glycochenodeoxycholic acid has been researched along with Necrosis in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Buist-Homan, M; Geng, Y; Moshage, H; Wu, Z | 1 |
| Buist-Homan, M; Conde de la Rosa, L; Faber, KN; Moshage, H; Woudenberg-Vrenken, TE | 2 |
| Antoine, DJ; Clarke, JI; Dorko, K; Fan, F; Forster, J; Gholami, P; Hagenbuch, B; Jaeschke, H; Jenkins, RE; Kumer, SC; Li, F; Olyaee, M; Park, BK; Schmitt, TM; Woolbright, BL | 1 |
| Buist-Homan, M; Faber, KN; Kalsbeek, AJ; Moshage, H; Vrenken, TE | 1 |
| Jaeschke, H; Woolbright, BL | 1 |
| Dahl, R; Devereaux, MW; Gumpricht, E; Sokol, RJ | 1 |
| Dahl, R; Devereaux, MW; Doctor, RB; Gumpricht, E; Kobak, GE; Sokol, RJ; Traber, M | 1 |
| Hatano, E; Ikai, I; Iwaisako, K; Kodama, Y; Nakajima, A; Nitta, T; Seo, S; Tada, M; Tamaki, N; Taura, K; Uemoto, S | 1 |
| Angermüller, S; Benz, C; Klöters-Plachky, P; Riedel, HD; Sauer, P; Stiehl, A; Stremmel, W; Töx, U | 1 |
| Aguilar, HI; Botla, R; Bronk, SF; Gores, GJ; Miyoshi, H | 1 |
| Dahl, RH; Devereaux, MW; Gumpricht, E; Sokol, RJ | 1 |
1 review(s) available for glycochenodeoxycholic acid and Necrosis
| Article | Year |
|---|---|
Novel insight into mechanisms of cholestatic liver injury.
Topics: Animals; Apoptosis; Bile Acids and Salts; Cholestasis; Glycochenodeoxycholic Acid; Hepatocytes; Humans; Ligation; Necrosis; Signal Transduction | 2012 |
11 other study(ies) available for glycochenodeoxycholic acid and Necrosis
| Article | Year |
|---|---|
Scopoletin and umbelliferone protect hepatocytes against palmitate- and bile acid-induced cell death by reducing endoplasmic reticulum stress and oxidative stress.
Topics: Animals; Antioxidants; Apoptosis; Bile Acids and Salts; Cell Death; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glycochenodeoxycholic Acid; Hep G2 Cells; Hepatocytes; Humans; Male; Necrosis; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Palmitates; Rats; Rats, Wistar; Reactive Oxygen Species; Scopoletin; Signal Transduction; Umbelliferones | 2022 |
Metformin protects rat hepatocytes against bile acid-induced apoptosis.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Bile Acids and Salts; Caspase 3; Cell Membrane; Dose-Response Relationship, Drug; Glycochenodeoxycholic Acid; Hepatocytes; Hypoglycemic Agents; Male; Metformin; Necrosis; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; TOR Serine-Threonine Kinases | 2013 |
Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis.
Topics: Acetylation; Animals; Bile Acids and Salts; Biomarkers; Cells, Cultured; Cholestasis, Extrahepatic; Dose-Response Relationship, Drug; Glycochenodeoxycholic Acid; Hepatocytes; HMGB1 Protein; Humans; Jaundice, Obstructive; Keratin-18; Mice, Inbred C57BL; Necrosis; Primary Cell Culture; Species Specificity | 2015 |
The active metabolite of leflunomide, A77 1726, protects rat hepatocytes against bile acid-induced apoptosis.
Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Bile Acids and Salts; Crotonates; Glycochenodeoxycholic Acid; Hepatocytes; Hydroxybutyrates; In Vitro Techniques; Isoxazoles; Leflunomide; Male; MAP Kinase Signaling System; Necrosis; NF-kappa B; Nitriles; Oxidative Stress; Rats; Rats, Wistar; Toluidines; Tumor Necrosis Factor-alpha | 2008 |
Anti-oxidants do not prevent bile acid-induced cell death in rat hepatocytes.
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Cells, Cultured; Cytoprotection; Glycochenodeoxycholic Acid; Heme Oxygenase (Decyclizing); Hepatocytes; Male; NADPH Oxidases; Necrosis; Oxidative Stress; Protein Kinase Inhibitors; Rats; Rats, Wistar; Rats, Zucker; Reactive Oxygen Species; RNA, Messenger; src-Family Kinases; Taurolithocholic Acid | 2010 |
Beta-carotene prevents bile acid-induced cytotoxicity in the rat hepatocyte: Evidence for an antioxidant and anti-apoptotic role of beta-carotene in vitro.
Topics: Animals; Antioxidants; Apoptosis; beta Carotene; Bile Acids and Salts; Caspase 3; Caspases; Cholestasis; Cytochromes c; Cytosol; Enzyme Activation; Flow Cytometry; Glycochenodeoxycholic Acid; Hepatocytes; Immunoblotting; Liver; Membrane Potentials; Mitochondria; Mitochondria, Liver; Necrosis; Oxidative Stress; Rats; Reactive Oxygen Species; Time Factors | 2004 |
Increased susceptibility of fat-laden Zucker-rat hepatocytes to bile acid-induced oncotic necrosis: an in vitro model of steatocholestasis.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Bile Acids and Salts; Caspase Inhibitors; Cell Membrane Permeability; Cytochromes c; Disease Models, Animal; Enzyme Inhibitors; Fatty Liver; Glycochenodeoxycholic Acid; Hepatocytes; Male; Mitochondria, Liver; Necrosis; Nutritional Status; Obesity; Rats; Rats, Zucker; Reactive Oxygen Species | 2005 |
CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Cholagogues and Choleretics; Cholestasis; Endoplasmic Reticulum; Glycochenodeoxycholic Acid; Hepatocytes; Immunohistochemistry; Ligation; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta1 | 2008 |
Effect of tauroursodeoxycholic acid on bile-acid-induced apoptosis and cytolysis in rat hepatocytes.
Topics: Animals; Apoptosis; Aspartate Aminotransferases; Bile Acids and Salts; Cell Death; Cells, Cultured; DNA Fragmentation; Glycochenodeoxycholic Acid; L-Lactate Dehydrogenase; Liver; Male; Necrosis; Rats; Rats, Wistar; Taurochenodeoxycholic Acid | 1998 |
Induction of the mitochondrial permeability transition as a mechanism of liver injury during cholestasis: a potential role for mitochondrial proteases.
Topics: Animals; ATP-Dependent Proteases; Calcium Channels; Calpain; Cholestasis; Enzyme Activation; Glycochenodeoxycholic Acid; Liver; Mitochondria, Liver; Necrosis; Permeability; Serine Endopeptidases; Ursodeoxycholic Acid | 1998 |
Glutathione status of isolated rat hepatocytes affects bile acid-induced cellular necrosis but not apoptosis.
Topics: Animals; Apoptosis; Glutathione; Glutathione Disulfide; Glycochenodeoxycholic Acid; Liver; Male; Necrosis; Rats; Rats, Sprague-Dawley | 2000 |