Page last updated: 2024-10-18

glycine and Pancreatitis

glycine has been researched along with Pancreatitis in 20 studies

Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.

Research Excerpts

ExcerptRelevanceReference
"Glycine administration resulted in a noticeable improvement of pathomorphological alterations in AP, such as a reduction of necrosis, inflammatory infiltrates and cytoplasmic vacuoles in cerulein pancreatitis."7.77Prophylactic glycine administration attenuates pancreatic damage and inflammation in experimental acute pancreatitis. ( Aghdassi, AA; Bergmann, F; Büchler, MW; Ceyhan, GO; Demir, IE; Friess, H; Günther, A; Kern, M; Lerch, MM; Mayerle, J; Schemmer, P; Timm, AK, 2011)
"The present study investigated whether chemokines are involved in hydrogen sulfide (H2S)-associated pathogenesis of acute pancreatitis and associated lung injury."7.74Inhibition of hydrogen sulfide synthesis attenuates chemokine production and protects mice against acute pancreatitis and associated lung injury. ( Bhatia, M; Moore, PK; Tamizhselvi, R, 2008)
"The incidence of acute pancreatitis has been rising worldwide in the past few decades."5.38Potential of sivelestat in protection against severe acute pancreatitis-associated lung injury in rats. ( Chen, L; Tang, AM; Wang, HH; Zhou, MT, 2012)
"Acute pancreatitis was induced in mice by 10 hourly intraperitoneal injections of caerulein (50 (g/kg)."5.35Pro-inflammatory effects of hydrogen sulphide on substance P in caerulein-induced acute pancreatitis. ( Bhatia, M; Moochhala, SM; Ng, SW; Sidhapuriwala, JN; Tamizhselvi, R, 2008)
"Hydrogen sulfide (H2S) is a naturally occurring gas with potent vasodilator activity."5.33Role of hydrogen sulfide in acute pancreatitis and associated lung injury. ( Bhatia, M; Fu, D; Lau, HY; Moochhala, SM; Moore, PK; Wong, FL, 2005)
"Glycine administration resulted in a noticeable improvement of pathomorphological alterations in AP, such as a reduction of necrosis, inflammatory infiltrates and cytoplasmic vacuoles in cerulein pancreatitis."3.77Prophylactic glycine administration attenuates pancreatic damage and inflammation in experimental acute pancreatitis. ( Aghdassi, AA; Bergmann, F; Büchler, MW; Ceyhan, GO; Demir, IE; Friess, H; Günther, A; Kern, M; Lerch, MM; Mayerle, J; Schemmer, P; Timm, AK, 2011)
"The present study investigated whether chemokines are involved in hydrogen sulfide (H2S)-associated pathogenesis of acute pancreatitis and associated lung injury."3.74Inhibition of hydrogen sulfide synthesis attenuates chemokine production and protects mice against acute pancreatitis and associated lung injury. ( Bhatia, M; Moore, PK; Tamizhselvi, R, 2008)
" In order to elucidate the significance of GAA synthesis in the pancreas, the author measured serum concentration of GAA, creatine, and the renal and pancreatic GAT activity in control, streptozotocin (STZ)-induced diabetic, insulin-treated diabetic, and ethionine-induced acute pancreatitis rats."3.67[Study of impaired metabolism of guanidinoacetic acid in uremia--the compensatory role of the pancreas in guanidinoacetic acid synthesis]. ( Hirata, M, 1989)
"The incidence of acute pancreatitis has been rising worldwide in the past few decades."1.38Potential of sivelestat in protection against severe acute pancreatitis-associated lung injury in rats. ( Chen, L; Tang, AM; Wang, HH; Zhou, MT, 2012)
"Acute pancreatitis was induced in mice by 10 hourly intraperitoneal injections of caerulein (50 (g/kg)."1.35Pro-inflammatory effects of hydrogen sulphide on substance P in caerulein-induced acute pancreatitis. ( Bhatia, M; Moochhala, SM; Ng, SW; Sidhapuriwala, JN; Tamizhselvi, R, 2008)
"Hydrogen sulfide (H2S) is a naturally occurring gas with potent vasodilator activity."1.33Role of hydrogen sulfide in acute pancreatitis and associated lung injury. ( Bhatia, M; Fu, D; Lau, HY; Moochhala, SM; Moore, PK; Wong, FL, 2005)
"Lung hemorrhage was seen in the animals with pancreatitis untreated with ONO-5046 24 hr following the first cerulein injection."1.29Neutrophil elastase inhibitor (ONO-5046) prevents lung hemorrhage induced by lipopolysaccharide in rat model of cerulein pancreatitis. ( Guo, L; Ikei, S; Ogawa, M; Sugita, H; Yamaguchi, Y, 1995)
"Acute pancreatitis is a dreaded complication of biliary calculus disease, and several radiographic signs have been reported in association with this condition."1.28The scintigraphic "duodenal cut off sign" in acute pancreatitis. ( Alexander, HG; Buckner, AB; Shanley, DJ, 1991)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19904 (20.00)18.7374
1990's5 (25.00)18.2507
2000's6 (30.00)29.6817
2010's5 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, H1
Wang, S1
Tang, A1
Gong, H1
Ma, P1
Chen, L2
Ji, L1
Li, L1
Qu, F1
Zhang, G1
Wang, Y1
Bai, X1
Pan, S1
Xue, D1
Wang, G1
Sun, B1
Moon, JM1
Chun, BJ1
Ceyhan, GO1
Timm, AK1
Bergmann, F1
Günther, A1
Aghdassi, AA1
Demir, IE1
Mayerle, J1
Kern, M1
Lerch, MM1
Büchler, MW1
Friess, H1
Schemmer, P1
Wang, HH1
Tang, AM1
Zhou, MT1
Bhatia, M3
Wong, FL1
Fu, D1
Lau, HY1
Moochhala, SM2
Moore, PK2
Anderson, S1
Shah, NP1
Zajick, D1
Cross, M1
Oates, ME1
Gao, HK1
Zhou, ZG1
Li, Y1
Chen, YQ1
Hsiao, CT1
Lin, LJ1
Hsiao, KY1
Chou, MH1
Hsiao, SH1
Sidhapuriwala, JN1
Ng, SW1
Tamizhselvi, R2
Guo, L1
Yamaguchi, Y1
Ikei, S1
Sugita, H1
Ogawa, M1
Bruin, T1
Tuzgöl, S1
van Diermen, DE1
Hoogerbrugge-van der Linden, N1
Brunzell, JD1
Hayden, MR1
Kastelein, JJ1
Imamura, M1
Mikami, Y1
Takahashi, H1
Yamauchi, H1
Hino, M1
Nagatsu, T1
Kakumu, S1
Okuyama, S1
Yoshii, Y1
Nagatsu, I1
Shih, WJ1
Marsano, L1
Shanley, DJ1
Buckner, AB1
Alexander, HG1
Hirata, M1
Bergström, K1
Hellström, K1
Kallner, M1
Lundh, G1
Pedersen, L1
Arnfred, T1
Thaysen, EH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intermittent Fasting as a Primary Means for Improving Quality of Life for Acute and Chronic Pancreatitis[NCT04760847]64 participants (Anticipated)Interventional2023-12-07Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

20 other studies available for glycine and Pancreatitis

ArticleYear
Combined effects of sivelestat and resveratrol on severe acute pancreatitis-associated lung injury in rats.
    Experimental lung research, 2014, Volume: 40, Issue:6

    Topics: Acute Disease; Amylases; Animals; Arterial Pressure; Bronchoalveolar Lavage Fluid; Glycine; Interleu

2014
Hydrogen sulphide exacerbates acute pancreatitis by over-activating autophagy via AMPK/mTOR pathway.
    Journal of cellular and molecular medicine, 2016, Volume: 20, Issue:12

    Topics: Alkynes; AMP-Activated Protein Kinases; Animals; Autophagy; Cell Line; Disease Progression; Glycine;

2016
Predicting acute complicated glyphosate intoxication in the emergency department.
    Clinical toxicology (Philadelphia, Pa.), 2010, Volume: 48, Issue:7

    Topics: Acute Disease; Adult; Age Factors; Aged; Alanine Transaminase; Emergency Service, Hospital; Female;

2010
Prophylactic glycine administration attenuates pancreatic damage and inflammation in experimental acute pancreatitis.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2011, Volume: 11, Issue:1

    Topics: Animals; Ceruletide; Chemoprevention; Cytokines; Disease Models, Animal; Enzymes; Glycine; Glycine A

2011
Potential of sivelestat in protection against severe acute pancreatitis-associated lung injury in rats.
    Experimental lung research, 2012, Volume: 38, Issue:9-10

    Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Glycine; Lung; Lung Injury; Male; Pan

2012
Role of hydrogen sulfide in acute pancreatitis and associated lung injury.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:6

    Topics: Acute Disease; Alkynes; Amylases; Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; C

2005
A positional maneuver to augment conventional cholescintigraphy in the evaluation of acute acalculous cholecystitis.
    Clinical nuclear medicine, 2006, Volume: 31, Issue:7

    Topics: Abdominal Pain; Acalculous Cholecystitis; Acute Disease; Aniline Compounds; Fever; Gallbladder; Glyc

2006
Toll-like receptor 4 Asp299Gly polymorphism is associated with an increased risk of pancreatic necrotic infection in acute pancreatitis: a study in the Chinese population.
    Pancreas, 2007, Volume: 34, Issue:3

    Topics: Adult; Amino Acid Substitution; APACHE; Aspartic Acid; Bacterial Infections; China; Female; Gene Fre

2007
Acute pancreatitis caused by severe glyphosate-surfactant oral intoxication.
    The American journal of emergency medicine, 2008, Volume: 26, Issue:3

    Topics: Acute Disease; Aged, 80 and over; Glycine; Glyphosate; Herbicides; Humans; Male; Pancreatitis; Paren

2008
Pro-inflammatory effects of hydrogen sulphide on substance P in caerulein-induced acute pancreatitis.
    Journal of cellular and molecular medicine, 2008, Volume: 12, Issue:2

    Topics: Acute Disease; Alkynes; Animals; Ceruletide; Cystathionine beta-Synthase; Glycine; Hydrogen Sulfide;

2008
Inhibition of hydrogen sulfide synthesis attenuates chemokine production and protects mice against acute pancreatitis and associated lung injury.
    Pancreas, 2008, Volume: 36, Issue:4

    Topics: Acute Disease; Alkynes; Animals; Ceruletide; Chemokine CCL5; Chemokines; Cystathionine gamma-Lyase;

2008
Neutrophil elastase inhibitor (ONO-5046) prevents lung hemorrhage induced by lipopolysaccharide in rat model of cerulein pancreatitis.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:10

    Topics: Animals; Ceruletide; Disease Models, Animal; Drug Evaluation, Preclinical; Glycine; Hemorrhage; Leuk

1995
Recurrent pancreatitis and chylomicronemia in an extended Dutch kindred is caused by a Gly154-->Ser substitution in lipoprotein lipase.
    Journal of lipid research, 1993, Volume: 34, Issue:12

    Topics: Adult; Base Sequence; Cell Line; Chylomicrons; DNA; Glycine; Humans; Lipoprotein Lipase; Male; Molec

1993
Effect of a specific synthetic inhibitor of neutrophil elastase (ONO-5046) on the course of acute hemorrhagic pancreatitis in dogs.
    Journal of hepato-biliary-pancreatic surgery, 1998, Volume: 5, Issue:4

    Topics: alpha-Macroglobulins; Amylases; Animals; Blood Pressure; Calcium; Disease Models, Animal; Dogs; Glyc

1998
Glycylprolyl beta-naphthylamidase activity in human serum.
    Clinica chimica acta; international journal of clinical chemistry, 1975, Jul-09, Volume: 62, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Alanine Transaminase; Aspartate Aminotransferas

1975
Cholescintigraphic demonstration of transient and functional common bile duct obstruction in a patient with acute pancreatitis.
    Bildgebung = Imaging, 1992, Volume: 59, Issue:1

    Topics: Acute Disease; Aged; Aniline Compounds; Cholestasis, Extrahepatic; Common Bile Duct Diseases; Diagno

1992
The scintigraphic "duodenal cut off sign" in acute pancreatitis.
    Clinical nuclear medicine, 1991, Volume: 16, Issue:4

    Topics: Acute Disease; Adult; Aniline Compounds; Duodenum; Female; Glycine; Humans; Imino Acids; Organotechn

1991
[Study of impaired metabolism of guanidinoacetic acid in uremia--the compensatory role of the pancreas in guanidinoacetic acid synthesis].
    Nihon Jinzo Gakkai shi, 1989, Volume: 31, Issue:9

    Topics: Acute Disease; Animals; Diabetes Mellitus, Experimental; Ethionine; Glycine; Insulin; Male; Pancreas

1989
Familial pancreatitis associated with hyperglycinuria.
    Scandinavian journal of gastroenterology, 1973, Volume: 8, Issue:3

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Amylases; Child; Female; Glycine; Humans;

1973
Rapid screening of increased bile acid deconjugation and bile acid malabsorption by means of the glycine-l-(14C) cholylglycine assay.
    Scandinavian journal of gastroenterology, 1973, Volume: 8, Issue:7

    Topics: Achlorhydria; Adult; Aged; Bile Acids and Salts; Carbon Radioisotopes; Chronic Disease; Colitis; Cro

1973