glycine has been researched along with Liver Cirrhosis, Biliary in 9 studies
Liver Cirrhosis, Biliary: FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cholangitis involves the destruction of small intra-hepatic bile ducts and decreased bile secretion. Secondary biliary cholangitis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ursodeoxycholic acid (UDCA) exerts anticholestatic, antifibrotic and antiproliferative effects in primary biliary cirrhosis (PBC) via mechanisms not yet fully understood." | 9.16 | Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health. ( Bastiaansen, BA; Beuers, U; Dilger, K; Hohenester, S; Rust, C; Schaap, FG; Winkler-Budenhofer, U, 2012) |
| "We have applied a specific and accurate high pressure liquid chromatographic technique to determine fasting serum glycine and taurine conjugates of individual bile acids in patients with primary biliary cirrhosis before and during ursodeoxycholic acid therapy." | 7.67 | Bile acid glycine and taurine conjugates in serum of patients with primary biliary cirrhosis: effect of ursodeoxycholic treatment. ( Chazouilleres, O; Chretien, Y; Gherardt, MF; Labbe, D; Myara, A; Poupon, R; Trivin, F, 1989) |
| "Ursodeoxycholic acid (UDCA) exerts anticholestatic, antifibrotic and antiproliferative effects in primary biliary cirrhosis (PBC) via mechanisms not yet fully understood." | 5.16 | Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health. ( Bastiaansen, BA; Beuers, U; Dilger, K; Hohenester, S; Rust, C; Schaap, FG; Winkler-Budenhofer, U, 2012) |
| "The concentration of total bile acids, taurine and glycine conjugates of primary bile acids was elevated in both patients with primary biliary cirrhosis and primary sclerosing cholangitis when compared to non-cholestatic donors." | 3.78 | Metabolomic profiling of 17 bile acids in serum from patients with primary biliary cirrhosis and primary sclerosing cholangitis: a pilot study. ( Barbier, O; Białek, A; Caron, P; Heathcote, J; Milkiewicz, P; Straka, RJ; Trottier, J, 2012) |
| "We have applied a specific and accurate high pressure liquid chromatographic technique to determine fasting serum glycine and taurine conjugates of individual bile acids in patients with primary biliary cirrhosis before and during ursodeoxycholic acid therapy." | 3.67 | Bile acid glycine and taurine conjugates in serum of patients with primary biliary cirrhosis: effect of ursodeoxycholic treatment. ( Chazouilleres, O; Chretien, Y; Gherardt, MF; Labbe, D; Myara, A; Poupon, R; Trivin, F, 1989) |
| "While drug-related biliary cirrhosis is rarely fatal, this case presented an unusually rapid course of fatal biliary cirrhosis." | 1.29 | A case of drug-induced ductopenia resulting in fatal biliary cirrhosis. ( Ishii, M; Miura, M; Miyazaki, Y; Takahashi, T; Toyota, T; Ueno, Y; Yamamoto, T, 1993) |
| "The bilirubin clearance was impaired to 30-50% of the normal value in most cases of hepatobiliary disease and also in primary haemolysis." | 1.28 | The origins and kinetics of bilirubin in dogs with hepatobiliary and haemolytic diseases. ( Fevery, J; Rothuizen, J; van den Brom, WE, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, D | 2 |
| Li, G | 1 |
| Shi, W | 1 |
| Wang, H | 1 |
| Zhang, Q | 1 |
| Shen, M | 1 |
| Huang, X | 1 |
| Lin, H | 1 |
| Pastor, CM | 1 |
| Trottier, J | 1 |
| Białek, A | 1 |
| Caron, P | 1 |
| Straka, RJ | 1 |
| Heathcote, J | 1 |
| Milkiewicz, P | 1 |
| Barbier, O | 1 |
| Dilger, K | 1 |
| Hohenester, S | 1 |
| Winkler-Budenhofer, U | 1 |
| Bastiaansen, BA | 1 |
| Schaap, FG | 1 |
| Rust, C | 1 |
| Beuers, U | 1 |
| Ito, S | 1 |
| Xu, Y | 1 |
| Keyser, AJ | 1 |
| Peters, RL | 1 |
| Ishii, M | 1 |
| Miyazaki, Y | 1 |
| Yamamoto, T | 1 |
| Miura, M | 1 |
| Ueno, Y | 1 |
| Takahashi, T | 1 |
| Toyota, T | 1 |
| Rothuizen, J | 1 |
| van den Brom, WE | 1 |
| Fevery, J | 1 |
| Chretien, Y | 1 |
| Poupon, R | 1 |
| Gherardt, MF | 1 |
| Chazouilleres, O | 1 |
| Labbe, D | 1 |
| Myara, A | 1 |
| Trivin, F | 1 |
| Murphy, GM | 1 |
| Ross, A | 1 |
| Billing, BH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00529009] | Phase 1 | 0 participants | Interventional | 2007-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for glycine and Liver Cirrhosis, Biliary
| Article | Year |
|---|---|
Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health.
Topics: Adult; Bile Acids and Salts; Biliary Tract; Carrier Proteins; Cholagogues and Choleretics; Cholestas | 2012 |
8 other studies available for glycine and Liver Cirrhosis, Biliary
| Article | Year |
|---|---|
Quantitative Detection of 15 Serum Bile Acid Metabolic Products by LC/MS/MS in the Diagnosis of Primary Biliary Cholangitis.
Topics: Bile Acids and Salts; Biomarkers; Chromatography, Liquid; Glycine; Humans; Liver Cirrhosis, Biliary; | 2023 |
Isolated Perfused Rat Livers to Quantify the Pharmacokinetics and Concentrations of Gd-BOPTA.
Topics: Aniline Compounds; Animals; ATP-Binding Cassette Transporters; Bile Canaliculi; Biological Transport | 2018 |
Metabolomic profiling of 17 bile acids in serum from patients with primary biliary cirrhosis and primary sclerosing cholangitis: a pilot study.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Cholangit | 2012 |
Histochemical demonstration of guanase in human liver with guanine in bicine buffer as substrate.
Topics: Adult; Aminohydrolases; Buffers; Female; Glycine; Guanine; Guanine Deaminase; Histocytochemistry; Hu | 1984 |
A case of drug-induced ductopenia resulting in fatal biliary cirrhosis.
Topics: Bile Duct Diseases; Bile Ducts, Intrahepatic; Cysteine; Drug Combinations; Female; Glycine; Glycyrrh | 1993 |
The origins and kinetics of bilirubin in dogs with hepatobiliary and haemolytic diseases.
Topics: Anemia, Hemolytic; Animals; Bilirubin; Carbon Radioisotopes; Dogs; Erythrocytes; Female; Glycine; He | 1992 |
Bile acid glycine and taurine conjugates in serum of patients with primary biliary cirrhosis: effect of ursodeoxycholic treatment.
Topics: Bile Acids and Salts; Chromatography, High Pressure Liquid; Deoxycholic Acid; Female; Glycine; Human | 1989 |
Serum bile acids in primary biliary cirrhosis.
Topics: Bile Acids and Salts; Cholestasis; Cholestyramine Resin; Glycine; Humans; Hydroxylation; Liver Cirrh | 1972 |