glycine and Hypoxia-Ischemia, Brain
glycine has been researched along with Hypoxia-Ischemia, Brain in 14 studies
Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"HI and hypoxia were associated with a significant increase in the ratio of acyl-CoA:CoA, which was prevented by treatment with carnitine." | 7.73 | Carnitine treatment inhibits increases in cerebral carnitine esters and glutamate detected by mass spectrometry after hypoxia-ischemia in newborn rats. ( Chace, DH; Kohli, R; Wainwright, MS; Whitington, PF, 2006) |
" Overactivation of the N-methyl-D-aspartate receptor (NMDAr) plays a central role in the pathogenesis of cerebral hypoxia-ischemia, but the role of both endogenous NMDAr co-agonists D-serine and glycine remains largely elusive." | 3.78 | Increased concentrations of both NMDA receptor co-agonists D-serine and glycine in global ischemia: a potential novel treatment target for perinatal asphyxia. ( Berger, R; de Barse, MM; de Koning, TJ; Fuchs, SA; Klomp, LW; Peeters-Scholte, CM; Roeleveld, MW, 2012) |
"HI and hypoxia were associated with a significant increase in the ratio of acyl-CoA:CoA, which was prevented by treatment with carnitine." | 3.73 | Carnitine treatment inhibits increases in cerebral carnitine esters and glutamate detected by mass spectrometry after hypoxia-ischemia in newborn rats. ( Chace, DH; Kohli, R; Wainwright, MS; Whitington, PF, 2006) |
"CSF glycine value was related to erythrocyte count, and CSF taurine value was related to its plasmatic level." | 2.69 | Glycine and other neurotransmitter amino acids in cerebrospinal fluid in perinatal asphyxia and neonatal hypoxic-ischaemic encephalopathy. ( Deulofeu, R; Figueras-Aloy, J; Jiménez, R; Roldán, A, 1999) |
"Hydroxyl radicals formation was evaluated, after a 3 hr postoperative delay, by measuring the 2,3-DHBA levels by HPLC/EC before, during and over 3 hr after the administration of glutamatergic agonists or antagonists." | 1.31 | N-methyl-D-aspartate but not glutamate induces the release of hydroxyl radicals in the neonatal rat: modulation by group I metabotropic glutamate receptors. ( Barbanel, G; Cambonie, G; Kamenka, JM; Laplanche, L, 2000) |
Research
Studies (14)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (14.29) | 18.2507 |
2000's | 5 (35.71) | 29.6817 |
2010's | 6 (42.86) | 24.3611 |
2020's | 1 (7.14) | 2.80 |
Authors
Authors | Studies |
---|---|
Kuan, CY | 1 |
Chen, HR | 1 |
Gao, N | 1 |
Kuo, YM | 1 |
Chen, CW | 1 |
Yang, D | 1 |
Kinkaid, MM | 1 |
Hu, E | 1 |
Sun, YY | 1 |
Cai, CC | 1 |
Zhu, JH | 1 |
Ye, LX | 1 |
Dai, YY | 1 |
Fang, MC | 1 |
Hu, YY | 1 |
Pan, SL | 1 |
Chen, S | 1 |
Li, PJ | 1 |
Fu, XQ | 1 |
Lin, ZL | 1 |
Mori, H | 1 |
Momosaki, K | 1 |
Kido, J | 1 |
Naramura, T | 1 |
Tanaka, K | 1 |
Matsumoto, S | 1 |
Nakamura, K | 1 |
Mitsubuchi, H | 1 |
Endo, F | 1 |
Iwai, M | 1 |
Li, C | 1 |
Yan, Z | 1 |
Yang, J | 1 |
Chen, H | 1 |
Li, H | 1 |
Jiang, Y | 1 |
Zhang, Z | 1 |
Banks, P | 1 |
Franks, NP | 1 |
Dickinson, R | 1 |
Ikegame, Y | 1 |
Yamashita, K | 1 |
Hayashi, S | 1 |
Yoshimura, S | 1 |
Nakashima, S | 1 |
Iwama, T | 1 |
Fuchs, SA | 1 |
Peeters-Scholte, CM | 1 |
de Barse, MM | 1 |
Roeleveld, MW | 1 |
Klomp, LW | 1 |
Berger, R | 1 |
de Koning, TJ | 1 |
Kvrivishvili, G | 1 |
Sánchez-Pérez, AM | 1 |
Montoliu, C | 1 |
Felipo, V | 1 |
Wainwright, MS | 1 |
Kohli, R | 1 |
Whitington, PF | 1 |
Chace, DH | 1 |
Gücüyener, K | 1 |
Atalay, Y | 1 |
Aral, YZ | 1 |
Hasanoğlu, A | 1 |
Türkyilmaz, C | 1 |
Biberoglu, G | 1 |
Roldán, A | 1 |
Figueras-Aloy, J | 1 |
Deulofeu, R | 1 |
Jiménez, R | 1 |
Cambonie, G | 1 |
Laplanche, L | 1 |
Kamenka, JM | 1 |
Barbanel, G | 1 |
Panigrahy, A | 1 |
Rosenberg, PA | 1 |
Assmann, S | 1 |
Foley, EC | 1 |
Kinney, HC | 1 |
Reviews
2 reviews available for glycine and Hypoxia-Ischemia, Brain
Article | Year |
---|---|
Glycine and neuroprotective effect of hypothermia in hypoxic-ischemic brain damage.
Topics: Animals; Glutamic Acid; Glycine; Humans; Hypothermia; Hypoxia-Ischemia, Brain | 2002 |
Trialkylglycines: a new family of compounds with in vivo neuroprotective activity.
Topics: Animals; Cells, Cultured; Combinatorial Chemistry Techniques; Drug Evaluation, Preclinical; Excitato | 2003 |
Trials
1 trial available for glycine and Hypoxia-Ischemia, Brain
Article | Year |
---|---|
Glycine and other neurotransmitter amino acids in cerebrospinal fluid in perinatal asphyxia and neonatal hypoxic-ischaemic encephalopathy.
Topics: Analysis of Variance; Aspartic Acid; Asphyxia Neonatorum; Chi-Square Distribution; Chromatography, H | 1999 |
Other Studies
11 other studies available for glycine and Hypoxia-Ischemia, Brain
Article | Year |
---|---|
Brain-targeted hypoxia-inducible factor stabilization reduces neonatal hypoxic-ischemic brain injury.
Topics: Administration, Intranasal; Animals; Animals, Newborn; Cell Survival; Enzyme Inhibitors; Erythropoie | 2021 |
Glycine Protects against Hypoxic-Ischemic Brain Injury by Regulating Mitochondria-Mediated Autophagy via the AMPK Pathway.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Autophagy; Glycine; Hypoxia-Ischemia, Brain; Mitophag | 2019 |
Amelioration by glycine of brain damage in neonatal rat brain following hypoxia-ischemia.
Topics: Animals; Biomarkers; Brain; Glycine; Hypoxia-Ischemia, Brain; Injections, Intraperitoneal; Neuroprot | 2017 |
Neuroprotective effects of resveratrol on ischemic injury mediated by modulating the release of neurotransmitter and neuromodulator in rats.
Topics: Animals; Antioxidants; Brain; Brain Infarction; Disease Models, Animal; Ethanolamines; Excitatory Po | 2010 |
Competitive inhibition at the glycine site of the N-methyl-D-aspartate receptor mediates xenon neuroprotection against hypoxia-ischemia.
Topics: Anesthetics, Inhalation; Animals; Binding, Competitive; Coloring Agents; Excitatory Amino Acid Antag | 2010 |
Neutrophil elastase inhibitor prevents ischemic brain damage via reduction of vasogenic edema.
Topics: Acute Disease; Angiopoietin-1; Animals; Blood-Brain Barrier; Brain Edema; Capillary Permeability; Ce | 2010 |
Increased concentrations of both NMDA receptor co-agonists D-serine and glycine in global ischemia: a potential novel treatment target for perinatal asphyxia.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Cell Line, Tumor; Glycine; Humans; Hypoxia; Hypoxia- | 2012 |
Carnitine treatment inhibits increases in cerebral carnitine esters and glutamate detected by mass spectrometry after hypoxia-ischemia in newborn rats.
Topics: Animals; Animals, Newborn; Anions; Brain; Cardiolipins; Carnitine; Carnitine O-Acetyltransferase; Gl | 2006 |
Excitatory amino acids and taurine levels in cerebrospinal fluid of hypoxic ischemic encephalopathy in newborn.
Topics: Aspartic Acid; Asphyxia Neonatorum; Case-Control Studies; Excitatory Amino Acids; Female; Follow-Up | 1999 |
N-methyl-D-aspartate but not glutamate induces the release of hydroxyl radicals in the neonatal rat: modulation by group I metabotropic glutamate receptors.
Topics: Animals; Animals, Newborn; Corpus Striatum; Dose-Response Relationship, Drug; Excitatory Amino Acid | 2000 |
Differential expression of glutamate receptor subtypes in human brainstem sites involved in perinatal hypoxia-ischemia.
Topics: 2-Amino-5-phosphonovalerate; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; | 2000 |