Page last updated: 2024-10-18

glycine and Muscular Dystrophy, Duchenne

glycine has been researched along with Muscular Dystrophy, Duchenne in 5 studies

Muscular Dystrophy, Duchenne: An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)

Research Excerpts

ExcerptRelevanceReference
"The L-arginine/nitric oxide synthase (NOS) pathway is considered to be altered in muscular dystrophy such as Becker muscular dystrophy (BMD)."9.27Effects of single and combined metformin and L-citrulline supplementation on L-arginine-related pathways in Becker muscular dystrophy patients: possible biochemical and clinical implications. ( Bollenbach, A; Bonati, U; Fischer, D; Hafner, P; Hanff, E; Kayacelebi, AA; Tsikas, D, 2018)
"The L-arginine/nitric oxide synthase (NOS) pathway is considered to be altered in muscular dystrophy such as Becker muscular dystrophy (BMD)."5.27Effects of single and combined metformin and L-citrulline supplementation on L-arginine-related pathways in Becker muscular dystrophy patients: possible biochemical and clinical implications. ( Bollenbach, A; Bonati, U; Fischer, D; Hafner, P; Hanff, E; Kayacelebi, AA; Tsikas, D, 2018)
"Treatment with ixazomib had no toxic effect on the mdx mouse."1.62Ixazomib, an oral proteasome inhibitor, exhibits potential effect in dystrophin-deficient mdx mice. ( Bertassoli, BM; Carvalho, AAS; Feder, D; Fonseca, FLA; Hermes, TA; Micheletto, MLJ; Perez, MM; Petri, G, 2021)
"Glycine treatment attenuated fibrotic deposition in the diaphragm by 28% (Pā€‰<ā€‰0."1.51Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice. ( Alves, FM; Caldow, MK; Chee, A; Gardner, A; Ham, DJ; Kennedy, TL; Koopman, R; Lynch, GS; Naim, T; Trieu, J, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Han, G4
Lin, C4
Yin, H4
Ham, DJ1
Gardner, A1
Kennedy, TL1
Trieu, J1
Naim, T1
Chee, A1
Alves, FM1
Caldow, MK1
Lynch, GS1
Koopman, R1
Ning, H1
Song, J1
Ran, N1
Yi, X1
Seow, Y1
Micheletto, MLJ1
Hermes, TA1
Bertassoli, BM1
Petri, G1
Perez, MM1
Fonseca, FLA1
Carvalho, AAS1
Feder, D1
Hanff, E1
Hafner, P1
Bollenbach, A1
Bonati, U1
Kayacelebi, AA1
Fischer, D1
Tsikas, D1

Trials

1 trial available for glycine and Muscular Dystrophy, Duchenne

ArticleYear
Effects of single and combined metformin and L-citrulline supplementation on L-arginine-related pathways in Becker muscular dystrophy patients: possible biochemical and clinical implications.
    Amino acids, 2018, Volume: 50, Issue:10

    Topics: Adult; Amidinotransferases; Arginine; Citrulline; Creatinine; Dietary Supplements; Female; Glycine;

2018

Other Studies

4 other studies available for glycine and Muscular Dystrophy, Duchenne

ArticleYear
Use of Glycine to Augment Exon Skipping and Cell Therapies for Duchenne Muscular Dystrophy.
    Methods in molecular biology (Clifton, N.J.), 2023, Volume: 2587

    Topics: Animals; Dystrophin; Exons; Fabaceae; Glycine; Mice; Muscular Dystrophy, Duchenne; Oligonucleotides,

2023
Use of Glycine to Augment Exon Skipping and Cell Therapies for Duchenne Muscular Dystrophy.
    Methods in molecular biology (Clifton, N.J.), 2023, Volume: 2587

    Topics: Animals; Dystrophin; Exons; Fabaceae; Glycine; Mice; Muscular Dystrophy, Duchenne; Oligonucleotides,

2023
Use of Glycine to Augment Exon Skipping and Cell Therapies for Duchenne Muscular Dystrophy.
    Methods in molecular biology (Clifton, N.J.), 2023, Volume: 2587

    Topics: Animals; Dystrophin; Exons; Fabaceae; Glycine; Mice; Muscular Dystrophy, Duchenne; Oligonucleotides,

2023
Use of Glycine to Augment Exon Skipping and Cell Therapies for Duchenne Muscular Dystrophy.
    Methods in molecular biology (Clifton, N.J.), 2023, Volume: 2587

    Topics: Animals; Dystrophin; Exons; Fabaceae; Glycine; Mice; Muscular Dystrophy, Duchenne; Oligonucleotides,

2023
Use of Glycine to Augment Exon Skipping and Cell Therapies for Duchenne Muscular Dystrophy.
    Methods in molecular biology (Clifton, N.J.), 2023, Volume: 2587

    Topics: Animals; Dystrophin; Exons; Fabaceae; Glycine; Mice; Muscular Dystrophy, Duchenne; Oligonucleotides,

2023
Use of Glycine to Augment Exon Skipping and Cell Therapies for Duchenne Muscular Dystrophy.
    Methods in molecular biology (Clifton, N.J.), 2023, Volume: 2587

    Topics: Animals; Dystrophin; Exons; Fabaceae; Glycine; Mice; Muscular Dystrophy, Duchenne; Oligonucleotides,

2023
Use of Glycine to Augment Exon Skipping and Cell Therapies for Duchenne Muscular Dystrophy.
    Methods in molecular biology (Clifton, N.J.), 2023, Volume: 2587

    Topics: Animals; Dystrophin; Exons; Fabaceae; Glycine; Mice; Muscular Dystrophy, Duchenne; Oligonucleotides,

2023
Use of Glycine to Augment Exon Skipping and Cell Therapies for Duchenne Muscular Dystrophy.
    Methods in molecular biology (Clifton, N.J.), 2023, Volume: 2587

    Topics: Animals; Dystrophin; Exons; Fabaceae; Glycine; Mice; Muscular Dystrophy, Duchenne; Oligonucleotides,

2023
Use of Glycine to Augment Exon Skipping and Cell Therapies for Duchenne Muscular Dystrophy.
    Methods in molecular biology (Clifton, N.J.), 2023, Volume: 2587

    Topics: Animals; Dystrophin; Exons; Fabaceae; Glycine; Mice; Muscular Dystrophy, Duchenne; Oligonucleotides,

2023
Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice.
    Scientific reports, 2019, 09-10, Volume: 9, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Glycine; Glycine Agents; Male; Mice; Mice

2019
Glycine Enhances Satellite Cell Proliferation, Cell Transplantation, and Oligonucleotide Efficacy in Dystrophic Muscle.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2020, 05-06, Volume: 28, Issue:5

    Topics: Animals; Cell Proliferation; Cell Transplantation; Disease Models, Animal; Drug Synergism; Glycine;

2020
Ixazomib, an oral proteasome inhibitor, exhibits potential effect in dystrophin-deficient mdx mice.
    International journal of experimental pathology, 2021, Volume: 102, Issue:1

    Topics: Animals; Boron Compounds; Dystrophin; Glycine; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystroph

2021