glycine has been researched along with Thyroid Carcinoma, Anaplastic in 2 studies
Thyroid Carcinoma, Anaplastic: An aggressive THYROID GLAND malignancy which generally occurs in IODINE-deficient areas in people with previous thyroid pathology such as GOITER. It is associated with CELL DEDIFFERENTIATION of THYROID CARCINOMA (e.g., FOLLICULAR THYROID CARCINOMA; PAPILLARY THYROID CANCER). Typical initial presentation is a rapidly growing neck mass which upon metastasis is associated with DYSPHAGIA; NECK PAIN; bone pain; DYSPNEA; and NEUROLOGIC DEFICITS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Anaplastic thyroid cancer (ATC) is one of the most aggressive and lethal tumor types, characterized by loss of differentiation, epithelial-to-mesenchymal transition, extremely high proliferation rate, and generalized resistance to therapy." | 1.91 | Anaplastic thyroid cancer cells upregulate mitochondrial one-carbon metabolism to meet purine demand, eliciting a critical targetable vulnerability. ( Di Cristofano, A; Huynh, LD; Shabro, A; Sugarman, AJ, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sugarman, AJ | 1 |
| Huynh, LD | 1 |
| Shabro, A | 1 |
| Di Cristofano, A | 1 |
| Kim, SH | 1 |
| Kang, JG | 1 |
| Kim, CS | 1 |
| Ihm, SH | 1 |
| Choi, MG | 1 |
| Yoo, HJ | 1 |
| Lee, SJ | 1 |
2 other studies available for glycine and Thyroid Carcinoma, Anaplastic
| Article | Year |
|---|---|
Anaplastic thyroid cancer cells upregulate mitochondrial one-carbon metabolism to meet purine demand, eliciting a critical targetable vulnerability.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Glycine; Humans; Mice; Purines; Thyroid Carcinoma, An | 2023 |
The heat shock protein 90 inhibitor SNX5422 has a synergistic activity with histone deacetylase inhibitors in induction of death of anaplastic thyroid carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Caspase 3; Cell Line, Tumor; Cell Survival; Drug Syner | 2016 |