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glycine and Hypoxia-Ischemia, Brain

glycine has been researched along with Hypoxia-Ischemia, Brain in 14 studies

Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.

Research Excerpts

ExcerptRelevanceReference
"HI and hypoxia were associated with a significant increase in the ratio of acyl-CoA:CoA, which was prevented by treatment with carnitine."7.73Carnitine treatment inhibits increases in cerebral carnitine esters and glutamate detected by mass spectrometry after hypoxia-ischemia in newborn rats. ( Chace, DH; Kohli, R; Wainwright, MS; Whitington, PF, 2006)
" Overactivation of the N-methyl-D-aspartate receptor (NMDAr) plays a central role in the pathogenesis of cerebral hypoxia-ischemia, but the role of both endogenous NMDAr co-agonists D-serine and glycine remains largely elusive."3.78Increased concentrations of both NMDA receptor co-agonists D-serine and glycine in global ischemia: a potential novel treatment target for perinatal asphyxia. ( Berger, R; de Barse, MM; de Koning, TJ; Fuchs, SA; Klomp, LW; Peeters-Scholte, CM; Roeleveld, MW, 2012)
"HI and hypoxia were associated with a significant increase in the ratio of acyl-CoA:CoA, which was prevented by treatment with carnitine."3.73Carnitine treatment inhibits increases in cerebral carnitine esters and glutamate detected by mass spectrometry after hypoxia-ischemia in newborn rats. ( Chace, DH; Kohli, R; Wainwright, MS; Whitington, PF, 2006)
"CSF glycine value was related to erythrocyte count, and CSF taurine value was related to its plasmatic level."2.69Glycine and other neurotransmitter amino acids in cerebrospinal fluid in perinatal asphyxia and neonatal hypoxic-ischaemic encephalopathy. ( Deulofeu, R; Figueras-Aloy, J; Jiménez, R; Roldán, A, 1999)
"Hydroxyl radicals formation was evaluated, after a 3 hr postoperative delay, by measuring the 2,3-DHBA levels by HPLC/EC before, during and over 3 hr after the administration of glutamatergic agonists or antagonists."1.31N-methyl-D-aspartate but not glutamate induces the release of hydroxyl radicals in the neonatal rat: modulation by group I metabotropic glutamate receptors. ( Barbanel, G; Cambonie, G; Kamenka, JM; Laplanche, L, 2000)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's5 (35.71)29.6817
2010's6 (42.86)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Kuan, CY1
Chen, HR1
Gao, N1
Kuo, YM1
Chen, CW1
Yang, D1
Kinkaid, MM1
Hu, E1
Sun, YY1
Cai, CC1
Zhu, JH1
Ye, LX1
Dai, YY1
Fang, MC1
Hu, YY1
Pan, SL1
Chen, S1
Li, PJ1
Fu, XQ1
Lin, ZL1
Mori, H1
Momosaki, K1
Kido, J1
Naramura, T1
Tanaka, K1
Matsumoto, S1
Nakamura, K1
Mitsubuchi, H1
Endo, F1
Iwai, M1
Li, C1
Yan, Z1
Yang, J1
Chen, H1
Li, H1
Jiang, Y1
Zhang, Z1
Banks, P1
Franks, NP1
Dickinson, R1
Ikegame, Y1
Yamashita, K1
Hayashi, S1
Yoshimura, S1
Nakashima, S1
Iwama, T1
Fuchs, SA1
Peeters-Scholte, CM1
de Barse, MM1
Roeleveld, MW1
Klomp, LW1
Berger, R1
de Koning, TJ1
Kvrivishvili, G1
Sánchez-Pérez, AM1
Montoliu, C1
Felipo, V1
Wainwright, MS1
Kohli, R1
Whitington, PF1
Chace, DH1
Gücüyener, K1
Atalay, Y1
Aral, YZ1
Hasanoğlu, A1
Türkyilmaz, C1
Biberoglu, G1
Roldán, A1
Figueras-Aloy, J1
Deulofeu, R1
Jiménez, R1
Cambonie, G1
Laplanche, L1
Kamenka, JM1
Barbanel, G1
Panigrahy, A1
Rosenberg, PA1
Assmann, S1
Foley, EC1
Kinney, HC1

Reviews

2 reviews available for glycine and Hypoxia-Ischemia, Brain

ArticleYear
Glycine and neuroprotective effect of hypothermia in hypoxic-ischemic brain damage.
    Neuroreport, 2002, Nov-15, Volume: 13, Issue:16

    Topics: Animals; Glutamic Acid; Glycine; Humans; Hypothermia; Hypoxia-Ischemia, Brain

2002
Trialkylglycines: a new family of compounds with in vivo neuroprotective activity.
    CNS drug reviews, 2003,Fall, Volume: 9, Issue:3

    Topics: Animals; Cells, Cultured; Combinatorial Chemistry Techniques; Drug Evaluation, Preclinical; Excitato

2003

Trials

1 trial available for glycine and Hypoxia-Ischemia, Brain

ArticleYear
Glycine and other neurotransmitter amino acids in cerebrospinal fluid in perinatal asphyxia and neonatal hypoxic-ischaemic encephalopathy.
    Acta paediatrica (Oslo, Norway : 1992), 1999, Volume: 88, Issue:10

    Topics: Analysis of Variance; Aspartic Acid; Asphyxia Neonatorum; Chi-Square Distribution; Chromatography, H

1999

Other Studies

11 other studies available for glycine and Hypoxia-Ischemia, Brain

ArticleYear
Brain-targeted hypoxia-inducible factor stabilization reduces neonatal hypoxic-ischemic brain injury.
    Neurobiology of disease, 2021, Volume: 148

    Topics: Administration, Intranasal; Animals; Animals, Newborn; Cell Survival; Enzyme Inhibitors; Erythropoie

2021
Glycine Protects against Hypoxic-Ischemic Brain Injury by Regulating Mitochondria-Mediated Autophagy via the AMPK Pathway.
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Autophagy; Glycine; Hypoxia-Ischemia, Brain; Mitophag

2019
Amelioration by glycine of brain damage in neonatal rat brain following hypoxia-ischemia.
    Pediatrics international : official journal of the Japan Pediatric Society, 2017, Volume: 59, Issue:3

    Topics: Animals; Biomarkers; Brain; Glycine; Hypoxia-Ischemia, Brain; Injections, Intraperitoneal; Neuroprot

2017
Neuroprotective effects of resveratrol on ischemic injury mediated by modulating the release of neurotransmitter and neuromodulator in rats.
    Neurochemistry international, 2010, Volume: 56, Issue:3

    Topics: Animals; Antioxidants; Brain; Brain Infarction; Disease Models, Animal; Ethanolamines; Excitatory Po

2010
Competitive inhibition at the glycine site of the N-methyl-D-aspartate receptor mediates xenon neuroprotection against hypoxia-ischemia.
    Anesthesiology, 2010, Volume: 112, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Binding, Competitive; Coloring Agents; Excitatory Amino Acid Antag

2010
Neutrophil elastase inhibitor prevents ischemic brain damage via reduction of vasogenic edema.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:7

    Topics: Acute Disease; Angiopoietin-1; Animals; Blood-Brain Barrier; Brain Edema; Capillary Permeability; Ce

2010
Increased concentrations of both NMDA receptor co-agonists D-serine and glycine in global ischemia: a potential novel treatment target for perinatal asphyxia.
    Amino acids, 2012, Volume: 43, Issue:1

    Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Cell Line, Tumor; Glycine; Humans; Hypoxia; Hypoxia-

2012
Carnitine treatment inhibits increases in cerebral carnitine esters and glutamate detected by mass spectrometry after hypoxia-ischemia in newborn rats.
    Stroke, 2006, Volume: 37, Issue:2

    Topics: Animals; Animals, Newborn; Anions; Brain; Cardiolipins; Carnitine; Carnitine O-Acetyltransferase; Gl

2006
Excitatory amino acids and taurine levels in cerebrospinal fluid of hypoxic ischemic encephalopathy in newborn.
    Clinical neurology and neurosurgery, 1999, Volume: 101, Issue:3

    Topics: Aspartic Acid; Asphyxia Neonatorum; Case-Control Studies; Excitatory Amino Acids; Female; Follow-Up

1999
N-methyl-D-aspartate but not glutamate induces the release of hydroxyl radicals in the neonatal rat: modulation by group I metabotropic glutamate receptors.
    Journal of neuroscience research, 2000, Oct-01, Volume: 62, Issue:1

    Topics: Animals; Animals, Newborn; Corpus Striatum; Dose-Response Relationship, Drug; Excitatory Amino Acid

2000
Differential expression of glutamate receptor subtypes in human brainstem sites involved in perinatal hypoxia-ischemia.
    The Journal of comparative neurology, 2000, Nov-13, Volume: 427, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid;

2000
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