Page last updated: 2024-10-18

glycine and Hypertrophy

glycine has been researched along with Hypertrophy in 20 studies

Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).

Research Excerpts

ExcerptRelevanceReference
"Glycine (Gly) lowers hypercholesterolemia, hypertriglyceridemia and hypertension but its role in preventing adipocyte hypertrophy and modulating enzymatic activity of adipocytes has not been studied."7.83Effect of Glycine on Adipocyte Hypertrophy in a Metabolic Syndrome Rat Model. ( Castro, ES; Díaz-Díaz, E; Espejel, RV; Lans, VG; López, YR; Pérez-Torres, I; Zúñiga-Muñoz, A, 2016)
"Obesity was found to be associated with decreased vessel H2S concentration, inward hypertrophic remodeling, altered collagen-to-elastin ratio, and reduced vessel stiffness."5.43Hydrogen sulfide depletion contributes to microvascular remodeling in obesity. ( Candela, J; Velmurugan, GV; White, C, 2016)
"Glycine (Gly) lowers hypercholesterolemia, hypertriglyceridemia and hypertension but its role in preventing adipocyte hypertrophy and modulating enzymatic activity of adipocytes has not been studied."3.83Effect of Glycine on Adipocyte Hypertrophy in a Metabolic Syndrome Rat Model. ( Castro, ES; Díaz-Díaz, E; Espejel, RV; Lans, VG; López, YR; Pérez-Torres, I; Zúñiga-Muñoz, A, 2016)
"Obesity was found to be associated with decreased vessel H2S concentration, inward hypertrophic remodeling, altered collagen-to-elastin ratio, and reduced vessel stiffness."1.43Hydrogen sulfide depletion contributes to microvascular remodeling in obesity. ( Candela, J; Velmurugan, GV; White, C, 2016)
" Furthermore, studying brain adaptations to chronic administration of glycine site agonists may provide insights into the therapeutic mechanisms of these drugs."1.31Chronic high-dose glycine nutrition: effects on rat brain cell morphology. ( Heresco-Levy, U; Javitt, DC; Shoham, S, 2001)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19908 (40.00)18.7374
1990's3 (15.00)18.2507
2000's3 (15.00)29.6817
2010's6 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Browe, DC1
Coleman, CM1
Barry, FP1
Elliman, SJ1
Piron, L1
Deshayes, E1
Escal, L1
Souche, R1
Herrero, A1
Pierredon-Foulongne, MA1
Assenat, E1
le Lam, N1
Quenet, F1
Guiu, B1
Lunardi, A1
Cervelli, R1
Volterrani, D1
Vitali, S1
Lombardo, C1
Lorenzoni, G1
Crocetti, L1
Bargellini, I1
Campani, D1
Pollina, LE1
Cioni, R1
Caramella, D1
Boggi, U1
Candela, J1
Velmurugan, GV1
White, C1
López, YR1
Pérez-Torres, I1
Zúñiga-Muñoz, A1
Lans, VG1
Díaz-Díaz, E1
Castro, ES1
Espejel, RV1
El-Sayed, SS1
Zakaria, MN1
Abdel-Ghany, RH1
Abdel-Rahman, AA1
Kleopa, KA1
Sutton, LN1
Ong, J1
Tennekoon, G1
Telfeian, AE1
FEINBLATT, HM1
GANT, JC1
WAGLE, SR1
ASHMORE, J1
LEVINE, AS1
Koh, TJ1
Dockray, GJ1
Varro, A1
Cahill, RJ1
Dangler, CA1
Fox, JG1
Wang, TC1
Shoham, S1
Javitt, DC1
Heresco-Levy, U1
Al Banchaabouchi, M1
Marescau, B1
Van Marck, E1
D'hooge, R1
De Deyn, PP1
Heyman, SN1
Brezis, M1
Epstein, FH1
Spokes, K1
Rosen, S1
Shimamura, T1
Milsom, JP1
Craig, RD1
Ripa, R1
Frisoni, B1
Pignatari, S1
Robinson, JW1
Borgeaud, J1
Mirkovitch, V1
Tomashefsky, P1
Tannenbaum, M1
Zimmer, HG1
Marko, P1
Kammermeier, H1
Schwarzmeier, J1
Krautzberger, W1
Gourley, DR1
Gerlach, E1
Pain, VM1
Manchester, KL1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Trial of the Effects of Glycine Loading on Clinical Symptoms and Logical Memory in Patients With Schizophrenia[NCT00575848]Phase 116 participants (Anticipated)Interventional2007-12-31Terminated (stopped due to Slow enrollment and due to personnel change there was no viable way to quantify glycine levels through imaging)
The Effects of Glycine Transport Inhibition on Brain Glycine Concentration[NCT00538070]68 participants (Actual)Interventional2007-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for glycine and Hypertrophy

ArticleYear
[Portal vein embolization: Present and future].
    Bulletin du cancer, 2017, Volume: 104, Issue:5

    Topics: Aniline Compounds; Chemotherapy, Adjuvant; Cyanoacrylates; Embolization, Therapeutic; Glycine; Hepat

2017

Other Studies

19 other studies available for glycine and Hypertrophy

ArticleYear
Hypoxia Activates the PTHrP -MEF2C Pathway to Attenuate Hypertrophy in Mesenchymal Stem Cell Derived Cartilage.
    Scientific reports, 2019, 09-16, Volume: 9, Issue:1

    Topics: Anaerobiosis; Animals; Cartilage, Articular; Cell Hypoxia; Cell Line, Tumor; Chondrocytes; Chondroge

2019
Feasibility of Percutaneous Intrahepatic Split by Microwave Ablation (PISA) After Portal Vein Embolization for Hypertrophy of Future Liver Remnant: The Radiological Stage-1 ALPPS.
    Cardiovascular and interventional radiology, 2018, Volume: 41, Issue:5

    Topics: Ablation Techniques; Aged; Aniline Compounds; Embolization, Therapeutic; Feasibility Studies; Female

2018
Hydrogen sulfide depletion contributes to microvascular remodeling in obesity.
    American journal of physiology. Heart and circulatory physiology, 2016, 05-01, Volume: 310, Issue:9

    Topics: Alkynes; Animals; Arterioles; Cells, Cultured; Collagen; Collagenases; Cystathionine gamma-Lyase; Di

2016
Effect of Glycine on Adipocyte Hypertrophy in a Metabolic Syndrome Rat Model.
    Current drug delivery, 2016, Volume: 13, Issue:1

    Topics: Adipocytes; Adipose Tissue; Animals; Blood Pressure; Fatty Acids; Glycine; Hypertrophy; Insulin; Lip

2016
Cystathionine-γ lyase-derived hydrogen sulfide mediates the cardiovascular protective effects of moxonidine in diabetic rats.
    European journal of pharmacology, 2016, Jul-15, Volume: 783

    Topics: Adiponectin; Alkynes; Animals; Baroreflex; Blood Glucose; Body Weight; Cardiotonic Agents; Cystathio

2016
Conus medulla-cauda compression from nerve root hypertrophy in a child with Dejerine-Sottas syndrome: improvement with laminectomy and duraplasty. Case report.
    Journal of neurosurgery, 2002, Volume: 97, Issue:2 Suppl

    Topics: Amino Acid Substitution; Arginine; Child; Codon; Decompression, Surgical; Glycine; Hereditary Sensor

2002
Palliative treatment of benign prostatic hypertrophy; value of glycine-alanine-glutamic acid combination.
    The Journal of the Maine Medical Association, 1958, Volume: 49, Issue:3

    Topics: Alanine; Dipeptides; Fabaceae; Glutamates; Glutamic Acid; Glycine; Humans; Hypertrophy; Male; Pallia

1958
STUDIES ON AMINO ACID INCORPORATION INTO PROTEIN OF TUMORS INDUCED BY ROUS SARCOMA VIRUS AND HYPERPLASIA INDUCED BY FOWL POX VIRUS IN CHORIOALLANTOIC MEMBRANE OF CHICKEN EMBRYOS.
    Cancer research, 1963, Volume: 23

    Topics: Amino Acids; Animals; Avian Sarcoma Viruses; Chick Embryo; Chickens; Chorioallantoic Membrane; Enzym

1963
Overexpression of glycine-extended gastrin in transgenic mice results in increased colonic proliferation.
    The Journal of clinical investigation, 1999, Volume: 103, Issue:8

    Topics: Animals; Cell Division; Colon; Gastrins; Gastrointestinal Neoplasms; Gene Expression; Glycine; Goble

1999
Chronic high-dose glycine nutrition: effects on rat brain cell morphology.
    Biological psychiatry, 2001, May-15, Volume: 49, Issue:10

    Topics: Adaptation, Physiological; Animals; Antibodies, Monoclonal; Astrocytes; Brain; Calcium Channels; Cel

2001
Chronic high-dose glycine nutrition: effects on rat brain cell morphology.
    Biological psychiatry, 2001, May-15, Volume: 49, Issue:10

    Topics: Adaptation, Physiological; Animals; Antibodies, Monoclonal; Astrocytes; Brain; Calcium Channels; Cel

2001
Chronic high-dose glycine nutrition: effects on rat brain cell morphology.
    Biological psychiatry, 2001, May-15, Volume: 49, Issue:10

    Topics: Adaptation, Physiological; Animals; Antibodies, Monoclonal; Astrocytes; Brain; Calcium Channels; Cel

2001
Chronic high-dose glycine nutrition: effects on rat brain cell morphology.
    Biological psychiatry, 2001, May-15, Volume: 49, Issue:10

    Topics: Adaptation, Physiological; Animals; Antibodies, Monoclonal; Astrocytes; Brain; Calcium Channels; Cel

2001
Long-term effect of partial nephrectomy on biological parameters, kidney histology, and guanidino compound levels in mice.
    Metabolism: clinical and experimental, 2001, Volume: 50, Issue:12

    Topics: Aging; Animals; Arginine; Brain Chemistry; Creatinine; Glycine; Guanidines; Homoarginine; Humans; Hy

2001
Effect of glycine and hypertrophy on renal outer medullary hypoxic injury in ischemia reflow and contrast nephropathy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1992, Volume: 19, Issue:6

    Topics: Animals; Cell Hypoxia; Glycine; Hypertrophy; Iothalamic Acid; Kidney Medulla; Kidney Tubular Necrosi

1992
Prevention of 11-deoxycorticosterone-salt-induced glomerular hypertrophy and glomerulosclerosis by dietary phosphate binder.
    The American journal of pathology, 1990, Volume: 136, Issue:3

    Topics: Aluminum Hydroxide; Animals; Antacids; Blood Pressure; Calcium; Creatine; Desoxycorticosterone; Dise

1990
Collagen degradation in cultured keloid and hypertrophic scar tissue.
    The British journal of dermatology, 1973, Volume: 89, Issue:6

    Topics: Adolescent; Adult; Aged; Carbon Radioisotopes; Child; Child, Preschool; Cicatrix; Collagen; Culture

1973
[Effect of mercaptopropionylglycine on compensatory renal hypertrophy].
    Giornale di clinica medica, 1972, Volume: 53, Issue:11

    Topics: Amino Acids; Animals; Disease Models, Animal; Glycine; Hypertrophy; Kidney Diseases; Kidney Tubules;

1972
Glycine transport in hypertrophic rat kidneys.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1973, Jan-20, Volume: 19, Issue:1

    Topics: Animals; Biological Transport; DNA; Glycine; Hydronephrosis; Hypertrophy; Kidney; Ligation; Male; Ne

1973
Macromolecular metabolism in renal compensatory hypertrophy. I. Protein synthesis.
    Laboratory investigation; a journal of technical methods and pathology, 1969, Volume: 21, Issue:4

    Topics: Amino Acids; Animals; Body Surface Area; Carbon Isotopes; DNA; Glycine; Hypertrophy; Kidney; Leucine

1969
[Synthesis of nucleotides and proteins in the heart during pressure load and hypertrophy].
    Pflugers Archiv : European journal of physiology, 1969, Volume: 312, Issue:1

    Topics: Animals; Aortic Coarctation; Carbon Isotopes; Glycine; Heart; Hypertrophy; Muscle Proteins; Myocardi

1969
The influence of electrical stimulation in vitro on protein synthesis and other metabolic parameters of rat extensor digitorum longus muscle.
    The Biochemical journal, 1970, Volume: 118, Issue:2

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Amino Acids; Animals; Electric Stimulation; Female; Glu

1970