glycocyamine has been researched along with Heart Failure in 3 studies
glycocyamine: RN given refers to parent cpd; structure
guanidinoacetate : A monocarboxylic acid anion that is the conjugate base of guanidinoacetic acid, obtained by deprotonation of the carboxy group.
guanidinoacetic acid : The N-amidino derivative of glycine.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We therefore hypothesised that the consequences of creatine-deficiency in mice would be impaired running capacity, and exacerbation of heart failure following myocardial infarction." | 7.79 | Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice. ( Aksentijevic, D; Balaban, RS; Channon, KM; Clarke, K; Dawson, D; de Bono, JP; Hunyor, I; Lygate, CA; Medway, DJ; Neubauer, S; Phillips, D; Sebag-Montefiore, L; ten Hove, M; Watkins, H; Zervou, S, 2013) |
| "We therefore hypothesised that the consequences of creatine-deficiency in mice would be impaired running capacity, and exacerbation of heart failure following myocardial infarction." | 3.79 | Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice. ( Aksentijevic, D; Balaban, RS; Channon, KM; Clarke, K; Dawson, D; de Bono, JP; Hunyor, I; Lygate, CA; Medway, DJ; Neubauer, S; Phillips, D; Sebag-Montefiore, L; ten Hove, M; Watkins, H; Zervou, S, 2013) |
| "Homoarginine (hArg) is an endogenous, nonproteinogenic amino acid which differs from arginine by an additional methylene (CH2) group in the backbone." | 2.52 | Homoarginine in the renal and cardiovascular systems. ( Alesutan, I; Drechsler, C; Gaksch, M; Grübler, M; Hartaigh, BÓ; Lang, F; März, W; Meinitzer, A; Pilz, S; Tomaschitz, A; Verheyen, N; Voelkl, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pilz, S | 1 |
| Meinitzer, A | 1 |
| Gaksch, M | 1 |
| Grübler, M | 1 |
| Verheyen, N | 1 |
| Drechsler, C | 1 |
| Hartaigh, BÓ | 1 |
| Lang, F | 1 |
| Alesutan, I | 1 |
| Voelkl, J | 1 |
| März, W | 1 |
| Tomaschitz, A | 1 |
| Lygate, CA | 1 |
| Aksentijevic, D | 1 |
| Dawson, D | 1 |
| ten Hove, M | 1 |
| Phillips, D | 1 |
| de Bono, JP | 1 |
| Medway, DJ | 1 |
| Sebag-Montefiore, L | 1 |
| Hunyor, I | 1 |
| Channon, KM | 1 |
| Clarke, K | 1 |
| Zervou, S | 1 |
| Watkins, H | 1 |
| Balaban, RS | 1 |
| Neubauer, S | 1 |
| BORSOOK, ME | 1 |
| BORSOOK, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Medium-term Oral Guanidinoacetic Acid (GAA) Administration on Human Performance, Body Composition, and Metabolic Outcomes in Physically Active Men and Women[NCT01133899] | Phase 1/Phase 2 | 40 participants (Actual) | Interventional | 2010-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for glycocyamine and Heart Failure
| Article | Year |
|---|---|
Homoarginine in the renal and cardiovascular systems.
Topics: Amidinotransferases; Animals; Biomarkers; Cerebrovascular Disorders; Energy Metabolism; Glycine; Hea | 2015 |
2 other studies available for glycocyamine and Heart Failure
| Article | Year |
|---|---|
Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice.
Topics: Adenylate Kinase; Animals; Creatine; Exercise Tolerance; Female; Glycine; Guanidinoacetate N-Methylt | 2013 |
Treatment of cardiac decompensation with betaine and glycocyamine.
Topics: Betaine; Biochemical Phenomena; Cardiovascular Diseases; Creatine; Glycine; Heart Failure; Humans | 1951 |