glycogen and Keratitis

Electron microscopy performed in a young girl suffering from keratitis, ichthyosis, and deafness syndrome showed pathologic storage of glycogen in various types of tissues. This finding may be interpreted as evidence of an underlying inborn error of metabolism.

Topics: Child; Cytoplasm; Deafness; Female; Glycogen; Humans; Ichthyosis; Keratitis; Mitochondria; Skin; Staining and Labeling; Syndrome

Acute exposure to ultraviolet light to 257 nm wavelength produced a photokeratitis associated with characteristic metabolic alterations of corneal epithelial metabolism in rabbits. Significant increases in corneal hydration occurred simultaneously with decreased corneal epithelial glycogen content, but adenosine triphosphate content and enzyme activity of epithelial extracts were not affected despite clinical and histological damage to the corneal epithelium. The pattern and time course of ultraviolet damage to the cornea are distinctly different from those of other forms of trauma.

Topics: Animals; Body Water; Cornea; Epithelium; Glycogen; Keratitis; Metabolism; Rabbits; Ultraviolet Rays

Topics: Adult; Child; Cornea; Corneal Dystrophies, Hereditary; Cysts; Diagnosis, Differential; Epithelium; Eye Diseases; Fluorescein Angiography; Fundus Oculi; Glycogen; Humans; Keratitis; Keratitis, Dendritic; Male; Middle Aged; Ophthalmoscopy; Visual Acuity

Topics: Albumins; Animals; Cornea; Fibroblasts; Glycogen; Inflammation; Keratitis; Leukocytes; Photomicrography; Rabbits

Topics: Animals; Aspergillosis; Dexamethasone; Diabetes Mellitus, Experimental; Glycogen; Hyperglycemia; Keratitis; Rabbits