glycogen and Bone-Diseases

glycogen has been researched along with Bone-Diseases* in 5 studies

Reviews

1 review(s) available for glycogen and Bone-Diseases

Article	Year
Non-muscle involvement in late-onset glycogenosis II. Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology, 2013, Volume: 32, Issue:2 Glycogenosis II (GSD II) is an autosomal recessive lysosomal storage disorder resulting from acid alpha-glucosidase deficiency, subsequent accumulation of glycogen in tissues, impairment of autophagic processes and progressive cardiac, motor and respiratory failure. The late-onset form is characterized by wide variability in residual enzyme activity, age of onset, rate of disease progression and phenotypical spectrum. Although the pathological process mainly affects the skeletal muscle, several other tissues may be involved in the course of the disease; therefore GSD II should be regarded as a multisystem disorder in which glycogen accumulation is present in skeletal and smooth muscle, heart, brain, liver, spleen, salivary glands, kidney and blood vessels. In this review, we briefly summarize the main non-muscle targets of the pathological process in late-onset GSD II. Further studies aimed at evaluating the extra-muscle involvement in this group of patients will help to better define clinical features and prognostic factors and to delineate the natural history of the disease. Topics: Age of Onset; alpha-Glucosidases; Bone Diseases; Disease Progression; Glycogen; Glycogen Storage Disease Type II; Humans; Nervous System Diseases; Phenotype; Prognosis; Vascular Diseases	2013

Article

Year

Non-muscle involvement in late-onset glycogenosis II.

Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology, 2013, Volume: 32, Issue:2

Glycogenosis II (GSD II) is an autosomal recessive lysosomal storage disorder resulting from acid alpha-glucosidase deficiency, subsequent accumulation of glycogen in tissues, impairment of autophagic processes and progressive cardiac, motor and respiratory failure. The late-onset form is characterized by wide variability in residual enzyme activity, age of onset, rate of disease progression and phenotypical spectrum. Although the pathological process mainly affects the skeletal muscle, several other tissues may be involved in the course of the disease; therefore GSD II should be regarded as a multisystem disorder in which glycogen accumulation is present in skeletal and smooth muscle, heart, brain, liver, spleen, salivary glands, kidney and blood vessels. In this review, we briefly summarize the main non-muscle targets of the pathological process in late-onset GSD II. Further studies aimed at evaluating the extra-muscle involvement in this group of patients will help to better define clinical features and prognostic factors and to delineate the natural history of the disease.

Topics: Age of Onset; alpha-Glucosidases; Bone Diseases; Disease Progression; Glycogen; Glycogen Storage Disease Type II; Humans; Nervous System Diseases; Phenotype; Prognosis; Vascular Diseases

2013

Other Studies

4 other study(ies) available for glycogen and Bone-Diseases

Article	Year
[Diagnosis of tumors and other bone lesions by the trephine biopsy method]. Voprosy onkologii, 1970, Volume: 16, Issue:8 Topics: Alkaline Phosphatase; Biopsy; Bone Cysts; Bone Diseases; Bone Neoplasms; Chondroma; Chondrosarcoma; Clinical Enzyme Tests; Diagnosis, Differential; Femoral Neoplasms; Fibrosarcoma; Giant Cell Tumors; Glycogen; Hemangioma; Hemangiosarcoma; Histocytochemistry; Humans; Ilium; Lymphoma, Large B-Cell, Diffuse; Multiple Myeloma; Neoplasm Metastasis; Osteoma; Osteoma, Osteoid; Osteomyelitis; Osteosarcoma; Ribs; Sarcoma, Ewing; Tibia; Trephining; Tuberculosis, Osteoarticular	1970
Parathyroid morphology in suppressible and nonsuppressible renal hyperparathyroidism. Laboratory investigation; a journal of technical methods and pathology, 1970, Volume: 23, Issue:5 Topics: Adult; Alkaline Phosphatase; Bone Diseases; Calcium; Cytoplasm; Endoplasmic Reticulum; Female; Glomerular Filtration Rate; Glycogen; Golgi Apparatus; Humans; Hyperparathyroidism, Secondary; Kidney Failure, Chronic; Male; Mitochondria; Organ Size; Parathyroid Glands; Phosphates; Uremia	1970
Histochemical studies on glycogen in bone tumors and related diseases. Oncologia, 1962, Volume: 15 Topics: Bone Diseases; Bone Neoplasms; Chondroma; Chondrosarcoma; Glycogen; Humans; Osteoma; Osteosarcoma	1962
Pigeon breast muscle as an ideal test material for histochemical demonstration of glycogen. Stain technology, 1961, Volume: 36 Topics: Animals; Bone Diseases; Coloring Agents; Columbidae; Glycogen; Muscles; Staining and Labeling; Thoracic Diseases	1961