glycochenodeoxycholic acid has been researched along with Hepatocellular Carcinoma in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (84.62) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, X; Jin, X; Li, B; Liao, M; Wang, C; Wang, J; Yang, M; Zhang, Q; Zhou, M | 1 |
| Hu, L; Liao, B; Qiao, L; Shen, W; Shi, C; Xie, F; Yang, J; Zhu, G | 1 |
| Fan, SF; Li, H; Shen, SG; Sun, DX; Wang, Y | 1 |
| Liao, M; Wen, S; Yang, M; Zhang, Q; Zhao, J; Zhou, M | 1 |
| Jin, X; Li, X; Liao, M; Wang, C; Xiao, X; Yang, M; Zhang, Y; Zhao, J | 1 |
| Gao, L; Han, ZP; Hou, XJ; Jiang, JH; Jing, YY; Li, R; Li, XY; Liu, WT; Lv, G; Wei, LX; Yang, X; Ye, F; Zong, C | 1 |
| Anwer, MS; Webster, CR | 1 |
| Aguilar-Melero, P; de la Mata, M; Ferrín, G; González-Rubio, S; Linares, CI; Montero-Álvarez, JL; Rodríguez-Perálvarez, M | 1 |
| Denk, GU; Pusl, T; Rust, C; Thasler, W; Vennegeerts, T; Wimmer, R | 1 |
| Anwer, MS; Beuers, U; Gates, A; Hohenester, S; Rust, C; Webster, CR; Wimmer, R | 1 |
| Gonzalez-Buitrago, JM; Gonzalez-Loyola, A; Gonzalez-Sanchez, E; Marin, JJ; Perez, MJ | 1 |
| Deng, X; Duan, J; Liao, M; Wang, T; Zhang, Y; Zhao, J | 1 |
| Anwer, MS; Johnston, A; Ponzetti, K; Webster, CR | 1 |
13 other study(ies) available for glycochenodeoxycholic acid and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Glycochenodeoxycholate induces cell survival and chemoresistance via phosphorylation of STAT3 at Ser727 site in HCC.
Topics: Carcinoma, Hepatocellular; Cell Survival; Drug Resistance, Neoplasm; Flavonoids; Fluorouracil; Gene Expression Regulation, Neoplastic; Glycochenodeoxycholic Acid; Hep G2 Cells; Humans; Liver Neoplasms; MAP Kinase Signaling System; Phosphorylation; STAT3 Transcription Factor | 2020 |
Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells.
Topics: Carcinoma, Hepatocellular; Cell Differentiation; Cell Self Renewal; Drug Resistance, Neoplasm; Glycochenodeoxycholic Acid; Humans; Liver Neoplasms; Signal Transduction; STAT3 Transcription Factor; Tumor Cells, Cultured | 2020 |
Rapid Detection of Small Molecule Metabolites in Serum of Hepatocellular Carcinoma Patients Using Ultrafast Liquid Chromatography-Ion Trap-Time of Flight Tandem Mass Spectrometry.
Topics: Acetylcarnitine; Amides; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Glycerylphosphorylcholine; Glycochenodeoxycholic Acid; Glycocholic Acid; Humans; Lysophosphatidylcholines; Oleic Acids; Phenylalanine; Small Molecule Libraries; Tandem Mass Spectrometry | 2017 |
Phosphorylation of Bcl-2 plays an important role in glycochenodeoxycholate-induced survival and chemoresistance in HCC.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glycochenodeoxycholic Acid; Hep G2 Cells; Humans; Liver Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; RNA Interference; Signal Transduction | 2017 |
Bile salt (glycochenodeoxycholate acid) induces cell survival and chemoresistance in hepatocellular carcinoma.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Fluorouracil; Glycochenodeoxycholic Acid; Hep G2 Cells; Humans; Liver Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; STAT3 Transcription Factor; Survivin | 2019 |
Glycochenodeoxycholate promotes hepatocellular carcinoma invasion and migration by AMPK/mTOR dependent autophagy activation.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Female; Glycochenodeoxycholic Acid; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Invasiveness; TOR Serine-Threonine Kinases | 2019 |
Hydrophobic bile acid apoptosis is regulated by sphingosine-1-phosphate receptor 2 in rat hepatocytes and human hepatocellular carcinoma cells.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cells, Cultured; Glycochenodeoxycholic Acid; Hepatocytes; Humans; Liver Neoplasms; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptors, Lysosphingolipid; Sphingosine-1-Phosphate Receptors | 2016 |
AP-1 Inhibition by SR 11302 Protects Human Hepatoma HepG2 Cells from Bile Acid-Induced Cytotoxicity by Restoring the NOS-3 Expression.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cyclin D1; Down-Regulation; Genes, Reporter; Glycochenodeoxycholic Acid; Hep G2 Cells; Humans; Liver Neoplasms; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Retinoids; Transcription Factor AP-1; Up-Regulation | 2016 |
Glycochenodeoxycholate-induced apoptosis is not reduced by augmenter of liver regeneration in the human hepatoma cell line HuH-7.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line; Cholestasis; Glycochenodeoxycholic Acid; Humans; Liver Neoplasms; Liver Regeneration; Polymerase Chain Reaction; Proteins; Rats; Transfection; Tumor Cells, Cultured | 2010 |
Phosphatidylinositol-3-kinase p110γ contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cells.
Topics: Animals; Apoptosis; Bile Acids and Salts; Carcinoma, Hepatocellular; Cells, Cultured; Class Ib Phosphatidylinositol 3-Kinase; Dioxoles; Enzyme Activation; Glycochenodeoxycholic Acid; Hep G2 Cells; Hepatocytes; Humans; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Thiazolidinediones | 2010 |
Mitochondrial genome depletion dysregulates bile acid- and paracetamol-induced expression of the transporters Mdr1, Mrp1 and Mrp4 in liver cells.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Line, Tumor; Gene Expression Regulation; Genome, Mitochondrial; Glycochenodeoxycholic Acid; Liver; Mice; Multidrug Resistance-Associated Proteins; NF-E2-Related Factor 2; Reactive Oxygen Species; RNA, Ribosomal; Ursodeoxycholic Acid | 2011 |
Role of bile salt in regulating Mcl-1 phosphorylation and chemoresistance in hepatocellular carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Carcinogens; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cisplatin; DNA Damage; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glycochenodeoxycholic Acid; Hep G2 Cells; Humans; Liver Neoplasms; Membrane Proteins; Mitogen-Activated Protein Kinases; Myeloid Cell Leukemia Sequence 1 Protein; Phosphorylation; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases | 2011 |
cAMP-guanine exchange factor protection from bile acid-induced hepatocyte apoptosis involves glycogen synthase kinase regulation of c-Jun NH2-terminal kinase.
Topics: Animals; Apoptosis; Bile Acids and Salts; Carcinoma, Hepatocellular; Cyclic AMP; Cytoprotection; Endoplasmic Reticulum; Glycochenodeoxycholic Acid; Glycogen Synthase Kinase 3; Guanine Nucleotide Exchange Factors; Hepatocytes; Humans; JNK Mitogen-Activated Protein Kinases; Male; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; rap1 GTP-Binding Proteins; Rats; Rats, Wistar; Signal Transduction; Stress, Physiological; Thionucleotides; Tumor Cells, Cultured | 2011 |