glycine has been researched along with Myocardial Ischemia in 41 studies
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Excerpt | Relevance | Reference |
---|---|---|
"Leonurine has been shown to have excellent anti-myocardial ischemia effects." | 8.12 | Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver-Cardiac Crosstalk Metabolomics Study. ( Li, J; Lu, Q; Pan, D; Rong, W; Wang, A; Wang, L; Zhang, Y; Zhou, Q; Zhu, Q; Zhu, Y, 2022) |
"The role of hydrogen sulfide (H(2)S) in myocardial infarction (MI) has not been previously studied." | 7.74 | Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats. ( Ho, P; Huang, SH; Loke, YY; Lu, J; Moore, PK; Tan, CS; Wang, ZJ; Whiteman, M; Zhu, YC; Zhu, YZ, 2007) |
" The overall aim of this study was to determine if adrenomedullin (AM) protects against myocardial ischaemia (MI)-induced arrhythmias via nitric oxide (NO) and peroxynitrite." | 7.73 | Adrenomedullin acts via nitric oxide and peroxynitrite to protect against myocardial ischaemia-induced arrhythmias in anaesthetized rats. ( Kane, KA; Looi, YH; McPhaden, AR; Wainwright, CL, 2006) |
"We investigated whether (endogenous) hydrogen sulfide (H2S) protects the heart against myocardial ischemia and reperfusion injury." | 7.73 | The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat. ( McDonald, MC; Sivarajah, A; Thiemermann, C, 2006) |
"Coronary thrombosis was produced by insertion of a thrombogenic copper coil into the LAD of 40 anesthetized pigs." | 5.30 | Coronary thrombosis/thrombolysis in pigs: effects of heparin, ASA, and the thrombin inhibitor inogatran. ( Hatori, N; Mattsson, C; Nordlander, R; Rydén, L; Sjöquist, PO; Uriuda, Y; Wang, QD, 1998) |
"Leonurine has been shown to have excellent anti-myocardial ischemia effects." | 4.12 | Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver-Cardiac Crosstalk Metabolomics Study. ( Li, J; Lu, Q; Pan, D; Rong, W; Wang, A; Wang, L; Zhang, Y; Zhou, Q; Zhu, Q; Zhu, Y, 2022) |
"The role of hydrogen sulfide (H(2)S) in myocardial infarction (MI) has not been previously studied." | 3.74 | Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats. ( Ho, P; Huang, SH; Loke, YY; Lu, J; Moore, PK; Tan, CS; Wang, ZJ; Whiteman, M; Zhu, YC; Zhu, YZ, 2007) |
" The overall aim of this study was to determine if adrenomedullin (AM) protects against myocardial ischaemia (MI)-induced arrhythmias via nitric oxide (NO) and peroxynitrite." | 3.73 | Adrenomedullin acts via nitric oxide and peroxynitrite to protect against myocardial ischaemia-induced arrhythmias in anaesthetized rats. ( Kane, KA; Looi, YH; McPhaden, AR; Wainwright, CL, 2006) |
"We investigated whether (endogenous) hydrogen sulfide (H2S) protects the heart against myocardial ischemia and reperfusion injury." | 3.73 | The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat. ( McDonald, MC; Sivarajah, A; Thiemermann, C, 2006) |
" The effects of microinjection of glutamate and glycine in bilateral rostral ventrolateral medulla (rVLM) on the reaction of electroacupuncture (EA) of "Neiguan" acupoint (PC 6) after myocardial ischemia by ligature of the left ventricular branch of coronary artery were observed." | 3.69 | [Influence of neuronal excitation and inhibition of rostral ventrolateral medulla on the effect of electroacupuncture of "Neiguan" acupoint]. ( Cao, Q; Chen, S; Liu, J; Zhang, J, 1996) |
"Unstable coronary artery disease is in most cases associated with plaque rupture, activation of the coagulation system and subsequent intracoronary thrombus formation which may cause myocardial cell damage." | 2.71 | Myocardial damage, coagulation activity and the response to thrombin inhibition in unstable coronary artery disease. ( Grip, L; Linder, R; Oldgren, J; Siegbahn, A; Thygesen, K; Wallentin, L, 2004) |
"Hydrogen sulfide (H( 2)S) is a biological mediator produced by enzyme-regulated pathways from L-cysteine, which is a substrate for cystathionine-gamma-lyase (CSE)." | 1.36 | L-cysteine stimulates hydrogen sulfide synthesis in myocardium associated with attenuation of ischemia-reperfusion injury. ( Baxter, GF; Elsey, DJ; Fowkes, RC, 2010) |
"Sivelestat was infused intracoronally at concentrations of 6 and 60 mg/ml throughout the reperfusion period in groups L and H, respectively, while saline was infused in the group C." | 1.36 | Postischemic infusion of sivelestat sodium hydrate, a selective neutrophil elastase inhibitor, protects against myocardial stunning in swine. ( Akiyama, D; Cho, S; Hara, T; Maekawa, T; Sumikawa, K; Yoshitomi, O, 2010) |
"Nicorandil is a hybrid of nitrate and a K(ATP) channel opener that activates the sarcK(ATP) and mitoK(ATP) channels." | 1.31 | Infarct size limitation by nicorandil: roles of mitochondrial K(ATP) channels, sarcolemmal K(ATP) channels, and protein kinase C. ( Ichikawa, Y; Kuno, A; Matsumoto, T; Miki, T; Miura, T; Ohnuma, Y; Sakamoto, J; Shimamoto, K; Tanno, M; Tsuchida, A, 2002) |
"Coronary thrombosis was produced by insertion of a thrombogenic copper coil into the LAD of 40 anesthetized pigs." | 1.30 | Coronary thrombosis/thrombolysis in pigs: effects of heparin, ASA, and the thrombin inhibitor inogatran. ( Hatori, N; Mattsson, C; Nordlander, R; Rydén, L; Sjöquist, PO; Uriuda, Y; Wang, QD, 1998) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 12 (29.27) | 18.2507 |
2000's | 20 (48.78) | 29.6817 |
2010's | 7 (17.07) | 24.3611 |
2020's | 2 (4.88) | 2.80 |
Authors | Studies |
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Rong, W | 1 |
Li, J | 1 |
Pan, D | 1 |
Zhou, Q | 1 |
Zhang, Y | 1 |
Lu, Q | 1 |
Wang, L | 1 |
Wang, A | 1 |
Zhu, Y | 1 |
Zhu, Q | 1 |
Sánchez, G | 2 |
Chalmers, S | 1 |
Ahumada, X | 1 |
Montecinos, L | 2 |
Olmedo, I | 2 |
Eisner, V | 1 |
Riveros, A | 1 |
Kogan, MJ | 1 |
Lavandero, S | 1 |
Pedrozo, Z | 2 |
Donoso, P | 2 |
Li, G | 1 |
Lv, J | 1 |
Wang, J | 1 |
Wan, P | 1 |
Li, Y | 1 |
Jiang, H | 1 |
Jin, Q | 1 |
Berrios, D | 1 |
Pezoa, J | 1 |
Riquelme, JA | 1 |
José Alburquerque-Béjar, J | 1 |
Barba, I | 1 |
Valls-Lacalle, L | 1 |
Ruiz-Meana, M | 2 |
Pecoraro, M | 1 |
Rodríguez-Sinovas, A | 2 |
García-Dorado, D | 2 |
Kambe, M | 1 |
Bessho, R | 1 |
Fujii, M | 1 |
Ochi, M | 1 |
Shimizu, K | 1 |
Elsey, DJ | 1 |
Fowkes, RC | 1 |
Baxter, GF | 1 |
Akiyama, D | 1 |
Hara, T | 1 |
Yoshitomi, O | 1 |
Maekawa, T | 1 |
Cho, S | 1 |
Sumikawa, K | 1 |
Kang, SM | 1 |
Park, JC | 1 |
Shin, MJ | 1 |
Lee, H | 1 |
Oh, J | 1 |
Ryu, DH | 1 |
Hwang, GS | 1 |
Chung, JH | 1 |
Marina Prendes, MG | 2 |
Hermann, R | 1 |
Torresin, ME | 1 |
Souto, P | 1 |
Tallis, S | 1 |
Savino, EA | 2 |
Varela, A | 2 |
Jaitovich, MM | 1 |
Tsuchida, A | 1 |
Miura, T | 1 |
Tanno, M | 1 |
Sakamoto, J | 1 |
Miki, T | 1 |
Kuno, A | 1 |
Matsumoto, T | 1 |
Ohnuma, Y | 1 |
Ichikawa, Y | 1 |
Shimamoto, K | 1 |
Fuller, W | 1 |
Parmar, V | 1 |
Eaton, P | 2 |
Bell, JR | 1 |
Shattock, MJ | 2 |
Chandler, MP | 1 |
Chavez, PN | 1 |
McElfresh, TA | 1 |
Huang, H | 1 |
Harmon, CS | 1 |
Stanley, WC | 1 |
Canton, M | 1 |
Neverova, I | 1 |
Menabò, R | 1 |
Van Eyk, J | 1 |
Di Lisa, F | 1 |
Oldgren, J | 1 |
Siegbahn, A | 1 |
Grip, L | 1 |
Linder, R | 1 |
Thygesen, K | 1 |
Wallentin, L | 1 |
Pina, P | 1 |
Soler-Soler, J | 1 |
Lecour, S | 1 |
Rochette, L | 1 |
Opie, L | 1 |
Chu, Y | 1 |
Alwahdani, A | 1 |
Iida, S | 1 |
Lund, DD | 1 |
Faraci, FM | 1 |
Heistad, DD | 1 |
Broderick, TL | 1 |
Glick, B | 1 |
Looi, YH | 1 |
Kane, KA | 1 |
McPhaden, AR | 1 |
Wainwright, CL | 1 |
García, JV | 1 |
Testoni, G | 1 |
Fernández, MA | 1 |
Perazzo, JC | 1 |
Sivarajah, A | 1 |
McDonald, MC | 1 |
Thiemermann, C | 1 |
Zhu, YZ | 1 |
Wang, ZJ | 1 |
Ho, P | 1 |
Loke, YY | 1 |
Zhu, YC | 1 |
Huang, SH | 1 |
Tan, CS | 1 |
Whiteman, M | 1 |
Lu, J | 1 |
Moore, PK | 1 |
Liu, Y | 1 |
Yang, XM | 1 |
Iliodromitis, EK | 1 |
Kremastinos, DT | 1 |
Dost, T | 1 |
Cohen, MV | 1 |
Downey, JM | 1 |
Gandhi, M | 1 |
Finegan, BA | 1 |
Clanachan, AS | 1 |
Madden, MC | 1 |
Wołkowicz, PE | 1 |
Pohost, GM | 1 |
McMillin, JB | 1 |
Pike, MM | 1 |
Meehan, AG | 2 |
Higgins, AJ | 2 |
Bellemin-Baurreau, J | 1 |
Poizot, A | 1 |
Hicks, PE | 1 |
Armstrong, JM | 1 |
Yamada, KA | 1 |
McHowat, J | 1 |
Yan, GX | 1 |
Donahue, K | 1 |
Peirick, J | 1 |
Kléber, AG | 1 |
Corr, PB | 1 |
Hahn, RG | 1 |
Liu, J | 1 |
Chen, S | 1 |
Cao, Q | 1 |
Zhang, J | 1 |
Andersen, K | 2 |
Dellborg, M | 2 |
Uriuda, Y | 1 |
Wang, QD | 1 |
Hatori, N | 1 |
Nordlander, R | 1 |
Sjöquist, PO | 1 |
Mattsson, C | 1 |
Rydén, L | 1 |
Li, JM | 1 |
Hearse, DJ | 1 |
Holmvang, L | 1 |
Clemmensen, P | 1 |
Wagner, G | 1 |
Grande, P | 1 |
Abrahamsson, P | 1 |
Zaslavskaia, RM | 2 |
Kelimberdieva, ES | 2 |
Komissarova, IA | 2 |
Teĭblium, MM | 2 |
Goncharov, LF | 1 |
Goncharova, ZF | 1 |
Akhmetov, KZh | 1 |
Tripathi, Y | 1 |
Hegde, BM | 1 |
Rai, YS | 1 |
Raghuveer, CV | 1 |
Kalinina, EV | 1 |
Humma, LM | 1 |
Puckett, BJ | 1 |
Richardson, HE | 1 |
Terra, SG | 1 |
Andrisin, TE | 1 |
Lejeune, BL | 1 |
Wallace, MR | 1 |
Lewis, JF | 1 |
McNamara, DM | 1 |
Picoult-Newberg, L | 1 |
Pepine, CJ | 1 |
Johnson, JA | 1 |
Fan, H | 1 |
Sun, B | 1 |
Gu, Q | 1 |
Lafond-Walker, A | 1 |
Cao, S | 1 |
Becker, LC | 1 |
5 trials available for glycine and Myocardial Ischemia
Article | Year |
---|---|
Myocardial damage, coagulation activity and the response to thrombin inhibition in unstable coronary artery disease.
Topics: Adult; Aged; Biomarkers; Blood Coagulation; Coronary Artery Disease; Glycine; Heparin; Humans; Middl | 2004 |
Heparin is more effective than inogatran, a low-molecular weight thrombin inhibitor in suppressing ischemia and recurrent angina in unstable coronary disease. Thrombin Inhibition in Myocardial Ischemia (TRIM) Study Group.
Topics: Adult; Aged; Aged, 80 and over; Angina, Unstable; Anticoagulants; Antithrombins; Double-Blind Method | 1998 |
Relative contributions of a single-admission 12-lead electrocardiogram and early 24-hour continuous electrocardiographic monitoring for early risk stratification in patients with unstable coronary artery disease.
Topics: Aged; Angina Pectoris; Angina, Unstable; Anticoagulants; Antithrombins; Coronary Disease; Electrocar | 1999 |
[Comparative efficacy of combined therapy with preductal and amino acid composition in elderly patients with coronary heart disease and class II-III angina].
Topics: Aged; Aged, 80 and over; Angina Pectoris; Cysteine; Drug Therapy, Combination; Echocardiography; Ele | 1999 |
[Parameters of hemodynamics and red cell redox-status in old patients with ischemic heart disease].
Topics: Aged; Antioxidants; Biomarkers; Cysteine; Electrocardiography, Ambulatory; Erythrocytes; Female; Glu | 2000 |
36 other studies available for glycine and Myocardial Ischemia
Article | Year |
---|---|
Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver-Cardiac Crosstalk Metabolomics Study.
Topics: Amino Acids; Animals; Coronary Artery Disease; Fatty Acids; Glycine; Liver; Metabolomics; Myocardial | 2022 |
Inhibition of chymotrypsin-like activity of the proteasome by ixazomib prevents mitochondrial dysfunction during myocardial ischemia.
Topics: Animals; Boron Compounds; Chymotrypsin; Disease Models, Animal; Glutathione; Glycine; Heart; Humans; | 2020 |
GABAB receptors in the hippocampal dentate gyrus are involved in spatial learning and memory impairment in a rat model of vascular dementia.
Topics: Animals; Baclofen; Dementia, Vascular; Dentate Gyrus; Disease Models, Animal; GABA Antagonists; GABA | 2016 |
Activation of Chymotrypsin-Like Activity of the Proteasome during Ischemia Induces Myocardial Dysfunction and Death.
Topics: Adenosine Triphosphate; Animals; Boron Compounds; Caspase 3; Cell Death; Chymotrypsin; Dose-Response | 2016 |
Remote ischemic conditioning provides humoural cross-species cardioprotection through glycine receptor activation.
Topics: Animals; Biomarkers; Discriminant Analysis; Disease Models, Animal; Excitatory Amino Acid Antagonist | 2017 |
Sivelestat reduces myocardial ischemia and reperfusion injury in rat hearts even when administered after onset of myocardial ischemia.
Topics: Acetylcholine; Animals; Cardiotonic Agents; Coronary Circulation; Dose-Response Relationship, Drug; | 2009 |
L-cysteine stimulates hydrogen sulfide synthesis in myocardium associated with attenuation of ischemia-reperfusion injury.
Topics: Alkynes; Analysis of Variance; Animals; Cysteine; Disease Models, Animal; Drug Therapy, Combination; | 2010 |
Postischemic infusion of sivelestat sodium hydrate, a selective neutrophil elastase inhibitor, protects against myocardial stunning in swine.
Topics: Animals; Coronary Circulation; Female; Glycine; Interleukin-6; Male; Myocardial Ischemia; Myocardial | 2010 |
¹H nuclear magnetic resonance based metabolic urinary profiling of patients with ischemic heart failure.
Topics: Acetic Acid; Acetone; Aged; Case-Control Studies; Cytosine; Energy Metabolism; Female; Glycine; Hear | 2011 |
Involvement of energetic metabolism in the effects of ischemic postconditioning on the ischemic-reperfused heart of fed and fasted rats.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cell Survival; Energy Metabolism; Fasting; Female; | 2011 |
Infarct size limitation by nicorandil: roles of mitochondrial K(ATP) channels, sarcolemmal K(ATP) channels, and protein kinase C.
Topics: Animals; Benzamides; Decanoic Acids; Enzyme Inhibitors; Glycine; Hemodynamics; Hydroxy Acids; In Vit | 2002 |
Cardiac ischemia causes inhibition of the Na/K ATPase by a labile cytosolic compound whose production is linked to oxidant stress.
Topics: Animals; Antioxidants; Biological Assay; Biological Factors; Cytosol; Enzyme Inhibitors; Glycine; Ma | 2003 |
Partial inhibition of fatty acid oxidation increases regional contractile power and efficiency during demand-induced ischemia.
Topics: Animals; Blood Glucose; Carnitine O-Palmitoyltransferase; Fatty Acids; Fatty Acids, Nonesterified; G | 2003 |
Evidence of myofibrillar protein oxidation induced by postischemic reperfusion in isolated rat hearts.
Topics: Actins; Animals; Carbon; Glycine; Hydrogen Peroxide; In Vitro Techniques; Male; Myocardial Ischemia; | 2004 |
Effect of sarcolemmal rupture on myocardial electrical impedance during oxygen deprivation.
Topics: Acids; Animals; Cell Death; Cells, Cultured; Detergents; Electric Impedance; Energy Metabolism; Glyc | 2005 |
Free radicals trigger TNF alpha-induced cardioprotection.
Topics: Animals; Antioxidants; Electron Spin Resonance Spectroscopy; Free Radicals; Glycine; Ischemic Precon | 2005 |
Vascular effects of the human extracellular superoxide dismutase R213G variant.
Topics: Amino Acid Substitution; Animals; Arginine; Diabetic Nephropathies; Disease Models, Animal; Gene Tra | 2005 |
Effect of gender and fatty acids on ischemic recovery of contractile and pump function in the rat heart.
Topics: Analysis of Variance; Animals; Fatty Acids; Female; Glycine; Male; Myocardial Contraction; Myocardia | 2004 |
Adrenomedullin acts via nitric oxide and peroxynitrite to protect against myocardial ischaemia-induced arrhythmias in anaesthetized rats.
Topics: Adrenomedullin; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; | 2006 |
Influence of fasting on the effects of dimethylamiloride and oxfenicine on ischaemic-reperfused rat hearts.
Topics: Amiloride; Animals; Carnitine O-Palmitoyltransferase; Cell Survival; Enzyme Inhibitors; Fasting; Fat | 2006 |
The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat.
Topics: Alkynes; Animals; Cardiotonic Agents; Cystathionine gamma-Lyase; Decanoic Acids; Endotoxins; Enzyme | 2006 |
Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats.
Topics: Alkynes; Animals; Cell Death; Cells, Cultured; Culture Media; Cystathionine gamma-Lyase; Disease Mod | 2007 |
Redox signaling at reperfusion is required for protection from ischemic preconditioning but not from a direct PKC activator.
Topics: Analysis of Variance; Animals; Free Radical Scavengers; Glycine; Heart; Hemodynamics; Ischemic Preco | 2008 |
Role of glucose metabolism in the recovery of postischemic LV mechanical function: effects of insulin and other metabolic modulators.
Topics: Adenosine; Animals; Dichloroacetic Acid; Energy Metabolism; Enzyme Inhibitors; Glucose; Glycine; Gly | 2008 |
Acylcarnitine accumulation does not correlate with reperfusion recovery in palmitate-perfused rat hearts.
Topics: Acylation; Adenosine Triphosphate; Animals; Blood Pressure; Caproates; Carnitine; Carnitine O-Palmit | 1995 |
Exacerbation of both ischemic and reperfusion damage by fatty acid in working rat hearts.
Topics: Animals; Fatty Acids; Glycine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Oleic Acid; | 1994 |
Oleate plus oxfenicine improves functional recovery, assessed via an intraventricular balloon, in ischemic-reperfused rat hearts.
Topics: Animals; Glycine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Oleic Acid; Oleic Acids; | 1994 |
An in vitro method for the evaluation of antiarrhythmic and antiischemic agents by using programmed electrical stimulation of rabbit heart.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Electric Stimulation; Glycine; Heart; | 1994 |
Cellular uncoupling induced by accumulation of long-chain acylcarnitine during ischemia.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Electrophysiology; Epoxy Compounds; Glycine; H | 1994 |
Silent myocardial ischaemia and fluid absorption.
Topics: Glycine; Humans; Male; Myocardial Ischemia; Prostatectomy; Therapeutic Irrigation | 1997 |
[Influence of neuronal excitation and inhibition of rostral ventrolateral medulla on the effect of electroacupuncture of "Neiguan" acupoint].
Topics: Acupuncture Points; Animals; Blood Pressure; Electroacupuncture; Female; Glutamates; Glycine; Male; | 1996 |
Coronary thrombosis/thrombolysis in pigs: effects of heparin, ASA, and the thrombin inhibitor inogatran.
Topics: Animals; Antithrombins; Aspirin; Blood Flow Velocity; Coronary Thrombosis; Glycine; Hemodynamics; He | 1998 |
Formation of 4-hydroxy-2-nonenal-modified proteins in ischemic rat heart.
Topics: Aldehydes; Animals; Antioxidants; Fluorescent Antibody Technique; Glycine; In Vitro Techniques; Male | 1999 |
Effect of N-2-mercaptopropionylglycine in limiting myocardial reperfusion injury following 90 minutes of ischemia in dogs.
Topics: Animals; Antioxidants; Dogs; Glutathione; Glycine; Lipid Peroxidation; Male; Myocardial Ischemia; My | 2000 |
Effects of beta1-adrenoceptor genetic polymorphisms on resting hemodynamics in patients undergoing diagnostic testing for ischemia.
Topics: Adult; Aged; Arginine; Codon; Echocardiography, Stress; Female; Genotype; Glycine; Humans; Male; Mid | 2001 |
Oxygen radicals trigger activation of NF-kappaB and AP-1 and upregulation of ICAM-1 in reperfused canine heart.
Topics: Animals; Blood Flow Velocity; Blotting, Northern; Constriction; Coronary Vessels; DNA; Dogs; Free Ra | 2002 |