glycine has been researched along with Motor Neuron Disease in 10 studies
Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amyotrophic lateral sclerosis (ALS) is a devastating disease characterized by upper and lower motor neuron damage." | 1.36 | Familial amyotrophic lateral sclerosis with a novel G85S mutation of superoxide dismutase 1 gene: clinical features of lower motor neuron disease. ( Hirayama, T; Ikeda, K; Ito, H; Iwasaki, Y; Kano, O; Kawabe, K; Nakamura, Y; Sobue, G; Takazawa, T; Tanaka, F; Yoshii, Y, 2010) |
| "Amyotrophic lateral sclerosis (ALS), a multifactorial disease characterized by diffuse motor neuron degeneration, has proven to be a difficult target for stem cell therapy." | 1.32 | Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation. ( Chen, N; Davis, CD; Garbuzova-Davis, S; Hudson, JE; Justen, EB; Lane, JC; Sanberg, PR; Saporta, S; Willing, AE; Zigova, T, 2003) |
| "One female patient with amyotrophic lateral sclerosis (ALS) was heterozygous for G12R mutation." | 1.32 | [Peculiarities of sporadic motor neuron disease associated with D90A and G12R mutations in Russian population]. ( Alekhin, AV; Brusov, OS; Karakhan, VB; Kondrat'eva, EA; Levitskaia, NI; Levitskiĭ, GN; Limborskaia, SA; Lysko, AI; Serdiuk, AV; Shadrina, MI; Skvortsova, VI; Slominskiĭ, PA, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soares, DC | 1 |
| Barlow, PN | 1 |
| Porteous, DJ | 1 |
| Devon, RS | 1 |
| Takazawa, T | 1 |
| Ikeda, K | 1 |
| Hirayama, T | 1 |
| Kawabe, K | 1 |
| Nakamura, Y | 1 |
| Ito, H | 1 |
| Kano, O | 1 |
| Yoshii, Y | 1 |
| Tanaka, F | 1 |
| Sobue, G | 1 |
| Iwasaki, Y | 1 |
| Borghese, CM | 1 |
| Blednov, YA | 1 |
| Quan, Y | 1 |
| Iyer, SV | 1 |
| Xiong, W | 1 |
| Mihic, SJ | 1 |
| Zhang, L | 1 |
| Lovinger, DM | 1 |
| Trudell, JR | 1 |
| Homanics, GE | 1 |
| Harris, RA | 1 |
| Garbuzova-Davis, S | 1 |
| Willing, AE | 1 |
| Zigova, T | 1 |
| Saporta, S | 1 |
| Justen, EB | 1 |
| Lane, JC | 1 |
| Hudson, JE | 1 |
| Chen, N | 1 |
| Davis, CD | 1 |
| Sanberg, PR | 1 |
| Skvortsova, VI | 1 |
| Limborskaia, SA | 1 |
| Slominskiĭ, PA | 1 |
| Levitskiĭ, GN | 1 |
| Levitskaia, NI | 1 |
| Shadrina, MI | 1 |
| Kondrat'eva, EA | 1 |
| Brusov, OS | 1 |
| Lysko, AI | 1 |
| Karakhan, VB | 1 |
| Alekhin, AV | 1 |
| Serdiuk, AV | 1 |
| Cheroni, C | 1 |
| Peviani, M | 1 |
| Cascio, P | 1 |
| Debiasi, S | 1 |
| Monti, C | 1 |
| Bendotti, C | 1 |
| Virgo, L | 1 |
| de Belleroche, JS | 1 |
| Khan, JK | 1 |
| Kuo, YH | 1 |
| Haque, A | 1 |
| Lambein, F | 1 |
| Lane, RJ | 1 |
| Bandopadhyay, R | 1 |
| de Belleroche, J | 1 |
| Rodríguez-Ithurralde, D | 1 |
| Olivera, S | 1 |
| Vincent, O | 1 |
| Maruri, A | 1 |
10 other studies available for glycine and Motor Neuron Disease
| Article | Year |
|---|---|
An interrupted beta-propeller and protein disorder: structural bioinformatics insights into the N-terminus of alsin.
Topics: Amino Acid Sequence; Cell Cycle Proteins; Cysteine; Glycine; Guanine Nucleotide Exchange Factors; Hu | 2009 |
Familial amyotrophic lateral sclerosis with a novel G85S mutation of superoxide dismutase 1 gene: clinical features of lower motor neuron disease.
Topics: Adult; Amyotrophic Lateral Sclerosis; Fatal Outcome; Female; Glycine; Humans; Male; Motor Neuron Dis | 2010 |
Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols.
Topics: Alcohols; Amino Acid Substitution; Animals; Binding, Competitive; Brain Stem; Cells, Cultured; Drug | 2012 |
Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation.
Topics: Alanine; Animals; Cord Blood Stem Cell Transplantation; Disease Models, Animal; Disease Progression; | 2003 |
[Peculiarities of sporadic motor neuron disease associated with D90A and G12R mutations in Russian population].
Topics: Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Arginine; Copper; Disease Progression; Elect | 2003 |
Accumulation of human SOD1 and ubiquitinated deposits in the spinal cord of SOD1G93A mice during motor neuron disease progression correlates with a decrease of proteasome.
Topics: Alanine; Amino Acid Substitution; Animals; Female; Glycine; Humans; Mice; Mice, Inbred C57BL; Mice, | 2005 |
Differential changes in gene expression in motor neurone disease.
Topics: Amino Acid Oxidoreductases; Amino Acid Transport Systems, Neutral; Carrier Proteins; Choline O-Acety | 1994 |
Inhibitory and excitatory amino acids in cerebrospinal fluid of neurolathyrism patients, a highly prevalent motorneurone disease.
Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Eating; Excitatory Amino Acids; Fabaceae; Glutamic | 1995 |
Abnormal glycine metabolism in motor neurone disease: studies on plasma and cerebrospinal fluid.
Topics: Amino Acids; Female; Glycine; Humans; Male; Middle Aged; Motor Neuron Disease; Single-Blind Method | 1993 |
In vivo and in vitro studies of glycine- and glutamate-evoked acetylcholinesterase release from spinal motor neurones: implications for amyotrophic lateral sclerosis/motor neurone disease pathogenesis.
Topics: Acetylcholinesterase; Amyotrophic Lateral Sclerosis; Animals; Calcium; Glutamic Acid; Glycine; Histo | 1997 |