glycine has been researched along with Neuralgia in 25 studies
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, NFPS (1 mg/kg) produced antiallodynia after four days of treatment." | 1.62 | Pharmacological Evidence on Augmented Antiallodynia Following Systemic Co-Treatment with GlyT-1 and GlyT-2 Inhibitors in Rat Neuropathic Pain Model. ( Al-Khrasani, M; Balogh, M; Barsi, S; Benyhe, S; Galambos, AR; Harsing, LG; Karádi, DÁ; Király, K; Köles, L; Lakatos, PP; Mohammadzadeh, A; Riba, P; Szökő, É; Tábi, T; Zádor, F; Zádori, ZS, 2021) |
| "MCS reversed the hyperalgesia induced by peripheral neuropathy in the rats with chronic sciatic nerve constriction and induced a significant increase in the glycine and GABA levels in the PAG in comparison with the naive and sham-treated rats." | 1.51 | Neurochemical effects of motor cortex stimulation in the periaqueductal gray during neuropathic pain. ( Antunes, GF; Assis, DV; Auada, AVV; de Andrade, EM; Fonoff, ET; Gouveia, FV; Lebrun, I; Lopes, PSS; Martinez, RCR; Pagano, RL, 2019) |
| "Treatment with SR9009 also blocked tumor necrosis factor-induced IL-1β mRNA, IL-6 mRNA and MMP-9 mRNA." | 1.51 | Stimulation of nuclear receptor REV-ERBs suppresses production of pronociceptive molecules in cultured spinal astrocytes and ameliorates mechanical hypersensitivity of inflammatory and neuropathic pain of mice. ( Hisaoka-Nakashima, K; Kodama, K; Morioka, N; Nakamura, Y; Nakata, Y; Saeki, M; Tomori, M; Yoshikawa, K; Zhang, FF, 2019) |
| "Neuropathic pain is an integral component of several chronic pain conditions and poses a major health problem worldwide." | 1.46 | Therapeutic potential for leukocyte elastase in chronic pain states harboring a neuropathic component. ( Bali, KK; Kuner, R, 2017) |
| "Diabetic neuropathic pain (DNP) is a common clinical problem, and the mechanisms underlying the onset and progression of this complication are poorly understood." | 1.43 | Reduction of spinal glycine receptor-mediated miniature inhibitory postsynaptic currents in streptozotocin-induced diabetic neuropathic pain. ( Chiu, YC; Liao, WT; Lin, CR; Liu, CK; Wu, CH, 2016) |
| "Neuropathic pain is a serious chronic disorder caused by lesion or dysfunction in the nervous systems." | 1.36 | Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de ( Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K, 2010) |
| "In vivo testing in a rodent model of neuropathic pain indicated one amino acid significantly and dose-dependently decreased mechanical allodynia." | 1.36 | A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity. ( Abell, AD; Avery, TD; Bräuner-Osborne, H; Hutchinson, MR; Irvine, RJ; Kvist, T; Mathiesen, JM; Nielsen, B; Pedersen, DS; Stanley, NJ; Taylor, DK; Tiekink, ER, 2010) |
| "Management of neuropathic pain remains problematic; however, cell therapy to treat the effects of pain on the sensory system after spinal cord injury (SCI) could be a useful approach." | 1.35 | Clinical feasibility for cell therapy using human neuronal cell line to treat neuropathic behavioral hypersensitivity following spinal cord injury in rats. ( Eaton, MJ; Wolfe, SQ, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 7 (28.00) | 29.6817 |
| 2010's | 12 (48.00) | 24.3611 |
| 2020's | 3 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, S | 1 |
| Nakata, E | 1 |
| Morita, A | 1 |
| Mizuno, K | 1 |
| Yamamura, K | 1 |
| Kato, A | 1 |
| Ohashi, K | 1 |
| Wang, J | 1 |
| Ding, Z | 1 |
| Xu, W | 1 |
| He, L | 1 |
| Huang, J | 1 |
| Zhang, C | 1 |
| Guo, Q | 1 |
| Zou, W | 1 |
| Narasimhan, M | 1 |
| Mahimainathan, L | 1 |
| Reddy, PH | 1 |
| Benamar, K | 1 |
| Mohammadzadeh, A | 2 |
| Lakatos, PP | 1 |
| Balogh, M | 2 |
| Zádor, F | 1 |
| Karádi, DÁ | 1 |
| Zádori, ZS | 2 |
| Király, K | 2 |
| Galambos, AR | 1 |
| Barsi, S | 2 |
| Riba, P | 1 |
| Benyhe, S | 1 |
| Köles, L | 2 |
| Tábi, T | 1 |
| Szökő, É | 1 |
| Harsing, LG | 2 |
| Al-Khrasani, M | 2 |
| Muley, MM | 1 |
| Krustev, E | 1 |
| Reid, AR | 1 |
| McDougall, JJ | 1 |
| Bali, KK | 1 |
| Kuner, R | 1 |
| Xie, JD | 1 |
| Chen, SR | 1 |
| Pan, HL | 1 |
| de Andrade, EM | 1 |
| Martinez, RCR | 1 |
| Pagano, RL | 1 |
| Lopes, PSS | 1 |
| Auada, AVV | 1 |
| Gouveia, FV | 1 |
| Antunes, GF | 1 |
| Assis, DV | 1 |
| Lebrun, I | 1 |
| Fonoff, ET | 1 |
| Morioka, N | 2 |
| Kodama, K | 1 |
| Tomori, M | 1 |
| Yoshikawa, K | 1 |
| Saeki, M | 1 |
| Nakamura, Y | 1 |
| Zhang, FF | 1 |
| Hisaoka-Nakashima, K | 1 |
| Nakata, Y | 1 |
| Hajnal, B | 1 |
| Chirila, AM | 1 |
| Brown, TE | 1 |
| Bishop, RA | 1 |
| Bellono, NW | 1 |
| Pucci, FG | 1 |
| Kauer, JA | 1 |
| Werdehausen, R | 1 |
| Mittnacht, S | 1 |
| Bee, LA | 1 |
| Minett, MS | 1 |
| Armbruster, A | 1 |
| Bauer, I | 1 |
| Wood, JN | 1 |
| Hermanns, H | 1 |
| Eulenburg, V | 1 |
| Chiu, YC | 1 |
| Liao, WT | 1 |
| Liu, CK | 1 |
| Wu, CH | 1 |
| Lin, CR | 1 |
| Eaton, MJ | 1 |
| Wolfe, SQ | 1 |
| Stanley, NJ | 1 |
| Hutchinson, MR | 1 |
| Kvist, T | 1 |
| Nielsen, B | 1 |
| Mathiesen, JM | 1 |
| Bräuner-Osborne, H | 1 |
| Avery, TD | 1 |
| Tiekink, ER | 1 |
| Pedersen, DS | 1 |
| Irvine, RJ | 1 |
| Abell, AD | 1 |
| Taylor, DK | 1 |
| Hossaini, M | 1 |
| Saraç, C | 1 |
| Jongen, JL | 1 |
| Holstege, JC | 1 |
| Atkinson, D | 1 |
| Beasley, M | 1 |
| Dryburgh, P | 1 |
| Lynch, JJ | 1 |
| Honore, P | 1 |
| Anderson, DJ | 1 |
| Bunnelle, WH | 1 |
| Mortell, KH | 1 |
| Zhong, C | 1 |
| Wade, CL | 1 |
| Zhu, CZ | 1 |
| Xu, H | 1 |
| Marsh, KC | 1 |
| Lee, CH | 1 |
| Jarvis, MF | 1 |
| Gopalakrishnan, M | 1 |
| Morita, K | 1 |
| Motoyama, N | 1 |
| Kitayama, T | 1 |
| Dohi, T | 1 |
| Quintero Wolfe, SC | 1 |
| Cumberbatch, N | 1 |
| Menendez, I | 1 |
| Martinez, M | 1 |
| Eaton, M | 1 |
| Simpson, RK | 2 |
| Gondo, M | 2 |
| Robertson, CS | 2 |
| Goodman, JC | 2 |
| Mertens, P | 1 |
| Ghaemmaghami, C | 1 |
| Bert, L | 1 |
| Perret-Liaudet, A | 1 |
| Sindou, M | 1 |
| Renaud, B | 1 |
| Quartaroli, M | 1 |
| Fasdelli, N | 1 |
| Bettelini, L | 1 |
| Maraia, G | 1 |
| Corsi, M | 1 |
| Dudgeon, JA | 1 |
| Marshall, WC | 1 |
| Peckham, CS | 1 |
2 reviews available for glycine and Neuralgia
| Article | Year |
|---|---|
Glycine transporter inhibitors: A new avenue for managing neuropathic pain.
Topics: Animals; Glycine; Glycine Plasma Membrane Transport Proteins; Humans; Hyperalgesia; Neuralgia; Neuro | 2019 |
Antinociceptive effects of glycine transporter inhibitors in neuropathic pain models in mice.
Topics: Analgesics; Animals; Brain-Derived Neurotrophic Factor; Chlorine; Disease Models, Animal; Glycine; G | 2007 |
1 trial available for glycine and Neuralgia
| Article | Year |
|---|---|
Rubella vaccine trials in adults and children. Comparison of three attenuated vaccines.
Topics: Adolescent; Adult; Age Factors; Animals; Antibodies; Antibody Formation; Body Temperature; Buffers; | 1969 |
22 other studies available for glycine and Neuralgia
| Article | Year |
|---|---|
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, | 2010 |
Botulinum toxin type A counteracts neuropathic pain by countering the increase of GlyT2 expression in the spinal cord of CCI rats.
Topics: Analgesics; Animals; Botulinum Toxins, Type A; Crush Injuries; Glycine; Glycine Plasma Membrane Tran | 2022 |
GPR18-NAGly system in periaqueductal gray and chronic neuropathic pain.
Topics: Animals; Arachidonic Acids; Chronic Pain; Glycine; Male; Neuralgia; Periaqueductal Gray; Rats; Rats, | 2020 |
Pharmacological Evidence on Augmented Antiallodynia Following Systemic Co-Treatment with GlyT-1 and GlyT-2 Inhibitors in Rat Neuropathic Pain Model.
Topics: Animals; Glycine; Glycine Plasma Membrane Transport Proteins; Hyperalgesia; Male; Motor Activity; Ne | 2021 |
Prophylactic inhibition of neutrophil elastase prevents the development of chronic neuropathic pain in osteoarthritic mice.
Topics: Animals; Chronic Pain; Glycine; Leukocyte Elastase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; | 2017 |
Therapeutic potential for leukocyte elastase in chronic pain states harboring a neuropathic component.
Topics: Analgesics; Animals; Cancer Pain; Chronic Pain; Cyclic S-Oxides; Disease Models, Animal; Female; Gly | 2017 |
Presynaptic mGluR5 receptor controls glutamatergic input through protein kinase C-NMDA receptors in paclitaxel-induced neuropathic pain.
Topics: Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Cells, Cultured; Evoked Potentials; Ex | 2017 |
Neurochemical effects of motor cortex stimulation in the periaqueductal gray during neuropathic pain.
Topics: Analgesia; Animals; Bicuculline; Deep Brain Stimulation; Efferent Pathways; GABA Antagonists; gamma- | 2019 |
Stimulation of nuclear receptor REV-ERBs suppresses production of pronociceptive molecules in cultured spinal astrocytes and ameliorates mechanical hypersensitivity of inflammatory and neuropathic pain of mice.
Topics: Animals; Astrocytes; Cytokines; Female; Glial Fibrillary Acidic Protein; Glycine; Hyperalgesia; Infl | 2019 |
Long-term potentiation of glycinergic synapses triggered by interleukin 1β.
Topics: Animals; Behavior, Animal; GABAergic Neurons; Glycine; Hyperalgesia; Interleukin-1beta; Interneurons | 2014 |
The lidocaine metabolite N-ethylglycine has antinociceptive effects in experimental inflammatory and neuropathic pain.
Topics: Analgesics; Animals; Disease Models, Animal; Freund's Adjuvant; Glutamic Acid; Glycine; Male; Membra | 2015 |
Reduction of spinal glycine receptor-mediated miniature inhibitory postsynaptic currents in streptozotocin-induced diabetic neuropathic pain.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycine; Inhibitory Postsynaptic P | 2016 |
Clinical feasibility for cell therapy using human neuronal cell line to treat neuropathic behavioral hypersensitivity following spinal cord injury in rats.
Topics: Animals; Behavior, Animal; Cell Line; Cell- and Tissue-Based Therapy; Excitatory Amino Acid Agonists | 2009 |
A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity.
Topics: Analgesics; Animals; CHO Cells; Cricetinae; Cricetulus; Cyclopropanes; Glycine; Hyperalgesia; Male; | 2010 |
Spinal glycinergic and GABAergic neurons expressing C-fos after capsaicin stimulation are increased in rats with contralateral neuropathic pain.
Topics: Animals; Capsaicin; Freund's Adjuvant; Functional Laterality; GABAergic Neurons; Glycine; Inflammati | 2011 |
Accidental subcutaneous copper salt injection: toxic effects and management.
Topics: Accidents, Occupational; Adult; Animal Husbandry; Copper; Debridement; Edetic Acid; Glycine; Humans; | 2004 |
(L)-Phenylglycine, but not necessarily other alpha2delta subunit voltage-gated calcium channel ligands, attenuates neuropathic pain in rats.
Topics: Analgesics; Animals; Brain; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Do | 2006 |
Ronald Tasker Award: Intrathecal transplantation of a human neuronal cell line for the treatment of neuropathic pain in a spinal cord injury model.
Topics: Animals; Carcinoma, Embryonal; Cell Line, Tumor; gamma-Aminobutyric Acid; Glycine; Injections, Spina | 2007 |
Reduction in the mechanonociceptive response by intrathecal administration of glycine and related compounds.
Topics: Animals; Cerebrospinal Fluid; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glycine; Glyci | 1996 |
Reduction in thermal hyperalgesia by intrathecal administration of glycine and related compounds.
Topics: Analgesia, Epidural; Animals; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Glyci | 1997 |
Amino acids in spinal dorsal horn of patients during surgery for neuropathic pain or spasticity.
Topics: Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Extracellular Space; Feasibility S | 2000 |
GV196771A, an NMDA receptor/glycine site antagonist, attenuates mechanical allodynia in neuropathic rats and reduces tolerance induced by morphine in mice.
Topics: Animals; Behavior, Animal; Binding Sites; Constriction, Pathologic; Disease Models, Animal; Dose-Res | 2001 |