"Ethylene glycol poisoning is a medical emergency that presents challenges for clinicians and clinical laboratories."1.39The 'gap' in the 'plasma osmolar gap'. ( Arora, A, 2013)
"Ethylene glycol ingestion was subsequently diagnosed."1.34Falsely elevated point-of-care lactate measurement after ingestion of ethylene glycol. ( Brindley, DN; Brindley, PG; Butler, MS; Cembrowski, G, 2007)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ritchie, HE1
Moore, NP1
Webster, WS1
Arora, A1
Hložek, T1
Bursová, M1
Coufal, P1
Čabala, R1
Brindley, PG1
Butler, MS1
Cembrowski, G1
Brindley, DN1
Jorens, PG1
Fraser, AD1
Carney, EW1
Freshour, NL1
Dittenber, DA1
Dryzga, MD1
Gabow, PA1
Clay, K1
Sullivan, JB1
Lepoff, R1

Other Studies

8 other studies available for glycolic acid and Acidosis

ArticleYear
Editor's Highlight: Ethylene Glycol Teratogenicity: A Role for Embryonic Acidosis?
    Toxicological sciences : an official journal of the Society of Toxicology, 2018, 02-01, Volume: 161, Issue:2

    Topics: Acidosis; Animals; Culture Media; Embryonic Development; Ethylene Glycol; Gestational Age; Glycolate

2018
The 'gap' in the 'plasma osmolar gap'.
    BMJ case reports, 2013, Aug-08, Volume: 2013

    Topics: Acidosis; Adult; Alcohol Dehydrogenase; Alcohols; Biomarkers; Ethylene Glycol; Glycolates; Humans; K

2013
Identification and quantification of acidosis inducing metabolites in cases of alcohols intoxication by GC-MS for emergency toxicology.
    Journal of pharmaceutical and biomedical analysis, 2015, Oct-10, Volume: 114

    Topics: Acetates; Acidosis; Alcoholic Intoxication; Blood Chemical Analysis; Calibration; Chemistry Techniqu

2015
Falsely elevated point-of-care lactate measurement after ingestion of ethylene glycol.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2007, Apr-10, Volume: 176, Issue:8

    Topics: Acidosis; Ethylene Glycol; False Negative Reactions; Female; Glycolates; Glyoxylates; Humans; Kerato

2007
Accuracy of point-of-care measurements.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2007, Oct-23, Volume: 177, Issue:9

    Topics: Acidosis; Ethylene Glycol; False Negative Reactions; Female; Glycolates; Glyoxylates; Humans; Kerato

2007
Ethylene glycol, glycolic acid, and metabolic acidosis of unknown origin.
    Clinical chemistry, 1993, Volume: 39, Issue:8

    Topics: Acidosis; Diagnosis, Differential; Ethylene Glycol; Ethylene Glycols; Glycolates; Humans; Infant; Me

1993
Ethylene glycol developmental toxicity: unraveling the roles of glycolic acid and metabolic acidosis.
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 50, Issue:1

    Topics: Acidosis; Animals; Body Weight; Bone and Bones; Ethylene Glycol; Female; Fetus; Glycolates; Keratoly

1999
Organic acids in ethylene glycol intoxication.
    Annals of internal medicine, 1986, Volume: 105, Issue:1

    Topics: Acidosis; Acute Kidney Injury; Adult; Carboxylic Acids; Ethanol; Ethylene Glycol; Ethylene Glycols;

1986