glycogen and Urinary-Retention

glycogen has been researched along with Urinary-Retention* in 1 studies

Other Studies

1 other study(ies) available for glycogen and Urinary-Retention

ArticleYear
Structural assessment of the urethral sphincter in women with urinary retention.
    The Journal of urology, 2005, Volume: 173, Issue:4

    The pathophysiology of urinary retention in women is generally unknown but a subgroup of women with urinary retention have been diagnosed as having so-called primary disorder of sphincter relaxation on the basis of an abnormal urethral sphincter electromyogram. It was suggested this sphincter overactivity could lead to work hypertrophy of the urethral rhabdosphincter and in this study we looked for any evidence of such muscle fiber hypertrophy.. In 9 women 18 to 45 years old (mean age 31.6) with urinary retention and overactive urethral sphincter electromyogram, light and electron microscopy were used to examine core needle biopsies of the urethral rhabdosphincter taken under transvaginal ultrasound control. Of the 9 patients only 5 biopsies processed for light microscopy and 4 processed for electron microscopy contained striated urethral muscle fibers. The results of these biopsies were compared to the morphology of a control specimen from a postmenopausal woman without a history of urinary retention.. On light microscopy the urethral rhabdosphincter fiber diameter did not differ among patients (mean average 7.6 mum), was less than that reported in the literature (15 to 20), but did not differ from that of the control (mean 9.9). In all patients electron microscopy showed excessive peripheral sarcoplasm with lipid and glycogen deposition, and sarcoplasmic accumulation of normal mitochondria. These ultrastructural abnormalities were not seen in the control.. To our knowledge this is the first morphological description of the urethral rhabdosphincter in a subgroup of women with urinary retention. Mean rhabdosphincter fiber diameter was approximately the same in patients and controls. This study does not support the previous theory that urethral sphincter overactivity in a subgroup of women with urinary retention leads to work hyperplasia of urethral rhabdosphincter fibers. An alternative hypothesis is suggested.

    Topics: Adolescent; Adult; Biopsy, Needle; Electromyography; Female; Glycogen; Humans; Hypertrophy; Lipids; Microscopy, Electron; Middle Aged; Mitochondria, Muscle; Muscle Fibers, Skeletal; Muscle Fibers, Slow-Twitch; Sarcoplasmic Reticulum; Ultrasonography, Interventional; Urethra; Urinary Retention

2005