glycogen has been researched along with Otosclerosis* in 2 studies
2 other study(ies) available for glycogen and Otosclerosis
| Article | Year |
|---|---|
[Active otosclerosis of the stapes footplate: histological and clinical aspects of its influence on the perilymph (author's transl)].
Pathologic capillaries are usually seen in the center of an otospongious process. Next to obliteration, dilatation and increased permeability a loss of basement membrane structure is evident. Around the capillaries exists a wide network of mesenchymal cells which have a glycogen like mass within the cytoplasm; glycogen can be delivered into the extracellular fluidspace. Free erythrocytes are located around many vessels. Near the margin of the lacunae decalcificated areas are seen; in the center of these areas osteocytes undergo lysis; they show intracytoplasmatic deposits of apatite which we assume to be located within the mitochondria. The collagen structure in the neighbourhood of the osteocytes seems to be damaged. Once the resorptive process has reached the perilymphatic surface of the footplate there comes to an connection between the otospongiotic lacunae and the vestibule. Free erythrocytes, glycogen like drops and lysosomes are delivered into the perilymph. Comparing the histological results with the operative results in patients with floride otosclerosis we conclude that operation should be done as early as possible to prevent damage from the inner ear, caused by the continuous intoxication of the perilymph from the otosclerotic focus. Topics: Bone Resorption; Calcium; Capillaries; Collagen; Ear Ossicles; Extracellular Space; Glycogen; Humans; Labyrinthine Fluids; Otosclerosis; Perilymph; Stapes | 1977 |
[Vascular degeneration in otosclerosis and its influence on the mesenchymal reaction of the mucoperiost].
38 samples of middle ear mucosa were taken from different patients during stapes surgery in otosclerosis. The samples were studied light-and electronmicroscopically without decalcification. Considerable pathologic changes in the organisation of the capillaries (endothelial hydrops, proliferation of the intima and of the adventitia, total obliteration o the vessels) cause pathologic reactions on the mesenchymal elements of the submucosa. Next to fibrolysis or hyalinosis of the collagen fibers the fibrocyts show features of undergoing lysis. Free and cellular bound calcium deposits are located in these lytic areas. The epithelial lining also shows unusual inclusions as glycogen and acid mucopolysaccharides and an alterated basement membrane. We belive that the changes of the connective tissue and of the epithelium are secundary to the capillary obstruction. Topics: Apatites; Basement Membrane; Blood Vessels; Capillaries; Connective Tissue; Ear; Ear Ossicles; Ear, Middle; Glycogen; Glycosaminoglycans; Humans; Hypoxia; Mucous Membrane; Otosclerosis; Periosteum | 1975 |