glycine has been researched along with Leukemia, Monocytic, Acute in 4 studies
Leukemia, Monocytic, Acute: An acute myeloid leukemia in which 80% or more of the leukemic cells are of monocytic lineage including monoblasts, promonocytes, and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tosedostat is a novel oral aminopeptidase inhibitor with clinical activity in a previous phase 1-2 study in elderly patients with relapsed or refractory acute myeloid leukaemia (AML)." | 2.78 | Two dosing regimens of tosedostat in elderly patients with relapsed or refractory acute myeloid leukaemia (OPAL): a randomised open-label phase 2 study. ( Advani, AS; Charman, A; Cortes, J; Feldman, E; Kantarjian, H; Rizzieri, D; Spruyt, R; Toal, M; Yee, K, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cortes, J | 1 |
| Feldman, E | 1 |
| Yee, K | 1 |
| Rizzieri, D | 1 |
| Advani, AS | 1 |
| Charman, A | 1 |
| Spruyt, R | 1 |
| Toal, M | 1 |
| Kantarjian, H | 1 |
| Lapidot, A | 1 |
| Nissim, I | 1 |
| Shaklai, M | 1 |
| Samuel, R | 1 |
| Liberman, UA | 1 |
| Walters, TR | 1 |
| Welland, FH | 1 |
| Gribble, TJ | 1 |
| Schwartz, HC | 1 |
| Dimitrov, NV | 1 |
| Hansz, J | 1 |
| Toth, MA | 1 |
| Bartolotta, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The OPAL Study: A Phase II Study to Evaluate the Efficacy, Safety and Tolerability of Tosedostat (CHR-2797) in Elderly Subjects With Treatment Refractory or Relapsed Acute Myeloid Leukemia[NCT00780598] | Phase 2 | 76 participants (Actual) | Interventional | 2009-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for glycine and Leukemia, Monocytic, Acute
| Article | Year |
|---|---|
Two dosing regimens of tosedostat in elderly patients with relapsed or refractory acute myeloid leukaemia (OPAL): a randomised open-label phase 2 study.
Topics: Aged; Aged, 80 and over; Anemia, Refractory; Cytarabine; Disease-Free Survival; Female; Glycine; Hum | 2013 |
3 other studies available for glycine and Leukemia, Monocytic, Acute
| Article | Year |
|---|---|
Glycine pools and turnover rates in leukaemia patients measured with [15N]glycine.
Topics: Female; Glycine; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemi | 1984 |
Biosynthesis of heme in leukemic leukocytes.
Topics: Adult; Animals; Glycine; Heme; Humans; Iron Isotopes; Leukemia; Leukemia, Lymphoid; Leukemia, Monocy | 1967 |
Serine and aspartic acid metabolism in leukemic leukocytes: correlation to effectiveness of therapy.
Topics: Adult; Aged; Aspartic Acid; Blood Proteins; Carbon Dioxide; Carbon Isotopes; Female; Glycine; Humans | 1971 |