Page last updated: 2024-10-18

glycine and Neoplasm Metastasis

glycine has been researched along with Neoplasm Metastasis in 23 studies

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"When three diazoacetyl-glycine derivatives, N-diazoacetyl-glycine amide (DGA), N-diazoacetyl-glycine hydrazide (DGI), and N-diazoacetyl-glycine ethyl ester (DGE), were tested against Lewis lung carcinoma in C57BL mice, DGA reduced sharply the number and weight of pulmonary metastases; the effects of DGI and DGE were less pronounced."3.65Antimetastatic effects of N-diazoacetyl-glycine derivatives in C57BL mice. ( Giraldi, T; Nisi, C; Sava, G, 1977)
"Ixazomib is a selective and reversible inhibitor of the proteasome, which has been mainly investigated in the treatment of multiple myeloma."2.87Ixazomib in combination with carboplatin in pretreated women with advanced triple-negative breast cancer, a phase I/II trial of the AGMT (AGMT MBC-10 trial). ( Balic, M; Bartsch, R; Burgstaller, S; Egle, D; Fuchs, D; Gampenrieder, SP; Greil, R; Melchardt, T; Mlineritsch, B; Petru, E; Petzer, A; Rinnerthaler, G; Rossmann, D; Rumpold, H; Singer, CF; Ulmer, H, 2018)
"Using 36 biopsies from patients with brain tumors [12 glioblastoma multiforme (GBM); 10 low-grade (LG), including 7 schwannoma and 3 pylocytic astrocytoma; 7 meningioma (MN); 7 brain metastases (MT), including 3 adenocarcinoma and 4 breast cancer] and 9 control biopsies from patients undergoing surgery for epilepsy, we tested the hypothesis that the presence of glycine may distinguish among these brain tumor types."1.36High-resolution magic angle spinning magnetic resonance spectroscopy detects glycine as a biomarker in brain tumors. ( Andronesi, OC; Black, PM; Mintzopoulos, D; Righi, V; Tzika, AA, 2010)
"Once positive the circulating tumor cells persisted in subsequent multiple blood samples."1.31K-ras mutational analysis of polyclonal colorectal cancers identifies uniclonal circulating tumor cells. ( Krygier, S; Luchtefeld, MA; Senagore, AJ; Thebo, JS, 2001)
"The putative metastasis suppressor genes, NME1(nm23-1) and NME2(nm23-2), were examined in a model system we developed to approximate the dissemination of melanoma from a primary skin tumor."1.29Differential expression and mutation of NME genes in autologous cultured human melanoma cells with different metastatic potentials. ( Backer, JM; Hamby, CV; Mendola, CE; Potla, L; Stafford, G, 1995)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199010 (43.48)18.7374
1990's4 (17.39)18.2507
2000's5 (21.74)29.6817
2010's4 (17.39)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rinnerthaler, G1
Gampenrieder, SP1
Petzer, A1
Burgstaller, S1
Fuchs, D1
Rossmann, D1
Balic, M1
Egle, D1
Rumpold, H1
Singer, CF1
Bartsch, R1
Petru, E1
Melchardt, T1
Ulmer, H1
Mlineritsch, B1
Greil, R1
Muqaku, B1
Eisinger, M1
Meier, SM1
Tahir, A1
Pukrop, T1
Haferkamp, S1
Slany, A1
Reichle, A1
Gerner, C1
Chatterjee, S1
Mookerjee, A1
Basu, JM1
Chakraborty, P1
Ganguly, A1
Adhikary, A1
Mukhopadhyay, D1
Ganguly, S1
Ganguli, S1
Banerjee, R1
Ashraf, M1
Biswas, J1
Das, PK1
Sa, G1
Chatterjee, M1
Das, T1
Choudhuri, SK1
Righi, V1
Andronesi, OC1
Mintzopoulos, D1
Black, PM1
Tzika, AA1
Rachagani, S1
Senapati, S1
Chakraborty, S1
Ponnusamy, MP1
Kumar, S1
Smith, LM1
Jain, M1
Batra, SK1
UNGER, RH1
LOCHNERJDE, V1
EISENTRAUT, AM1
HORKY, J1
PLACER, Z1
Wang, J1
Stockton, DW1
Ittmann, M1
Xiong, XB1
Mahmud, A1
Uludağ, H1
Lavasanifar, A1
Cardot-Bauters, C1
Leteurtre, E1
Leclerc, L1
Vantyghem, MC1
Do Cao, C1
Wemeau, JL1
d'Herbomez, M1
Carnaille, B1
Barbu, V1
Pinson, S1
Pigny, P1
Hamby, CV1
Mendola, CE1
Potla, L1
Stafford, G1
Backer, JM1
Pei, L1
Melmed, S1
Scheithauer, B1
Kovacs, K1
Prager, D1
Lozonschi, L1
Sunamura, M1
Kobari, M1
Egawa, S1
Ding, L1
Matsuno, S1
Thebo, JS1
Senagore, AJ1
Krygier, S1
Luchtefeld, MA1
Giraldi, T2
Guarino, AM1
Nisi, C2
Baldini, L1
Sava, G1
Guerinot, F1
Bohuon, C1
Saravis, CA1
Oh, SK1
Pusztaszeri, G1
Doos, W1
Zamcheck, N1
Isoai, A1
Ueno, Y1
Giga-Hama, Y1
Goto, H1
Kumagai, H1
Ward, HC1
Johnson, AW1
Halliday, D1
Sim, AJ1
Yancey, ST1
Laki, K1
Brunner, G1
Sommer, J1
Kattermann, R1
Weise, HJ1
Wiegandt, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ixazomib (MLN9708) in Combination With Carboplatin in Pretreated Women With Advanced Triple Negative Breast Cancer[NCT02993094]Phase 1/Phase 231 participants (Actual)Interventional2016-11-21Terminated (stopped due to Due to slow recruitment, the study had to be terminated prematurely.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for glycine and Neoplasm Metastasis

ArticleYear
Ixazomib in combination with carboplatin in pretreated women with advanced triple-negative breast cancer, a phase I/II trial of the AGMT (AGMT MBC-10 trial).
    BMC cancer, 2018, Nov-06, Volume: 18, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Austria; Boron Compounds; Bortezomib; C

2018

Other Studies

22 other studies available for glycine and Neoplasm Metastasis

ArticleYear
Multi-omics Analysis of Serum Samples Demonstrates Reprogramming of Organ Functions Via Systemic Calcium Mobilization and Platelet Activation in Metastatic Melanoma.
    Molecular & cellular proteomics : MCP, 2017, Volume: 16, Issue:1

    Topics: Asparagine; Biomarkers, Tumor; Blood Platelets; Cachexia; Calcium; Glycine; Humans; Melanoma; Metabo

2017
A novel copper chelate modulates tumor associated macrophages to promote anti-tumor response of T cells.
    PloS one, 2009, Sep-16, Volume: 4, Issue:9

    Topics: Animals; CD4-Positive T-Lymphocytes; Chelating Agents; Copper; Drug Resistance, Neoplasm; Glycine; I

2009
High-resolution magic angle spinning magnetic resonance spectroscopy detects glycine as a biomarker in brain tumors.
    International journal of oncology, 2010, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Biomarkers, Tumor; Brain Neoplasms; Glioblastoma; Glycine; Humans; Inositol; Magn

2010
Activated KrasG¹²D is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin.
    British journal of cancer, 2011, Mar-15, Volume: 104, Issue:6

    Topics: Adenocarcinoma; Amino Acid Substitution; Animals; Aspartic Acid; Cadherins; Down-Regulation; Gene Ex

2011
IDENTIFICATION OF INSULIN AND GLUGACON IN A BRONCHOGENIC METASTASIS.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: Carcinoma; Carcinoma, Bronchogenic; Chemical Phenomena; Chemistry; Cysteine; Electrophoresis; Glucag

1964
[DIAGNOSTIC SIGNIFICANCE OF SERUM PEPTIDASE DETERMINATION IN BLASTOMATOUS DISEASES].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1965, Volume: 46

    Topics: Blood; Clinical Enzyme Tests; Diagnosis, Differential; Endopeptidases; Glycine; Heart Failure; Human

1965
The fibroblast growth factor receptor-4 Arg388 allele is associated with prostate cancer initiation and progression.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Sep-15, Volume: 10, Issue:18 Pt 1

    Topics: Alleles; Arginine; Case-Control Studies; Cell Movement; Collagen; Disease Progression; DNA; DNA, Com

2004
Conjugation of arginine-glycine-aspartic acid peptides to poly(ethylene oxide)-b-poly(epsilon-caprolactone) micelles for enhanced intracellular drug delivery to metastatic tumor cells.
    Biomacromolecules, 2007, Volume: 8, Issue:3

    Topics: Aldehydes; Arginine; Aspartic Acid; Cell Line, Tumor; Drug Delivery Systems; Glycine; Humans; Lacton

2007
Does the RET variant G691S influence the features of sporadic medullary thyroid carcinoma?
    Clinical endocrinology, 2008, Volume: 69, Issue:3

    Topics: Adolescent; Adult; Age of Onset; Aged; Carcinoma, Medullary; Case-Control Studies; Female; Genetic V

2008
Differential expression and mutation of NME genes in autologous cultured human melanoma cells with different metastatic potentials.
    Biochemical and biophysical research communications, 1995, Jun-15, Volume: 211, Issue:2

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Clone Cells; DNA Primers; Gene Expression; G

1995
H-ras mutations in human pituitary carcinoma metastases.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 78, Issue:4

    Topics: Adenoma; Alanine; Arginine; Base Sequence; DNA, Neoplasm; Exons; Genes, p53; Genes, ras; Glycine; Hu

1994
Controlling tumor angiogenesis and metastasis of C26 murine colon adenocarcinoma by a new matrix metalloproteinase inhibitor, KB-R7785, in two tumor models.
    Cancer research, 1999, Mar-15, Volume: 59, Issue:6

    Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Glycine; Hydroxamic Acids; Lung Neoplasms; Male; Metallo

1999
K-ras mutational analysis of polyclonal colorectal cancers identifies uniclonal circulating tumor cells.
    The American surgeon, 2001, Volume: 67, Issue:8

    Topics: Aspartic Acid; Colorectal Neoplasms; Disease Progression; DNA Mutational Analysis; Genes, ras; Glyci

2001
Selective antimetastatic effects of N-diazoacetylglycine derivatives in mice.
    European journal of cancer, 1979, Volume: 15, Issue:4

    Topics: Animals; Azo Compounds; Drug Evaluation, Preclinical; Glycine; Lung Neoplasms; Mice; Neoplasm Metast

1979
Antimetastatic effects of N-diazoacetyl-glycine derivatives in C57BL mice.
    Journal of the National Cancer Institute, 1977, Volume: 58, Issue:4

    Topics: Animals; Azo Compounds; Glycine; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neop

1977
Glycine-N-methyltransferase levels in human breast cancer tissue.
    European journal of cancer, 1977, Volume: 13, Issue:11

    Topics: Breast Neoplasms; Female; Glycine; Humans; Methyltransferases; Neoplasm Metastasis

1977
Present status of the zinc glycinate marker (ZGM).
    Cancer, 1978, Volume: 42, Issue:3 Suppl

    Topics: Antigens, Neoplasm; Chromatography, Gel; Colonic Neoplasms; Glycine; Humans; Neoplasm Metastasis; Ne

1978
A novel Arg-Gly-Asp containing peptide specific for platelet aggregation and its effect on tumor metastasis: a possible mechanism of RGD peptide-mediated inhibition of tumor metastasis.
    Cancer letters, 1992, Aug-31, Volume: 65, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Arginine; Aspartic Acid; Carcinoma, Squamous Cell; Cell Adhesion;

1992
Elevated rates of whole body protein metabolism in patients with disseminated malignancy in the immediate postoperative period.
    The British journal of surgery, 1985, Volume: 72, Issue:12

    Topics: Aged; Female; Glycine; Humans; Male; Middle Aged; Neoplasm Metastasis; Nitrogen; Nitrogen Isotopes;

1985
Transglutaminase and tumor growth.
    Annals of the New York Academy of Sciences, 1972, Dec-08, Volume: 202

    Topics: Animals; Blood Coagulation; Cross Reactions; Dipeptides; Glutamine; Glycine; Glycosides; Guinea Pigs

1972
[On the behavior of the so-called leucine aminopeptidase (LAP) in the serum during the application of various substrates].
    Klinische Wochenschrift, 1968, May-15, Volume: 46, Issue:10

    Topics: Adolescent; Adult; Aged; Animals; Aspartate Aminotransferases; Biliary Tract Diseases; Cholestasis;

1968
[On a rare form of metastasizing carcinoids in association with excessive isolated glycinuria].
    Medizinische Klinik, 1963, Sep-06, Volume: 58, Issue:36

    Topics: Amino Acid Metabolism, Inborn Errors; Biopsy; Carcinoid Tumor; Female; Glycine; Humans; Iron; Liver

1963