Page last updated: 2024-10-18

glycine and Muscle Contraction

glycine has been researched along with Muscle Contraction in 82 studies

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"The aim of the present study was to investigate whether the synthesis of endogenous hydrogen sulfide (H2 S) was altered in achalasia patients and to determine the effects of H2 S on esophageal motility."7.81Reduction of hydrogen sulfide synthesis enzymes in the esophagus of patients with achalasia: effect of hydrogen sulfide in achalasia. ( Jin, H; Wang, B; Wang, T; Zhang, L; Zhao, C; Zhao, W; Zheng, Z; Zhou, G, 2015)
"Hydrogen sulfide (H₂S), recently considered the third endogenous gaseous transmitter, may have an important role in systemic inflammation."7.77Involvement of endogenous hydrogen sulfide in cigarette smoke-induced changes in airway responsiveness and inflammation of rat lung. ( Chen, YH; He, YJ; Qi, YF; Tang, CS; Wang, PP; Wang, XM; Yao, WZ, 2011)
"To investigate the effects of glycine on the recovery of bladder smooth muscle contractility after acute urinary retention."7.73Effect of glycine on recovery of bladder smooth muscle contractility after acute urinary retention in rats. ( Choi, H; Hong, SK; Kim, SW; Oh, SJ; Son, H, 2005)
"Glycine (GLY) is a neutral amino acid that has been shown to be cytoprotective in the kidneys of dogs and rabbits undergoing ischemia-reperfusion injury."7.71Glycine preserves function and decreases necrosis in skeletal muscle undergoing ischemia and reperfusion injury. ( Ascher, E; Cheng, W; Hanson, JN; Hingorani, A; Scheinman, M, 2001)
"Modulation of muscle contraction is a new function for glycine."5.26Modulation of arterial muscle contraction in Aplysia by glycine and neuron R14. ( Blankenship, JE; McAdoo, DJ; Price, CH; Sawada, M, 1981)
"The aim of the present study was to investigate whether the synthesis of endogenous hydrogen sulfide (H2 S) was altered in achalasia patients and to determine the effects of H2 S on esophageal motility."3.81Reduction of hydrogen sulfide synthesis enzymes in the esophagus of patients with achalasia: effect of hydrogen sulfide in achalasia. ( Jin, H; Wang, B; Wang, T; Zhang, L; Zhao, C; Zhao, W; Zheng, Z; Zhou, G, 2015)
"Hydrogen sulfide (H₂S), recently considered the third endogenous gaseous transmitter, may have an important role in systemic inflammation."3.77Involvement of endogenous hydrogen sulfide in cigarette smoke-induced changes in airway responsiveness and inflammation of rat lung. ( Chen, YH; He, YJ; Qi, YF; Tang, CS; Wang, PP; Wang, XM; Yao, WZ, 2011)
"To investigate the effects of glycine on the recovery of bladder smooth muscle contractility after acute urinary retention."3.73Effect of glycine on recovery of bladder smooth muscle contractility after acute urinary retention in rats. ( Choi, H; Hong, SK; Kim, SW; Oh, SJ; Son, H, 2005)
"Glycine (GLY) is a neutral amino acid that has been shown to be cytoprotective in the kidneys of dogs and rabbits undergoing ischemia-reperfusion injury."3.71Glycine preserves function and decreases necrosis in skeletal muscle undergoing ischemia and reperfusion injury. ( Ascher, E; Cheng, W; Hanson, JN; Hingorani, A; Scheinman, M, 2001)
" The receptors for glutamic acid (L-Glu) present in the guinea-pig myenteric plexus-ileal longitudinal muscle preparation have been studied by measuring the muscle contraction induced by numerous putative endogenous agonists acting at these receptors."3.67Agonists, antagonists and modulators of excitatory amino acid receptors in the guinea-pig myenteric plexus. ( Franchi-Micheli, S; Gori, AM; Luzzi, S; Moroni, F; Zilletti, L, 1988)
"There was a greater numerical difference in geometric mean PD20 values between low- and high-dose albuterol after placebo dosing (671 micrograms vs 1080 micrograms, a 1."2.69In vivo effect of albuterol on methacholine-contracted bronchi in conjunction with salmeterol and formoterol. ( Aziz, I; Lipworth, BJ, 1999)
"Glycine also has a minor role in PNS inhibition of the nociceptive bladder reflex."1.43Role of glycine in nociceptive and non-nociceptive bladder reflexes and pudendal afferent inhibition of these reflexes in cats. ( de Groat, WC; Lee, A; Reese, JN; Rogers, MJ; Roppolo, JR; Shen, B; Tai, C; Wang, J; Xiao, Z, 2016)
"Glycine treatment during tachykinin- and acetylcholine-induced contractions significantly decreased the maintenance of muscle force compared to control."1.37Novel expression of a functional glycine receptor chloride channel that attenuates contraction in airway smooth muscle. ( Emala, CW; Gallos, G; Xu, D; Yim, PD; Zhang, Y, 2011)
" This observation can be interpreted as indication that within this dosage range there is an absence of morphine-like subjective effects."1.28Analogs of the delta opioid receptor selective cyclic peptide [2-D-penicillamine,5-D-penicillamine]-enkephalin: 2',6'-dimethyltyrosine and Gly3-Phe4 amide bond isostere substitutions. ( Anthony, E; Beardsley, PM; Chandrakumar, NS; Drury, B; Lopez, OT; Reichman, M; Savage, MA; Stapelfeld, A; Williamson, LN, 1992)
" Both the glycine-extended VIP and VIP having a carboxyl group at the C-terminus caused a significant and dose-dependent inhibition of smooth muscle activity and displayed dose-response curves similar to VIP."1.28Non-amidated forms of VIP (glycine-extended VIP and VIP-free acid) have full bioactivity on smooth muscle. ( Fahrenkrug, J; Ottesen, B; Palle, C, 1989)
" 7 These data show that five of the most commonly used artificial buffers, to study muscles in vitro, exert adverse effects on contractility of arterial and venous smooth muscle."1.26Adverse effects of artificial buffers on contractile responses of arterial and venous smooth muscle. ( Altura, BM; Altura, BT; Carella, A; Turlapaty, PD, 1980)
"Glycine, which plays an inhibitory role, especially in the spinal cord, reacted with 6 per cent decrease, whereas GABA which is also considered as an inhibitory neurotransmitter showed a change of + 11 per cent on the potentiated side as compared to the unpotentiated side."1.25Neurochemical aspects of post-tetanic potentiation of monosynaptic reflexes in the cat spinal cord. I. Analysis of amino acids at maximum of potentiation. ( Behbehani, AW; Neuhoff, V; Quentin, CD, 1975)

Research

Studies (82)

TimeframeStudies, this research(%)All Research%
pre-199030 (36.59)18.7374
1990's18 (21.95)18.2507
2000's17 (20.73)29.6817
2010's15 (18.29)24.3611
2020's2 (2.44)2.80

Authors

AuthorsStudies
Heras, AF1
Veerappan, A1
Silver, RB1
Emala, CW2
Worgall, TS1
Perez-Zoghbi, J1
Worgall, S1
Nakamura, N1
Honjo, M1
Yamagishi, R1
Igarashi, N1
Sakata, R1
Aihara, M1
Wrobel, MH1
Billin, AN1
Honeycutt, SE1
McDougal, AV1
Kerr, JP1
Chen, Z1
Freudenberg, JM1
Rajpal, DK1
Luo, G1
Kramer, HF1
Geske, RS1
Fang, F1
Yao, B1
Clark, RV1
Lepore, J1
Cobitz, A1
Miller, R1
Nosaka, K1
Hinken, AC1
Russell, AJ1
Huang, X1
Meng, XM1
Liu, DH1
Wu, YS1
Guo, X1
Lu, HL1
Zhuang, XY1
Kim, YC1
Xu, WX1
Sugaya, K2
Nishijima, S2
Kadekawa, K1
Ashitomi, K1
Ueda, T1
Yamamoto, H1
Martinez-Cutillas, M1
Gil, V1
Mañé, N1
Clavé, P1
Gallego, D1
Martin, MT1
Jimenez, M1
Mei, Y1
Xu, L1
Mowrey, DD1
Mendez Giraldez, R1
Wang, Y1
Pasek, DA1
Dokholyan, NV1
Meissner, G1
Zhang, L1
Zhao, W1
Zheng, Z1
Wang, T1
Zhao, C1
Zhou, G1
Jin, H1
Wang, B1
Rogers, MJ1
Shen, B1
Reese, JN1
Xiao, Z1
Wang, J1
Lee, A1
Roppolo, JR1
de Groat, WC2
Tai, C1
Lucetti, LT1
Silva, RO1
Santana, AP1
de Melo Tavares, B1
Vale, ML1
Soares, PM1
de Lima Júnior, FJ1
Magalhães, PJ1
de Queiroz Cunha, F1
de Albuquerque Ribeiro, R1
Medeiros, JR1
Souza, MH1
Argirova, MD1
Stefanova, ID1
Krustev, AD1
Turiiski, VI1
Chen, YH1
Wang, PP1
Wang, XM1
He, YJ1
Yao, WZ1
Qi, YF1
Tang, CS1
Yim, PD1
Gallos, G1
Xu, D1
Zhang, Y1
Amemori, H1
Maeda, Y1
Torikai, A1
Nakashima, M1
Talpalar, AE1
Endo, T1
Löw, P1
Borgius, L1
Hägglund, M1
Dougherty, KJ1
Ryge, J1
Hnasko, TS1
Kiehn, O1
Rysev, NA1
Karpicheva, OE1
Redwood, CS2
Borovikov, YS1
Teague, B1
Asiedu, S1
Moore, PK1
Furukawa, Y1
Nakamaru, K1
Sasaki, K1
Fujisawa, Y1
Minakata, H1
Ohta, S1
Morishita, F1
Matsushima, O1
Li, L1
Alexeeva, V1
Ellis, TA1
Dembrow, NC1
Jing, J1
Sweedler, JV1
Weiss, KR1
Vilim, FS1
DIABLOVA, PE1
Breitenlechner, C1
Gassel, M1
Hidaka, H1
Kinzel, V1
Huber, R1
Engh, RA1
Bossemeyer, D1
Powney, EL1
West, JM1
Stephenson, DG1
Dooley, PC1
Ruggieri, RD1
Pierobon, P1
Kass-Simon, G1
La Rosée, K1
Huntgeburth, M1
Rosenkranz, S1
Böhm, M1
Schnabel, P1
Kruger, M1
Zittrich, S1
Redwood, C1
Blaudeck, N1
James, J1
Robbins, J1
Pfitzer, G1
Stehle, R1
Miyazato, M1
Shimabukuro, S1
Morozumi, M1
Ogawa, Y1
Hong, SK1
Son, H1
Kim, SW1
Oh, SJ1
Choi, H1
Takayama, N1
Uchida, K1
Shigeri, Y1
Shimamoto, K1
Ballet, S1
Salvadori, S1
Trapella, C1
Bryant, SD1
Jinsmaa, Y1
Lazarus, LH1
Negri, L1
Giannini, E1
Lattanzi, R1
Tourwé, D1
Balboni, G1
Kad, NM1
Patlak, JB1
Fagnant, PM1
Trybus, KM1
Warshaw, DM1
Robinson, P1
Lipscomb, S1
Preston, LC1
Altin, E1
Watkins, H1
Ashley, CC1
Yoshiyama, M1
Porcelloni, M1
D'Andrea, P1
Rossi, C1
Sisto, A1
Ettorre, A1
Madami, A1
Altamura, M1
Giuliani, S1
Meini, S1
Fattori, D1
Altura, BM1
Altura, BT1
Carella, A1
Turlapaty, PD1
Sillén, U1
Persson, B1
Rubenson, A1
Sawada, M2
McAdoo, DJ2
Blankenship, JE1
Price, CH2
Currie, MG1
Geller, DM1
Cole, BR1
Siegel, NR1
Fok, KF1
Adams, SP1
Eubanks, SR1
Galluppi, GR1
Needleman, P1
Ichinose, M1
Meyer, RA1
Terjung, RL1
Kadlec, O1
Schuurkes, J1
Seferna, I1
Ding, XL1
Akella, AB1
Su, H1
Gulati, J1
Jancso, A1
Szent-Györgyi, AG1
Lerche, H1
Heine, R1
Pika, U1
George, AL1
Mitrovic, N1
Browatzki, M1
Weiss, T1
Rivet-Bastide, M1
Franke, C1
Lomonaco, M1
Currie, SN1
Lee, S1
Kinouchi, Y1
Yata, N1
Savino, EA1
Varela, A1
Carregal, M1
Nozawa, Y1
Haruno, A1
Oda, N1
Yamasaki, Y1
Matsuura, N1
Miyake, H1
Yamada, S1
Kimura, R1
Monsieurs, KG1
Van Broeckhoven, C1
Martin, JJ1
Van Hoof, VO1
Heytens, L1
Wilsch, VW1
Behnisch, T1
Jäger, T1
Reymann, KG1
Balschun, D1
Sipahi, E1
Ercan, ZS1
Türker, RK1
Aziz, I1
Lipworth, BJ1
Ascher, E1
Hanson, JN1
Cheng, W1
Hingorani, A1
Scheinman, M1
Schulz, E2
Sprung, WD2
Kröning, G2
Vietinghoff, G1
Ishizawa, M1
Miyazaki, E1
Behbehani, AW1
Quentin, CD1
Neuhoff, V1
Kowalewski, K1
Zajac, S1
Kolodej, A1
Eastwood, AB1
Grundfest, H1
Brandt, PW1
Reuben, JP1
Kryzhanovskiĭ, GN1
Lutsenko, VK1
Jankowska, E1
Sorrels, TL1
Bostock, E1
Chandrakumar, NS1
Stapelfeld, A1
Beardsley, PM1
Lopez, OT1
Drury, B1
Anthony, E1
Savage, MA1
Williamson, LN1
Reichman, M1
Kim, KS1
Shin, HK1
Kim, JH1
Kang, SH1
Campbell, BG1
Couceyro, P1
Keana, JF1
Weber, E1
Moroni, F2
Alesiani, M1
Galli, A1
Mori, F1
Pecorari, R1
Carlà, V1
Cherici, G1
Pellicciari, R1
Fahrenkrug, J1
Ottesen, B1
Palle, C1
Maggi, CA1
Furio, M1
Santicioli, P1
Meli, A1
Luzzi, S1
Zilletti, L1
Franchi-Micheli, S1
Gori, AM1
Lovell, S1
Karr, T1
Harrington, WF1
Cutler, MG1
Arrol, S1
Eyre, P1
Bamgbose, SO1
Regoli, D3
Park, WK3
Rioux, F3
Choi, C1
Grzonka, Z1
Glass, JD1
Schwartz, IL1
Walter, R1
Jones, WC1
Nestor, JJ1
Du Vigneaud, V1
Wermers, GW1
Rusin, L1
Kolbeck, RC1
Cavert, HM1
Quello, CF1
Visscher, MB1
Balci, S1
Say, B1
Firat, T1
DeGroat, WC1
Budzko, DB1
Bokisch, VA1
Müller-Eberhard, HJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Administration of Saline Enema Versus Glycerin Suppository as a Treatment Intervention for Meconium Obstruction of Prematurity (MOP) and to Study the Impact on the Resolution of MOP, Time to Reach Full Enteral Feeds, Gut Microbiome, and Gut-brain Axis[NCT06048614]95 participants (Anticipated)Interventional2023-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for glycine and Muscle Contraction

ArticleYear
[Pharmacology of inhibitory amino acid transporters (GABA transporters and glycine transporters)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2006, Volume: 127, Issue:4

    Topics: Animals; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; G

2006
Interneuronal relay in spinal pathways from proprioceptors.
    Progress in neurobiology, 1992, Volume: 38, Issue:4

    Topics: Afferent Pathways; Animals; Glycine; Humans; Interneurons; Mechanoreceptors; Muscle Contraction; Neu

1992

Trials

2 trials available for glycine and Muscle Contraction

ArticleYear
HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury.
    Skeletal muscle, 2018, 11-13, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Animals; Cells, Cultured; Enzyme Inhibitors; Glycine; Humans; Hypoxia-Inducible F

2018
In vivo effect of albuterol on methacholine-contracted bronchi in conjunction with salmeterol and formoterol.
    The Journal of allergy and clinical immunology, 1999, Volume: 103, Issue:5 Pt 1

    Topics: Adrenergic beta-Agonists; Adult; Albuterol; Arginine; Bronchi; Bronchial Provocation Tests; Bronchod

1999

Other Studies

78 other studies available for glycine and Muscle Contraction

ArticleYear
Increasing Sphingolipid Synthesis Alleviates Airway Hyperreactivity.
    American journal of respiratory cell and molecular biology, 2020, Volume: 63, Issue:5

    Topics: Alveolar Epithelial Cells; Bradykinin; Bronchial Hyperreactivity; Calcium; Calcium Signaling; Fenret

2020
Effects of selective EP2 receptor agonist, omidenepag, on trabecular meshwork cells, Schlemm's canal endothelial cells and ciliary muscle contraction.
    Scientific reports, 2021, 08-10, Volume: 11, Issue:1

    Topics: Animals; Ciliary Body; Endothelial Cells; Glycine; Humans; Macaca fascicularis; Muscle Contraction;

2021
Glyphosate affects the secretion of regulators of uterine contractions in cows while it does not directly impair the motoric function of myometrium in vitro.
    Toxicology and applied pharmacology, 2018, 06-15, Volume: 349

    Topics: Animals; Cattle; Cell Survival; Cells, Cultured; Female; Glycine; Glyphosate; Herbicides; Luteal Cel

2018
Different regulatory effects of hydrogen sulfide and nitric oxide on gastric motility in mice.
    European journal of pharmacology, 2013, Nov-15, Volume: 720, Issue:1-3

    Topics: Alkynes; Aminooxyacetic Acid; Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Gastr

2013
Spinal mechanism of micturition reflex inhibition by naftopidil in rats.
    Life sciences, 2014, Oct-29, Volume: 116, Issue:2

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Amino Acids; Animals; Bicuculline; Dose-Response

2014
Potential role of the gaseous mediator hydrogen sulphide (H2S) in inhibition of human colonic contractility.
    Pharmacological research, 2015, Volume: 93

    Topics: Alkynes; Aminooxyacetic Acid; Colon; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Electri

2015
Channel Gating Dependence on Pore Lining Helix Glycine Residues in Skeletal Muscle Ryanodine Receptor.
    The Journal of biological chemistry, 2015, Jul-10, Volume: 290, Issue:28

    Topics: Amino Acid Substitution; Animals; Caffeine; Calcium Signaling; Glycine; HEK293 Cells; Humans; Ion Ch

2015
Reduction of hydrogen sulfide synthesis enzymes in the esophagus of patients with achalasia: effect of hydrogen sulfide in achalasia.
    Neurogastroenterology and motility, 2015, Volume: 27, Issue:9

    Topics: Adult; Alkynes; Aminooxyacetic Acid; Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase

2015
Role of glycine in nociceptive and non-nociceptive bladder reflexes and pudendal afferent inhibition of these reflexes in cats.
    Neurourology and urodynamics, 2016, Volume: 35, Issue:7

    Topics: Animals; Cats; Electric Stimulation; Female; Glycine; Glycine Agents; Male; Muscle Contraction; Noci

2016
Nitric Oxide and Hydrogen Sulfide Interact When Modulating Gastric Physiological Functions in Rodents.
    Digestive diseases and sciences, 2017, Volume: 62, Issue:1

    Topics: Alkynes; Animals; Central Nervous System Depressants; Cystathionine gamma-Lyase; Drug Interactions;

2017
Testing biological activity of model Maillard reaction products: studies on gastric smooth muscle tissues.
    Amino acids, 2010, Volume: 38, Issue:3

    Topics: Amino Acids; Animals; Arginine; Ascorbic Acid; Carbohydrates; Glucose; Glycine; In Vitro Techniques;

2010
Involvement of endogenous hydrogen sulfide in cigarette smoke-induced changes in airway responsiveness and inflammation of rat lung.
    Cytokine, 2011, Volume: 53, Issue:3

    Topics: Acetylcholine; Alkynes; Animals; Cystathionine gamma-Lyase; Dose-Response Relationship, Drug; Enzyme

2011
Novel expression of a functional glycine receptor chloride channel that attenuates contraction in airway smooth muscle.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:5

    Topics: Acetylcholine; Animals; Cells, Cultured; Cesium; Chlorides; Electrophysiology; Glycine; Guinea Pigs;

2011
Sivelestat relaxes vascular smooth muscle contraction in human gastric arteries.
    Journal of physiology and biochemistry, 2011, Volume: 67, Issue:4

    Topics: Aged; Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Glycine; Hemodynamics; Huma

2011
Identification of minimal neuronal networks involved in flexor-extensor alternation in the mammalian spinal cord.
    Neuron, 2011, Sep-22, Volume: 71, Issue:6

    Topics: Action Potentials; Animals; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Glyci

2011
The effect of the Asp175Asn and Glu180Gly TPM1 mutations on actin-myosin interaction during the ATPase cycle.
    Biochimica et biophysica acta, 2012, Volume: 1824, Issue:2

    Topics: Actins; Actomyosin; Adenosine Triphosphatases; Amino Acid Substitution; Animals; Asparagine; Asparti

2012
The smooth muscle relaxant effect of hydrogen sulphide in vitro: evidence for a physiological role to control intestinal contractility.
    British journal of pharmacology, 2002, Volume: 137, Issue:2

    Topics: Alanine; Alkynes; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Glycine; Guinea P

2002
PRQFVamide, a novel pentapeptide identified from the CNS and gut of Aplysia.
    Journal of neurophysiology, 2003, Volume: 89, Issue:6

    Topics: Amides; Amino Acid Sequence; Animals; Aplysia; Arginine; Blood Vessels; Blotting, Northern; Central

2003
[Effect of glutamic acid, asparagine, glycocoll and alanine on the contractile function of the skeletal muscle and on its sensitization to potassium ions].
    Biulleten' eksperimental'noi biologii i meditsiny, 1962, Volume: 3

    Topics: Alanine; Asparagine; Glutamates; Glutamic Acid; Glycine; Ions; Muscle Contraction; Muscle, Skeletal;

1962
Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity.
    Structure (London, England : 1993), 2003, Volume: 11, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amides; Amino Acid Sequence;

2003
Effects of glycine and proline on the calcium activation properties of skinned muscle fibre segments from crayfish and rat.
    Journal of muscle research and cell motility, 2003, Volume: 24, Issue:7

    Topics: Animals; Astacoidea; Calcium; Glycine; Male; Muscle Contraction; Muscle Fibers, Fast-Twitch; Muscle

2003
Pacemaker activity in hydra is modulated by glycine receptor ligands.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2004, Volume: 138, Issue:2

    Topics: Animals; Biological Clocks; Carboxylic Acids; Glycine; Glycine Agents; Hydra; Indoles; Ligands; Memb

2004
The Arg389Gly beta1-adrenoceptor gene polymorphism determines contractile response to catecholamines.
    Pharmacogenetics, 2004, Volume: 14, Issue:11

    Topics: Arginine; Catecholamines; Echocardiography; Glycine; Heart Atria; Humans; In Vitro Techniques; Male;

2004
Effects of the mutation R145G in human cardiac troponin I on the kinetics of the contraction-relaxation cycle in isolated cardiac myofibrils.
    The Journal of physiology, 2005, Apr-15, Volume: 564, Issue:Pt 2

    Topics: Animals; Arginine; Glycine; Humans; Kinetics; Mice; Mice, Transgenic; Muscle Contraction; Muscle Rel

2005
Activation of the rostral pontine reticular formation increases the spinal glycine level and inhibits bladder contraction in rats.
    The Journal of urology, 2005, Volume: 173, Issue:5

    Topics: Animals; Benzilates; Carbachol; Flavoxate; Glycine; Muscle Contraction; Rats; Rats, Sprague-Dawley;

2005
Effect of glycine on recovery of bladder smooth muscle contractility after acute urinary retention in rats.
    BJU international, 2005, Volume: 96, Issue:9

    Topics: Animals; Apoptosis; Blotting, Western; Female; Glycine; Glycine Agents; Muscle Contraction; Muscle,

2005
Epithelium-dependent and -independent inhibitory effects of sivelestat, a neutrophil elastase inhibitor, on substance P-induced contraction of airway smooth muscle in lipopolysaccharide-treated guinea-pigs.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2005, Volume: 41, Issue:5

    Topics: Animals; Bronchi; Glycine; Guinea Pigs; In Vitro Techniques; Indomethacin; Leukocyte Elastase; Lipop

2005
New 2',6'-dimethyl-L-tyrosine (Dmt) opioid peptidomimetics based on the Aba-Gly scaffold. Development of unique mu-opioid receptor ligands.
    Journal of medicinal chemistry, 2006, Jun-29, Volume: 49, Issue:13

    Topics: Analgesics, Opioid; Animals; Benzazepines; Glycine; Guinea Pigs; In Vitro Techniques; Ligands; Molec

2006
Mutation of a conserved glycine in the SH1-SH2 helix affects the load-dependent kinetics of myosin.
    Biophysical journal, 2007, Mar-01, Volume: 92, Issue:5

    Topics: Actins; Adenosine Triphosphate; Amino Acid Substitution; Animals; Glycine; Models, Molecular; Muscle

2007
Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2007, Volume: 21, Issue:3

    Topics: Actins; Amino Acid Substitution; Animals; Arginine; Arthrogryposis; Calcium; Glycine; Humans; Muscle

2007
Role of spinal metabotropic glutamate receptors in regulation of lower urinary tract function in the decerebrate unanesthetized rat.
    Neuroscience letters, 2007, Jun-08, Volume: 420, Issue:1

    Topics: Anesthesia; Animals; Decerebrate State; Dose-Response Relationship, Drug; Electromyography; Female;

2007
alpha,alpha-Cyclopentaneglycine dipeptides capped with biaryls as tachykinin NK(2) receptor antagonists.
    ChemMedChem, 2008, Volume: 3, Issue:7

    Topics: Animals; Binding, Competitive; Biphenyl Compounds; Cell Membrane; Colon; Cyclopentanes; Dipeptides;

2008
Adverse effects of artificial buffers on contractile responses of arterial and venous smooth muscle.
    British journal of pharmacology, 1980, Volume: 69, Issue:2

    Topics: Alkanesulfonates; Angiotensin II; Animals; Buffers; Calcium; Epinephrine; Glycine; HEPES; In Vitro T

1980
Involvement of central GABA receptors in the regulation of the urinary bladder function of anaesthetized rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 314, Issue:2

    Topics: Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Glycine; Levodopa; Male; Muscimol; Muscle C

1980
Modulation of arterial muscle contraction in Aplysia by glycine and neuron R14.
    Brain research, 1981, Mar-02, Volume: 207, Issue:2

    Topics: Animals; Aorta; Aplysia; Ganglia; Glycine; Ion Channels; Motor Neurons; Muscle Contraction; Muscle,

1981
Purification and sequence analysis of bioactive atrial peptides (atriopeptins).
    Science (New York, N.Y.), 1984, Jan-06, Volume: 223, Issue:4631

    Topics: Amino Acid Sequence; Animals; Arginine; Chromatography, High Pressure Liquid; Chromatography, Ion Ex

1984
Influences of glycine and neuron R14 on contraction of the anterior aorta of Aplysia.
    The Japanese journal of physiology, 1984, Volume: 34, Issue:4

    Topics: Animals; Aorta; Aplysia; Biomechanical Phenomena; Electrophysiology; Ganglia; Glycine; Muscle Contra

1984
AMP deamination and IMP reamination in working skeletal muscle.
    The American journal of physiology, 1980, Volume: 239, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Ammonia; Animals; Formaldehy

1980
The topographical basis and frequency-dependence in the effect of different compounds on neurogenic contractions of the guinea-pig ileum.
    General physiology and biophysics, 1993, Volume: 12, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
The role of glycine (residue 89) in the central helix of EF-hand protein troponin-C exposed following amino-terminal alpha-helix deletion.
    Protein science : a publication of the Protein Society, 1994, Volume: 3, Issue:11

    Topics: Amino Acid Sequence; Animals; Base Sequence; Calcium; Circular Dichroism; Edetic Acid; Glycine; Mole

1994
Regulation of scallop myosin by the regulatory light chain depends on a single glycine residue.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Sep-13, Volume: 91, Issue:19

    Topics: Actins; Amino Acid Sequence; Animals; Calcium; Chickens; Glycine; Molecular Sequence Data; Mollusca;

1994
Human sodium channel myotonia: slowed channel inactivation due to substitutions for a glycine within the III-IV linker.
    The Journal of physiology, 1993, Volume: 470

    Topics: Action Potentials; Amino Acid Sequence; DNA, Single-Stranded; Electrophysiology; Exons; Glycine; Hum

1993
Glycinergic inhibition in the turtle spinal cord regulates the intensity and pattern of fictive flexion reflex motor output.
    Neuroscience letters, 1996, Feb-23, Volume: 205, Issue:2

    Topics: Animals; Efferent Pathways; Evoked Potentials, Motor; gamma-Aminobutyric Acid; Glycine; Motor Neuron

1996
Effect of some amino acids on the rectal irritation caused by sodium caprate in conscious rats.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:3

    Topics: Amino Acids; Animals; Arginine; Decanoic Acids; Fluoresceins; Fluorescent Dyes; Glycine; Intestinal

1996
Exogenous substrates as energy source for the contractile activity of the isolated rat tail artery.
    Revista espanola de fisiologia, 1996, Volume: 52, Issue:3

    Topics: Animals; Arteries; Carnitine O-Palmitoyltransferase; Culture Media; Deoxyglucose; Energy Metabolism;

1996
Pharmacological profile of TH-142177, a novel orally active AT1-receptor antagonist.
    Fundamental & clinical pharmacology, 1997, Volume: 11, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Blood Pressure; Cattle; Cerebellum

1997
Gly341Arg mutation indicating malignant hyperthermia susceptibility: specific cause of chronically elevated serum creatine kinase activity.
    Journal of the neurological sciences, 1998, Jan-21, Volume: 154, Issue:1

    Topics: Adult; Aged; Amino Acid Substitution; Arginine; Child; Creatine Kinase; Female; Glycine; Humans; Mal

1998
When are class I metabotropic glutamate receptors necessary for long-term potentiation?
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Aug-15, Volume: 18, Issue:16

    Topics: Animals; Benzoates; Calcium; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials;

1998
Nitric oxide-mediated relaxation induced by bradykinin in the isolated mouse trachea.
    European journal of pharmacology, 1998, Jul-10, Volume: 352, Issue:2-3

    Topics: Animals; Aspirin; Bradykinin; Carbachol; Female; Glycine; In Vitro Techniques; Male; Mice; Muscle Co

1998
Glycine preserves function and decreases necrosis in skeletal muscle undergoing ischemia and reperfusion injury.
    Surgery, 2001, Volume: 129, Issue:2

    Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Dogs; Glycine; Infusions, Intra-Arterial; I

2001
[The synthesis and pharmacologic properties of N-alkylester homologs of d,1-2-phenylglycine].
    Die Pharmazie, 1978, Volume: 33, Issue:11

    Topics: Animals; Blood Pressure; Cats; Drug Interactions; Glycine; Guinea Pigs; Heart Rate; Histamine H1 Ant

1978
[Stimulating effects of alanine and glycine on guinea-pig taenia coli (author's transl)].
    Nihon Heikatsukin Gakkai zasshi, 1979, Volume: 15, Issue:1

    Topics: Action Potentials; Alanine; Animals; Atropine; Calcium; Chlorine; Colon; Dose-Response Relationship,

1979
Neurochemical aspects of post-tetanic potentiation of monosynaptic reflexes in the cat spinal cord. I. Analysis of amino acids at maximum of potentiation.
    Neurobiology, 1975, Volume: 5, Issue:1

    Topics: Action Potentials; Alanine; Amino Acids; Animals; Aspartic Acid; Cats; Electric Stimulation; Female;

1975
Effect of release of endogenous gastrin on myoelectrical and mechanical activity of isolated canine stomach.
    Pharmacology, 1975, Volume: 13, Issue:1

    Topics: Acetylcholine; Action Potentials; Animals; Dogs; Gastrins; Glycine; Hydrogen-Ion Concentration; Musc

1975
Sites of action of D2O in intact and skinned crayfish muscle fibers.
    The Journal of membrane biology, 1975, Dec-04, Volume: 24, Issue:3-4

    Topics: Animals; Astacoidea; Caffeine; Calcium; Deuterium; Egtazic Acid; Glycine; Manganese; Membrane Potent

1975
[Intercentral relations in rat spinal cord with local depression of the inhibitory processes].
    Neirofiziologiia = Neurophysiology, 1975, Volume: 7, Issue:3

    Topics: Animals; Electromyography; Electrophysiology; Evoked Potentials; Glycine; Hindlimb; Lumbosacral Plex

1975
[The synthesis and biological activity of some structural analogs of carbon and silicon compounds].
    Die Pharmazie, 1975, Volume: 30, Issue:12

    Topics: Acetylcholine; Amino Acids; Animals; Glycine; Guinea Pigs; Ileum; In Vitro Techniques; Lethal Dose 5

1975
Induction of feeding by 7-chlorokynurenic acid, a strychnine-insensitive glycine binding site antagonist.
    Brain research, 1992, Feb-14, Volume: 572, Issue:1-2

    Topics: Analysis of Variance; Animals; Ataxia; Dose-Response Relationship, Drug; Feeding Behavior; Glycine;

1992
Analogs of the delta opioid receptor selective cyclic peptide [2-D-penicillamine,5-D-penicillamine]-enkephalin: 2',6'-dimethyltyrosine and Gly3-Phe4 amide bond isostere substitutions.
    Journal of medicinal chemistry, 1992, Aug-07, Volume: 35, Issue:16

    Topics: Amides; Amino Acid Sequence; Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; G

1992
Endothelium-dependent and -independent contractions to glycine in isolated vascular smooth muscles.
    Japanese journal of pharmacology, 1992, Volume: 58 Suppl 2

    Topics: Animals; Aorta, Thoracic; Chickens; Endothelium, Vascular; Glycine; In Vitro Techniques; Muscle Cont

1992
N-methyl-D-aspartate receptor-mediated contractions of the guinea pig ileum longitudinal muscle/myenteric plexus preparation: modulation by phencyclidine and glycine receptors.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:2

    Topics: Animals; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic

1991
Thiokynurenates: a new group of antagonists of the glycine modulatory site of the NMDA receptor.
    European journal of pharmacology, 1991, Jun-25, Volume: 199, Issue:2

    Topics: Animals; Binding Sites; Cerebral Cortex; Chlorine; Fluorine; Glutamates; Glutamic Acid; Glycine; Gui

1991
Non-amidated forms of VIP (glycine-extended VIP and VIP-free acid) have full bioactivity on smooth muscle.
    Regulatory peptides, 1989, Volume: 26, Issue:3

    Topics: Animals; Fallopian Tubes; Female; Glycine; Humans; Muscle Contraction; Muscle, Smooth; Rats; Rats, I

1989
Intracisternal glycine activates the micturition reflex in urethane-anaesthetized rats.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:7

    Topics: Anesthesia; Animals; Atropine; Bicuculline; Cisterna Magna; Glycine; Haloperidol; Injections; Male;

1985
Agonists, antagonists and modulators of excitatory amino acid receptors in the guinea-pig myenteric plexus.
    British journal of pharmacology, 1988, Volume: 95, Issue:4

    Topics: Animals; Glutamates; Glutamic Acid; Glycine; Guinea Pigs; In Vitro Techniques; Magnesium; Male; Musc

1988
Suppression of contractile force in muscle fibers by antibody to myosin subfragment 2.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:6

    Topics: Adenosine Triphosphatases; Animals; Antibodies; Chickens; Glycine; Immunoglobulin Fab Fragments; Mus

1988
Pharmacological effects of haem biosynthetic intermediates in isolated intestinal preparations.
    European journal of pharmacology, 1987, Feb-24, Volume: 134, Issue:3

    Topics: Aminolevulinic Acid; Animals; Colon; Coproporphyrins; Female; Glycine; Heme; Hemin; In Vitro Techniq

1987
Effects of some antiprotozoal diamidines on voluntary muscle.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 198, Issue:2

    Topics: Acetates; Amidines; Anilides; Animals; Antiprotozoal Agents; Chickens; Diaphragm; Electric Stimulati

1972
Antagonism of the trypanocide, berenil, and the nematocide, morantel, by tubocurarine.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 280, Issue:1

    Topics: Acetylcholine; Amidines; Animals; Antinematodal Agents; Anura; Glycine; Muscle Contraction; Pyrimidi

1973
II. Pharmacology of angiotensin antagonists.
    Canadian journal of physiology and pharmacology, 1973, Volume: 51, Issue:2

    Topics: Angiotensin II; Animals; Asparagine; Dose-Response Relationship, Drug; Glycine; In Vitro Techniques;

1973
Characterization of angiotensin receptors in vascular and intestinal smooth muscles.
    British journal of pharmacology, 1973, Volume: 48, Issue:2

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Colon; Dose-Response Relationship, Drug; G

1973
Role of the N-terminal amino acid for the biological activities of angiotensin and inhibitory analogues.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:1

    Topics: Amino Acids; Aminopeptidases; Angiotensin II; Animals; Aorta; Aspartic Acid; Blood Pressure; Chromat

1974
Study of pituitary hormone analogs for their inhibitory properties and resistance to carboxamidopeptidases: (9-L-proline)oxytocin, (9-L-glutamic acid)oxytocin, and (8-L-lysine,9-glycine methylamide)oxytocin.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:12

    Topics: Animals; Anura; Blood Pressure; Carbon Radioisotopes; Chickens; Diuresis; Female; Glutamates; Glycin

1974
Synthesis and some pharmacological properties of (1-deamino,9-thioglycine)oxytocin.
    Journal of the American Chemical Society, 1973, Aug-22, Volume: 95, Issue:17

    Topics: Animals; Chickens; Deamination; Female; Glycine; Methods; Muscle Contraction; Oxytocin; Rats; Struct

1973
Some ionic factors in amino acid transport in contracting rat diaphragm.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Oct-01, Volume: 144, Issue:1

    Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Carbon Radioisotopes; Dia

1973
Corneal opacity, microphthalmia, mental retardation, microcephaly and generalized muscular spasticity associated with hyperglycinemia.
    Clinical genetics, 1974, Volume: 5, Issue:1

    Topics: Alkaline Phosphatase; Calcium; Cerebral Palsy; Chromosomes; Consanguinity; Corneal Opacity; Female;

1974
Inhibition and excitation of sacral parasympathetic neurons by visceral and cutaneous stimuli in the cat.
    Brain research, 1971, Oct-29, Volume: 33, Issue:2

    Topics: Action Potentials; Aminobutyrates; Animals; Cats; Colon; Electric Stimulation; Female; Ganglia, Auto

1971
A fragment of the third component of human complement with anaphylatoxin activity.
    Biochemistry, 1971, Mar-30, Volume: 10, Issue:7

    Topics: Amino Acids; Animals; Arginine; Autoanalysis; Carboxypeptidases; Chromatography, Gel; Complement Sys

1971