glycine has been researched along with MELAS Syndrome in 4 studies
MELAS Syndrome: A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The MELAS has been related to mutation A3243G in most cases, but some other mitochondrial DNA mutations were described in the background of this syndrome as well." | 1.37 | A8344G mutation of the mitochondrial DNA with typical mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome. ( Gál, A; Lukács, T; Molnár, MJ; Reményi, V; Semjén, J; Valikovics, A; Vastagh, I, 2011) |
| "Cerebral focal lesions in MELAS might have a metabolic nature and several pathogenetic mechanisms might be involved in the genesis of stroke-like episodes when there is a local increased ATP demand." | 1.32 | MELAS: clinical phenotype and morphological brain abnormalities. ( Bartolomei, L; Cavallaro, T; Grauso, M; Morelli, L; Piscioli, F; Rizzuto, N; Simonati, A; Sparaco, M, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikawa, M | 1 |
| Arakawa, K | 1 |
| Hamano, T | 1 |
| Nagata, M | 1 |
| Nakamoto, Y | 1 |
| Kuriyama, M | 1 |
| Koga, Y | 1 |
| Yoneda, M | 1 |
| Vastagh, I | 1 |
| Gál, A | 1 |
| Reményi, V | 1 |
| Semjén, J | 1 |
| Lukács, T | 1 |
| Valikovics, A | 1 |
| Molnár, MJ | 1 |
| Latvala, T | 1 |
| Mustonen, E | 1 |
| Uusitalo, R | 1 |
| Majamaa, K | 1 |
| Sparaco, M | 1 |
| Simonati, A | 1 |
| Cavallaro, T | 1 |
| Bartolomei, L | 1 |
| Grauso, M | 1 |
| Piscioli, F | 1 |
| Morelli, L | 1 |
| Rizzuto, N | 1 |
4 other studies available for glycine and MELAS Syndrome
| Article | Year |
|---|---|
Evaluation of systemic redox states in patients carrying the MELAS A3243G mutation in mitochondrial DNA.
Topics: Adolescent; Adult; Alanine; Antioxidants; DNA, Mitochondrial; Female; Glycine; Humans; Hydrogen Pero | 2012 |
A8344G mutation of the mitochondrial DNA with typical mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome.
Topics: Acidosis, Lactic; Adult; Alanine; Brain Ischemia; DNA, Mitochondrial; Glycine; Humans; Male; MELAS S | 2011 |
Pigmentary retinopathy in patients with the MELAS mutation 3243A-->G in mitochondrial DNA.
Topics: Adult; Aged; Alanine; DNA, Mitochondrial; Eye Diseases; Female; Glycine; Humans; Male; MELAS Syndrom | 2002 |
MELAS: clinical phenotype and morphological brain abnormalities.
Topics: Adenosine Triphosphatases; Adult; Alanine; Brain; Carboxylic Ester Hydrolases; Child; DNA, Mitochond | 2003 |