glycine has been researched along with Primary Graft Dysfunction in 1 studies
Primary Graft Dysfunction: A form of ischemia-reperfusion injury occurring in the early period following transplantation. Significant pathophysiological changes in MITOCHONDRIA are the main cause of the dysfunction. It is most often seen in the transplanted lung, liver, or kidney and can lead to GRAFT REJECTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In porcine NHBD-LTx, we previously reported a 50% risk of PNF and toxic bile formation in grafts exposed to > or =30' warm ischemia (WI)." | 1.35 | Multifactorial biological modulation of warm ischemia reperfusion injury in liver transplantation from non-heart-beating donors eliminates primary nonfunction and reduces bile salt toxicity. ( Balligand, E; Buurman, W; Deckx, H; Derveaux, K; Heedfeld, V; Hoekstra, H; Libbrecht, L; Liu, Q; Monbaliu, D; Parkkinen, J; Pirenne, J; Porte, RJ; Vaahtera, L; van Pelt, J; Vekemans, K; Wylin, T; Zeegers, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Monbaliu, D | 1 |
| Vekemans, K | 1 |
| Hoekstra, H | 1 |
| Vaahtera, L | 1 |
| Libbrecht, L | 1 |
| Derveaux, K | 1 |
| Parkkinen, J | 1 |
| Liu, Q | 1 |
| Heedfeld, V | 1 |
| Wylin, T | 1 |
| Deckx, H | 1 |
| Zeegers, M | 1 |
| Balligand, E | 1 |
| Buurman, W | 1 |
| van Pelt, J | 1 |
| Porte, RJ | 1 |
| Pirenne, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL): a First-in-men Study[NCT01886443] | Phase 1 | 10 participants (Actual) | Interventional | 2013-08-31 | Completed | ||
| Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL): a First-in-men Study[NCT02251041] | Phase 2 | 72 participants (Actual) | Interventional | 2014-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for glycine and Primary Graft Dysfunction