glycine has been researched along with Injuries, Spinal Cord in 43 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glycine is an inhibitory neurotransmitter that functions postsynaptically and also modulates the N-methyl-D-aspartate receptor." | 2.40 | Neurotransmission by neurons that use serotonin, noradrenaline, glutamate, glycine, and gamma-aminobutyric acid in the normal and injured spinal cord. ( Shapiro, S, 1997) |
| "Rats with complete spinal cord transection (SCT) can recover hindlimb locomotor function under strategies combining exercise training and 5-HT agonist treatment." | 1.48 | Changes in innervation of lumbar motoneurons and organization of premotor network following training of transected adult rats. ( Bras, H; Brezun, JM; Coq, JO; Coulon, P; Khalki, L; Lerond, J; Sadlaoud, K; Vinay, L, 2018) |
| "After spinal cord transection, the generation of stepping depends on neurotransmitter systems entirely contained within the local lumbar spinal cord." | 1.37 | Adaptations in glutamate and glycine content within the lumbar spinal cord are associated with the generation of novel gait patterns in rats following neonatal spinal cord transection. ( Cantoria, MJ; de Leon, RD; See, PA; Singh, H, 2011) |
| "Management of neuropathic pain remains problematic; however, cell therapy to treat the effects of pain on the sensory system after spinal cord injury (SCI) could be a useful approach." | 1.35 | Clinical feasibility for cell therapy using human neuronal cell line to treat neuropathic behavioral hypersensitivity following spinal cord injury in rats. ( Eaton, MJ; Wolfe, SQ, 2009) |
| "Spinal cord injury-induced spasticity, in the tail musculature, does not appear to involve either an increase in monosynaptic glutamatergic inputs from myelinated afferents or a decrease in glycinergic inputs to sacrocaudal motoneurons." | 1.34 | VGLUT1 and GLYT2 labeling of sacrocaudal motoneurons in the spinal cord injured spastic rat. ( Kitzman, P, 2007) |
| "Sixteen patients undergoing thoracoabdominal aortic aneurysm operations had cerebrospinal fluid drawn through lumbar spinal drains preoperatively, intraoperatively, and postoperatively." | 1.30 | Clinical markers in CSF for determining neurologic deficits after thoracoabdominal aortic aneurysm repairs. ( Baumgartner, WA; Brock, MV; Ishiwa, S; Johnston, MV; Laschinger, JC; Redmond, JM; Williams, GM, 1997) |
| "Surgical spinal cord transection to remove all ascending connections originating caudal to the transection (in tadpoles immobilized in alpha-bungarotoxin) did not affect "fictive" swimming generated more rostrally." | 1.30 | Roles of ascending inhibition during two rhythmic motor patterns in Xenopus tadpoles. ( Green, CS; Soffe, SR, 1998) |
| "The role of glycine in spasticity and spinal shock was explored further in rabbits with ischemic spinal cord injuries that produced spastic paraparesis or flaccid paraplegia." | 1.29 | The role of glycine in spinal shock. ( Goodman, JC; Robertson, CS; Simpson, RK, 1996) |
| "To determine whether spinal cord trauma alters the concentrations of extracellular amino acids, microdialysis was conducted in spinal cord during and after administration of impact trauma." | 1.28 | Alteration in extracellular amino acids after traumatic spinal cord injury. ( Faden, AI; Panter, SS; Yum, SW, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.65) | 18.7374 |
| 1990's | 9 (20.93) | 18.2507 |
| 2000's | 18 (41.86) | 29.6817 |
| 2010's | 13 (30.23) | 24.3611 |
| 2020's | 1 (2.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bras, H | 5 |
| Liabeuf, S | 4 |
| Kopach, O | 1 |
| Medvediev, V | 1 |
| Krotov, V | 1 |
| Borisyuk, A | 1 |
| Tsymbaliuk, V | 1 |
| Voitenko, N | 1 |
| Khalki, L | 1 |
| Sadlaoud, K | 3 |
| Lerond, J | 1 |
| Coq, JO | 1 |
| Brezun, JM | 1 |
| Vinay, L | 5 |
| Coulon, P | 2 |
| Kumar, H | 1 |
| Choi, H | 1 |
| Jo, MJ | 1 |
| Joshi, HP | 1 |
| Muttigi, M | 1 |
| Bonanomi, D | 1 |
| Kim, SB | 1 |
| Ban, E | 1 |
| Kim, A | 1 |
| Lee, SH | 1 |
| Kim, KT | 1 |
| Sohn, S | 1 |
| Zeng, X | 1 |
| Han, I | 1 |
| Ziemlińska, E | 1 |
| Kügler, S | 1 |
| Schachner, M | 2 |
| Wewiór, I | 1 |
| Czarkowska-Bauch, J | 1 |
| Skup, M | 1 |
| Fernández-López, B | 1 |
| Valle-Maroto, SM | 1 |
| Barreiro-Iglesias, A | 1 |
| Rodicio, MC | 1 |
| Sabin, K | 1 |
| Santos-Ferreira, T | 1 |
| Essig, J | 1 |
| Rudasill, S | 1 |
| Echeverri, K | 1 |
| Wu, K | 1 |
| Zhou, K | 1 |
| Wang, Y | 1 |
| Zhou, Y | 1 |
| Tian, N | 1 |
| Wu, Y | 1 |
| Chen, D | 1 |
| Zhang, D | 1 |
| Wang, X | 1 |
| Xu, H | 1 |
| Zhang, X | 1 |
| Huo, J | 1 |
| Zhu, XL | 1 |
| Ma, R | 1 |
| Dong, HL | 1 |
| Su, BX | 1 |
| Gonzalez-Piña, R | 1 |
| Nuño-Licona, A | 1 |
| Lee, HJ | 1 |
| Jakovcevski, I | 1 |
| Radonjic, N | 1 |
| Hoelters, L | 1 |
| Irintchev, A | 1 |
| Iwamoto, S | 1 |
| Higashi, A | 1 |
| Ueno, T | 1 |
| Goto, M | 1 |
| Iguro, Y | 1 |
| Sakata, R | 1 |
| Eaton, MJ | 2 |
| Wolfe, SQ | 2 |
| Byrnes, KR | 1 |
| Stoica, B | 1 |
| Riccio, A | 1 |
| Pajoohesh-Ganji, A | 1 |
| Loane, DJ | 1 |
| Faden, AI | 3 |
| Boulenguez, P | 3 |
| Bos, R | 2 |
| Jean-Xavier, C | 2 |
| Brocard, C | 3 |
| Stil, A | 2 |
| Darbon, P | 1 |
| Cattaert, D | 1 |
| Delpire, E | 1 |
| Marsala, M | 1 |
| Tazerart, S | 2 |
| Portalier, P | 1 |
| Brocard, F | 2 |
| Viemari, JC | 1 |
| Pearlstein, E | 1 |
| Cantoria, MJ | 1 |
| See, PA | 1 |
| Singh, H | 1 |
| de Leon, RD | 1 |
| Miyazato, M | 4 |
| Sugaya, K | 4 |
| Nishijima, S | 4 |
| Ashitomi, K | 2 |
| Hatano, T | 1 |
| Ogawa, Y | 4 |
| Morozumi, M | 2 |
| Ohyama, C | 1 |
| Kadekawa, K | 1 |
| Ashimine, S | 1 |
| Zimmer, MB | 1 |
| Goshgarian, HG | 1 |
| Kitzman, P | 1 |
| Diaz-Ruiz, A | 1 |
| Salgado-Ceballos, H | 1 |
| Montes, S | 1 |
| Maldonado, V | 1 |
| Tristan, L | 1 |
| Alcaraz-Zubeldia, M | 1 |
| Ríos, C | 1 |
| Martinez, M | 2 |
| Hernandez, M | 1 |
| Furst, C | 1 |
| Huang, J | 1 |
| Frydel, BR | 1 |
| Gómez-Marín, O | 1 |
| Quintero Wolfe, SC | 1 |
| Cumberbatch, N | 1 |
| Menendez, I | 1 |
| Eaton, M | 1 |
| Simpson, RK | 3 |
| Robertson, CS | 3 |
| Goodman, JC | 3 |
| Gondo, M | 1 |
| Shapiro, S | 1 |
| Brock, MV | 1 |
| Redmond, JM | 1 |
| Ishiwa, S | 1 |
| Johnston, MV | 1 |
| Baumgartner, WA | 1 |
| Laschinger, JC | 1 |
| Williams, GM | 1 |
| Green, CS | 1 |
| Soffe, SR | 1 |
| Agrawal, SK | 1 |
| Theriault, E | 1 |
| Fehlings, MG | 1 |
| McAdoo, DJ | 1 |
| Xu, GY | 1 |
| Robak, G | 1 |
| Hughes, MG | 1 |
| Lindå, H | 1 |
| Shupliakov, O | 1 |
| Ornung, G | 1 |
| Ottersen, OP | 1 |
| Storm-Mathisen, J | 1 |
| Risling, M | 1 |
| Cullheim, S | 1 |
| Tonai, T | 1 |
| Shiba, K | 1 |
| Taketani, Y | 1 |
| Ohmoto, Y | 1 |
| Murata, K | 1 |
| Muraguchi, M | 1 |
| Ohsaki, H | 1 |
| Takeda, E | 1 |
| Nishisho, T | 1 |
| Smith, CP | 1 |
| Somogyi, GT | 1 |
| Bird, ET | 1 |
| Chancellor, MB | 1 |
| Boone, TB | 1 |
| Mills, CD | 1 |
| Johnson, KM | 1 |
| Hulsebosch, CE | 1 |
| Panter, SS | 1 |
| Yum, SW | 1 |
| Demediuk, P | 1 |
| Daly, MP | 1 |
| DeGroat, WC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Priming With High-Frequency Trans-spinal Stimulation to Augment Locomotor Benefits in Spinal Cord Injury[NCT04807764] | 45 participants (Anticipated) | Interventional | 2021-08-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for glycine and Injuries, Spinal Cord
| Article | Year |
|---|---|
Differential effects of spinal cord transection on glycinergic and GABAergic synaptic signaling in sub-lesional lumbar motoneurons.
Topics: Animals; gamma-Aminobutyric Acid; Glycine; Motor Neurons; Rats; Receptors, GABA-A; Receptors, Glycin | 2021 |
Chapter 1--importance of chloride homeostasis in the operation of rhythmic motor networks.
Topics: Animals; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; Glycine; Homeostasis; Locomotion; Memb | 2011 |
Neurotransmission by neurons that use serotonin, noradrenaline, glutamate, glycine, and gamma-aminobutyric acid in the normal and injured spinal cord.
Topics: Animals; Ganglia, Spinal; Glutamic Acid; Glycine; Humans; Interneurons; Motor Neurons; Neural Inhibi | 1997 |
40 other studies available for glycine and Injuries, Spinal Cord
| Article | Year |
|---|---|
Opposite, bidirectional shifts in excitation and inhibition in specific types of dorsal horn interneurons are associated with spasticity and pain post-SCI.
Topics: Action Potentials; Animals; Chronic Pain; gamma-Aminobutyric Acid; Glycine; Interneurons; Male; Musc | 2017 |
Changes in innervation of lumbar motoneurons and organization of premotor network following training of transected adult rats.
Topics: Animals; Female; gamma-Aminobutyric Acid; Glycine; Hindlimb; Interneurons; Locomotion; Lumbosacral R | 2018 |
Neutrophil elastase inhibition effectively rescued angiopoietin-1 decrease and inhibits glial scar after spinal cord injury.
Topics: Angiopoietin-1; Angiopoietin-2; Animals; Cicatrix; Cytokines; Disease Models, Animal; Endothelial Ce | 2018 |
Overexpression of BDNF increases excitability of the lumbar spinal network and leads to robust early locomotor recovery in completely spinalized rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Dependovirus; gamma-Aminobutyric Acid; Genetic Vectors; | 2014 |
Neuronal release and successful astrocyte uptake of aminoacidergic neurotransmitters after spinal cord injury in lampreys.
Topics: Animals; Astrocytes; Axons; Fish Proteins; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; | 2014 |
Dynamic membrane depolarization is an early regulator of ependymoglial cell response to spinal cord injury in axolotl.
Topics: Ambystoma mexicanum; Animals; Axons; Cell Proliferation; Disease Models, Animal; Ependymoglial Cells | 2015 |
Stabilization of HIF-1α by FG-4592 promotes functional recovery and neural protection in experimental spinal cord injury.
Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Female; Glycine; Hypoxia-Inducible Factor | 2016 |
GAPDH/Siah1 cascade is involved in traumatic spinal cord injury and could be attenuated by sivelestat sodium.
Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Disease Models, Animal; Drug Evaluation, Preclin | 2016 |
Effects of glycine on motor performance in rats after traumatic spinal cord injury.
Topics: Animals; Glycine; Male; Psychomotor Performance; Rats; Rats, Wistar; Spinal Cord Injuries; Walking | 2007 |
Better functional outcome of compression spinal cord injury in mice is associated with enhanced H-reflex responses.
Topics: Analysis of Variance; Animals; Biophysics; Cell Adhesion Molecules; Choline O-Acetyltransferase; Dis | 2009 |
Protective effect of sivelestat sodium hydrate (ONO-5046) on ischemic spinal cord injury.
Topics: Animals; Apoptosis; Disease Models, Animal; Glycine; Infusions, Intra-Arterial; Leukocyte Elastase; | 2009 |
Clinical feasibility for cell therapy using human neuronal cell line to treat neuropathic behavioral hypersensitivity following spinal cord injury in rats.
Topics: Animals; Behavior, Animal; Cell Line; Cell- and Tissue-Based Therapy; Excitatory Amino Acid Agonists | 2009 |
Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents.
Topics: Analysis of Variance; Animals; Animals, Newborn; Calcium-Binding Proteins; CD11b Antigen; Cells, Cul | 2009 |
Down-regulation of the potassium-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury.
Topics: Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Carboxylic Acids; Chloride Channels; | 2010 |
Differential plasticity of the GABAergic and glycinergic synaptic transmission to rat lumbar motoneurons after spinal cord injury.
Topics: Animals; Animals, Newborn; Brain Stem; Disease Models, Animal; Down-Regulation; Efferent Pathways; g | 2010 |
[Reduced neuronal inhibition and spasticity following spinal cord injury].
Topics: Animals; Brain-Derived Neurotrophic Factor; Chlorides; gamma-Aminobutyric Acid; Glycine; H-Reflex; H | 2011 |
Adaptations in glutamate and glycine content within the lumbar spinal cord are associated with the generation of novel gait patterns in rats following neonatal spinal cord transection.
Topics: Animals; Female; Gait; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Locomotio | 2011 |
Inhibitory effect of intrathecal glycine on the micturition reflex in normal and spinal cord injury rats.
Topics: Acute Disease; Animals; Chronic Disease; Disease Models, Animal; Female; Glutamic Acid; Glycine; Gly | 2003 |
Dietary glycine inhibits bladder activity in normal rats and rats with spinal cord injury.
Topics: Animals; Blood-Brain Barrier; Body Weight; Female; Glutamic Acid; Glycine; Rats; Rats, Sprague-Dawle | 2005 |
Rectal distention inhibits the spinal micturition reflex via glycinergic or GABAergic mechanisms in rats with spinal cord injury.
Topics: Animals; Bicuculline; Female; GABA Antagonists; Glycine; Rats; Rats, Sprague-Dawley; Receptors, GABA | 2005 |
Intrathecal or dietary glycine inhibits bladder and urethral activity in rats with spinal cord injury.
Topics: Administration, Oral; Animals; Body Weight; Dietary Supplements; Disease Models, Animal; Dose-Respon | 2005 |
GABA, not glycine, mediates inhibition of latent respiratory motor pathways after spinal cord injury.
Topics: Animals; Bicuculline; Body Weight; Efferent Pathways; Female; GABA Antagonists; gamma-Aminobutyric A | 2007 |
VGLUT1 and GLYT2 labeling of sacrocaudal motoneurons in the spinal cord injured spastic rat.
Topics: Animals; Behavior, Animal; Disease Progression; Female; Glutamic Acid; Glycine; Glycine Plasma Membr | 2007 |
Acute alterations of glutamate, glutamine, GABA, and other amino acids after spinal cord contusion in rats.
Topics: Animals; Aspartic Acid; Citrulline; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glyci | 2007 |
Subarachnoid transplant of a human neuronal cell line attenuates chronic allodynia and hyperalgesia after excitotoxic spinal cord injury in the rat.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Cell Differentiation; Cell Line; Cell Transplantation; | 2007 |
Ronald Tasker Award: Intrathecal transplantation of a human neuronal cell line for the treatment of neuropathic pain in a spinal cord injury model.
Topics: Animals; Carcinoma, Embryonal; Cell Line, Tumor; gamma-Aminobutyric Acid; Glycine; Injections, Spina | 2007 |
Glycine: an important potential component of spinal shock.
Topics: Amino Acids; Animals; Chromatography, High Pressure Liquid; Dialysis; Evoked Potentials; Glycine; Ne | 1993 |
The influence of glycine and related compounds on spinal cord injury-induced spasticity.
Topics: Animals; Electromyography; Glycine; H-Reflex; Male; Muscle Spasticity; Rabbits; Spinal Cord Injuries | 1995 |
The role of glycine in spinal shock.
Topics: Amino Acids; Animals; Electromyography; Evoked Potentials; Glycine; H-Reflex; Microdialysis; Motor C | 1996 |
Clinical markers in CSF for determining neurologic deficits after thoracoabdominal aortic aneurysm repairs.
Topics: Aged; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Central Nervous System Diseases; Excita | 1997 |
Roles of ascending inhibition during two rhythmic motor patterns in Xenopus tadpoles.
Topics: Afferent Pathways; Aminobenzoates; Anesthetics; Animals; Bungarotoxins; Cordotomy; Escape Reaction; | 1998 |
Role of group I metabotropic glutamate receptors in traumatic spinal cord white matter injury.
Topics: Age Factors; Animals; Astrocytes; Benzoates; Cycloleucine; Electrophysiology; Estrenes; Excitatory A | 1998 |
Changes in amino acid concentrations over time and space around an impact injury and their diffusion through the rat spinal cord.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Citrulline; Glutamic Acid; Glycine; Male; Microdialys | 1999 |
Ultrastructural evidence for a preferential elimination of glutamate-immunoreactive synaptic terminals from spinal motoneurons after intramedullary axotomy.
Topics: Animals; Axotomy; Cats; Dendrites; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Microscopy, Elec | 2000 |
A neutrophil elastase inhibitor (ONO-5046) reduces neurologic damage after spinal cord injury in rats.
Topics: Animals; Blood-Brain Barrier; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Gene Expression | 2001 |
Neurogenic bladder model for spinal cord injury: spinal cord microdialysis and chronic urodynamics.
Topics: Animals; Catheters, Indwelling; Disease Models, Animal; Female; Glutamic Acid; Glycine; Microdialysi | 2002 |
Group I metabotropic glutamate receptors in spinal cord injury: roles in neuroprotection and the development of chronic central pain.
Topics: Animals; Benzoates; Chronic Disease; Excitatory Amino Acid Antagonists; Glycine; Hyperalgesia; Locom | 2002 |
Alteration in extracellular amino acids after traumatic spinal cord injury.
Topics: Amino Acids; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glycine; Male; Rabbits; Sp | 1990 |
Effect of impact trauma on neurotransmitter and nonneurotransmitter amino acids in rat spinal cord.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Gluta | 1989 |
Inhibition and excitation of sacral parasympathetic neurons by visceral and cutaneous stimuli in the cat.
Topics: Action Potentials; Aminobutyrates; Animals; Cats; Colon; Electric Stimulation; Female; Ganglia, Auto | 1971 |