Page last updated: 2024-10-18

glycine and Myoclonic Jerk

glycine has been researched along with Myoclonic Jerk in 27 studies

Research Excerpts

ExcerptRelevanceReference
"In mice, the ED(50) values for seizures following intraperitoneal injection were allylglycine 1."5.25Seizures induced by allylglycine, 3-mercaptopropionic acid and 4-deoxypyridoxine in mice and photosensitive baboons, and different modes of inhibition of cerebral glutamic acid decarboxylase. ( Horton, RW; Meldrum, BS, 1973)
" The patient presented with myoclonic jerks, apnea and encephalopathy three months after birth without satisfactory therapeutic response."3.75Atypical glycine encephalopathy in an extremely low birth weight infant: description of a new mutation and clinical and electroencephalographic analysis. ( Carrascosa-Romero, MC; de Cabo-de la Vega, C; Gil-Pons, E; Iniesta-López, I; Martínez-Gutiérrez, A; Pardal-Fernández, JM, 2009)
"Senegalese baboons (Papio papio), with a natural syndrome of photosensitive epilepsy, consistently show generalized myoclonic jerks if stimulated stroboscopically at hourly intervals, two to eight hours after the intravenous administration of allylglycine, 200 mg/kg."3.65A primate model for testing anticonvulsant drugs. ( Horton, RW; Meldrum, BS; Toseland, PA, 1975)
" The dosage of glycine was initiated at 600 mg/day and was increased gradually until a maximum dosage of 6,000 mg/day was reached."2.66Therapeutic trial with glycine in myoclonus. ( Fahn, S; Truong, DD, 1988)
"Glycine is a major inhibitory neurotransmitter in the mammalian central nervous system, and glycinergic transmission is important for the control of both motor and sensory functions in the spinal cord."2.38Disorder of the inhibitory glycine receptor: inherited myoclonus in Poll Hereford calves. ( Gundlach, AL, 1990)
" Their beneficial effects decline with chronic administration because of drug tolerance, and the theoretical basis for BDZ responses remains unclear."2.38Myoclonus: analysis of monoamine, GABA, and other systems. ( Snodgrass, SR, 1990)
"Because of clinical similarities, benign hereditary chorea and myoclonus-dystonia (DYT11) might be confused."1.34Clinical differentiation of genetically proven benign hereditary chorea and myoclonus-dystonia. ( Asmus, F; Chinnery, PF; Devlin, A; Gasser, T; Munz, M; Zimprich, A, 2007)
"Urea may produce myoclonus by blockade of glycine receptors in the medullary reticular formation."1.27Urea-induced myoclonus: medullary glycine antagonism as mechanism of action. ( Chung, E; Van Woert, MH; Yocca, F, 1985)
"In mice, the ED(50) values for seizures following intraperitoneal injection were allylglycine 1."1.25Seizures induced by allylglycine, 3-mercaptopropionic acid and 4-deoxypyridoxine in mice and photosensitive baboons, and different modes of inhibition of cerebral glutamic acid decarboxylase. ( Horton, RW; Meldrum, BS, 1973)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199017 (62.96)18.7374
1990's3 (11.11)18.2507
2000's5 (18.52)29.6817
2010's2 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Knaepper-Martin, S1
Boix, H1
Ehmsen, JT1
Liu, Y1
Wang, Y1
Paladugu, N1
Johnson, AE1
Rothstein, JD1
du Lac, S1
Mattson, MP1
Höke, A1
Pardal-Fernández, JM1
Carrascosa-Romero, MC1
de Cabo-de la Vega, C1
Iniesta-López, I1
Gil-Pons, E1
Martínez-Gutiérrez, A1
Breitinger, HG1
Lanig, H1
Vohwinkel, C1
Grewer, C1
Breitinger, U1
Clark, T1
Becker, CM2
Asmus, F1
Devlin, A1
Munz, M1
Zimprich, A1
Gasser, T1
Chinnery, PF1
Aicardi, J1
Harris, DJ1
Thompson, RM1
Wolf, B1
Yang, BI1
Becker, L1
von Wegerer, J1
Schenkel, J1
Zeilhofer, HU1
Swandulla, D1
Weiher, H1
Schofield, PR1
Meldrum, BS3
Horton, RW2
Toseland, PA1
Gundlach, AL1
Snodgrass, SR1
Van Woert, MH4
Rosenbaum, D1
Chung, EY3
Chung, E1
Yocca, F1
Truong, DD2
Fahn, S2
Chapman, AG1
Garcia De Yebenes, J1
Pezzoli, G1
Jackson-Lewis, V1
Terasaki, T1
Yamatogi, Y1
Ohtahara, S1
Miyake, S1
Iyoda, K1
Narusawa, K1
Bachmann, C1
Mihatsch, MJ1
Baumgartner, RE1
Brechbühler, T1
Bühler, UK1
Olafsson, A1
Ohnacker, H1
Wick, H1
Seppäläinen, AM1
Similä, S1
Baumgartner, R1
Ando, T1
Nyhan, WL1
Broyer, M1
Berger, R1

Reviews

8 reviews available for glycine and Myoclonic Jerk

ArticleYear
[Amplitude-integrated electroencephalography in non-ketotic hyperglycinaemia].
    Revista de neurologia, 2014, Jan-01, Volume: 58, Issue:1

    Topics: Carnitine; Consanguinity; Dextromethorphan; Drug Therapy, Combination; Early Diagnosis; Electroencep

2014
[Myoclonias as a manifestation of degenerative disorders of the central nervous system in childhood].
    Revue d'electroencephalographie et de neurophysiologie clinique, 1982, Volume: 12, Issue:1

    Topics: Adolescent; Age Factors; Brain Diseases; Cerebellar Diseases; Ceroid; Child; Child, Preschool; Diagn

1982
The role of glycine and glycine receptors in myoclonus and startle syndromes.
    Advances in neurology, 2002, Volume: 89

    Topics: Amino Acid Sequence; Animals; Glycine; Humans; Molecular Sequence Data; Mutation; Myoclonus; Nervous

2002
Disorder of the inhibitory glycine receptor: inherited myoclonus in Poll Hereford calves.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1990, Volume: 4, Issue:10

    Topics: Animals; Brain; Cattle; Cattle Diseases; Glycine; Mutation; Myoclonus; Receptors, GABA-A; Receptors,

1990
Disorders of the inhibitory glycine receptor: the spastic mouse.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1990, Volume: 4, Issue:10

    Topics: Animals; Disease Models, Animal; Glycine; Humans; Mice; Mice, Neurologic Mutants; Movement Disorders

1990
Myoclonus: analysis of monoamine, GABA, and other systems.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1990, Volume: 4, Issue:10

    Topics: Animals; Biogenic Amines; Epilepsy; gamma-Aminobutyric Acid; Glycine; Humans; Myoclonus; Neurons; Re

1990
Drugs acting on amino acid neurotransmitters.
    Advances in neurology, 1986, Volume: 43

    Topics: Acoustic Stimulation; Amino Acids; Animals; Chemical Phenomena; Chemistry; Diazepam; Electrophysiolo

1986
Valproate and myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Aspartic Acid; Clonazepam; DDT; Disease Models, Animal; F

1986

Trials

1 trial available for glycine and Myoclonic Jerk

ArticleYear
Therapeutic trial with glycine in myoclonus.
    Movement disorders : official journal of the Movement Disorder Society, 1988, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Blood-Brain Barrier; Clinical Trials as Topic; Double-Blind Method; Female; Glyci

1988

Other Studies

18 other studies available for glycine and Myoclonic Jerk

ArticleYear
The astrocytic transporter SLC7A10 (Asc-1) mediates glycinergic inhibition of spinal cord motor neurons.
    Scientific reports, 2016, 10-19, Volume: 6

    Topics: Amino Acid Transport System y+; Animals; Astrocytes; Autoantigens; Brain; Cells, Cultured; Female; G

2016
Atypical glycine encephalopathy in an extremely low birth weight infant: description of a new mutation and clinical and electroencephalographic analysis.
    Epileptic disorders : international epilepsy journal with videotape, 2009, Volume: 11, Issue:1

    Topics: Aminomethyltransferase; Apnea; Brain; Brain Diseases, Metabolic; Electroencephalography; Fatal Outco

2009
Molecular dynamics simulation links conformation of a pore-flanking region to hyperekplexia-related dysfunction of the inhibitory glycine receptor.
    Chemistry & biology, 2004, Volume: 11, Issue:10

    Topics: Cell Line; Computer Simulation; Dose-Response Relationship, Drug; Glycine; Helix-Turn-Helix Motifs;

2004
Clinical differentiation of genetically proven benign hereditary chorea and myoclonus-dystonia.
    Movement disorders : official journal of the Movement Disorder Society, 2007, Oct-31, Volume: 22, Issue:14

    Topics: Adolescent; Arginine; Child; Chorea; DNA Mutational Analysis; Dystonic Disorders; Exons; Family Heal

2007
Propionyl coenzyme A carboxylase deficiency presenting as non-ketotic hyperglycinaemia.
    Journal of medical genetics, 1981, Volume: 18, Issue:2

    Topics: Carboxy-Lyases; Female; Glycine; Humans; Infant; Ketosis; Methylmalonyl-CoA Decarboxylase; Myoclonus

1981
Disease-specific human glycine receptor alpha1 subunit causes hyperekplexia phenotype and impaired glycine- and GABA(A)-receptor transmission in transgenic mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Apr-01, Volume: 22, Issue:7

    Topics: Animals; Autoradiography; Brain; Disease Models, Animal; Female; Genes, Dominant; Glycine; Humans; I

2002
A primate model for testing anticonvulsant drugs.
    Archives of neurology, 1975, Volume: 32, Issue:5

    Topics: Allyl Compounds; Animals; Anticonvulsants; Carbamazepine; Chromatography, Gas; Diazepam; Disease Mod

1975
Biochemistry and therapeutics of posthypoxic myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Aspartic Acid; Benzodiazepines; Carbidopa; Electro

1986
Possible mechanisms of action of valproic acid in myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 4-Aminobutyrate Transaminase; 5-Hydroxytryptophan; Animals; Brain; gamma-Aminobutyric Acid; Glycine;

1986
Urea-induced myoclonus: medullary glycine antagonism as mechanism of action.
    Life sciences, 1985, Mar-18, Volume: 36, Issue:11

    Topics: Animals; Benzodiazepinones; Binding, Competitive; Drug Administration Schedule; Flumazenil; Glycine;

1985
Urea myoclonus: possible involvement of glycine.
    Advances in neurology, 1986, Volume: 43

    Topics: Animals; gamma-Aminobutyric Acid; Glycine; Male; Myoclonus; Rats; Rats, Inbred Strains; Receptors, G

1986
Glycine involvement in DDT-induced myoclonus.
    Movement disorders : official journal of the Movement Disorder Society, 1988, Volume: 3, Issue:1

    Topics: Acetamides; Animals; Anticonvulsants; Brain Chemistry; DDT; Glycine; Injections, Intraperitoneal; In

1988
[A long-term follow-up study on a case with glycine encephalopathy].
    No to hattatsu = Brain and development, 1988, Volume: 20, Issue:1

    Topics: Amino Acid Metabolism, Inborn Errors; Brain Diseases, Metabolic; Child, Preschool; Diazepam; Electro

1988
Seizures induced by allylglycine, 3-mercaptopropionic acid and 4-deoxypyridoxine in mice and photosensitive baboons, and different modes of inhibition of cerebral glutamic acid decarboxylase.
    British journal of pharmacology, 1973, Volume: 49, Issue:1

    Topics: Allyl Compounds; Animals; Brain; Carboxy-Lyases; Electroencephalography; Glutamates; Glycine; Haplor

1973
[Non-ketotic hyperglycinemia: peracute course in neonatal period].
    Helvetica paediatrica acta, 1971, Volume: 26, Issue:3

    Topics: Acute Disease; Amino Acids; Biopsy; Brain; Cerebellum; Fatty Liver; Glycine; Hiccup; Humans; Infant,

1971
Electroencephalographic findings in three patients with nonketotic hyperglycinemia.
    Epilepsia, 1971, Volume: 12, Issue:1

    Topics: Amino Acid Metabolism, Inborn Errors; Electroencephalography; Glycine; Humans; Infant; Infant, Newbo

1971
Nonketotic hyperglycinemia.
    The Journal of pediatrics, 1969, Volume: 75, Issue:6

    Topics: Agranulocytosis; Amino Acid Metabolism, Inborn Errors; Benzoates; Body Weight; Carbon Isotopes; Diet

1969
[Glycinosis (hyperglycinemia)].
    La Presse medicale, 1968, Nov-23, Volume: 76, Issue:45

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child Development; Child, Preschool; Ch

1968