Page last updated: 2024-10-18

glycine and Hypernatremia

glycine has been researched along with Hypernatremia in 3 studies

Hypernatremia: Excessive amount of sodium in the blood. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Five (2%) patients had TUR syndrome; all five were irrigated with glycine, although this difference was not statistically significant (P = 0."9.11A comparison of the effect of 1.5% glycine and 5% glucose irrigants on plasma serum physiology and the incidence of transurethral resection syndrome during prostate resection. ( Bradbrook, RA; Collins, JW; Keeley, FX; Macdermott, S; Timoney, AG, 2005)
"Five (2%) patients had TUR syndrome; all five were irrigated with glycine, although this difference was not statistically significant (P = 0."5.11A comparison of the effect of 1.5% glycine and 5% glucose irrigants on plasma serum physiology and the incidence of transurethral resection syndrome during prostate resection. ( Bradbrook, RA; Collins, JW; Keeley, FX; Macdermott, S; Timoney, AG, 2005)
"Efficacy and safety of glycine fortified oral rehydration solution (ORS) was compared with a standard ORS (WHO formula) in a randomized clinical trial in children aged between 4 months and 5 yr with moderate degree of dehydration owing to acute watery diarrhoea."5.06Efficacy & safety of glycine fortified oral rehydration solution in the treatment of acute dehydrating diarrhoea in children. ( Bhattacharya, MK; Bhattacharya, SK; Dutta, D; Dutta, P; Mitra, U; Mukherjee, HN; Nashipuri, JN; Pal, SC; Sinha, AK, 1989)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Collins, JW1
Macdermott, S1
Bradbrook, RA1
Keeley, FX1
Timoney, AG1
Bhattacharya, SK1
Dutta, P1
Bhattacharya, MK1
Mukherjee, HN1
Dutta, D1
Sinha, AK1
Mitra, U1
Nashipuri, JN1
Pal, SC1
Santosham, M1
Burns, BA1
Reid, R1
Letson, GW1
Duncan, B1
Powlesland, JA1
Foster, S1
Garrett, S1
Croll, L1
Nyunt Nyunt, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tolerability of an Amino Acid-based Oral Rehydration Solution in Children With Short Bowel Syndrome[NCT03105362]4 participants (Actual)Interventional2017-08-16Terminated (stopped due to Issues w/ sponsor and recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Average Stool Output Difference (First Week v. Second Week) for Patients in Intestinal Continuity

Output was measured as frequency of stools per day. The mean output was compared between week 1(day 1-7) and week 2 (day 8-14). The difference (of the means) between weeks were reported. (NCT03105362)
Timeframe: Total study duration 14 days

InterventionStools per day (Mean)
Primary Outcome.3

Average Stool Output Difference (First Week v. Second Week) for Patients With Ostomy

Ostomy output measured as milliliters per day. The mean of outputs where compared between week 1(day 1-7) and week 2 (day 8-14). The difference (of the means) between weeks were reported. (NCT03105362)
Timeframe: Total study duration14 days

InterventionmL/day (Mean)
Primary Outcome50

Palatability Rating of Amino Acid ORS (Enterade®) Compared to Baseline ORS

"Rating of enterade® taste was compared to previous patient baseline oral rehydration solution taste. We compared measurements using the facial hedonic method 100-mm visual analog scale (worst (0mm) and best taste(100mm)). We utilized the difference between two measurements: Day 0 (baseline ORS) and Day 14 (last study day of Amino Acid-ORS consumption). The difference was reported (Day 14 minus value at Day 0)." (NCT03105362)
Timeframe: 14 days

Interventionmm (Mean)
Outcome Measure (3)0

Tolerance: Reported Episodes of Abdominal Distension and Emesis

Number of episodes reported of abdominal distension and emesis during study period (NCT03105362)
Timeframe: 14 days

InterventionEpisodes (Number)
Reported episodes of Abdominal DistensionReported episodes of Emesis
Outcome Measure (2)00

Trials

3 trials available for glycine and Hypernatremia

ArticleYear
A comparison of the effect of 1.5% glycine and 5% glucose irrigants on plasma serum physiology and the incidence of transurethral resection syndrome during prostate resection.
    BJU international, 2005, Volume: 96, Issue:3

    Topics: Absorption; Aged; Aged, 80 and over; Blood Loss, Surgical; Glucose; Glycine; Humans; Hypernatremia;

2005
Efficacy & safety of glycine fortified oral rehydration solution in the treatment of acute dehydrating diarrhoea in children.
    The Indian journal of medical research, 1989, Volume: 90

    Topics: Child, Preschool; Dehydration; Diarrhea; Glycine; Humans; Hypernatremia; Infant; Male; Randomized Co

1989
Glycine-based oral rehydration solution: reassessment of safety and efficacy.
    The Journal of pediatrics, 1986, Volume: 109, Issue:5

    Topics: Anti-Bacterial Agents; Arizona; Bacterial Infections; Clinical Trials as Topic; Dehydration; Diarrhe

1986