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glycochenodeoxycholic acid and Cancer of Liver

glycochenodeoxycholic acid has been researched along with Cancer of Liver in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's0 (0.00)29.6817
2010's10 (71.43)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Hu, X; Jin, X; Li, B; Liao, M; Wang, C; Wang, J; Yang, M; Zhang, Q; Zhou, M1
Hu, L; Liao, B; Qiao, L; Shen, W; Shi, C; Xie, F; Yang, J; Zhu, G1
Li, H; Liao, M; Liao, Q; Liu, R; Wei, C; Xia, Z; Xiao, X; Yang, M; Yu, H; Zhang, X; Zhao, J; Zhou, Y1
Liao, M; Wen, S; Yang, M; Zhang, Q; Zhao, J; Zhou, M1
Jin, X; Li, X; Liao, M; Wang, C; Xiao, X; Yang, M; Zhang, Y; Zhao, J1
Gao, L; Han, ZP; Hou, XJ; Jiang, JH; Jing, YY; Li, R; Li, XY; Liu, WT; Lv, G; Wei, LX; Yang, X; Ye, F; Zong, C1
Albanes, D; Derkach, A; Freedman, ND; Keski-Rahkonen, P; Loftfield, E; Robinot, N; Rothwell, JA; Sampson, J; Scalbert, A; Sinha, R; Weinstein, SJ1
Banales, JM; Briz, O; Herraez, E; Lozano, E; Macias, RI; Marin, JJ; Monte, MJ; Sanchez-Vicente, L1
Anwer, MS; Webster, CR1
Aguilar-Melero, P; de la Mata, M; Ferrín, G; González-Rubio, S; Linares, CI; Montero-Álvarez, JL; Rodríguez-Perálvarez, M1
Denk, GU; Pusl, T; Rust, C; Thasler, W; Vennegeerts, T; Wimmer, R1
Anwer, MS; Beuers, U; Gates, A; Hohenester, S; Rust, C; Webster, CR; Wimmer, R1
Deng, X; Duan, J; Liao, M; Wang, T; Zhang, Y; Zhao, J1
Chiang, JY; Heuman, DM; Lucas, V; Pandak, WM; Stravitz, RT1

Other Studies

14 other study(ies) available for glycochenodeoxycholic acid and Cancer of Liver

ArticleYear
Glycochenodeoxycholate induces cell survival and chemoresistance via phosphorylation of STAT3 at Ser727 site in HCC.
    Journal of cellular physiology, 2020, Volume: 235, Issue:3

    Topics: Carcinoma, Hepatocellular; Cell Survival; Drug Resistance, Neoplasm; Flavonoids; Fluorouracil; Gene Expression Regulation, Neoplastic; Glycochenodeoxycholic Acid; Hep G2 Cells; Humans; Liver Neoplasms; MAP Kinase Signaling System; Phosphorylation; STAT3 Transcription Factor

2020
Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells.
    Aging, 2020, 08-03, Volume: 12, Issue:15

    Topics: Carcinoma, Hepatocellular; Cell Differentiation; Cell Self Renewal; Drug Resistance, Neoplasm; Glycochenodeoxycholic Acid; Humans; Liver Neoplasms; Signal Transduction; STAT3 Transcription Factor; Tumor Cells, Cultured

2020
Mcl-1 suppresses abasic site repair following bile acid-induced hepatic cellular DNA damage.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, Volume: 39, Issue:7

    Topics: Apurinic Acid; Bile Acids and Salts; Cholestasis; DNA Damage; DNA Repair; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glycochenodeoxycholic Acid; Hep G2 Cells; Hepatocytes; Humans; Liver Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; X-ray Repair Cross Complementing Protein 1

2017
Phosphorylation of Bcl-2 plays an important role in glycochenodeoxycholate-induced survival and chemoresistance in HCC.
    Oncology reports, 2017, Volume: 38, Issue:3

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glycochenodeoxycholic Acid; Hep G2 Cells; Humans; Liver Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; RNA Interference; Signal Transduction

2017
Bile salt (glycochenodeoxycholate acid) induces cell survival and chemoresistance in hepatocellular carcinoma.
    Journal of cellular physiology, 2019, Volume: 234, Issue:7

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Fluorouracil; Glycochenodeoxycholic Acid; Hep G2 Cells; Humans; Liver Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; STAT3 Transcription Factor; Survivin

2019
Glycochenodeoxycholate promotes hepatocellular carcinoma invasion and migration by AMPK/mTOR dependent autophagy activation.
    Cancer letters, 2019, 07-10, Volume: 454

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Female; Glycochenodeoxycholic Acid; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Invasiveness; TOR Serine-Threonine Kinases

2019
Prospective Investigation of Serum Metabolites, Coffee Drinking, Liver Cancer Incidence, and Liver Disease Mortality.
    Journal of the National Cancer Institute, 2020, 03-01, Volume: 112, Issue:3

    Topics: Aged; Alkaloids; Case-Control Studies; Coffee; Finland; Glycochenodeoxycholic Acid; Glycocholic Acid; Humans; Incidence; Linear Models; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Prospective Studies

2020
Cocarcinogenic effects of intrahepatic bile acid accumulation in cholangiocarcinoma development.
    Molecular cancer research : MCR, 2014, Volume: 12, Issue:1

    Topics: Animals; Apoptosis; Bile Acids and Salts; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biomarkers, Tumor; Cell Proliferation; Cells, Cultured; Cholangiocarcinoma; Cholestasis; Cholic Acids; Cisplatin; Cocarcinogenesis; Cross-Linking Reagents; DNA Damage; Glycochenodeoxycholic Acid; Hepatocytes; Inflammation; Interleukin-6; Liver; Liver Neoplasms; Male; Promoter Regions, Genetic; Rats; Rats, Wistar; Rec A Recombinases; Receptor, ErbB-2; Receptors, Cytoplasmic and Nuclear; SOS Response, Genetics; Thioacetamide

2014
Hydrophobic bile acid apoptosis is regulated by sphingosine-1-phosphate receptor 2 in rat hepatocytes and human hepatocellular carcinoma cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2016, 05-15, Volume: 310, Issue:10

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cells, Cultured; Glycochenodeoxycholic Acid; Hepatocytes; Humans; Liver Neoplasms; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptors, Lysosphingolipid; Sphingosine-1-Phosphate Receptors

2016
AP-1 Inhibition by SR 11302 Protects Human Hepatoma HepG2 Cells from Bile Acid-Induced Cytotoxicity by Restoring the NOS-3 Expression.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: Apoptosis; Carcinoma, Hepatocellular; Cyclin D1; Down-Regulation; Genes, Reporter; Glycochenodeoxycholic Acid; Hep G2 Cells; Humans; Liver Neoplasms; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Retinoids; Transcription Factor AP-1; Up-Regulation

2016
Glycochenodeoxycholate-induced apoptosis is not reduced by augmenter of liver regeneration in the human hepatoma cell line HuH-7.
    Digestion, 2010, Volume: 82, Issue:4

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line; Cholestasis; Glycochenodeoxycholic Acid; Humans; Liver Neoplasms; Liver Regeneration; Polymerase Chain Reaction; Proteins; Rats; Transfection; Tumor Cells, Cultured

2010
Phosphatidylinositol-3-kinase p110γ contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cells.
    Journal of hepatology, 2010, Volume: 53, Issue:5

    Topics: Animals; Apoptosis; Bile Acids and Salts; Carcinoma, Hepatocellular; Cells, Cultured; Class Ib Phosphatidylinositol 3-Kinase; Dioxoles; Enzyme Activation; Glycochenodeoxycholic Acid; Hep G2 Cells; Hepatocytes; Humans; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Thiazolidinediones

2010
Role of bile salt in regulating Mcl-1 phosphorylation and chemoresistance in hepatocellular carcinoma cells.
    Molecular cancer, 2011, Apr-20, Volume: 10

    Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Carcinogens; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cisplatin; DNA Damage; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glycochenodeoxycholic Acid; Hep G2 Cells; Humans; Liver Neoplasms; Membrane Proteins; Mitogen-Activated Protein Kinases; Myeloid Cell Leukemia Sequence 1 Protein; Phosphorylation; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases

2011
Hep G2 cells: a model for studies on regulation of human cholesterol 7alpha-hydroxylase at the molecular level.
    The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 1

    Topics: Animals; Bile Acids and Salts; Cell Survival; Cholesterol 7-alpha-Hydroxylase; Dactinomycin; Feedback; Fluorescent Dyes; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glycochenodeoxycholic Acid; Glycodeoxycholic Acid; Hepatoblastoma; Humans; Kinetics; Liposomes; Liver Neoplasms; Luciferases; Models, Biological; Rats; Recombinant Proteins; RNA, Messenger; Transfection; Tumor Cells, Cultured

1996