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glycine and Uremia

glycine has been researched along with Uremia in 42 studies

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
" In order to elucidate the significance of GAA synthesis in the pancreas, the author measured serum concentration of GAA, creatine, and the renal and pancreatic GAT activity in control, streptozotocin (STZ)-induced diabetic, insulin-treated diabetic, and ethionine-induced acute pancreatitis rats."3.67[Study of impaired metabolism of guanidinoacetic acid in uremia--the compensatory role of the pancreas in guanidinoacetic acid synthesis]. ( Hirata, M, 1989)
"In order to investigate the guanidinoacetic acid (GAA) metabolism in uremia, we have measured serum guanidino compounds in patients with chronic renal failure (CRF) in comparison with normal subjects, and the renal content of GAA and glycine amidinotransferase (GAT) activity in the kidney of experimental CRF rabbits."3.67Impaired metabolism of guanidinoacetic acid in uremia. ( Kuroda, M; Muramoto, H; Takeda, R; Tofuku, Y, 1985)
" We conclude that this mixture and dosage of amino acid analogues can meet the dietary requirements of chronic uremic patients for methionine, valine, leucine and isoleucine."1.26Nitrogen balance of uremic patients receiving branched-chain ketoacids and the hydroxy-analogue of methionine as substitutes for the respective amino acids. ( Mitch, W; Walser, M, 1977)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199032 (76.19)18.7374
1990's7 (16.67)18.2507
2000's2 (4.76)29.6817
2010's1 (2.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zounr, RA1
Khuhawar, MY1
Jahangir, TM1
Alamgir, M1
HOCKADAY, TD1
CLAYTON, JE1
FREDERICK, EW1
SMITH, LH1
Attman, PO1
Ottosson, P1
Samuelsson, O1
Eriksson, UG1
Eriksson-Lepkowska, M1
Fager, G1
Robertz, GM1
Dengler, HJ2
Tofuku, Y3
Kuroda, M2
Muramoto, H4
Takeda, R3
Sterner, G2
Asp, NG1
Dahlqvist, A1
Denneberg, T2
Lindberg, T2
Zimmerman, L2
Jörnvall, H2
Bergström, J2
Fürst, P2
Sjövall, J1
Levillain, O2
Marescau, B2
de Deyn, PP3
Possemiers, I1
Al Banchaabouchi, M1
Tanaka, T1
Nakajima, T1
Howie, MB1
Bourke, E1
Gejyo, F1
Kinoshita, Y1
Ito, G1
Ikenaka, T1
Abiko, T1
Kumikawa, M1
Ishizaki, M1
Takahashi, H1
Sekino, H1
Mitch, W1
Walser, M1
Kopple, JD3
Swendseid, ME2
Dengler, TJ1
Robertz-Vaupel, GM1
Rocić, B1
Breyer, D1
Granić, M1
Milutinović, S1
Druml, W1
Lochs, H1
Roth, E1
Hübl, W1
Balcke, P1
Lenz, K1
Takeda, M1
Kubota, M1
Kiyatake, I1
Tomino, Y1
Koide, H1
Macdonald, RL1
McTigue, JJ1
Henderson, SJ1
Lindup, WE1
Hirata, M2
Wolfson, M1
Haruki, K1
Kaplan, B1
Gotfried, M1
Ravid, M1
Richards, P1
Houghton, BJ1
Brown, CL1
Thompson, E1
Sapico, V1
Shear, L1
Litwack, G1
Krempien, B2
Ritz, E2
Schmidt, G1
Altschule, MD1
Hegedus, ZL1
Matsuda, Y1
Ardelt, W1
Giordano, C1
Shinaberger, JH1
Umezawa, CY1
Manzke, H1
Campanacci, L1
Guarnieri, GF1
Siliprandi, N1
Fiaschi, E1
Czerniak, Z1
Burzyński, S2

Reviews

3 reviews available for glycine and Uremia

ArticleYear
PRIMARY HYPEROXALURIA.
    Medicine, 1964, Volume: 43

    Topics: Adolescent; Ascorbic Acid; Biochemical Phenomena; Biochemistry; Child; Classification; Diet; Genetic

1964
Protein and amino acid metabolism in uremic patients undergoing maintenance hemodialysis.
    Kidney international. Supplement, 1975, Issue:2

    Topics: Adult; Amino Acids; Blood Urea Nitrogen; Body Weight; Dietary Proteins; Glycine; Humans; Male; Middl

1975
[Regulation of synthesis of uric acid as the final stage of nitrogen metabolism].
    Saishin igaku. Modern medicine, 1972, Volume: 27, Issue:4

    Topics: Animals; Chickens; Glutamate-Ammonia Ligase; Glutamates; Glutaminase; Glutamine; Glycine; Humans; Hy

1972

Trials

1 trial available for glycine and Uremia

ArticleYear
Prevention of clot formation during haemodialysis using the direct thrombin inhibitor melagatran in patients with chronic uraemia.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2005, Volume: 20, Issue:9

    Topics: Adult; Aged; Anticoagulants; Antithrombins; Azetidines; Benzylamines; Chronic Disease; Dalteparin; G

2005

Other Studies

38 other studies available for glycine and Uremia

ArticleYear
Improved Gas Chromatographic Determination of Guanidino Compounds Using Isovaleroylacetone and Ethyl Chloroformate as Derivatizing Reagents.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2016, Volume: 32, Issue:2

    Topics: Acetone; Arginine; Boric Acids; Butyrates; Butyric Acid; Calibration; Chromatography, Gas; Creatinin

2016
Endogenous ligand(s) decrease drug--protein binding in uremic sera: a fluorescence probe study.
    Klinische Wochenschrift, 1983, Jul-01, Volume: 61, Issue:13

    Topics: Adult; Clofibrate; Clofibric Acid; Dansyl Compounds; Female; Fluorescent Dyes; Glycine; Humans; Kidn

1983
[A study of guanidine metabolism in uremia, with special reference to serum guanidinoacetic acid in anephric patients].
    Nihon Jinzo Gakkai shi, 1984, Volume: 26, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Animals; Blood Urea Nitrogen; Female; Glycine; Guanidine; Guanidin

1984
Small intestinal dipeptidases and disaccharidases in experimental uremia in rats.
    Nephron, 1980, Volume: 26, Issue:3

    Topics: alpha-Glucosidases; Animals; beta-Galactosidase; Dipeptidases; Disaccharidases; Glycine; Intestinal

1980
In vivo and vitro absorption of amino acids and dipeptides in the small intestine of uremic rats.
    Nephron, 1982, Volume: 31, Issue:3

    Topics: Amino Acids; Animals; Dipeptides; Glucose; Glycine; In Vitro Techniques; Intestinal Absorption; Jeju

1982
Characterization of a double conjugate in uremic body fluids.
    FEBS letters, 1981, Jul-06, Volume: 129, Issue:2

    Topics: Biotransformation; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glucu

1981
A new glycine containing compound with a blocked amino group from uremic body fluids.
    Clinical nephrology, 1980, Volume: 14, Issue:3

    Topics: Amino Acids; Electrophoresis; Glycine; Humans; Uremia

1980
Guanidino compound metabolism in rats subjected to 20% to 90% nephrectomy.
    Kidney international, 1995, Volume: 47, Issue:2

    Topics: Animals; Arginine; Creatine; Glycine; Guanidines; Homoarginine; Kidney; Kidney Failure, Chronic; Mal

1995
Influence of 72% injury in one kidney on several organs involved in guanidino compound metabolism: a time course study.
    Pflugers Archiv : European journal of physiology, 2001, Volume: 442, Issue:4

    Topics: Acute Kidney Injury; Animals; Arginine; Creatine; Creatinine; Glycine; Guanidines; Homoarginine; Kid

2001
Isolation and identification of urinary beta-aspartyl dipeptides and their concentrations in human urine.
    Journal of biochemistry, 1978, Volume: 84, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Aspartic Acid; Child; Dipeptides; Female; Glutamates; Glycine; Human

1978
Metabolism of p-aminobenzoic acid in the perfused livers of chronically uraemic rats.
    Clinical science (London, England : 1979), 1979, Volume: 56, Issue:1

    Topics: 4-Aminobenzoic Acid; Acetylation; Aminobenzoates; Animals; Bile; Glucuronates; Glycine; In Vitro Tec

1979
Identification of beta-aspartylglycine in uremic serum and its toxicity.
    Contributions to nephrology, 1978, Volume: 9

    Topics: Acute Kidney Injury; Animals; Aspartic Acid; Dipeptides; Disease Models, Animal; Female; Glycine; Hu

1978
Identification and synthesis of a tripeptide in ECUM fluid of an uremic patient.
    Biochemical and biophysical research communications, 1978, Jul-28, Volume: 83, Issue:2

    Topics: Glycine; Histidine; Humans; Lysine; Oligopeptides; Renal Dialysis; Uremia

1978
Nitrogen balance of uremic patients receiving branched-chain ketoacids and the hydroxy-analogue of methionine as substitutes for the respective amino acids.
    Clinical nephrology, 1977, Volume: 8, Issue:2

    Topics: Amino Acids, Essential; Glomerular Filtration Rate; Glycine; Humans; Isoleucine; Leucine; Methionine

1977
Albumin binding in uraemia: quantitative assessment of inhibition by endogenous ligands and carbamylation of albumin.
    European journal of clinical pharmacology, 1992, Volume: 43, Issue:5

    Topics: Amino Acid Sequence; Binding, Competitive; Carbamates; Dansyl Compounds; Fluorescent Dyes; Glycine;

1992
The effect of guanidino substances from uremic plasma on insulin binding to erythrocyte receptors in uremia.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1991, Volume: 23, Issue:10

    Topics: Adult; Creatine; Creatinine; Down-Regulation; Erythrocytes; Female; Glycine; Guanidines; Humans; Ins

1991
Utilization of tyrosine dipeptides and acetyltyrosine in normal and uremic humans.
    The American journal of physiology, 1991, Volume: 260, Issue:2 Pt 1

    Topics: Adult; Creatinine; Dipeptides; Female; Glycine; Half-Life; Humans; Kidney Failure, Chronic; Male; Me

1991
Contribution of high concentrations of PTH(1-34) to muscle weakness in uremia by suppression of guanidinoacetic acid synthesis.
    Nephron, 1991, Volume: 57, Issue:3

    Topics: Animals; Creatine; Glycine; In Vitro Techniques; Kidney Tubules; Muscles; Parathyroid Hormone; Pepti

1991
Guanidino compounds that are increased in cerebrospinal fluid and brain of uremic patients inhibit GABA and glycine responses on mouse neurons in cell culture.
    Annals of neurology, 1990, Volume: 28, Issue:5

    Topics: Animals; Brain Chemistry; Cells, Cultured; Creatinine; Drug Synergism; GABA Antagonists; Glycine; Gu

1990
Excretion of the uraemic metabolite 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid in human urine.
    Nephron, 1990, Volume: 55, Issue:2

    Topics: Adult; Chromatography, High Pressure Liquid; Furans; Glycine; Glycoconjugates; Humans; Male; Propion

1990
[Study of impaired metabolism of guanidinoacetic acid in uremia--the compensatory role of the pancreas in guanidinoacetic acid synthesis].
    Nihon Jinzo Gakkai shi, 1989, Volume: 31, Issue:9

    Topics: Acute Disease; Animals; Diabetes Mellitus, Experimental; Ethionine; Glycine; Insulin; Male; Pancreas

1989
The effects of vitamin B-6 deficiency in chronically azotemic and sham-operated rats.
    Kidney international. Supplement, 1987, Volume: 22

    Topics: Alanine; Animals; Asparagine; Aspartate Aminotransferases; Chronic Disease; Creatinine; Erythrocytes

1987
[Metabolism of guanidinoacetic acid and creatine in uremia].
    Nihon Jinzo Gakkai shi, 1988, Volume: 30, Issue:2

    Topics: Animals; Creatine; Female; Glycine; Glycine Transaminase; Guanidines; Humans; Kidney; Male; Middle A

1988
[Impaired metabolism of guanidinoacetic acid in uremia, with special reference to diabetic nephropathy].
    Nihon Jinzo Gakkai shi, 1988, Volume: 30, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amidinotransferases; Diabetic Nephropathies; Female; Glycine; Humans

1988
Amino acid containing compounds in uremic serum-search for middle molecules by high performance liquid chromatography.
    Clinical nephrology, 1986, Volume: 26, Issue:2

    Topics: Amino Acids; Chromatography, High Pressure Liquid; Glutamine; Glycine; Humans; Molecular Weight; Ure

1986
Impaired metabolism of guanidinoacetic acid in uremia.
    Nephron, 1985, Volume: 41, Issue:2

    Topics: Adult; Aged; Amidinotransferases; Animals; Female; Glycine; Guanidines; Humans; Kidney; Male; Middle

1985
Synthesis of phenylalanine and valine by healthy and uraemic men.
    Lancet (London, England), 1971, Jul-17, Volume: 2, Issue:7716

    Topics: Adult; Amino Acids; Ammonium Chloride; Carbon; Diet; Female; Glycine; Humans; Keto Acids; Kidney; Ki

1971
Translocation of inducible tyrosine aminotransferase to the mitochondrial fraction. Facilitation by acute uremia and other conditions.
    The Journal of biological chemistry, 1974, Apr-10, Volume: 249, Issue:7

    Topics: Acute Disease; Animals; Antigen-Antibody Reactions; Aspartate Aminotransferases; Biological Transpor

1974
[Experimental autoradiographic investigations of the collagen metabolism of bone in uremia].
    Zeitschrift fur Orthopadie und ihre Grenzgebiete, 1972, Volume: 110, Issue:1

    Topics: Acute Kidney Injury; Animals; Autoradiography; Bone and Bones; Collagen; Glycine; Kidney Failure, Ch

1972
Orthohydroxyhippuric (salicyluric) acid--its physiologic and clinical significance.
    Clinical pharmacology and therapeutics, 1974, Volume: 15, Issue:2

    Topics: Anemia; Animals; Cattle; Dihydroxyphenylalanine; Dogs; Down Syndrome; Fever; Glycine; Humans; Hypert

1974
[Studies on the clinical significance of glycyl-L-leucine dipeptidase in blood platelets].
    Arztliche Forschung, 1972, Aug-10, Volume: 26, Issue:8

    Topics: Adult; Age Factors; Aprotinin; Blood Platelets; Blood Preservation; Carcinoma; Contraceptives, Oral;

1972
Diet and aminoacids in uraemia.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1972, Volume: 9

    Topics: Amino Acids; Amino Acids, Essential; Carbon Radioisotopes; Diet; Dietary Proteins; Glycine; Humans;

1972
The free and bound amino acids removed by hemodialysis.
    Transactions - American Society for Artificial Internal Organs, 1973, Volume: 19

    Topics: Adult; Alanine; Amino Acids; Asparagine; Aspartic Acid; Blood Flow Velocity; Blood Glucose; Body Wei

1973
Experimental renal osteopathy.
    Israel journal of medical sciences, 1971, Volume: 7, Issue:3

    Topics: Animals; Autoradiography; Bone and Bones; Bone Diseases; Calcium; Calcium Isotopes; Glycine; Male; N

1971
[Hyperuricemia with cerebral paresis. Syndrome of a hereditary purine metabolic disorder].
    Helvetica paediatrica acta, 1967, Volume: 22, Issue:3

    Topics: Adolescent; Anemia, Macrocytic; Cerebral Palsy; Child; Child, Preschool; Glycine; Humans; Hyperlipid

1967
Metabolic studies of acetoacetate, pyruvate, lactate and citrate in uremic acidosis.
    Clinica chimica acta; international journal of clinical chemistry, 1968, Volume: 20, Issue:2

    Topics: Acetoacetates; Acidosis; Analysis of Variance; Chronic Disease; Citrates; Citric Acid Cycle; Creatin

1968
Free amino acids in serum of patients with chronic renal insufficiency.
    Clinica chimica acta; international journal of clinical chemistry, 1969, Volume: 24, Issue:3

    Topics: Adult; Aged; Alanine; Amino Acids; Analysis of Variance; Arginine; Chromatography, Paper; Cystine; F

1969
Bound amino acids in serum of patients with chronic renal insufficiency.
    Clinica chimica acta; international journal of clinical chemistry, 1969, Volume: 25, Issue:2

    Topics: Adult; Aged; Amino Acids; Analysis of Variance; Aspartic Acid; Chromatography, Paper; Female; Glomer

1969