glycine and Nutritional Disorders studies

Research Excerpts

Excerpt	Relevance	Reference
"In rats fed 18% protein diet, administration of endosulfan (2mg/kg body weight daily for 7 days) significantly decreased the brush border sialic acid and increased the hexoses contents."	3.71	Effects of endosulfan on intestinal functions in protein-malnourished rats. ( Bansal, RC; Labana, S; Mahmood, A, 2001)
"Urea hydrolysis was calculated from the 15N enrichment of urinary urea, and where possible, lysine, alanine, glycine and histidine were isolated from urine by preparative ion-exchange chromatography for measurement of 15N enrichment."	1.31	The transfer of 15N from urea to lysine in the human infant. ( Ah-Sing, E; Badaloo, A; Boyne, M; Forrester, T; Gibson, N; Jackson, A; Millward, DJ; Persaud, C; Reade, M; Yeboah, N, 2000)
"[15N]Glycine was used as the tracer with a prime to infusion ratio of 1300 to 3300 min and a continuous-infusion rate of 0."	1.27	Tracer priming in human protein turnover studies with [15N]glycine. ( Brennan, MF; Daly, J; Horowitz, GD; Jeevanandam, M; Lowry, SF; Mihranian, MH; Rose, D, 1985)
"This study suggests that some malignant tumors can increase whole body protein synthesis and turnover in both the malnourished and fed state."	1.26	Whole body protein synthesis and turnover in normal man and malnourished patients with and without known cancer. ( Brennan, MF; Norton, JA; Stein, TP, 1981)
" Both free lysine and glycyl-L-lysine were well absorbed in the normal subject."	1.25	Dipeptide absorption in cystinuria. ( Hellier, MD; Holdsworth, CD; Perrett, D, 1970)
" The presence of glucose and galactose produced a significant impairment (up to 50%) in the rate of absorption of glycine."	1.25	Impairment of glycine absorption by glucose and galactose in man. ( Cook, GC, 1971)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (71.43)	18.7374
1990's	5 (14.29)	18.2507
2000's	5 (14.29)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
de Souza, KB	1
Feoli, AM	1
Krüger, AH	1
de Souza, MR	1
Perry, CT	1
Rotta, LN	1
Souza, DO	1
Perry, ML	1
Lima, NL	1
Soares, AM	1
Mota, RM	1
Monteiro, HS	1
Guerrant, RL	1
Lima, AA	1
Norton, JA	1
Stein, TP	1
Brennan, MF	2
Pathak, RM	1
Dudeja, PK	1
Ansari, S	1
Mahmood, A	2
Soares, MJ	2
Piers, LS	2
Shetty, PS	2
Jackson, AA	4
Waterlow, JC	3
Stroud, MA	1
Persaud, C	2
Forrester, T	2
Millward, DJ	1
Ah-Sing, E	1
Yeboah, N	1
Gibson, N	1
Badaloo, A	1
Boyne, M	1
Reade, M	1
Jackson, A	1
Dichi, JB	1
Dichi, I	1
Maio, R	1
Correa, CR	1
Angeleli, AY	1
Bicudo, MH	1
Rezende, TA	1
Burini, RC	1
Labana, S	1
Bansal, RC	1
Wapnir, RA	1
Lifshitz, F	1
Kopple, JD	1
Swendseid, ME	1
Hibbard, ED	1
Kenna, AP	1
Mestyán, J	2
Soltész, G	2
Schultz, K	1
Horváth, M	1
Hsu, JM	2
Anthony, WL	2
Rider, AA	1
Mishra, OP	1
Shankar, R	1
Robinson, S	1
Sharma, SK	1
Selvamurthy, W	1
Maheshwari, MC	1
Singh, TP	1
Rathbun, WE	1
Druse, MJ	1
Jeevanandam, M	1
Horowitz, GD	1
Rose, D	1
Mihranian, MH	1
Daly, J	1
Lowry, SF	1
Cook, GC	3
James, WP	1
Singh, PI	1
Sood, SC	1
Saini, AS	1
Pérès, GE	1
Cier, JF	1
Pérès, G	1
Harper, AE	1
Benevenga, NJ	1
Wohlhueter, RM	1
Simmons, WK	1
Kumar, V	1
Chase, HP	1
Fekete, M	1
Járai, I	1
Sulyok, E	1
Imhof, S	1
Arroyave, G	1
Hellier, MD	1
Perrett, D	1
Holdsworth, CD	1
Olson, RE	1
Bazzano, G	1
D'Ella, JA	1
Kirsch, RE	1
Saunders, SJ	1
Brock, JF	1

Trial			Phase	Enrollment	Study Type	Start Date	Status
Intervention and Mechanisms of Alanyl-Glutamine for Inflammation, Nutrition, and Enteropathy (IMAGINE)[NCT01832636]			Phase 3	112 participants (Actual)	Interventional	2013-10-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Protein and amino acid metabolism in uremic patients undergoing maintenance hemodialysis. Kidney international. Supplement, 1975, Issue:2 Topics: Adult; Amino Acids; Blood Urea Nitrogen; Body Weight; Dietary Proteins; Glycine; Humans; Male; Middl	1975
Protein synthesis and breakdown and amino acid catabolism in protein-calorie malnutrition. The Proceedings of the Nutrition Society, 1972, Volume: 31, Issue:2 Topics: Amino Acids; Animals; Apoproteins; Carbon Isotopes; Child; Glycine; Growth; Humans; Infant; Kwashior	1972
Effects of ingestion of disproportionate amounts of amino acids. Physiological reviews, 1970, Volume: 50, Issue:3 Topics: Adaptation, Physiological; Age Factors; Amino Acids; Ammonia; Animals; Cystine; Deficiency Diseases;	1970
The plasma amino acid ratio as an indicator of the protein nutrition status: a review of recent work. Bulletin of the World Health Organization, 1970, Volume: 42, Issue:3 Topics: Amino Acids; Animals; Child; Child Nutritional Physiological Phenomena; Child, Preschool; Chromatogr	1970

Article	Year
Effects of undernutrition on glycine metabolism in the cerebellum of rats. Annals of nutrition & metabolism, 2004, Volume: 48, Issue:4 Topics: Aging; Animals; Carbon Radioisotopes; Cerebellum; Dietary Proteins; Female; Glycine; Litter Size; Me	2004
Whole body protein synthesis and turnover in normal man and malnourished patients with and without known cancer. Annals of surgery, 1981, Volume: 194, Issue:2 Topics: Adult; Aged; Body Weight; Fasting; Female; Glycine; Humans; Male; Middle Aged; Neoplasms; Nitrogen I	1981
Alterations in intestinal function in response to thyroxine and cortisone administration in undernourished rats. Annals of nutrition & metabolism, 1982, Volume: 26, Issue:5 Topics: Animal Nutritional Physiological Phenomena; Animals; Cortisone; Glucose; Glycine; Intestinal Absorpt	1982
Whole body protein turnover in chronically undernourished individuals. Clinical science (London, England : 1979), 1994, Volume: 86, Issue:4 Topics: Adolescent; Adult; Basal Metabolism; Body Composition; Energy Intake; Glycine; Humans; Male; Nutriti	1994
Protein turnover rates of two human subjects during an unassisted crossing of Antarctica. The British journal of nutrition, 1996, Volume: 76, Issue:2 Topics: Adult; Antarctic Regions; Cold Temperature; Diet; Energy Metabolism; Glycine; Humans; Male; Middle A	1996
Urinary excretion of 5-L-oxoproline (pyroglutamic acid) is increased during recovery from severe childhood malnutrition and responds to supplemental glycine. The Journal of nutrition, 1996, Volume: 126, Issue:11 Topics: Aging; Body Weight; Child, Preschool; Female; Food, Fortified; Glutathione; Glycine; Growth; Humans;	1996
The transfer of 15N from urea to lysine in the human infant. The British journal of nutrition, 2000, Volume: 83, Issue:5 Topics: Alanine; Child, Preschool; Dietary Proteins; Glycine; Histidine; Humans; Hydrolysis; Infant; Lysine;	2000
Whole-body protein turnover in malnourished patients with child class B and C cirrhosis on diets low to high in protein energy. Nutrition (Burbank, Los Angeles County, Calif.), 2001, Volume: 17, Issue:3 Topics: Adult; Ammonia; Case-Control Studies; Dietary Proteins; Energy Intake; Fasting; Glycine; Humans; Liv	2001
Effects of endosulfan on intestinal functions in protein-malnourished rats. Indian journal of experimental biology, 2001, Volume: 39, Issue:10 Topics: Administration, Oral; Animals; Body Weight; Calcium; Cell Membrane; Dietary Proteins; Endosulfan; Gl	2001
Fasting-induced hypoglycemia in experimentally malnourished rats. The Journal of nutrition, 1977, Volume: 107, Issue:3 Topics: Adaptation, Physiological; Alanine; Aminobutyrates; Animals; Brain Chemistry; Disease Models, Animal	1977
Valine/glycine ratio in newborn infants. Biology of the neonate, 1975, Volume: 27, Issue:1-2 Topics: Birth Weight; Female; Fetal Blood; Glycine; Humans; Infant, Newborn; Infant, Premature; Maternal-Fet	1975
Hyperaminoacidemia due to the accumulation of gluconeogenic amino acid precursors in hypoglycemic small-for-gestational age infants. The Journal of pediatrics, 1975, Volume: 87, Issue:3 Topics: Alanine; Amino Acids; Birth Weight; Female; Gestational Age; Gluconeogenesis; Glycine; Humans; Hypog	1975
Free amino acids in plasma and tissue of rats born to underfed dams. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 148, Issue:4 Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Arginine; Body Weight; Female; Glutamates; Glycine;	1975
Glycine transport in isolated cerebral tissue during malnourishment and its response to neurotropic drugs. Indian journal of biochemistry & biophysics, 1975, Volume: 12, Issue:3 Topics: Animals; Cerebral Cortex; Depression, Chemical; Glycine; In Vitro Techniques; Nutrition Disorders; P	1975
Basal metabolic rate, body composition and whole-body protein turnover in Indian men with differing nutritional status. Clinical science (London, England : 1979), 1991, Volume: 81, Issue:3 Topics: Adult; Basal Metabolism; Body Composition; Glycine; Humans; Male; Nitrogen; Nutrition Disorders; Nut	1991
Kainic acid induced epileptogenesis in developing normal & undernourished rats--a computerised EEG analysis. The Indian journal of medical research, 1990, Volume: 92 Topics: Age Factors; Animals; Cerebellum; Electroencephalography; Glycine; Hippocampus; Kainic Acid; Nutriti	1990
Maternal undernutrition during lactation: effect on amino acids in brain regions of offspring. Journal of neurochemistry, 1985, Volume: 45, Issue:6 Topics: Amino Acids; Animals; Aspartic Acid; Body Weight; Brain Chemistry; Corpus Striatum; Female; gamma-Am	1985
Tracer priming in human protein turnover studies with [15N]glycine. Biochemical medicine, 1985, Volume: 34, Issue:2 Topics: Ammonia; Glycine; Humans; Infusions, Parenteral; Injections, Intravenous; Kinetics; Mathematics; Met	1985
Relation of absorption rates of glucose, glycine and glycylglycine to serum globulin concentrations in man in vivo. East African medical journal, 1974, Volume: 51, Issue:1 Topics: Dietary Carbohydrates; Dipeptides; gamma-Globulins; Glucose; Glycine; Humans; Intestinal Absorption;	1974
Jejunal absorption rates of glucose, glycine and glycylglycine in Zambian African adults with malnutrition. The British journal of nutrition, 1974, Volume: 32, Issue:3 Topics: Adult; Aged; Biopsy; Dipeptides; Female; gamma-Globulins; Glucose; Glycine; Glycylglycine; Humans; I	1974
Plasma nonessential to essential amino acid ratio in marasmus. The American journal of clinical nutrition, 1973, Volume: 26, Issue:5 Topics: Amino Acids; Blood Proteins; Child; Child Nutritional Physiological Phenomena; Chromatography, Paper	1973
[Nutritional significance of the effect exerted by a elevated sodium diet on the intestinal absorption of glycine by the rat]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1973, Volume: 167, Issue:8 Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Diet; Emaciation; Glycine; Hyperto	1973
Undernutrition and intestinal dipeptide hydrolase activity in the rat. The Journal of nutrition, 1971, Volume: 101, Issue:11 Topics: Age Factors; Alkaline Phosphatase; Animals; Diarrhea, Infantile; Dipeptidases; Female; Glycine; Glyc	1971
The postnatal changes in the circulating free amino acid pool in the newborn infant. II. The plasma amino acid ratio in intrauterine malnutrition (small for dates' full-term, preterm and twin infants). Biologia neonatorum. Neo-natal studies, 1969, Volume: 14, Issue:3 Topics: Amino Acids; Birth Weight; Chromatography, Paper; Female; Fetal Diseases; Gestational Age; Glutamine	1969
Comparative sensitivity of specific amino acid ratios versus "essential to nonessential" amino acid ratio. The American journal of clinical nutrition, 1970, Volume: 23, Issue:6 Topics: Adult; Amino Acids; Child; Cystine; Diet; Female; Glycine; Humans; Isoleucine; Kwashiorkor; Leucine;	1970
Dipeptide absorption in cystinuria. British medical journal, 1970, Dec-26, Volume: 4, Issue:5738 Topics: Cystinuria; Dipeptides; Glycine; Humans; Intestinal Absorption; Lysine; Malabsorption Syndromes; Mal	1970
The effects of large amounts of glutamic acid upon serum lipids and sterol metabolism in man. Transactions of the Association of American Physicians, 1970, Volume: 83 Topics: Adult; Amino Acids; Ammonia; Anticholesteremic Agents; Cholesterol; Chromatography, Gas; Dietary Fat	1970
Impairment of glycine absorption by glucose and galactose in man. The Journal of physiology, 1971, Volume: 217, Issue:1 Topics: Adolescent; Adult; Aged; Amino Acids; Dietary Carbohydrates; Female; Galactose; Gastroenteritis; Glu	1971
Impairment of cystine-35S incorporation into skin protein by zinc-deficient rats. The Journal of nutrition, 1971, Volume: 101, Issue:4 Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Bone and Bones; Carbon Dioxide; Ca	1971
Amino acid transport in experimental protein-calorie malnutrition. The American journal of clinical nutrition, 1968, Volume: 21, Issue:11 Topics: Animals; Biological Transport; Carbon Isotopes; Dietary Proteins; Glycine; In Vitro Techniques; Inte	1968

glycine and Nutritional Disorders

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