Page last updated: 2024-10-18

glycine and Infantile Diarrhea

glycine has been researched along with Infantile Diarrhea in 12 studies

Research Excerpts

ExcerptRelevanceReference
"In a double blind trial a glycine fortified oral glucose electrolyte solution was evaluated in a group of infants and small children (n=25) with moderate to severe dehydration due to acute diarrhoea, and was compared with a matched control group (n=26) receiving only glucose based oral rehydration solution."5.05In search of a super solution: controlled trial of glycine-glucose oral rehydration solution in infantile diarrhoea. ( Banerjee, P; Jalan, KN; Mahalanabis, D; Patra, FC; Sen, A, 1984)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's3 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Patra, FC2
Mahalanabis, D2
Jalan, KN2
Sen, A2
Banerjee, P2
Sherman, JO1
Hamly, CA1
Khachadurina, AK1
Grange, A1
Antony, TJ1
Mohan, M1
Velásquez-Jones, L1
Mota-Hernández, F1
Puente, M1
Kane, J1
Donnadieu, I1
Briones, M1
Luis de Luna, J1
Covarrubias, J1
Vega-Franco, L1
Vesikari, T1
Isolauri, E1
Marnela, KM1
Santosham, M1
Burns, BA1
Reid, R1
Letson, GW1
Duncan, B1
Powlesland, JA1
Foster, S1
Garrett, S1
Croll, L1
Nyunt Nyunt, W1
Maitra, TK1
Kumar, V1
Chase, HP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tolerability of an Amino Acid-based Oral Rehydration Solution in Children With Short Bowel Syndrome[NCT03105362]4 participants (Actual)Interventional2017-08-16Terminated (stopped due to Issues w/ sponsor and recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Average Stool Output Difference (First Week v. Second Week) for Patients in Intestinal Continuity

Output was measured as frequency of stools per day. The mean output was compared between week 1(day 1-7) and week 2 (day 8-14). The difference (of the means) between weeks were reported. (NCT03105362)
Timeframe: Total study duration 14 days

InterventionStools per day (Mean)
Primary Outcome.3

Average Stool Output Difference (First Week v. Second Week) for Patients With Ostomy

Ostomy output measured as milliliters per day. The mean of outputs where compared between week 1(day 1-7) and week 2 (day 8-14). The difference (of the means) between weeks were reported. (NCT03105362)
Timeframe: Total study duration14 days

InterventionmL/day (Mean)
Primary Outcome50

Palatability Rating of Amino Acid ORS (Enterade®) Compared to Baseline ORS

"Rating of enterade® taste was compared to previous patient baseline oral rehydration solution taste. We compared measurements using the facial hedonic method 100-mm visual analog scale (worst (0mm) and best taste(100mm)). We utilized the difference between two measurements: Day 0 (baseline ORS) and Day 14 (last study day of Amino Acid-ORS consumption). The difference was reported (Day 14 minus value at Day 0)." (NCT03105362)
Timeframe: 14 days

Interventionmm (Mean)
Outcome Measure (3)0

Tolerance: Reported Episodes of Abdominal Distension and Emesis

Number of episodes reported of abdominal distension and emesis during study period (NCT03105362)
Timeframe: 14 days

InterventionEpisodes (Number)
Reported episodes of Abdominal DistensionReported episodes of Emesis
Outcome Measure (2)00

Reviews

1 review available for glycine and Infantile Diarrhea

ArticleYear
Impact of glycine-containing ORS solutions on stool output and duration of diarrhoea: a meta-analysis of seven clinical trials. The International Study Group on Improved ORS.
    Bulletin of the World Health Organization, 1991, Volume: 69, Issue:5

    Topics: Body Weight; Child, Preschool; Confidence Intervals; Diarrhea, Infantile; Glucose; Glycine; Humans;

1991

Trials

5 trials available for glycine and Infantile Diarrhea

ArticleYear
In search of a super solution: controlled trial of glycine-glucose oral rehydration solution in infantile diarrhoea.
    Acta paediatrica Scandinavica, 1984, Volume: 73, Issue:1

    Topics: Administration, Oral; Child, Preschool; Clinical Trials as Topic; Dehydration; Diarrhea, Infantile;

1984
Evaluation of malto-dextrin/glycine oral rehydration solution.
    Annals of tropical paediatrics, 1992, Volume: 12, Issue:4

    Topics: Diarrhea, Infantile; Double-Blind Method; Fluid Therapy; Glucose; Glycine; Humans; Infant; Male; Pol

1992
Comparison of glucose/electrolyte and maltodextrin/glycine/glycyl-glycine/electrolyte oral rehydration solutions in acute diarrhea in children.
    Journal of pediatric gastroenterology and nutrition, 1991, Volume: 13, Issue:4

    Topics: Acute Disease; Breast Feeding; Child, Preschool; Citrates; Defecation; Diarrhea; Diarrhea, Infantile

1991
A comparative study of glycine fortified oral rehydration solution with standard WHO oral rehydration solution.
    Indian pediatrics, 1989, Volume: 26, Issue:12

    Topics: Administration, Oral; Child, Preschool; Diarrhea, Infantile; Fluid Therapy; Glycine; Humans; Infant;

1989
Glycine-based oral rehydration solution: reassessment of safety and efficacy.
    The Journal of pediatrics, 1986, Volume: 109, Issue:5

    Topics: Anti-Bacterial Agents; Arizona; Bacterial Infections; Clinical Trials as Topic; Dehydration; Diarrhe

1986

Other Studies

6 other studies available for glycine and Infantile Diarrhea

ArticleYear
Use of an oral elemental diet in infants with severe intractable diarrhea.
    The Journal of pediatrics, 1975, Volume: 86, Issue:4

    Topics: Acid-Base Equilibrium; Administration, Oral; Alanine Transaminase; Amino Acids; Blood Urea Nitrogen;

1975
Effect of an oral rehydration solution with glycine and glycylglycine in infants with acute diarrhoea.
    Journal of tropical pediatrics, 1989, Volume: 35, Issue:1

    Topics: Diarrhea, Infantile; Fluid Therapy; Glycine; Humans; Infant; Male; Mexico; World Health Organization

1989
[Use of a saline solution, with oligosaccharides and glycine, for oral rehydration].
    Boletin medico del Hospital Infantil de Mexico, 1988, Volume: 45, Issue:7

    Topics: Diarrhea, Infantile; Female; Fluid Therapy; Glucose; Glycine; Humans; Infant; Male

1988
Glycinuria following administration of glycine-supplemented oral rehydration solution in rotavirus diarrhoea.
    Acta paediatrica Scandinavica, 1988, Volume: 77, Issue:1

    Topics: Diarrhea, Infantile; Electrolytes; Female; Fluid Therapy; Glycine; Humans; Infant; Male; Rotavirus I

1988
A controlled clinical trial of rice and glycine-containing oral rehydration solution in acute diarrhoea in children.
    Journal of diarrhoeal diseases research, 1986, Volume: 4, Issue:1

    Topics: Child, Preschool; Diarrhea; Diarrhea, Infantile; Fluid Therapy; Glycine; Humans; Infant; Oryza

1986
Undernutrition and intestinal dipeptide hydrolase activity in the rat.
    The Journal of nutrition, 1971, Volume: 101, Issue:11

    Topics: Age Factors; Alkaline Phosphatase; Animals; Diarrhea, Infantile; Dipeptidases; Female; Glycine; Glyc

1971