Page last updated: 2024-10-18

glycine and Tremor

glycine has been researched along with Tremor in 13 studies

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"Relative to wild-type (WT) mice, the tremor mice presented: increased tremors and bradykinesia associated with postural instability, decreased range of motion, and difficulty in initiating voluntary movements directly proportional to age; reduced step length for right and left hindlimbs; reduced cortical GABA, glutamate and, aspartate levels, the DOPAC/DA and ratio and increased the NOR levels; in the striatum, the levels of glycine and aspartate were reduced while the HVA levels, the HVA/DA and 5HIAA/5-HT ratios increased; in the cerebellum the glycine, NOR and 5-HIAA levels increased."4.31Progressive tremor and motor impairment in seizure-prone mutant tremor mice are associated with neurotransmitter dysfunction. ( Alexandre-Ribeiro, SR; Bernardi, MM; Bondan, EF; Coque, AC; Flório, JC; Garcia-Gomes, MSA; Gonçalves, FB; Kirsten, TB; Lebrun, I; Massironi, SMG; Mori, CMC; Sandini, TM; Silva-Sampaio, AC, 2023)
"Concentrations of putative neuroactive substances glutamate, aspartate, gamma-aminobutyric acid, glycine, proline and ethanolamine were determined in ventricular cerebrospinal fluid collected in patients suffering from Parkinson's disease, pain syndromes or cerebellar tremor."3.67Ventricular cerebrospinal fluid concentrations of putative amino acid transmitters in Parkinson's disease and other disorders. ( Amsler, U; Cuénod, M; Perschak, H; Siegfried, J; Vischer, A, 1987)
"Glycine and GABA administered intraventricularly and intrastriatally were found to inhibit the oxotremorin tremor in rats."3.65[Effect of various amino acids and their antagonists on the cholinergic tremor and acetylcholine release in the CNS of the rat]. ( Oelszner, W; Scherber, A; Staib, AH, 1975)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's1 (7.69)18.2507
2000's4 (30.77)29.6817
2010's0 (0.00)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Gonçalves, FB1
Garcia-Gomes, MSA1
Silva-Sampaio, AC1
Kirsten, TB1
Bondan, EF1
Sandini, TM1
Flório, JC1
Lebrun, I1
Coque, AC1
Alexandre-Ribeiro, SR1
Massironi, SMG1
Mori, CMC1
Bernardi, MM1
O'Shea, SM1
Becker, L2
Weiher, H2
Betz, H1
Laube, B1
Liang, TW1
Truax, AC1
Trojanowski, JQ1
Lee, VM1
Stern, MB1
Kotzbauer, PT1
Hanaya, R1
Kiura, Y1
Kurisu, K1
Sakai, N1
Serikawa, T1
Sasa, M1
von Wegerer, J1
Schenkel, J1
Zeilhofer, HU1
Swandulla, D1
Björkman, S1
Castensson, S2
Lindeke, B2
Sievertsson, H2
Scherber, A1
Staib, AH1
Oelszner, W1
Yu, PH1
Davis, BA1
Perschak, H1
Amsler, U1
Vischer, A1
Siegfried, J1
Cuénod, M1
Kar, PP1
Matin, MA1
Sum, CY1
Laborit, H1
Baron, C1
Laurent, J1
Gründig, E1
Gerstenbrand, F1

Other Studies

13 other studies available for glycine and Tremor

ArticleYear
Progressive tremor and motor impairment in seizure-prone mutant tremor mice are associated with neurotransmitter dysfunction.
    Behavioural brain research, 2023, 04-12, Volume: 443

    Topics: Animals; Aspartic Acid; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine;

2023
Propofol restores the function of "hyperekplexic" mutant glycine receptors in Xenopus oocytes and mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Mar-03, Volume: 24, Issue:9

    Topics: Anesthetics, Intravenous; Animals; Ataxia; Behavior, Animal; Cells, Cultured; Dose-Response Relation

2004
Partial deficit of pantothenate kinase 2 catalytic activity in a case of tremor-predominant neurodegeneration with brain iron accumulation.
    Movement disorders : official journal of the Movement Disorder Society, 2006, Volume: 21, Issue:5

    Topics: Arginine; Brain; DNA Mutational Analysis; Glycine; Humans; Iron; Isoleucine; Male; Middle Aged; Muta

2006
N-acetyl-L-aspartate activates hippocampal CA3 neurons in rodent slice preparations.
    Brain research bulletin, 2008, Mar-28, Volume: 75, Issue:5

    Topics: Animals; Aspartic Acid; Cadmium; Dioxolanes; Disease Models, Animal; Drug Interactions; Electric Sti

2008
Disease-specific human glycine receptor alpha1 subunit causes hyperekplexia phenotype and impaired glycine- and GABA(A)-receptor transmission in transgenic mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Apr-01, Volume: 22, Issue:7

    Topics: Animals; Autoradiography; Brain; Disease Models, Animal; Female; Genes, Dominant; Glycine; Humans; I

2002
Peptides related to melanostatin (Pro-Leu-Gly-NH2) as inhibitors of oxotremorine-induced tremor.
    Acta pharmaceutica Suecica, 1976, Volume: 13, Issue:4

    Topics: Animals; Glycine; Leucine; Male; Mice; MSH Release-Inhibiting Hormone; Oxotremorine; Peptides; Proli

1976
[Effect of various amino acids and their antagonists on the cholinergic tremor and acetylcholine release in the CNS of the rat].
    Acta biologica et medica Germanica, 1975, Volume: 34, Issue:9

    Topics: Acetylcholine; Aminobutyrates; Animals; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glycine;

1975
Simultaneous delivery of valproic acid and glycine to the brain. Deamination of 2-propylpentylglycinamide by monoamine oxidase B.
    Molecular and chemical neuropathology, 1991, Volume: 15, Issue:1

    Topics: Animals; Brain; Deamination; Glycine; In Vitro Techniques; Kinetics; Male; Mice; Monoamine Oxidase;

1991
Ventricular cerebrospinal fluid concentrations of putative amino acid transmitters in Parkinson's disease and other disorders.
    Human neurobiology, 1987, Volume: 6, Issue:3

    Topics: Adult; Aged; Amino Acids; Aspartic Acid; Ethanolamine; Ethanolamines; Female; gamma-Aminobutyric Aci

1987
Possible role of cerebral amino acids in acute neurotoxic effects of DDT in mice.
    European journal of pharmacology, 1974, Volume: 25, Issue:1

    Topics: Amino Acids; Animals; Behavior, Animal; Brain; Brain Chemistry; DDT; gamma-Aminobutyric Acid; Glycin

1974
Studies on the inhibition of oxotremorine induced tremor by a melanocyte-stimulating hormone release-inhibiting factor, thyrotropin releasing hormone and related peptides.
    FEBS letters, 1974, Aug-15, Volume: 44, Issue:1

    Topics: Animals; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Glutamates; Glycine; Histidin

1974
[Inhibition by (intraventricular) glycine of the tremorigenic activity of oxotremorine in the rabbit].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1974, Volume: 15, Issue:1

    Topics: Animals; Brain; Caudate Nucleus; Cerebral Ventricles; Corpus Striatum; Glycine; Injections; Male; Ox

1974
[Correlation between Parkinsonism symptoms and a disorder in the amino acid metabolism in CNS].
    Wiener klinische Wochenschrift, 1970, Nov-06, Volume: 82, Issue:45

    Topics: Amino Acids; Animals; Brain Injuries; Central Nervous System Diseases; Cerebrospinal Fluid; Cysteine

1970