Page last updated: 2024-10-18

glycine and Hyperkalemia

glycine has been researched along with Hyperkalemia in 11 studies

Hyperkalemia: Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Intraventricular conduction disorders and reentrant arrhythmias in dogs can be produced by high plasma bupivacaine concentrations."7.68Enhancement by hyponatremia and hyperkalemia of ventricular conduction and rhythm disorders caused by bupivacaine. ( Bertix, L; Couzon, P; Faucon, G; Freysz, M; Mazze, R; Timour, Q, 1990)
" Additional data are needed regarding the effectiveness and safety of roxadustat as compared with standard therapy (epoetin alfa) for the treatment of anemia in patients undergoing dialysis."5.30Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis. ( Cai, GY; Chen, N; Hao, C; Hao, L; Jiang, G; Leong, R; Li, X; Liang, X; Lin, H; Liu, BC; Liu, C; Liu, Z; Luo, L; Neff, T; Szczech, L; Wang, C; Wang, J; Xing, C; Yu, KP; Zhao, MH; Zuo, L, 2019)
"Glyphosate potassium poisoning causes hyperkalemia."3.91Serial measurement of glyphosate blood concentration in a glyphosate potassium herbicide-intoxicated patient: A case report. ( Ahn, H; Cho, S; Cho, Y; Choi, H; Jeong, W; Kim, S; Min, J; Oh, S; Park, J; You, Y, 2019)
"Ingestion of glyphosate-surfactant herbicides (GlySH) can result in acute kidney injury, electrolyte abnormalities, acidosis, cardiovascular collapse, and death."3.80Hemodialysis clearance of glyphosate following a life-threatening ingestion of glyphosate-surfactant herbicide. ( Allan, MJ; Garlich, FM; Goldfarb, DS; Goldman, M; Goldstein, DA; Hoffman, RS; Nelson, LS; Pepe, J, 2014)
"Intraventricular conduction disorders and reentrant arrhythmias in dogs can be produced by high plasma bupivacaine concentrations."3.68Enhancement by hyponatremia and hyperkalemia of ventricular conduction and rhythm disorders caused by bupivacaine. ( Bertix, L; Couzon, P; Faucon, G; Freysz, M; Mazze, R; Timour, Q, 1990)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's8 (72.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cho, Y1
Jeong, W1
Kim, S1
Choi, H1
You, Y1
Cho, S1
Oh, S1
Ahn, H1
Park, J1
Min, J1
Chen, N2
Hao, C2
Peng, X1
Lin, H2
Yin, A1
Hao, L2
Tao, Y1
Liang, X2
Liu, Z3
Xing, C2
Chen, J1
Luo, L2
Zuo, L2
Liao, Y1
Liu, BC2
Leong, R2
Wang, C3
Liu, C2
Neff, T2
Szczech, L2
Yu, KP2
Jiang, G1
Li, X1
Wang, J1
Zhao, MH1
Cai, GY1
Garlich, FM1
Goldman, M1
Pepe, J1
Nelson, LS1
Allan, MJ1
Goldstein, DA1
Goldfarb, DS1
Hoffman, RS1
Kato, Y1
Bando, H1
Murao, Y1
Aoyagi, U1
Hirakawa, A1
Iwase, M1
Nakatani, T1
Kamijo, Y1
Mekari, M1
Yoshimura, K1
Kan'o, T1
Soma, K1
Zouaoui, K1
Dulaurent, S1
Gaulier, JM1
Moesch, C1
Lachâtre, G1
Stella, J1
Ryan, M1
Hahn, RG1
Timour, Q1
Freysz, M1
Mazze, R1
Couzon, P1
Bertix, L1
Faucon, G1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Efficacy and Safety of FG-4592 for Treatment of Anemia in Subjects With Chronic Kidney Disease Not on Dialysis[NCT02652819]Phase 3154 participants (Actual)Interventional2015-12-31Completed
A Randomized Controlled Trial to Evaluate the Safety and Efficacy of Roxadustat in Patients With Acute ST Elevation Myocardial Infarction[NCT04803864]Phase 2158 participants (Anticipated)Interventional2021-06-10Recruiting
Roxadustat Reduces the Incidence of Acute Kidney Injury After Coronary Artery Bypass Grafting: a Multicenter, Randomized, Double-blind, Placebo-controlled Study[NCT05010460]Phase 2318 participants (Anticipated)Interventional2021-09-30Recruiting
Roxadustat Combined With Luspatercept Versus Luspatercept Monotherapy in the Treatment of Refractory Myelodysplastic Syndrome With Ring Sideroblasts (MDS-RS): A Prospective Randomized Controlled Study[NCT06006949]Phase 462 participants (Anticipated)Interventional2023-08-31Not yet recruiting
A Phase 3, Randomized, Open-Label, Active-Controlled Study of Efficacy and Safety of FG-4592 for Treatment of Anemia in Subjects With Chronic Kidney Disease on Dialysis[NCT02652806]Phase 3305 participants (Actual)Interventional2015-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for glycine and Hyperkalemia

ArticleYear
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Acidosis; Adult; Aged; Anemia; Cholesterol; Double-Blind Method; Female; Glycine; Hematinics; Hemogl

2019
Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Adult; Aged; Analysis of Variance; Anemia; Cholesterol; Double-Blind Method; Epoetin Alfa; Female; G

2019
Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Adult; Aged; Analysis of Variance; Anemia; Cholesterol; Double-Blind Method; Epoetin Alfa; Female; G

2019
Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Adult; Aged; Analysis of Variance; Anemia; Cholesterol; Double-Blind Method; Epoetin Alfa; Female; G

2019
Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis.
    The New England journal of medicine, 2019, 09-12, Volume: 381, Issue:11

    Topics: Adult; Aged; Analysis of Variance; Anemia; Cholesterol; Double-Blind Method; Epoetin Alfa; Female; G

2019

Other Studies

9 other studies available for glycine and Hyperkalemia

ArticleYear
Serial measurement of glyphosate blood concentration in a glyphosate potassium herbicide-intoxicated patient: A case report.
    The American journal of emergency medicine, 2019, Volume: 37, Issue:8

    Topics: Aged; Arrhythmias, Cardiac; Glycine; Glyphosate; Herbicides; Humans; Hyperkalemia; Male; Nausea; Pot

2019
Hemodialysis clearance of glyphosate following a life-threatening ingestion of glyphosate-surfactant herbicide.
    Clinical toxicology (Philadelphia, Pa.), 2014, Volume: 52, Issue:1

    Topics: Acidosis; Blood Chemical Analysis; Electrocardiography; Glycine; Glyphosate; Hemodynamics; Herbicide

2014
[Three cases of an extreme hyperkalemia associated with glyphosate potassium herbicide poisoning].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2015, Volume: 28, Issue:4

    Topics: Acute Kidney Injury; Adult; Aged; Calcium Gluconate; Female; Glycine; Glyphosate; Herbicides; Humans

2015
[Extreme hyperkalemia in a patient with a new glyphosate potassium herbicide poisoning: report of a case].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2010, Volume: 23, Issue:3

    Topics: Aged; Female; Glycine; Glyphosate; Herbicides; Humans; Hyperkalemia; Potassium; Severity of Illness

2010
Glyphosate-surfactant herbicide products containing glyphosate potassium salt can cause fatal hyperkalemia if ingested in massive amounts.
    Clinical toxicology (Philadelphia, Pa.), 2012, Volume: 50, Issue:2

    Topics: Aged; Electrocardiography; Female; Glycine; Glyphosate; Herbicides; Humans; Hyperkalemia; Surface-Ac

2012
Determination of glyphosate and AMPA in blood and urine from humans: about 13 cases of acute intoxication.
    Forensic science international, 2013, Mar-10, Volume: 226, Issue:1-3

    Topics: Accidents; Acidosis; Adult; Aged; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Chro

2013
Glyphosate herbicide formulation: a potentially lethal ingestion.
    Emergency medicine Australasia : EMA, 2004, Volume: 16, Issue:3

    Topics: Acidosis; Administration, Oral; Adult; Aged; Drug Overdose; Emergency Medicine; Fatal Outcome; Glyci

2004
Hyperkalemia from nonelectrolyte solutions.
    Anesthesiology, 1993, Volume: 78, Issue:4

    Topics: Animals; Electrolytes; Glycine; Humans; Hyperkalemia; Isotonic Solutions; Male; Mannitol; Potassium;

1993
Enhancement by hyponatremia and hyperkalemia of ventricular conduction and rhythm disorders caused by bupivacaine.
    Anesthesiology, 1990, Volume: 72, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Bupivacaine; Dogs; Electrocardiography; Female; Glycine; Heart Conduc

1990