glycogen and Acanthoma

Topics: Acanthoma; Aged, 80 and over; Dermoscopy; Diagnosis, Differential; Glycogen; Humans; Male; Neoplasms, Multiple Primary; Skin Neoplasms

Clear cell acanthoma, firstly described by Degos as "an epidermal tumor with a particular aspect", although quite a rare lesion, raised an important interest because it may be easily confused with other dermatologic lesions, in the absence of a histopathological examination. Its clinical aspect is of a solitary nodule, with a red-brown varying color, with a size of 3 mm to 2 mm, sometimes covered with a thin scall. We present a case of a multiple rare cell acanthoma (seven nodular formations), having a rapid development (about two months) diagnosed in a 71-year-old patient within the lower 1/3 of the right shin.

Topics: Acanthoma; Aged; B-Lymphocytes; Dermis; Female; Glycogen; Humans; Immunohistochemistry; Inflammation; Keratinocytes; Keratins; Leg; Lymphocyte Count; Skin Neoplasms; T-Lymphocytes

Clear cell acanthoma is a benign epidermal lesion with a variable clinical appearance and distinct histopathology features. Although, it is considered an entirely benign entity, few case reports describe unusual or atypical variants of clear cell acanthoma. We observed a case of a large clear cell acanthoma that also has features of a keratoacanthoma.

Topics: Acanthoma; Biomarkers, Tumor; Diagnosis, Differential; Glycogen; Humans; Keratinocytes; Keratoacanthoma; Male; Middle Aged; Periodic Acid-Schiff Reaction; Skin Neoplasms

Topics: Acanthoma; Glycogen; Humans; Skin Neoplasms