glycogen and Fractures--Bone

Topics: Adaptation, Physiological; Burns; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Enteral Nutrition; Fats; Fractures, Bone; Glycogen; Humans; Metabolic Clearance Rate; Nutrition Disorders; Nutritional Physiological Phenomena; Parenteral Nutrition; Parenteral Nutrition, Total; Peritonitis; Postoperative Care; Postoperative Complications; Proteins

The content of glycogen and lipids in the liver, relative liver weight, the volume of hepatocytes and their nuclei, nucleocytoplasmic index, content binucleated hepatocytes, the chemical composition of the bones of the injured limb segment was studied after 3, 7, 28 days after the fracture of the leg bone after fracture leg bone with background carbon tetrachloride intoxication in mice CBA (n = 134). After the fracture revealed functional changes in the liver at all stages of the experiment. The decrease in the liver glycogen content and lipids in the bone of the injured limb segment--collagen and phosphate--was found after fracture leg bone of against the background liver failure. Found that during the recovery period after leg bone fracture liver condition affects mineral and organic composition of the bone injured limb segment.

Topics: Animals; Carbon Tetrachloride Poisoning; Collagen; Fractures, Bone; Glycogen; Hindlimb; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred CBA; Phosphates

Differentiation and calcification of cartilage of a fracture callus morphologically, ultrastructurally, and histochemically resembles cartilage of growing epiphyseal plate. The fracture callus includes the various cartilage cell types found in the epiphyseal plate. Proliferating and hypertrophic cartilage had higher activities of cytochrome oxidase, alkaline phosphatase and glutamate aspartate transaminase than fibrocartilage. Enzymes controlling glycogen synthesis and glycolysis had higher levels of activity in fibrocartilage than in hypertrophic cartilage. Lysosomal enzymes, catalase, 6-phospho-gluconic acid and glucose 6-phosphate dehydrogenase were uniformly distributed. Alkaline phosphatase was associated with extracellular vesicles found in hypertrophic cartilage. EM dense granules were found in mitochondria in hypertrophic cartilage. There was an increase of total lipids in hypertropic and calcified cartilage as compared to resting cartilage.

Topics: Alcian Blue; Alkaline Phosphatase; Animals; Bony Callus; Calcinosis; Cartilage, Articular; Cell Differentiation; Cell Division; Citrate (si)-Synthase; Electron Transport Complex IV; Fractures, Bone; Glycogen; Glycogen Synthase; Male; Microscopy, Electron; Nucleotidyltransferases; Periodic Acid; Phosphofructokinase-1; Rabbits; Schiff Bases; Staining and Labeling

Topics: Animals; Bone and Bones; Fractures, Bone; Glycogen; Glycosaminoglycans; Histocytochemistry; Methods; Osteogenesis; Proteins; Rabbits; Wound Healing

Topics: Animals; Autoradiography; Collagen; DNA; Fracture Fixation; Fractures, Bone; Glycogen; Glycosaminoglycans; Rats

Topics: Alkaline Phosphatase; Animals; Fractures, Bone; Glycogen; Rabbits; Tibial Fractures; Traction; Wound Healing

Topics: Biopsy; Carbohydrate Metabolism; Femur; Fractures, Bone; Glycogen; Muscles; Rats; Research; Statistics as Topic; Tibial Fractures

Topics: Alkaline Phosphatase; Animals; Calcium; Fractures, Bone; Glycogen; Histocytochemistry; Osteogenesis; Rabbits

Topics: Carbohydrate Metabolism; Diaphragm; Diet; Fractures, Bone; Glycogen; Glycogenolysis; Liver Glycogen; Muscles; Rats; Research; Tibia

Topics: Carbohydrate Metabolism; Diaphragm; Extremities; Fractures, Bone; Glycogen; Liver Glycogen; Muscles; Rats; Research; Tibial Fractures