Page last updated: 2024-10-18

glycine and Thalassemias

glycine has been researched along with Thalassemias in 37 studies

Research Excerpts

ExcerptRelevanceReference
"After administration of glycine-2-(14)C to a patient with thalassemia, the specific activities of heme and globin of F hemoglobin were consistently higher than those of hemoglobin A."7.64Heme and globin synthesis control: observations in vivo in beta thalassemia. ( Bannerman, RM; Kreimer-Birnbaum, M, 1967)
"The biosynthesis of two types of human fetal hemoglobin (Hb F), namely Hb F with G gamma chains having glycine in position 136 and Hb F with A gamma chains having alanine in position 136, was studied in blood samples and in cultures of erythroid precursors from blood of patients with different hemoglobinopathies."3.66The synthesis of fetal hemoglobin types in red blood cells and in BFU-E derived colonies from peripheral blood of patients with sickle cell anemia, beta+ - and delta beta-thalassemia, various forms of hereditary persistence of fetal hemoglobin, normal adu ( Efremov, GD; Gravely, ME; Harris, HF; Howard, JS; Huisman, TH; Reese, AL; Wilson, JB, 1979)
" In Greek double heterozygotes for beta-thalassemia and the hereditary persistence of fetal hemoglobin, fetal hemoglobin is increased above the level of hemoglobin F in simple heterozygotes and gamma-chains with glycine in position 136 become apparent."3.65Nature of fetal hemoglobin in the Greek type of hereditary persistence of fetal hemoglobin with and without concurrent beta-thalassemia. ( Apell, G; Bouver, N; Huisman, TH; Schroeder, WA; Shelton, JB; Shelton, JR; Stamatoyannopoulos, G, 1970)
"After administration of glycine-2-(14)C to a patient with thalassemia, the specific activities of heme and globin of F hemoglobin were consistently higher than those of hemoglobin A."3.64Heme and globin synthesis control: observations in vivo in beta thalassemia. ( Bannerman, RM; Kreimer-Birnbaum, M, 1967)
"The rate of endogenous carbon monoxide production ( Vco), determined by the closed rebreathing system technique, was elevated above the normal range in four of five patients studied with ineffective erythropoiesis (four patients with primary refractory anemia, one with thalassemia)."3.64Carbon monoxide production associated with ineffective erythropoiesis. ( Coburn, RF; Goldwein, MI; Rother, ML; Shafer, BC; White, P; Williams, WJ, 1967)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199036 (97.30)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (2.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Basak, J1
Bhattacharyya, DM1
Mukhopadhyay, A1
YAMAMOTO, T2
VAVRA, JD1
MAYER, VK1
MOORE, CV1
NOTARIO, A1
DONEDA, G1
ZANETTI, A1
DIMARCO, N1
GABUZDA, TG2
NATHAN, DG2
GARDNER, FH2
GRECO, AV1
CARBONIN, PU1
BORGATTI, L1
GAMBASSI, G1
Schettini, F1
Costa, S1
Zimbalatti, F1
Fanciulli, G1
Kreimer-Birnbaum, M4
Bannerman, RM4
White, P1
Coburn, RF1
Williams, WJ1
Goldwein, MI1
Rother, ML1
Shafer, BC1
Brennan, SO1
Williamson, D1
Smith, MB1
Cauchi, MN1
Macphee, A1
Carrell, RW1
de Pablos Gallego, JM1
Cano Trapero, R1
Saglio, G1
Camaschella, C1
Guerrasio, A1
Cambrin, GR1
Capaldi, A1
Pich, PG1
Trento, M1
Mazza, U2
Nastev, D1
Efremov, GD4
Petkov, G1
Clegg, JB3
Metaxatou-Mavromati, A2
Kattamis, C2
Sofroniadou, K1
Wood, WG3
Weatherall, DJ3
Amin, AB1
Pandya, NL1
Diwin, PP1
Darbre, PD1
White, JM1
Lie-Injo, LE1
Randhawa, ZI1
Kane, JP1
Ganesan, J1
George, R1
Alter, BP1
Huisman, TH9
Reese, AL1
Howard, JS1
Gravely, ME1
Harris, HF1
Wilson, JB2
Musumeci, S1
Schilirò, G1
Pizzarelli, G1
Tentori, L1
Marinucci, M1
Fontanarosa, PP1
Russo, G1
Anderson, WF2
Schroeder, WA8
Duma, H1
Mladenovski, B1
Hyman, CB1
Rachmilewitz, EA1
Bouver, N6
Miller, A1
Brodie, A1
Shelton, JR7
Shelton, JB7
Apell, G7
Takaku, F1
Yano, Y1
Aoki, Y1
Nakao, K1
Wada, O1
Crystal, RG1
Elson, NA1
Nienhuis, A1
Thornton, AC1
Sukumaran, PK2
Sadikario, A1
Stojmirovic, E1
Brodie, AR1
Mann, JR1
MacNeish, AS1
Bannister, D1
McCurdy, PR1
Freehafer, JT1
Stamatoyannopoulos, G2
Pinkerton, PH1
Kramer, S1
Viljoen, E1
Becker, D1
Zail, SS1
Metz, J1
Charache, S1
Bethlenfalvay, NC1
Massaro, AL1
Bianco, G1
Accatino, G1
Prato, V1

Reviews

2 reviews available for glycine and Thalassemias

ArticleYear
[ON THE SHUNT HYPERBILIRUBINEMIA].
    Naika hokan. Japanese archives of internal medicine, 1964, Volume: 11

    Topics: Anemia; Anemia, Hypochromic; Anemia, Pernicious; Anemia, Sickle Cell; Bilirubin; Blood Chemical Anal

1964
[Synthesis of bilirubin].
    Naika hokan. Japanese archives of internal medicine, 1968, Volume: 15, Issue:11

    Topics: Anemia, Aplastic; Animals; Bilirubin; Carbon Isotopes; Dogs; Feces; Glycine; Heme; Humans; Hyperbili

1968

Other Studies

35 other studies available for glycine and Thalassemias

ArticleYear
Fannin-Lubbock-I [α₂β₂¹¹⁹(GLY>ASP)], a rare mutation in the beta-globin gene, has been detected for the first time in a Hindu Brahmin family in West Bengal, India.
    Cellular & molecular biology letters, 2014, Volume: 19, Issue:2

    Topics: Adult; Asian People; Aspartic Acid; Base Sequence; Codon; Female; Glycine; Haplotypes; Hemoglobins,

2014
IN VITRO HEME SYNTHESIS BY HUMAN BLOOD: ABNORMAL HEME SYNTHESIS IN THALASSEMIA MAJOR.
    The Journal of laboratory and clinical medicine, 1964, Volume: 63

    Topics: beta-Thalassemia; Blood; Carbon Isotopes; Erythrocytes; Glycine; Heme; Hemoglobins; Humans; In Vitro

1964
[ERTHROCYTE METABOLISM OF GLYCINE-1-C14, CYSTINE-S35 AND RADIOSULFATE-S35 IN COOLEY'S DISEASE].
    Haematologica, 1964, Volume: 49

    Topics: Carbon Isotopes; Child; Cystine; Erythrocytes; Glycine; Metabolism; Sulfates; Sulfur Isotopes; Thala

1964
THE METABOLISM OF THE INDIVIDUAL C14 LABELED HEMOGLOBINS IN PATIENTS WITH H-THALASSEMIA, WITH OBSERVATIONS ON RADIOCHROMATE BINDING TO THE HEMOGLOBINS DURING RED CELL SURVIVAL.
    The Journal of clinical investigation, 1965, Volume: 44

    Topics: Blood Protein Electrophoresis; Carbon Isotopes; Cell Survival; Centrifugation; Chromium Isotopes; Er

1965
[ON ERYTHROCYTE METABOLISM IN COOLEY'S DISEASE. INCORPORATION OF 1-C 14 GLYCINE IN GLUTATHIONE].
    La Riforma medica, 1965, Jun-12, Volume: 79

    Topics: Child; Erythrocytes; Fabaceae; Glutathione; Glycine; Humans; Metabolism; Thalassemia

1965
Haemoglobin synthesis from thalassemic reticulocytes. In vitro studies with Fe59 and Glycine-2-C14.
    Annales paediatrici. International review of pediatrics, 1966, Volume: 207, Issue:6

    Topics: Carbon Isotopes; Child; Globins; Glycine; Heme; Hemoglobins; Humans; Iron Isotopes; Radiometry; Reti

1966
Heme and globin synthesis control: observations in vivo in beta thalassemia.
    Science (New York, N.Y.), 1967, Mar-03, Volume: 155, Issue:3766

    Topics: Blood Proteins; Carbon Isotopes; Globins; Glycine; Heme; Hemoglobins; Humans; Mutation; Thalassemia

1967
Hemoglobin F and beta thalassemia.
    Science (New York, N.Y.), 1967, Sep-01, Volume: 157, Issue:3792

    Topics: Blood Transfusion; Carbon Isotopes; Fetal Hemoglobin; Glycine; Hemoglobins; Humans; Thalassemia

1967
Carbon monoxide production associated with ineffective erythropoiesis.
    The Journal of clinical investigation, 1967, Volume: 46, Issue:12

    Topics: Adolescent; Adult; Aged; Anemia; Anemia, Sideroblastic; Bile Pigments; Bilirubin; Carbon Isotopes; C

1967
HbA2 Victoria delta 24 (B6) Gly----Asp. A new delta chain variant occurring with beta-thalassemia.
    Hemoglobin, 1984, Volume: 8, Issue:2

    Topics: Amino Acid Sequence; Aspartic Acid; Female; Genes; Genetic Variation; Glycine; Hemoglobins, Abnormal

1984
[Experience with a simple microchromatographic method for hemoglobin A2 quantification (Hb a2)].
    Sangre, 1984, Volume: 29, Issue:3

    Topics: Chromatography, DEAE-Cellulose; Female; Glycine; Hemoglobin A; Hemoglobin A2; Hemoglobinometry; Hete

1984
G gamma and a gamma globin chain synthesis in bone marrow and peripheral blood of beta-thalassaemia homozygotes.
    British journal of haematology, 1982, Volume: 52, Issue:2

    Topics: Adolescent; Adult; Alanine; Blood Cells; Bone Marrow; Cells, Cultured; Female; Globins; Glycine; Hom

1982
A test tube method for quantitation of hemoglobin A2 using DE 52 cellulose.
    Hemoglobin, 1977, Volume: 1, Issue:5

    Topics: Buffers; Child; Chlorides; Chromatography, DEAE-Cellulose; Cyanates; Glycine; Hemoglobin A; Hemoglob

1977
Occurrence of G gamma Hb F in Greek HPFH: analysis of heterozygotes and compound heterozygotes with beta thalassaemia.
    British journal of haematology, 1979, Volume: 43, Issue:4

    Topics: Adult; Alanine; Erythrocyte Indices; Female; Fetal Hemoglobin; Globins; Glycine; Greece; Hemoglobin

1979
A comparison of the homozygous states for G gamma and G gamma A gamma delta beta thalassaemia.
    British journal of haematology, 1979, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Alanine; Child; Child, Preschool; Female; Fetal Hemoglobin; Glycine; Hemoglobins;

1979
Heterogeneity of hemoglobin gamma chains in normal newborns and in cases of alpha and beta thalassemia.
    American journal of hematology, 1979, Volume: 6, Issue:1

    Topics: Alanine; Cyanogen Bromide; Fetal Hemoglobin; Glycine; Homozygote; Humans; Infant, Newborn; Peptides;

1979
The G gamma:A gamma composition of fetal hemoglobin in fetuses and newborns.
    Blood, 1979, Volume: 54, Issue:5

    Topics: Alanine; Anemia, Sickle Cell; Electrophoresis, Polyacrylamide Gel; Female; Fetal Hemoglobin; Fetus;

1979
The synthesis of fetal hemoglobin types in red blood cells and in BFU-E derived colonies from peripheral blood of patients with sickle cell anemia, beta+ - and delta beta-thalassemia, various forms of hereditary persistence of fetal hemoglobin, normal adu
    Hemoglobin, 1979, Volume: 3, Issue:4

    Topics: Adult; Alanine; Anemia, Sickle Cell; Cells, Cultured; Chromatography, High Pressure Liquid; Clone Ce

1979
Hemoglobin G San José [beta 2 7 (A4) Glu to Gly alpha 2], beta thalassemia, and alpha thalassemia in a Sicilian family.
    Human genetics, 1979, Volume: 52, Issue:2

    Topics: Child, Preschool; Female; Genetic Carrier Screening; Genetic Variation; Glutamates; Glycine; Hemoglo

1979
Isolation and translation of messenger RNA from beta-thalassemia red cells.
    Annals of the New York Academy of Sciences, 1974, Volume: 232, Issue:0

    Topics: Anemia; Anemia, Sickle Cell; Animals; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Cell-Fre

1974
The present status of the heterogeneity of fetal hemoglobin in beta-thalassemia: an attempt to unify some observations in thalassemia and related conditions.
    Annals of the New York Academy of Sciences, 1974, Volume: 232, Issue:0

    Topics: Amino Acid Sequence; Amino Acids; Black People; Chromatography, Ion Exchange; Cyanogen Bromide; Dext

1974
-Aminolevulinic acid synthetase activity of human bone marrow erythroid cells in various hematological disorders.
    The Tohoku journal of experimental medicine, 1972, Volume: 107, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Anemia, Hypochromic; Anemia, Sideroblastic; Bone Marrow; Bone Marrow C

1972
Initiation of globin synthesis in beta-thalassemia.
    The New England journal of medicine, 1973, 05-24, Volume: 288, Issue:21

    Topics: Adult; Amino Acid Sequence; Animals; Carbon Isotopes; Cell-Free System; Dipeptides; Erythroblastosis

1973
A second type of hereditary persistence of foetal haemoglobin in India.
    British journal of haematology, 1973, Volume: 25, Issue:1

    Topics: Adult; Alanine; Amino Acid Sequence; Child; Child, Preschool; Female; Fetal Hemoglobin; Globins; Gly

1973
Chemical heterogeneity of foetal haemoglobin in the Lepore haemoglobinopathy.
    British journal of haematology, 1974, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Alanine; Amino Acid Sequence; Chemical Phenomena; Chemistry; Child; Chromatograph

1974
Delta-beta-thalassaemia in a Chinese family.
    British journal of haematology, 1972, Volume: 23, Issue:4

    Topics: Adult; Alanine; Asian People; Black People; Carbon Isotopes; Child; Child, Preschool; Chromatography

1972
A homozygote for the Hb G type of foetal haemoglobin in India: a study of two Indian and four Negro families.
    British journal of haematology, 1972, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Black People; Child; Child, Preschool; District of Col

1972
Nature of foetal haemoglobin in F-thalassaemia.
    British journal of haematology, 1971, Volume: 21, Issue:6

    Topics: Cyanogen Bromide; Fetal Hemoglobin; Genes; Glycine; Hemoglobins, Abnormal; Heterozygote; Homozygote;

1971
Recent studies on pyrrole metabolism in thalassemia.
    Annals of the New York Academy of Sciences, 1969, Nov-20, Volume: 165, Issue:1

    Topics: Adult; Bile Pigments; Blood Protein Electrophoresis; Carbon Isotopes; Glycine; Hematocrit; Hemoglobi

1969
The relationship between haem and globin synthesis by erythroid precursors in refractory normoblastic anaemia.
    Scandinavian journal of haematology, 1969, Volume: 6, Issue:5

    Topics: Anemia, Hypochromic; Anemia, Pernicious; Anemia, Sideroblastic; Blood Proteins; Carbon Isotopes; Ery

1969
Nature of fetal hemoglobin in the Greek type of hereditary persistence of fetal hemoglobin with and without concurrent beta-thalassemia.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:5

    Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Chromatography, Paper; Fetal Hemoglobin; Glycine; Hem

1970
Heterogeneity of fetal hemoglobin in beta-thalassemia of the Negro.
    American journal of human genetics, 1970, Volume: 22, Issue:5

    Topics: Adolescent; Adult; Aged; Black or African American; Blood Protein Electrophoresis; Chemical Phenomen

1970
Hereditary persistence of fetal hemoglobin. Heterogeneity of fetal hemoglobin in homozygotes and in conjunction with -thalassemia.
    The New England journal of medicine, 1971, Sep-23, Volume: 285, Issue:13

    Topics: Amino Acid Sequence; Black People; Chemical Phenomena; Chemistry; Chromatography; Female; Fetal Hemo

1971
Interrelationship of pyrrole and globin metabolism in beta-thalassaemia.
    British journal of haematology, 1968, Volume: 15, Issue:1

    Topics: Adult; Bile Pigments; Blood Proteins; Carbon Isotopes; Feces; Globins; Glycine; Hemoglobins; Humans;

1968
[Changes in porphyrin metabolism after double overloads of glycine. 3. In patients with porphyria cutanea tarda and of anemias of various origins].
    Bollettino della Societa italiana di biologia sperimentale, 1965, Sep-30, Volume: 41, Issue:18

    Topics: Anemia; Anemia, Macrocytic; Glycine; Humans; Lead Poisoning; Methemoglobinemia; Porphyrias; Porphyri

1965