glycogen and Peritoneal-Neoplasms

Topics: Aged; Carcinoid Tumor; Carcinoma; Colonic Polyps; Colonoscopy; Diagnosis, Differential; Gastrointestinal Hemorrhage; Gene Deletion; Genes, p16; Glycogen; Humans; Intestinal Neoplasms; Intestine, Small; Lung Neoplasms; Male; Mesothelioma; Mesothelioma, Malignant; Neoplasm Invasiveness; Peritoneal Neoplasms; Prognosis

A clear cell mesothelioma presenting as an incarcerated ventral abdominal hernia in a 67-year-old man who had no history of asbestos exposure is described. The cause of the cytoplasmic clearing was the presence of large amounts of glycogen. Although uncommon, this variant of mesothelioma is important to recognize because it can be easily confused with other clear cell tumors involving the serosal membranes. Significant recent advances in the immunohistochemistry of epithelioid mesothelioma are briefly reviewed because immunohistochemical studies can be helpful in establishing the correct diagnosis.

Topics: Aged; Biomarkers, Tumor; Diagnosis, Differential; Glycogen; Hernia, Abdominal; Humans; Immunoenzyme Techniques; Male; Mesothelioma; Peritoneal Neoplasms

Micropapillary variant of transitional cell carcinoma (TCC) is a rare entity, having a distinct micropapillary component mimicking papillary serous carcinoma of the ovary and has been reported exclusively in the urinary bladder. We experienced a case of micropapillary variant of TCC in the ureter. The tumor showed a predominant proportion of micropapillary component and accompanied a TCC in situ lesion and a high-grade TCC. A metastatic lesion in the regional lymph node also showed an entirely micropapillary pattern. Initially, our case was confused with adenocarcinoma, especially metastatic, because the micropapillary architecture resembled an abortive glandular structure and tumor cell nests were predominantly located in empty spaces mimicking vascular invasion. The patient died with peritoneal metastases 20 months after the initial diagnosis. We report the first case of a micropapillary variant of TCC occurring in the ureter.

Topics: Aged; Carcinoma in Situ; Carcinoma, Papillary; Carcinoma, Transitional Cell; Cytoplasm; Desmosomes; Diagnosis, Differential; Fatal Outcome; Glycogen; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Peritoneal Neoplasms; Ureteral Neoplasms

Topics: Biopsy; Bronchial Neoplasms; Cell Membrane; Cytoplasm; Cytoplasmic Granules; Endoplasmic Reticulum; Glycogen; Humans; Inclusion Bodies; Lipids; Male; Mesothelioma; Microscopy, Electron; Neoplasm Metastasis; Peritoneal Neoplasms; Pleural Neoplasms

Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Fractionation; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Enzyme Activation; Glucose; Glucosephosphates; Glucosyltransferases; Glycogen; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Liver; Liver Neoplasms; Maleates; Microsomes; Muscles; Neoplasms, Experimental; Nucleoside Diphosphate Sugars; Organ Specificity; Peritoneal Neoplasms; Rats; Tromethamine

Topics: Adenocarcinoma; Adenoma, Islet Cell; Bile Duct Neoplasms; Biological Assay; Black People; Carbohydrate Metabolism; Carboxy-Lyases; Glucose; Glycogen; Hypoglycemia; Insulin; Neoplasms; Pancreatic Neoplasms; Paraganglioma; Pelvic Neoplasms; Peritoneal Neoplasms; Rats; Research; Sodium Chloride; Stomach Neoplasms