Page last updated: 2024-10-18

glycocyamine and Aprosodia

glycocyamine has been researched along with Aprosodia in 6 studies

glycocyamine: RN given refers to parent cpd; structure
guanidinoacetate : A monocarboxylic acid anion that is the conjugate base of guanidinoacetic acid, obtained by deprotonation of the carboxy group.
guanidinoacetic acid : The N-amidino derivative of glycine.

Research Excerpts

ExcerptRelevanceReference
" AGAT patients might benefit from oral GAA due to upgraded bioavailability and convenient utilization of the compound, while possible drawbacks (e."2.61Benefits and drawbacks of guanidinoacetic acid as a possible treatment to replenish cerebral creatine in AGAT deficiency. ( Ostojic, SM, 2019)
"Treatment with creatine monohydrate (100-800 mg/kg/day) resulted in almost complete restoration of brain creatine levels and significant improvement of myopathy."1.42Arginine:glycine amidinotransferase (AGAT) deficiency: Clinical features and long term outcomes in 16 patients diagnosed worldwide. ( Apatean, D; Battini, R; DeBrosse, S; Dessoffy, K; Dowling, MD; Edvardson, S; Eichler, F; Johnston, K; Koeller, DM; Nouioua, S; Stockler-Ipsiroglu, S; Tazir, M; Verma, A; Wierenga, AM; Wierenga, KJ; Wong, LJ; Zhang, V, 2015)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Balestrino, M1
Adriano, E1
Neu, A1
Hornig, S1
Sasani, A1
Isbrandt, D1
Gerloff, C1
Tsikas, D1
Schwedhelm, E1
Choe, CU1
Ostojic, SM1
Nouioua, S2
Cheillan, D1
Zaouidi, S1
Salomons, GS1
Amedjout, N1
Kessaci, F1
Boulahdour, N1
Hamadouche, T1
Tazir, M2
Stockler-Ipsiroglu, S1
Apatean, D1
Battini, R1
DeBrosse, S1
Dessoffy, K1
Edvardson, S1
Eichler, F1
Johnston, K1
Koeller, DM1
Verma, A1
Dowling, MD1
Wierenga, KJ1
Wierenga, AM1
Zhang, V1
Wong, LJ1
Braissant, O1
Henry, H1

Reviews

2 reviews available for glycocyamine and Aprosodia

ArticleYear
Benefits and drawbacks of guanidinoacetic acid as a possible treatment to replenish cerebral creatine in AGAT deficiency.
    Nutritional neuroscience, 2019, Volume: 22, Issue:5

    Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Clinical Trials as Topic; Creatine; Devel

2019
AGAT, GAMT and SLC6A8 distribution in the central nervous system, in relation to creatine deficiency syndromes: a review.
    Journal of inherited metabolic disease, 2008, Volume: 31, Issue:2

    Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Brain; Creatine; Developmental D

2008

Other Studies

4 other studies available for glycocyamine and Aprosodia

ArticleYear
Presence of guanidinoacetate may compensate creatine absence and account for less statin-induced muscle damage in GAMT-deficient compared to AGAT-deficient mice.
    Amino acids, 2020, Volume: 52, Issue:4

    Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Creatine; Developmental Disabili

2020
Creatine, guanidinoacetate and homoarginine in statin-induced myopathy.
    Amino acids, 2020, Volume: 52, Issue:6-7

    Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Creatine; Developmental Disabili

2020
Creatine deficiency syndrome. A treatable myopathy due to arginine-glycine amidinotransferase (AGAT) deficiency.
    Neuromuscular disorders : NMD, 2013, Volume: 23, Issue:8

    Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Brain; Child; Creatine; Developmental Dis

2013
Arginine:glycine amidinotransferase (AGAT) deficiency: Clinical features and long term outcomes in 16 patients diagnosed worldwide.
    Molecular genetics and metabolism, 2015, Volume: 116, Issue:4

    Topics: Adolescent; Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Crea

2015