glycine has been researched along with Ischemia in 83 studies
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effects of glycine on apoptosis in murine cardiomyocyte suffering from ischemia and hypoxia." | 7.74 | [Effects of glycine on apoptosis in murine cardiomyocyte suffering from ischemia and hypoxia]. ( Dang, YM; Huang, YS; Song, HP; Zhang, DX; Zhang, Q; Zhou, JL, 2008) |
| " In the present study, we examined the neuroprotective potency of the selective mGluR5 agonist, (R,S)-2-chloro-5-hydroxyphenylglycine (CHPG), in endothelin-1(ET-1)-induced focal ischemia in rats." | 7.74 | No improvement of functional and histological outcome after application of the metabotropic glutamate receptor 5 agonist CHPG in a model of endothelin-1-induced focal ischemia in rats. ( Henrich-Noack, P; Reymann, KG; Riek-Burchardt, M, 2007) |
| "The role of glycine has not been investigated in lung ischemia-reperfusion injury after cold preservation." | 7.72 | Glycine ameliorates lung reperfusion injury after cold preservation in an ex vivo rat lung model. ( Fukuse, T; Hasegawa, S; Ikeyama, K; Mizutani, Y; Omasa, M; Toyokuni, S; Wada, H; Yoshida, H, 2003) |
| "Glycine (GLY) is a neutral amino acid that has been shown to be cytoprotective in the kidneys of dogs and rabbits undergoing ischemia-reperfusion injury." | 7.71 | Glycine preserves function and decreases necrosis in skeletal muscle undergoing ischemia and reperfusion injury. ( Ascher, E; Cheng, W; Hanson, JN; Hingorani, A; Scheinman, M, 2001) |
| "Retinal ischemia increased vitreous concentrations of glutamate and glycine." | 7.70 | Memantine is neuroprotective in a rat model of pressure-induced retinal ischemia. ( Bach, M; Feuerstein, TJ; Knörle, R; Lagrèze, WA, 1998) |
| "The objective of this investigation was to test the effects of glycine, a cytoprotectant in normothermic in vitro models of renal ischemia, in a model of hypothermic renal preservation injury." | 7.68 | Protective effects of glycine during hypothermic renal ischemia-reperfusion injury. ( Anderson, CB; Grabau, GG; Mangino, MJ; Murphy, MK, 1991) |
| " In the present study, we examined the neuroprotective potency of the selective mGluR5 agonist, (R,S)-2-chloro-5-hydroxyphenylglycine (CHPG), in endothelin-1(ET-1)-induced focal ischemia in rats." | 3.74 | No improvement of functional and histological outcome after application of the metabotropic glutamate receptor 5 agonist CHPG in a model of endothelin-1-induced focal ischemia in rats. ( Henrich-Noack, P; Reymann, KG; Riek-Burchardt, M, 2007) |
| "Glycine reduces ischemia-reperfusion injury after experimental liver transplantation." | 3.73 | Glycine application and right heart function in a porcine heart transplantation model. ( Haverich, A; Klima, U; Schulze, B; Steinkamp, T; Warnecke, G, 2006) |
| "The role of glycine has not been investigated in lung ischemia-reperfusion injury after cold preservation." | 3.72 | Glycine ameliorates lung reperfusion injury after cold preservation in an ex vivo rat lung model. ( Fukuse, T; Hasegawa, S; Ikeyama, K; Mizutani, Y; Omasa, M; Toyokuni, S; Wada, H; Yoshida, H, 2003) |
| "Glycine (GLY) is a neutral amino acid that has been shown to be cytoprotective in the kidneys of dogs and rabbits undergoing ischemia-reperfusion injury." | 3.71 | Glycine preserves function and decreases necrosis in skeletal muscle undergoing ischemia and reperfusion injury. ( Ascher, E; Cheng, W; Hanson, JN; Hingorani, A; Scheinman, M, 2001) |
| "The authors' previous laboratory results have shown that rats treated for 3 days with intravenous GLP-2alpha, a synthetic protease-resistant form of glucagonlike peptide-2, showed increased mucosal mass and absorptive function when compared with saline-treated controls after intestinal ischemia/reperfusion (I/R)." | 3.71 | GLP-2alpha accelerates recovery of mucosal absorptive function after intestinal ischemia/reperfusion. ( Alavi, K; Prasad, R; Schwartz, MZ, 2001) |
| "Retinal ischemia increased vitreous concentrations of glutamate and glycine." | 3.70 | Memantine is neuroprotective in a rat model of pressure-induced retinal ischemia. ( Bach, M; Feuerstein, TJ; Knörle, R; Lagrèze, WA, 1998) |
| "The objective of this investigation was to test the effects of glycine, a cytoprotectant in normothermic in vitro models of renal ischemia, in a model of hypothermic renal preservation injury." | 3.68 | Protective effects of glycine during hypothermic renal ischemia-reperfusion injury. ( Anderson, CB; Grabau, GG; Mangino, MJ; Murphy, MK, 1991) |
| "Temporary interruption of the circulation to the canine gallbladder causes hemorrhagic necrosis of the mucosa and an abolition of active transport of glycine in vitro." | 3.66 | Morphological and functional recovery of the canine gallbladder mucosa following two hours' ischemia. ( Mirkovitch, V; Ozzello, L; Robinson, JW; Winistörfer, B, 1980) |
| "Retinal ischemia is a common condition that may lead into vision impairment and blindness." | 1.56 | Differential sensitivity of the On and Off visual responses to retinal ischemia. ( Bermudez, MA; Gonzalez, F, 2020) |
| "Sivelestat treatment did not improve survival but increased PP and IE lymphocyte numbers significantly and reduced the LP CD8(+) cell percentage and plasma IL-6 concentration compared with controls." | 1.36 | Neutrophil elastase inhibitor restores gut ischemia reperfusion-induced impairment of gut immunity with reduced plasma interleukin-6 concentrations in mice. ( Fukatsu, K; Maeshima, Y; Omata, J; Saitoh, D; Tanabe, K; Yasuhara, H, 2010) |
| "In vitro models of anoxia have revealed severe changes in neuronal functions after ischaemia but not after aglycaemia, although hypoglycaemia produced severe neuronal dysfunctions sometimes leading to coma." | 1.32 | Effect of ischaemia & aglycaemia on the synaptic transmission in neonatal rat spinal cord in vitro. ( Dasgupta, S; Deshpande, SB; Jha, A, 2003) |
| "Liver ischemia was induced in rats by occluding the portal vein for 30 minutes, and ONO-5046 or anticoagulants were injected intravenously 5 minutes before vascular clamping." | 1.30 | Neutrophil elastase inhibitor reduces neutrophil chemoattractant production after ischemia-reperfusion in rat liver. ( Akizuki, E; Goto, M; Ichiguchi, O; Matsumura, F; Miyanari, N; Mori, K; Ogawa, M; Yamada, S; Yamaguchi, Y, 1997) |
| "Liver ischemia was induced in rats by occluding the portal vein for 30 min." | 1.30 | Neutrophil elastase and oxygen radicals enhance monocyte chemoattractant protein- expression after ischemia/reperfusion in rat liver. ( Ishihara, K; Liang, J; Matsuda, T; Matsumura, F; Mori, K; Ogawa, M; Ohshiro, H; Okabe, K; Yamaguchi, Y, 1999) |
| " LY354740 and LY379268 were protective against transient global ischemia in gerbils when dosed intraperitoneally." | 1.30 | Neuroprotective actions of novel and potent ligands of group I and group II metabotropic glutamate receptors. ( Battaglia, G; Bond, A; Bruno, V; Clark, BP; Harris, JR; Kingston, AE; Lodge, D; Monn, JA; Nicoletti, F; O'Neill, MJ; Schoepp, DD, 1999) |
| "She had a history of migraine going back 10 years." | 1.29 | [Ergotamine-induced rectal stenosis in a patient with long-term migraine]. ( Ell, C; Hahn, EG; Machnig, T; May, A; Steininger, H; von Streitberg, U, 1993) |
| "Glycine treatment did not attenuate the decrease of renal function in the 45-minute and 60-minute models, with serum creatinine averaging 2." | 1.29 | Infusion of glycine does not attenuate in vivo ischemic acute renal failure in the rat. ( Burke, TJ; Schrier, RW; Shanley, PF; Wetzels, JF; Yu, L, 1993) |
| "The PD rats demonstrated more severe acute renal failure at 24 h after the ischemic insult." | 1.27 | Detrimental effect of hypophosphatemia on the severity and progression of ischemic acute renal failure. ( Burke, TJ; Harris, DC; Lumlertgul, D; Schrier, RW, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (21.69) | 18.7374 |
| 1990's | 29 (34.94) | 18.2507 |
| 2000's | 18 (21.69) | 29.6817 |
| 2010's | 13 (15.66) | 24.3611 |
| 2020's | 5 (6.02) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, M | 1 |
| Dong, R | 1 |
| Yuan, J | 1 |
| Da, J | 1 |
| Zha, Y | 1 |
| Long, Y | 1 |
| Xie, M | 1 |
| Leng, T | 1 |
| Maysami, S | 1 |
| Pearson, A | 1 |
| Simon, R | 1 |
| Xiong, ZG | 1 |
| Meller, R | 1 |
| Bermudez, MA | 1 |
| Gonzalez, F | 1 |
| Singh, A | 1 |
| Wilson, JW | 1 |
| Schofield, CJ | 1 |
| Chen, R | 1 |
| Ohashi, K | 1 |
| Ouchi, N | 1 |
| Murohara, T | 1 |
| Garcia-Dorado, D | 1 |
| Rodriguez-Sinovas, A | 1 |
| Barba, I | 1 |
| Valls-Lacalle, L | 1 |
| Ruiz-Meana, M | 1 |
| Zacho, HD | 3 |
| Henriksen, JH | 1 |
| Abrahamsen, J | 2 |
| Dongó, E | 1 |
| Benkő, Z | 1 |
| Csizmazia, Á | 1 |
| Marosi, G | 1 |
| Grottke, A | 1 |
| Jücker, M | 1 |
| Schumacher, U | 1 |
| Kiss, L | 1 |
| Kim, D | 1 |
| Fiske, BP | 1 |
| Birsoy, K | 1 |
| Freinkman, E | 1 |
| Kami, K | 1 |
| Possemato, RL | 1 |
| Chudnovsky, Y | 1 |
| Pacold, ME | 1 |
| Chen, WW | 1 |
| Cantor, JR | 1 |
| Shelton, LM | 1 |
| Gui, DY | 1 |
| Kwon, M | 1 |
| Ramkissoon, SH | 1 |
| Ligon, KL | 1 |
| Kang, SW | 1 |
| Snuderl, M | 1 |
| Vander Heiden, MG | 1 |
| Sabatini, DM | 1 |
| Hanuska, A | 1 |
| Szénási, G | 2 |
| Albert, M | 2 |
| Koles, L | 1 |
| Varga, A | 1 |
| Szabo, A | 1 |
| Matyus, P | 2 |
| Harsing, LG | 2 |
| Hanff, E | 1 |
| Kayacelebi, AA | 1 |
| Yanchev, GR | 1 |
| Maassen, N | 1 |
| Haghikia, A | 1 |
| Tsikas, D | 1 |
| Schellinger, IN | 1 |
| Cordasic, N | 1 |
| Panesar, J | 1 |
| Buchholz, B | 1 |
| Jacobi, J | 1 |
| Hartner, A | 1 |
| Klanke, B | 1 |
| Jakubiczka-Smorag, J | 1 |
| Burzlaff, N | 1 |
| Heinze, E | 1 |
| Warnecke, C | 1 |
| Raaz, U | 1 |
| Willam, C | 1 |
| Tsao, PS | 1 |
| Eckardt, KU | 1 |
| Amann, K | 1 |
| Hilgers, KF | 1 |
| Zhou, JL | 1 |
| Huang, YS | 1 |
| Song, HP | 1 |
| Dang, YM | 1 |
| Zhang, DX | 1 |
| Zhang, Q | 1 |
| Qiu, W | 1 |
| Wei, R | 1 |
| Zhang, C | 2 |
| Leng, W | 1 |
| Wang, W | 1 |
| Fukatsu, K | 1 |
| Tanabe, K | 1 |
| Maeshima, Y | 1 |
| Omata, J | 1 |
| Yasuhara, H | 1 |
| Saitoh, D | 1 |
| de Souza, CF | 1 |
| Acosta, ML | 1 |
| Polkinghorne, PJ | 1 |
| McGhee, CN | 1 |
| Kalloniatis, M | 2 |
| Matsumoto, N | 1 |
| Kumamoto, E | 1 |
| Furue, H | 1 |
| Yoshimura, M | 1 |
| Kim, JS | 1 |
| Qian, T | 1 |
| Lemasters, JJ | 1 |
| Omasa, M | 1 |
| Fukuse, T | 1 |
| Toyokuni, S | 1 |
| Mizutani, Y | 1 |
| Yoshida, H | 1 |
| Ikeyama, K | 1 |
| Hasegawa, S | 1 |
| Wada, H | 1 |
| Bui, BV | 1 |
| Vingrys, AJ | 1 |
| Jha, A | 1 |
| Dasgupta, S | 1 |
| Deshpande, SB | 1 |
| Kan, HE | 1 |
| Renema, WK | 1 |
| Isbrandt, D | 1 |
| Heerschap, A | 1 |
| Dijk, F | 2 |
| van Leeuwen, S | 1 |
| Kamphuis, W | 2 |
| Kotake, Y | 1 |
| Yamamoto, M | 1 |
| Matsumoto, M | 1 |
| Morisaki, H | 1 |
| Takeda, J | 1 |
| Warnecke, G | 1 |
| Schulze, B | 1 |
| Steinkamp, T | 1 |
| Haverich, A | 1 |
| Klima, U | 1 |
| Riek-Burchardt, M | 1 |
| Henrich-Noack, P | 1 |
| Reymann, KG | 1 |
| Katsuki, H | 1 |
| Watanabe, Y | 1 |
| Fujimoto, S | 1 |
| Kume, T | 1 |
| Akaike, A | 1 |
| Moussavian, MR | 1 |
| Slotta, JE | 1 |
| Kollmar, O | 1 |
| Menger, MD | 1 |
| Gronow, G | 1 |
| Schilling, MK | 1 |
| Winistörfer, B | 2 |
| Mirkovitch, V | 6 |
| Robinson, JW | 6 |
| Ozzello, L | 1 |
| Sikujara, O | 1 |
| Monden, M | 1 |
| Toyoshima, K | 1 |
| Okamura, J | 1 |
| Kosaki, G | 1 |
| Threlfall, CJ | 1 |
| Maxwell, AR | 1 |
| Stoner, HB | 1 |
| Rokkas, CK | 2 |
| Cronin, CS | 1 |
| Nitta, T | 1 |
| Helfrich, LR | 2 |
| Lobner, DC | 2 |
| Choi, DW | 2 |
| Kouchoukos, NT | 2 |
| Ozaki, M | 1 |
| Ozasa, H | 1 |
| Fuchinoue, S | 1 |
| Teraoka, S | 1 |
| Ota, K | 1 |
| Brockbank, KG | 1 |
| Dawson, PE | 1 |
| Machnig, T | 1 |
| May, A | 1 |
| Steininger, H | 1 |
| von Streitberg, U | 1 |
| Hahn, EG | 1 |
| Ell, C | 1 |
| Marsh, DC | 2 |
| Vreugdenhil, PK | 2 |
| Mack, VE | 1 |
| Belzer, FO | 2 |
| Southard, JH | 2 |
| Wetzels, JF | 1 |
| Yu, L | 1 |
| Shanley, PF | 1 |
| Burke, TJ | 2 |
| Schrier, RW | 2 |
| Ferguson, DM | 1 |
| Gores, GJ | 1 |
| Bronk, SF | 1 |
| Krom, RA | 1 |
| Tomizawa, N | 3 |
| Ohwada, S | 3 |
| Ohya, T | 3 |
| Takahashi, T | 2 |
| Ichikawa, H | 2 |
| Kobayashi, J | 2 |
| Kamoshita, N | 2 |
| Iino, Y | 2 |
| Morishita, Y | 3 |
| Ogawa, T | 1 |
| Izumi, M | 1 |
| Nakamura, S | 1 |
| Mangino, JE | 1 |
| Kotadia, B | 1 |
| Mangino, MJ | 2 |
| Ikejima, K | 1 |
| Iimuro, Y | 1 |
| Forman, DT | 1 |
| Thurman, RG | 1 |
| Sakaida, I | 1 |
| Nagatomi, A | 1 |
| Okita, K | 1 |
| Yamaguchi, Y | 2 |
| Akizuki, E | 1 |
| Ichiguchi, O | 1 |
| Matsumura, F | 2 |
| Goto, M | 1 |
| Miyanari, N | 1 |
| Mori, K | 2 |
| Yamada, S | 1 |
| Ogawa, M | 2 |
| Muller, A | 1 |
| Villain, M | 1 |
| Bonne, C | 1 |
| Chavez-Cartaya, R | 1 |
| Ramirez, P | 1 |
| Fuente, T | 1 |
| DeSola, GP | 1 |
| Marin, J | 1 |
| Piñero, A | 1 |
| Parrilla, P | 1 |
| Jamieson, NV | 1 |
| Lagrèze, WA | 1 |
| Knörle, R | 1 |
| Bach, M | 1 |
| Feuerstein, TJ | 1 |
| Kawashima, Y | 1 |
| Takeyoshi, I | 1 |
| Buchman, AL | 1 |
| O'Brien, W | 1 |
| Ou, CN | 1 |
| Rognerud, C | 1 |
| Alvarez, M | 1 |
| Dennis, K | 1 |
| Ahn, C | 1 |
| Soejima, Y | 1 |
| Yanaga, K | 1 |
| Nishizaki, T | 1 |
| Yoshizumi, T | 1 |
| Uchiyama, H | 1 |
| Sugimachi, K | 1 |
| Chen, HM | 1 |
| Chen, JC | 1 |
| Shyr, MH | 1 |
| Chen, MF | 1 |
| Hwang, TL | 1 |
| Fan, LL | 1 |
| Chi, TY | 1 |
| Chi, CP | 1 |
| Liang, J | 1 |
| Okabe, K | 1 |
| Ohshiro, H | 1 |
| Ishihara, K | 1 |
| Matsuda, T | 1 |
| Kingston, AE | 1 |
| O'Neill, MJ | 1 |
| Bond, A | 1 |
| Bruno, V | 1 |
| Battaglia, G | 1 |
| Nicoletti, F | 1 |
| Harris, JR | 1 |
| Clark, BP | 1 |
| Monn, JA | 1 |
| Lodge, D | 1 |
| Schoepp, DD | 1 |
| Ascher, E | 1 |
| Hanson, JN | 1 |
| Cheng, W | 1 |
| Hingorani, A | 1 |
| Scheinman, M | 1 |
| Prasad, R | 1 |
| Alavi, K | 1 |
| Schwartz, MZ | 1 |
| Lee, MA | 1 |
| McCauley, RD | 1 |
| Kong, SE | 1 |
| Hall, JC | 1 |
| Kato, S | 1 |
| Umeda, M | 1 |
| Takeeda, M | 1 |
| Kanatsu, K | 1 |
| Takeuchi, K | 1 |
| Gomba, S | 2 |
| Fischer, A | 2 |
| Vouron, J | 1 |
| Meldrum, BS | 1 |
| Papy, JJ | 1 |
| Toure, MF | 1 |
| Brierley, JB | 1 |
| Hood, WF | 1 |
| Gray, NM | 1 |
| Dappen, MS | 1 |
| Watson, GB | 1 |
| Compton, RP | 1 |
| Cordi, AA | 1 |
| Lanthorn, TH | 1 |
| Monahan, JB | 1 |
| Paller, MS | 1 |
| Patten, M | 1 |
| Murphy, MK | 1 |
| Grabau, GG | 1 |
| Anderson, CB | 1 |
| Simpson, RK | 1 |
| Robertson, CS | 1 |
| Goodman, JC | 1 |
| Hjelmhaug, JA | 1 |
| Weinberg, JM | 1 |
| Martiniak, J | 2 |
| Chavko, M | 2 |
| Danielisová, V | 1 |
| Marsala, J | 2 |
| Lumlertgul, D | 1 |
| Harris, DC | 1 |
| Borgeaud, J | 3 |
| Campiche, M | 1 |
| Discombe, G | 1 |
| Lund, S | 1 |
| Zimmer, HG | 3 |
| Trendelenburg, C | 2 |
| Kammermeier, H | 1 |
| Gerlach, E | 3 |
| Kontos, HA | 1 |
| Thames, MD | 1 |
| Lombana, A | 1 |
| Watlington, CO | 1 |
| Jessee, F | 1 |
| Marko, P | 2 |
| Pechan, I | 1 |
| Gourley, DR | 1 |
| Schwarzmeier, J | 1 |
| Stern, P | 1 |
| Hadzović, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Controlled and Randomized Clinical Trial for Evaluating the Effect of a Supplement of Glycine as Adjuvant in the Treatment of COVID-19 Pneumonia in Patients Initiating Mechanical Ventilation[NCT04443673] | 59 participants (Actual) | Interventional | 2020-06-15 | Terminated (stopped due to An interim analysis showed no difference in major outcomes (n=35 glycine and n=24 control participants)) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for glycine and Ischemia
| Article | Year |
|---|---|
Chronic intestinal ischaemia: measurement of the total splanchnic blood flow.
Topics: Angiography; Aniline Compounds; Animals; Anthropometry; Chronic Disease; Fasting; Glycine; Humans; I | 2013 |
The effect of amino acids on ischemic and toxic injury to the kidney.
Topics: Acute Kidney Injury; Alanine; Amino Acids; Animals; Glutathione; Glycine; Humans; Ischemia; Kidney | 1990 |
2 trials available for glycine and Ischemia
| Article | Year |
|---|---|
Functional versus radiological assessment of chronic intestinal ischaemia.
Topics: Adult; Aged; Aged, 80 and over; Angiography; Aniline Compounds; Blood Flow Velocity; Chronic Disease | 2010 |
The effect of arginine or glycine supplementation on gastrointestinal function, muscle injury, serum amino acid concentrations and performance during a marathon run.
Topics: Adult; Amino Acids; Arginine; Dietary Supplements; Female; Gastrointestinal Hemorrhage; Glycine; Hum | 1999 |
79 other studies available for glycine and Ischemia
| Article | Year |
|---|---|
Roxadustat (FG-4592) protects against ischaemia/reperfusion-induced acute kidney injury through inhibiting the mitochondrial damage pathway in mice.
Topics: Acute Kidney Injury; Animals; Apoptosis; Glycine; Ischemia; Isoquinolines; Kidney; Mice; Mice, Inbre | 2022 |
Changes in NMDA Receptor Function in Rapid Ischemic Tolerance: A Potential Role for Tri-Heteromeric NMDA Receptors.
Topics: Actins; Animals; Glycine; Ischemia; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate | 2022 |
Differential sensitivity of the On and Off visual responses to retinal ischemia.
Topics: Animals; Disease Models, Animal; Electroretinography; Female; Glycine; Intravitreal Injections; Isch | 2020 |
Hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitors induce autophagy and have a protective effect in an in-vitro ischaemia model.
Topics: Amino Acids, Dicarboxylic; Animals; Autophagy; Barbiturates; Flow Cytometry; Fluorescent Antibody Te | 2020 |
Can Pharmacological Ischemic Preconditioning Affect Myocardial Ischemic Injury?
Topics: Animals; Glycine; Ischemia; Ischemic Preconditioning, Myocardial; Isoquinolines; Mice; Myocardial Re | 2020 |
Reply: Glycine as a key element of remote ischaemic conditioning cardioprotective signalling.
Topics: Glycine; Humans; Ischemia; Ischemic Preconditioning, Myocardial; Myocardial Reperfusion Injury; Rece | 2017 |
Chronic intestinal ischemia and splanchnic blood-flow: reference values and correlation with body-composition.
Topics: Absorptiometry, Photon; Adult; Aged; Aged, 80 and over; Aniline Compounds; Body Composition; Body We | 2013 |
H2S preconditioning of human adipose tissue-derived stem cells increases their efficacy in an in vitro model of cell therapy for simulated ischemia.
Topics: Adipose Tissue; Adult; Alkynes; Animals; Antioxidants; Cell Line; Cell Proliferation; Cell Survival; | 2014 |
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.
Topics: Acetone; Animals; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Female; Glioblasto | 2015 |
Some Operational Characteristics of Glycine Release in Rat Retina: The Role of Reverse Mode Operation of Glycine Transporter Type-1 (GlyT-1) in Ischemic Conditions.
Topics: Animals; Calcium; Glucose; Glycine; Glycine Plasma Membrane Transport Proteins; Ischemia; Male; Ouab | 2016 |
Simultaneous stable-isotope dilution GC-MS measurement of homoarginine, guanidinoacetate and their common precursor arginine in plasma and their interrelationships in healthy and diseased humans.
Topics: Adult; Aged; Arginine; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Glycine; Healthy Vol | 2016 |
Hypoxia inducible factor stabilization improves defective ischemia-induced angiogenesis in a rodent model of chronic kidney disease.
Topics: Animals; Capillaries; Carbon Monoxide; Cell Line; Disease Models, Animal; Gene Expression Regulation | 2017 |
[Effects of glycine on apoptosis in murine cardiomyocyte suffering from ischemia and hypoxia].
Topics: Animals; Apoptosis; Caspase 3; Cell Hypoxia; Cells, Cultured; Glycine; Ischemia; Myocytes, Cardiac; | 2008 |
A glycine site-specific NMDA receptor antagonist protects retina ganglion cells from ischemic injury by modulating apoptotic cascades.
Topics: Animals; Apoptosis; Cytoprotection; Eye Proteins; Frozen Sections; Gene Expression Regulation; Glyci | 2010 |
Neutrophil elastase inhibitor restores gut ischemia reperfusion-induced impairment of gut immunity with reduced plasma interleukin-6 concentrations in mice.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Flow Cytometry; Gastrointestinal Tract; Glycine; | 2010 |
Inhibition of hypoxia-induced [(3)H]glycine release from chicken retina by the glycine transporter type-1 (GlyT-1) inhibitors NFPS and Org-24461.
Topics: Animals; Chickens; Electric Stimulation; Fluorescent Antibody Technique, Indirect; Glycine; Glycine | 2012 |
Amino acid immunoreactivity in normal human retina and after brachytherapy.
Topics: Aged; Amino Acids; Brachytherapy; Eye Banks; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glyc | 2013 |
GABA-mediated inhibition of glutamate release during ischemia in substantia gelatinosa of the adult rat.
Topics: Age Factors; Anesthetics, Local; Animals; Bicuculline; Excitatory Postsynaptic Potentials; GABA Anta | 2003 |
Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes.
Topics: Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Cyclosporine; Energy M | 2003 |
Glycine ameliorates lung reperfusion injury after cold preservation in an ex vivo rat lung model.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Blood Pressure; Cryopreservation; Cytoprotection; D | 2003 |
Correlating retinal function and amino acid immunocytochemistry following post-mortem ischemia.
Topics: Animals; Aspartic Acid; Electroretinography; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Immuno | 2003 |
Effect of ischaemia & aglycaemia on the synaptic transmission in neonatal rat spinal cord in vitro.
Topics: Animals; Animals, Newborn; Cell Hypoxia; Glucose; Glycine; Hypoxia; Ischemia; Magnesium; N-Methylasp | 2003 |
Phosphorylated guanidinoacetate partly compensates for the lack of phosphocreatine in skeletal muscle of mice lacking guanidinoacetate methyltransferase.
Topics: Adenosine Triphosphate; Animals; Creatine; Glycine; Guanidinoacetate N-Methyltransferase; Homeostasi | 2004 |
Differential effects of ischemia/reperfusion on amacrine cell subtype-specific transcript levels in the rat retina.
Topics: Amacrine Cells; Animals; Cluster Analysis; gamma-Aminobutyric Acid; Gene Expression Regulation; Glia | 2004 |
An immunocytochemical study on specific amacrine cell subpopulations in the rat retina after ischemia.
Topics: Amacrine Cells; Animals; Cell Count; Eye Diseases; gamma-Aminobutyric Acid; Gene Expression Regulati | 2004 |
Sivelestat, a neutrophil elastase inhibitor, attenuates neutrophil priming after hepatoenteric ischemia in rabbits.
Topics: Acetylglucosaminidase; Animals; Bronchoalveolar Lavage Fluid; Glycine; Ischemia; L-Lactate Dehydroge | 2005 |
Glycine application and right heart function in a porcine heart transplantation model.
Topics: Animals; Creatine Kinase, MB Form; Diastole; Glycine; Heart; Heart Transplantation; Ischemia; Liver | 2006 |
No improvement of functional and histological outcome after application of the metabotropic glutamate receptor 5 agonist CHPG in a model of endothelin-1-induced focal ischemia in rats.
Topics: Animals; Behavior, Animal; Brain Infarction; Disease Models, Animal; Endothelin-1; Excitatory Amino | 2007 |
Contribution of endogenous glycine and d-serine to excitotoxic and ischemic cell death in rat cerebrocortical slice cultures.
Topics: Animals; Animals, Newborn; Cell Death; Cell Survival; Cerebral Cortex; Excitatory Amino Acid Agonist | 2007 |
Post-hypoxic cellular disintegration in glycine-preserved renal tubules is attenuated by hydroxyl radical scavengers and iron chelators.
Topics: Animals; Cell Death; Cell Hypoxia; Cytoplasm; Enzymes; Female; Free Radical Scavengers; Gluconeogene | 2008 |
Morphological and functional recovery of the canine gallbladder mucosa following two hours' ischemia.
Topics: Animals; Biological Transport, Active; Dogs; Female; Gallbladder; Glycine; Ischemia; Male; Mucous Me | 1980 |
Cytoprotective effect of prostaglandin I2 on ischemia-induced hepatic cell injury.
Topics: Adenosine Triphosphate; Animals; Cyclic AMP; Cyclic GMP; Epoprostenol; Glycine; Ischemia; Liver; Mal | 1983 |
Post-traumatic creatinuria.
Topics: Adult; Animals; Creatine; Creatinine; DNA; Female; Fractures, Bone; Glycine; Hindlimb; Humans; Ische | 1984 |
Profound systemic hypothermia inhibits the release of neurotransmitter amino acids in spinal cord ischemia.
Topics: Analysis of Variance; Animals; Aspartic Acid; Cardiopulmonary Bypass; Disease Models, Animal; Evoked | 1995 |
Dextrorphan inhibits the release of excitatory amino acids during spinal cord ischemia.
Topics: Amino Acids; Animals; Aspartic Acid; Dextrorphan; Evoked Potentials; Evoked Potentials, Somatosensor | 1994 |
Protective effects of glycine and esterified gamma-glutamylcysteine on ischemia/reoxygenation injury of rat liver.
Topics: Animals; Dipeptides; Glutathione; Glycine; Ischemia; Liver; Male; Rats; Rats, Wistar; Reperfusion In | 1994 |
Influence of whole heart postprocurement cold ischemia time upon cryopreserved heart valve viability.
Topics: Cold Temperature; Cryopreservation; Deoxyglucose; Glycine; Heart; Heart Valves; Humans; Hypoxanthine | 1993 |
[Ergotamine-induced rectal stenosis in a patient with long-term migraine].
Topics: Adult; Aminopyrine; Biopsy; Caffeine; Colonoscopy; Dilatation; Drug Combinations; Ergotamine; Female | 1993 |
Glycine protects hepatocytes from injury caused by anoxia, cold ischemia and mitochondrial inhibitors, but not injury caused by calcium ionophores or oxidative stress.
Topics: Amino Acids; Animals; Calcimycin; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cold Temperature; Glyci | 1993 |
Infusion of glycine does not attenuate in vivo ischemic acute renal failure in the rat.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Diuresis; Glycine; Ischemia; Kidney; | 1993 |
An increase in cytosolic protease activity during liver preservation. Inhibition by glutathione and glycine.
Topics: Animals; Aspartic Acid Endopeptidases; Cytosol; Endopeptidases; Glutathione; Glycine; Glycoside Hydr | 1993 |
Effects of neutrophil elastase inhibitor on reperfusion injury in the canine liver.
Topics: Alanine Transaminase; Animals; Biomarkers; Dogs; Glycine; Hyaluronic Acid; Ischemia; L-Lactate Dehyd | 1996 |
Effects of a specific neutrophil elastase inhibitor (ONO-5046 Na) and neutrophil depletion using a G-1 column on lung reperfusion injury in dogs.
Topics: Animals; Chromatography; Dogs; Glycine; Graft Survival; Ischemia; Leukapheresis; Leukocyte Count; Le | 1996 |
Characterization of hypothermic intestinal ischemia-reperfusion injury in dogs. Effects of glycine.
Topics: Animals; Dogs; Glycine; Hypertonic Solutions; Hypothermia, Induced; Intestinal Mucosa; Intestine, Sm | 1996 |
A diet containing glycine improves survival in endotoxin shock in the rat.
Topics: Animal Feed; Animals; Calcium; Cells, Cultured; Disease Models, Animal; Glycine; Ischemia; Kupffer C | 1996 |
Protection by glycine against chemical ischemia produced by cyanide in cultured hepatocytes.
Topics: Analysis of Variance; Animals; Cell Survival; Cells, Cultured; Cyanides; Drug Interactions; Glycine; | 1996 |
Neutrophil elastase inhibitor reduces neutrophil chemoattractant production after ischemia-reperfusion in rat liver.
Topics: Animals; Antithrombin III; Aspartate Aminotransferases; Chemokines, CXC; Chemotactic Factors; Drug S | 1997 |
The release of amino acids from ischemic retina.
Topics: Alanine; Amino Acids; Animals; Glutamic Acid; Glycine; Ischemia; Male; Ocular Hypertension; Rabbits; | 1997 |
Blood clearance of 99mTc-trimethyl-Br-IDA discriminates between different degrees of severe liver ischaemia--reperfusion injury in the rat.
Topics: Alanine Transaminase; Aniline Compounds; Animals; Galactosemias; Glycine; Imino Acids; Ischemia; Liv | 1997 |
Memantine is neuroprotective in a rat model of pressure-induced retinal ischemia.
Topics: Animals; Cell Count; Chromatography, High Pressure Liquid; Disease Models, Animal; Excitatory Amino | 1998 |
The effect of neutrophil elastase inhibitor in hepatectomy with ischemia in dogs.
Topics: Alanine Transaminase; Animals; Biomarkers; Dogs; Endothelium, Vascular; Glycine; Hemorrhage; Hepatec | 1999 |
Effect of specific neutrophil elastase inhibitor on ischemia/reperfusion injury in rat liver transplantation.
Topics: Adenine Nucleotides; Animals; Bile; Glycine; Hyaluronic Acid; Ischemia; Leukocyte Elastase; Liver; L | 1999 |
Neutrophil elastase inhibitor (ONO-5046) attenuates reperfusion-induced hepatic microcirculatory derangement, energy depletion and lipid peroxidation in rats.
Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Glycine; Hemodynamics; Ischemia; Laser-Doppler F | 1999 |
Neutrophil elastase and oxygen radicals enhance monocyte chemoattractant protein- expression after ischemia/reperfusion in rat liver.
Topics: Animals; Antithrombin III; Cell Hypoxia; Cells, Cultured; Chemokine CCL2; Enzyme-Linked Immunosorben | 1999 |
Neuroprotective actions of novel and potent ligands of group I and group II metabotropic glutamate receptors.
Topics: Animals; Benzoates; Bridged Bicyclo Compounds; Cells, Cultured; Cerebral Cortex; Drug Evaluation, Pr | 1999 |
Glycine preserves function and decreases necrosis in skeletal muscle undergoing ischemia and reperfusion injury.
Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Dogs; Glycine; Infusions, Intra-Arterial; I | 2001 |
GLP-2alpha accelerates recovery of mucosal absorptive function after intestinal ischemia/reperfusion.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Galactose; Glucagon-Like Peptides; Glycine; I | 2001 |
Pretreatment with glycine reduces the severity of warm intestinal ischemic-reperfusion injury in the rat.
Topics: Animals; Chi-Square Distribution; Glycine; Infusions, Intra-Arterial; Ischemia; Jejunum; Male; Rats; | 2001 |
Effect of taurine on ulcerogenic response and impaired ulcer healing induced by monochloramine in rat stomachs.
Topics: Administration, Oral; Animals; Chloramines; Dose-Response Relationship, Drug; Gastric Mucosa; Glycin | 2002 |
Influence of short-term hypothermia upon the normal or ischaemic dog kidney.
Topics: Acid Phosphatase; Adenosine Triphosphatases; Animals; Dogs; Female; Glomerular Filtration Rate; Glyc | 1976 |
Alterations in the dog renal tubular epithelium during normothermic ischemia.
Topics: Acid Phosphatase; Animals; Dogs; Epithelium; Glycine; Ischemia; Kidney; Kidney Tubules; Lysosomes; O | 1977 |
Four models for studying cerebral lesions secondary to epileptic seizures.
Topics: Animals; Astrocytes; Bicuculline; Blood Gas Analysis; Blood Glucose; Blood Pressure; Body Temperatur | 1975 |
Characterization of indole-2-carboxylate derivatives as antagonists of N-methyl-D-aspartate receptor activity at the associated glycine recognition site.
Topics: Animals; Binding Sites; Carboxylic Acids; Dizocilpine Maleate; Gerbillinae; Glycine; Indoles; Ischem | 1992 |
Protective effects of glutathione, glycine, or alanine in an in vitro model of renal anoxia.
Topics: Alanine; Animals; Buthionine Sulfoximine; Cells, Cultured; Glutathione; Glycine; Hypoxia; Ischemia; | 1992 |
Protective effects of glycine during hypothermic renal ischemia-reperfusion injury.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Adenine Nucleotides; Animals; Dogs; Glutathione; Glycine; Hypoth | 1991 |
Spinal cord ischemia-induced elevation of amino acids: extracellular measurement with microdialysis.
Topics: Amino Acids; Animals; Asparagine; Chromatography, High Pressure Liquid; Dialysis; Extracellular Spac | 1990 |
Glycine prevention of cold ischemic injury in isolated hepatocytes.
Topics: Animals; Cell Survival; Cold Temperature; Cryoprotective Agents; Glutathione; Glycine; In Vitro Tech | 1991 |
Regional concentrations of transmitter amino acids after spinal cord ischaemia in the rabbit.
Topics: Amino Acids; Animals; Aspartic Acid; Female; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine | 1989 |
Free amino acids in the spinal cord and ganglia of dogs after ligation of the abdominal aorta.
Topics: Alanine; Amino Acids; Animals; Aorta, Abdominal; Aspartic Acid; Dogs; Female; Ganglia, Spinal; Gluta | 1985 |
Detrimental effect of hypophosphatemia on the severity and progression of ischemic acute renal failure.
Topics: Acute Kidney Injury; Administration, Oral; Aluminum Hydroxide; Animals; Body Weight; Diet; Glycine; | 1986 |
The response of the dog kidney to transplant rejection or ischaemia: an experimental and comparative study with functional, microcirculatory and enzymological investigations.
Topics: Adenosine Triphosphatases; Animals; Biological Transport, Active; Dogs; Female; Glomerular Filtratio | 1972 |
[Active transport within the renal cortex following ischemia and hypothermic conservation].
Topics: Acid Phosphatase; Adenosine Triphosphatases; Animals; Biological Transport, Active; Creatinine; Dogs | 1973 |
ATPase behaviour and cortical transport in dog kidney after ischaemia.
Topics: Adenosine Triphosphatases; Animals; Biological Transport; Dogs; Glycine; In Vitro Techniques; Ischem | 1973 |
Urea inhibition of lactate dehydrogenase. A convenient routine procedure.
Topics: Anemia; Buffers; Clinical Enzyme Tests; Glycine; Humans; Ischemia; L-Lactate Dehydrogenase; Liver; L | 1970 |
De novo synthesis of myocardial adenine nucleotides in the rat. Acceleration during recovery from oxygen deficiency.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals | 1973 |
Vasodilator effects of local hypercapnic acidosis in dog skeletal muscle.
Topics: Acidosis; Animals; Calcium; Carbon Dioxide; Dilatation; Dogs; Glycine; Hydrochloric Acid; Hydrogen-I | 1971 |
Different response of adenine nucleotide synthesis de novo in kidney and brain during aerobic recovery from anoxia and ischemia.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aerobio | 1971 |
[In vivo studies on post-ischemic nucleotide, RNA and protein synthesis in kidney and brain].
Topics: Adenine; Animals; Brain; Carbon Isotopes; Cerebrovascular Circulation; Glycine; Ischemia; Kidney; Ne | 1969 |
Effect of glycine on experimental hind-limb rigidity in rats.
Topics: Animals; Aorta; Female; Glycine; Hindlimb; Interneurons; Ischemia; Male; Methods; Rats; Spasm; Spina | 1970 |