glycogen and Hypocalcemia

Topics: Animals; Calcium; Cats; Cattle; Dogs; Epithelial Cells; Extracellular Space; Glycogen; Golgi Apparatus; Hypercalcemia; Hyperplasia; Hypocalcemia; Microscopy, Electron; Microscopy, Electron, Scanning; Organoids; Parathyroid Glands; Parathyroid Hormone

We studied the effects of Russian preparation of porcine calcitonin (Calcitrinum, 1 U/100 g) on the level of glucose and total calcium, glycogen concentration in the liver, and glucose consumption by the muscle and adipose tissues in vivo and in vitro. The basal level of insulin and secretion of insulin in the dynamics of glucose tolerance test were studied after treatment with calcitonin. In addition to hypocalcemic effect, this substance produced significant hyperglycemic effects, decreased glycogen amount in the liver, inhibited insulin-induced glucose consumption by muscular and adipose tissues in vivo and in vitro, slowed down insulin secretion during glucose load, and impaired glucose tolerance. Thus, calcitonin had contra-insular effects on glucose metabolism.

Topics: Adipose Tissue; Animals; Blood Glucose; Bone Density Conservation Agents; Calcitonin; Calcium; Glucose; Glucose Tolerance Test; Glycogen; Glycogenolysis; Hyperglycemia; Hypocalcemia; Insulin; Insulin Secretion; Liver; Male; Muscles; Rats; Rats, Wistar

Topics: Animals; Cardiac Glycosides; Catecholamines; Glucagon; Glucose; Glycogen; Glycolysis; Guinea Pigs; Heart; Histamine; Humans; Hypercalcemia; Hypocalcemia; Hypoxia; Insulin; Lipid Metabolism; Musculoskeletal System; Myocarditis; Myocardium; Rabbits; Rats; Thyroxine

Topics: Animals; Blood Glucose; Blood Proteins; Dogs; Electrolytes; Glycogen; Hypocalcemia; Lipids; Male; Osmolar Concentration; Parathyroid Glands; Phosphorus; Tetany; Thyroidectomy