glycine has been researched along with TDP-43 Proteinopathies in 2 studies
TDP-43 Proteinopathies: Diseases characterized by the presence of abnormally phosphorylated, ubiquitinated, and cleaved DNA-binding protein TDP-43 in affected brain and spinal cord. Inclusions of the pathologic protein in neurons and glia, without the presence of AMYLOID, is the major feature of these conditions, thus making these proteinopathies distinct from most other neurogenerative disorders in which protein misfolding leads to brain amyloidosis. Both frontotemporal lobar degeneration and AMYOTROPHIC LATERAL SCLEROSIS exhibit this common method of pathogenesis and thus they may represent two extremes of a continuous clinicopathological spectrum of one disease.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| An, S | 1 |
| Zhang, X | 1 |
| Shi, Y | 1 |
| Zhang, J | 1 |
| Wan, Y | 1 |
| Wang, Y | 1 |
| Zhang, Y | 1 |
| Liu, Q | 1 |
| Dammer, EB | 1 |
| Fallini, C | 1 |
| Gozal, YM | 1 |
| Duong, DM | 1 |
| Rossoll, W | 1 |
| Xu, P | 1 |
| Lah, JJ | 1 |
| Levey, AI | 1 |
| Peng, J | 1 |
| Bassell, GJ | 1 |
| Seyfried, NT | 1 |
2 other studies available for glycine and TDP-43 Proteinopathies
| Article | Year |
|---|---|
High glycine content in TDP-43: a potential culprit in limbic-predominant age-related TDP-43 encephalopathy.
Topics: Age Factors; Aged, 80 and over; Amino Acid Sequence; Brain; DNA-Binding Proteins; Glycine; Humans; P | 2020 |
Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination.
Topics: Amino Acid Motifs; Animals; Arginine; Blotting, Western; Cell Nucleus; Cytoplasm; DNA-Binding Protei | 2012 |